An implementation of the parameter cascade method in Ramsay, J. O., Hooker,G., Campbell, D., and Cao, J. (2007) for estimating ordinary differential equation models with missing or complete observations. It combines smoothing method and profile estimation to estimate any non-linear dynamic system. The package also offers variance estimates for parameters of interest based on either bootstrap or Delta method.

Multi-group (dynamical) structural equation models in combination with confirmatory network models from cross-sectional, time-series and panel data <doi:10.31234/osf.io/8ha93>. Allows for confirmatory testing and fit as well as exploratory model search.

Presentation of a new goodness-of-fit normality test based on the Lilliefors method. For details on this method see: Sulewski (2019) <doi:10.1080/03610918.2019.1664580>.

Implementations of algorithms from Learning Sparse Penalties for Change-point Detection using Max Margin Interval Regression, by Hocking, Rigaill, Vert, Bach <http://proceedings.mlr.press/v28/hocking13.html> published in proceedings of ICML2013.

Measures real distances in pictures. With PDM() function, you can choose one *.jpg file, select the measure in mm of scale, starting and and finishing point in the graphical scale, the name of the measure, and starting and and finishing point of the measures. After, ask the user for a new measure.

All PubChem compounds are downloaded to a local computer, but for each compound, only partial records are used. The data are organized into small files referenced by PubChem CID. This package also contains functions to parse the biologically relevant compounds from all PubChem compounds, using biological database sources, pathway presence, and taxonomic relationships. Taxonomy is used to generate a lowest common ancestor taxonomy ID (NCBI) for each biological metabolite, which then enables creation of taxonomically specific metabolome databases for any taxon.

Gives the ability to automatically deploy a plumber API from R functions on DigitalOcean and other cloud-based servers.

In this record linkage package, data preprocessing has been meticulously executed to cover a wide range of datasets, ensuring that variable names are standardized using synonyms. This approach facilitates seamless data integration and analysis across various datasets. While users have the flexibility to modify variable names, the system intelligently ensures that changes are only permitted when they do not compromise data consistency or essential variable essence.

This package provides functions to calculate power and sample size for testing main effect or interaction effect in the survival analysis of epidemiological studies (non-randomized studies), taking into account the correlation between the covariate of the interest and other covariates. Some calculations also take into account the competing risks and stratified analysis. This package also includes a set of functions to calculate power and sample size for testing main effect in the survival analysis of randomized clinical trials and conditional logistic regression for nested case-control study.

Replace the standard print method for functions with one that performs syntax highlighting, using ANSI colors, if the terminal supports them.

Bayesian regularized quantile regression utilizing two major classes of shrinkage priors (the spike-and-slab priors and the horseshoe family of priors) leads to efficient Bayesian shrinkage estimation, variable selection and valid statistical inference. In this package, we have implemented robust Bayesian variable selection with spike-and-slab priors under high-dimensional linear regression models (Fan et al. (2024) <doi:10.3390/e26090794> and Ren et al. (2023) <doi:10.1111/biom.13670>), and regularized quantile varying coefficient models (Zhou et al.(2023) <doi:10.1016/j.csda.2023.107808>). In particular, valid robust Bayesian inferences under both models in the presence of heavy-tailed errors can be validated on finite samples. Additional models with spike-and-slab priors include robust Bayesian group LASSO and robust binary Bayesian LASSO (Fan and Wu (2025) <doi:10.1002/sta4.70078>). Besides, robust sparse Bayesian regression with the horseshoe family of (horseshoe, horseshoe+ and regularized horseshoe) priors has also been implemented and yielded valid inference results under heavy-tailed model errors(Fan et al.(2025) <doi:10.48550/arXiv.2507.10975>). The Markov chain Monte Carlo (MCMC) algorithms of the proposed and alternative models are implemented in C++.

Interactively annotate base R graphics plots with freehand drawing, symbols (points, lines, arrows, rectangles, circles, ellipses), and text. This is useful for teaching, for example to visually explain certain plot elements, and creating quick sketches.

The Penn World Table 8.x provides information on relative levels of income, output, inputs, and productivity for 167 countries between 1950 and 2011.

This package provides functions to perform the peer performance analysis of funds returns as described in Ardia and Boudt (2018) <doi:10.1016/j.jbankfin.2017.10.014>.

This package provides a probabilistic framework that integrates Data Envelopment Analysis (DEA) (Banker et al., 1984) <doi:10.1287/mnsc.30.9.1078> with machine learning classifiers (Kuhn, 2008) <doi:10.18637/jss.v028.i05> to estimate both the (in)efficiency status and the probability of efficiency for decision-making units. The approach trains predictive models on DEA-derived efficiency labels (Charnes et al., 1985) <doi:10.1016/0304-4076(85)90133-2>, enabling explainable artificial intelligence (XAI) workflows with global and local interpretability tools, including permutation importance (Molnar et al., 2018) <doi:10.21105/joss.00786>, Shapley value explanations (Strumbelj & Kononenko, 2014) <doi:10.1007/s10115-013-0679-x>, and sensitivity analysis (Cortez, 2011) <https://CRAN.R-project.org/package=rminer>. The framework also supports probability-threshold peer selection and counterfactual improvement recommendations for benchmarking and policy evaluation. The probabilistic efficiency framework is detailed in González-Moyano et al. (2025) "Probability-based Technical Efficiency Analysis through Machine Learning", in review for publication.

This package provides a collection of utilities and ggplot2 extensions to assist with visualisations in genomic epidemiology. This includes the phylepic chart, a visual combination of a phylogenetic tree and a matched epidemic curve. The included ggplot2 extensions such as date axes binned by week are relevant for other applications in epidemiology and beyond. The approach is described in Suster et al. (2024) <doi:10.1101/2024.04.02.24305229>.

This package provides support for building pkgdown websites without an internet connection. Works by bundling cached dependencies and implementing drop-in replacements for key pkgdown functions. Enables package documentation websites to be built in environments where internet access is unavailable or restricted. For more details on generating pkgdown websites, see Wickham et al. (2025) <doi:10.32614/CRAN.package.pkgdown>.

Analyse prescription drug deliveries to calculate several indicators of polypharmacy corresponding to the various definitions found in the literature. Bjerrum, L., Rosholm, J. U., Hallas, J., & Kragstrup, J. (1997) <doi:10.1007/s002280050329>. Chan, D.-C., Hao, Y.-T., & Wu, S.-C. (2009a) <doi:10.1002/pds.1712>. Fincke, B. G., Snyder, K., Cantillon, C., Gaehde, S., Standring, P., Fiore, L., ... Gagnon, D.R. (2005) <doi:10.1002/pds.966>. Hovstadius, B., Astrand, B., & Petersson, G. (2009) <doi:10.1186/1472-6904-9-11>. Hovstadius, B., Astrand, B., & Petersson, G. (2010) <doi:10.1002/pds.1921>. Kennerfalk, A., Ruigómez, A., Wallander, M.-A., Wilhelmsen, L., & Johansson, S. (2002) <doi:10.1345/aph.1A226>. Masnoon, N., Shakib, S., Kalisch-Ellett, L., & Caughey, G. E. (2017) <doi:10.1186/s12877-017-0621-2>. Narayan, S. W., & Nishtala, P. S. (2015) <doi:10.1007/s40801-015-0020-y>. Nishtala, P. S., & Salahudeen, M. S. (2015) <doi:10.1159/000368191>. Park, H. Y., Ryu, H. N., Shim, M. K., Sohn, H. S., & Kwon, J. W. (2016) <doi:10.5414/cp202484>. Veehof, L., Stewart, R., Haaijer-Ruskamp, F., & Jong, B. M. (2000) <doi:10.1093/fampra/17.3.261>.

This package provides an implementation of a rare variant association test that utilizes protein tertiary structure to increase signal and to identify likely causal variants. Performs structure-guided collapsing, which leads to local tests that borrow information from neighboring variants on a protein and that provide association information on a variant-specific level. For details of the implemented method see West, R. M., Lu, W., Rotroff, D. M., Kuenemann, M., Chang, S-M., Wagner M. J., Buse, J. B., Motsinger-Reif, A., Fourches, D., and Tzeng, J-Y. (2019) <doi:10.1371/journal.pcbi.1006722>.

Data sets for statistical inference modeling related to People Analytics. Contains various data sets from the book Handbook of Regression Modeling in People Analytics by Keith McNulty (2020).

Static code analyses for R packages using the external code-tagging libraries ctags and gtags'. Static analyses enable packages to be analysed very quickly, generally a couple of seconds at most. The package also provides access to a database generating by applying the main function to the full CRAN archive, enabling the statistical properties of any package to be compared with all other CRAN packages.

Utilizes the lme4 and optimx packages (previously the optim() function from stats') to estimate (generalized) linear mixed models (GLMM) with factor structures using a profile likelihood approach, as outlined in Jeon and Rabe-Hesketh (2012) <doi:10.3102/1076998611417628> and Rockwood and Jeon (2019) <doi:10.1080/00273171.2018.1516541>. Factor analysis and item response models can be extended to allow for an arbitrary number of nested and crossed random effects, making it useful for multilevel and cross-classified models.

This package provides general linear model facilities (single y-variable, multiple x-variables with arbitrary mixture of continuous and categorical and arbitrary interactions) for cross-species data. The method is, however, based on the nowadays rather uncommon situation in which uncertainty about a phylogeny is well represented by adopting a single polytomous tree. The theory is in A. Grafen (1989, Proc. R. Soc. B 326, 119-157) and aims to cope with both recognised phylogeny (closely related species tend to be similar) and unrecognised phylogeny (a polytomy usually indicates ignorance about the true sequence of binary splits).

Partial Least Squares Path Modeling (PLS-PM), Tenenhaus, Esposito Vinzi, Chatelin, Lauro (2005) <doi:10.1016/j.csda.2004.03.005>, analysis for both metric and non-metric data, as well as REBUS analysis, Esposito Vinzi, Trinchera, Squillacciotti, and Tenenhaus (2008) <doi:10.1002/asmb.728>.