In gene sequencing methods, the topological features of protein-protein interaction (PPI) networks are often used, such as ToppNet <https://toppgene.cchmc.org>. In this study, a candidate gene prioritization method was proposed for non-communicable diseases considering disease risks transferred between genes in weighted disease PPI networks with weights for nodes and edges based on functional information.

Translates beliefs into prior information in the form of Beta and Gamma distributions. It can be used for the generation of priors on the prevalence of disease and the sensitivity/specificity of diagnostic tests and any other binomial experiment.

This package implements novel tools for estimating sample sizes needed for phylogenetic studies, including studies focused on estimating the probability of true pathogen transmission between two cases given phylogenetic linkage and studies focused on tracking pathogen variants at a population level. Methods described in Wohl, Giles, and Lessler (2021) and in Wohl, Lee, DiPrete, and Lessler (2023).

Several person-fit statistics (PFSs; Meijer and Sijtsma, 2001, <doi:10.1177/01466210122031957>) are offered. These statistics allow assessing whether individual response patterns to tests or questionnaires are (im)plausible given the other respondents in the sample or given a specified item response theory model. Some PFSs apply to dichotomous data, such as the likelihood-based PFSs (lz, lz*) and the group-based PFSs (personal biserial correlation, caution index, (normed) number of Guttman errors, agreement/disagreement/dependability statistics, U3, ZU3, NCI, Ht). PFSs suitable to polytomous data include extensions of lz, U3, and (normed) number of Guttman errors.

An implementation of Bayesian single-arm phase II design methods for binary outcome based on posterior probability (Thall and Simon (1994) <doi:10.2307/2533377>) and predictive probability (Lee and Liu (2008) <doi:10.1177/1740774508089279>).

This work is an extension of the state space model for Poisson count data, Poisson-Gamma model, towards a semiparametric specification. Just like the generalized additive models (GAM), cubic splines are used for covariate smoothing. The semiparametric models are fitted by an iterative process that combines maximization of likelihood and backfitting algorithm.

This package provides a set of tools to implement the non-parametric bounds and Bayesian methods for assessing post-treatment bias developed in Blackwell, Brown, Hill, Imai, and Yamamoto (2025) <doi:10.1017/pan.2025.3>.

Model-implied simulation-based power estimation (MSPE) for nonlinear (and linear) SEM, path analysis and regression analysis. A theoretical framework is used to approximate the relation between power and sample size for given type I error rates and effect sizes. The package offers an adaptive search algorithm to find the optimal N for given effect sizes and type I error rates. Plots can be used to visualize the power relation to N for different parameters of interest (POI). Theoretical justifications are given in Irmer et al. (2024a) <doi:10.31219/osf.io/pe5bj> and detailed description are given in Irmer et al. (2024b) <doi:10.3758/s13428-024-02476-3>.

An implementation of data analysis tools for samples of symmetric or Hermitian positive definite matrices, such as collections of covariance matrices or spectral density matrices. The tools in this package can be used to perform: (i) intrinsic wavelet transforms for curves (1D) or surfaces (2D) of Hermitian positive definite matrices with applications to dimension reduction, denoising and clustering in the space of Hermitian positive definite matrices; and (ii) exploratory data analysis and inference for samples of positive definite matrices by means of intrinsic data depth functions and rank-based hypothesis tests in the space of Hermitian positive definite matrices.

An interface to the API for Pan-STARRS1', a data archive of the PS1 wide-field astronomical survey. The package allows access to the PS1 catalog and to the PS1 images. (see <https://outerspace.stsci.edu/display/PANSTARRS/> for more information). You can use it to plan astronomical observations, make guidance pictures, find magnitudes in five broadband filters (g, r, i, z, y) and more.

This package provides a wrapper around the generic coordinate transformation software PROJ that transforms coordinates from one coordinate reference system ('CRS') to another. This includes cartographic projections as well as geodetic transformations. The intention is for this package to be used by user-packages such as reproj', and that the older PROJ.4 and version 5 pathways be provided by the proj4 package.

This package provides additional functions for evaluating predictive models, including plotting calibration curves and model-based Receiver Operating Characteristic (mROC) based on Sadatsafavi et al (2021) <arXiv:2003.00316>.

Different regularization approaches for Cox Frailty Models by penalization methods are provided. see Groll et al. (2017) <doi:10.1111/biom.12637> for effects selection. See also Groll and Hohberg (2024) <doi:10.1002/bimj.202300020> for classical LASSO approach.

This package provides data set and function for exploration of Multiple Indicator Cluster Survey (MICS) 2017-18 Household questionnaire data for Punjab, Pakistan. The results of the present survey are critically important for the purposes of Sustainable Development Goals (SDGs) monitoring, as the survey produces information on 32 global Sustainable Development Goals (SDGs) indicators. The data was collected from 53,840 households selected at the second stage with systematic random sampling out of a sample of 2,692 clusters selected using probability proportional to size sampling. Six questionnaires were used in the survey: (1) a household questionnaire to collect basic demographic information on all de jure household members (usual residents), the household, and the dwelling; (2) a water quality testing questionnaire administered in three households in each cluster of the sample; (3) a questionnaire for individual women administered in each household to all women age 15-49 years; (4) a questionnaire for individual men administered in every second household to all men age 15-49 years; (5) an under-5 questionnaire, administered to mothers (or caretakers) of all children under 5 living in the household; and (6) a questionnaire for children age 5-17 years, administered to the mother (or caretaker) of one randomly selected child age 5-17 years living in the household (<http://www.mics.unicef.org/surveys>).

Spatial estimation of a prevalence surface or a relative risks surface, using data from a Demographic and Health Survey (DHS) or an analog survey, see Larmarange et al. (2011) <doi:10.4000/cybergeo.24606>.

The perturbR() function incrementally perturbs network edges (using the rewireR function)and compares the resulting community detection solutions from the rewired networks with the solution found for the original network. These comparisons aid in understanding the stability of the original solution. The package requires symmetric, weighted (specifically, count) matrices/networks.

This package provides a suite of functions that fit models that use PPM type priors for partitions. Models include hierarchical Gaussian and probit ordinal models with a (covariate dependent) PPM. If a covariate dependent product partition model is selected, then all the options detailed in Page, G.L.; Quintana, F.A. (2018) <doi:10.1007/s11222-017-9777-z> are available. If covariate values are missing, then the approach detailed in Page, G.L.; Quintana, F.A.; Mueller, P (2020) <doi:10.1080/10618600.2021.1999824> is employed. Also included in the package is a function that fits a Gaussian likelihood spatial product partition model that is detailed in Page, G.L.; Quintana, F.A. (2016) <doi:10.1214/15-BA971>, and multivariate PPM change point models that are detailed in Quinlan, J.J.; Page, G.L.; Castro, L.M. (2023) <doi:10.1214/22-BA1344>. In addition, a function that fits a univariate or bivariate functional data model that employs a PPM or a PPMx to cluster curves based on B-spline coefficients is provided.

Prepares data for statistical analysis (e.g., analysis of variance ;ANOVA) by enabling the user to easily and quickly merge (using the file_merge() function) raw data files into one merged table and then aggregate the merged table (using the prep() function) into a finalized table while keeping track and summarizing every step of the preparation. The finalized table contains several possibilities for dependent measures of the dependent variable. Most suitable when measuring variables in an interval or ratio scale (e.g., reaction-times) and/or discrete values such as accuracy. Main functions included are file_merge() and prep(). The file_merge() function vertically merges individual data files (in a long format) in which each line is a single observation to one single dataset. The prep() function aggregates the single dataset according to any combination of grouping variables (i.e., between-subjects and within-subjects independent variables, respectively), and returns a data frame with a number of dependent measures for further analysis for each cell according to the combination of provided grouping variables. Dependent measures for each cell include among others means before and after rejecting all values according to a flexible standard deviation criteria, number of rejected values according to the flexible standard deviation criteria, proportions of rejected values according to the flexible standard deviation criteria, number of values before rejection, means after rejecting values according to procedures described in Van Selst & Jolicoeur (1994; suitable when measuring reaction-times), standard deviations, medians, means according to any percentile (e.g., 0.05, 0.25, 0.75, 0.95) and harmonic means. The data frame prep() returns can also be exported as a txt file to be used for statistical analysis in other statistical programs.

Perform scale linking to establish relationships between instruments that measure similar constructs according to the PROsetta Stone methodology, as in Choi, Schalet, Cook, & Cella (2014) <doi:10.1037/a0035768>.

This package provides functions to access data from public RESTful APIs including Nager.Date', World Bank API', and REST Countries API', retrieving real-time or historical data related to Peru, such as holidays, economic indicators, and international demographic and geopolitical indicators. Additionally, the package includes curated datasets focused on Peru, covering topics such as administrative divisions, electoral data, demographics, biodiversity and educational classifications. The package supports reproducible research and teaching by integrating reliable international APIs and structured datasets from public, academic, and government sources. For more information on the APIs, see: Nager.Date <https://date.nager.at/Api>, World Bank API <https://datahelpdesk.worldbank.org/knowledgebase/articles/889392>, and REST Countries API <https://restcountries.com/>.

Estimation of two- and three-way dynamic panel threshold regression models (Di Lascio and Perazzini (2024) <https://repec.unibz.it/bemps104.pdf>; Di Lascio and Perazzini (2022, ISBN:978-88-9193-231-0); Seo and Shin (2016) <doi:10.1016/j.jeconom.2016.03.005>) through the generalized method of moments based on the first difference transformation and the use of instrumental variables. The models can be used to find a change point detection in the time series. In addition, random number generation is also implemented.

Supports propensity score weighting analysis of observational studies and randomized trials. Enables the estimation and inference of average causal effects with binary and multiple treatments using overlap weights (ATO), inverse probability of treatment weights (ATE), average treatment effect among the treated weights (ATT), matching weights (ATM) and entropy weights (ATEN), with and without propensity score trimming. These weights are members of the family of balancing weights introduced in Li, Morgan and Zaslavsky (2018) <doi:10.1080/01621459.2016.1260466> and Li and Li (2019) <doi:10.1214/19-AOAS1282>.

Text mining of PubMed Abstracts (text and XML) from <https://pubmed.ncbi.nlm.nih.gov/>.

This package provides path_chain class and functions, which facilitates loading and saving directory structure in YAML configuration files via config package. The file structure you created during exploration can be transformed into legible section in the config file, and then easily loaded for further usage.