Using a Bayesian estimation procedure, this package fits linear quantile regression models such as linear quantile models, linear quantile mixed models, quantile regression joint models for time-to-event and longitudinal data. The estimation procedure is based on the asymmetric Laplace distribution and the JAGS software is used to get posterior samples (Yang, Luo, DeSantis (2019) <doi:10.1177/0962280218784757>).

An interactive document on the topic of binary logistic regression analysis using rmarkdown and shiny packages. Runtime examples are provided in the package function as well as at <https://analyticmodels.shinyapps.io/BinaryLogisticRegressionModelling/>.

This package implements Bayesian brain mapping models, including the prior ICA (independent components analysis) model proposed in Mejia et al. (2020) <doi:10.1080/01621459.2019.1679638> and the spatial prior ICA model proposed in proposed in Mejia et al. (2022) <doi:10.1080/10618600.2022.2104289>. Both models estimate subject-level brain as deviations from known population-level networks, which are estimated using standard ICA algorithms. Both models employ an expectation-maximization algorithm for estimation of the latent brain networks and unknown model parameters. Includes direct support for CIFTI', GIFTI', and NIFTI neuroimaging file formats.

Simulation, estimation and forecasting of first-order Beta-Skew-t-EGARCH models with leverage (one-component, two-component, skewed versions).

This package provides methods for estimating the area under the concentration versus time curve (AUC) and its standard error in the presence of Below the Limit of Quantification (BLOQ) observations. Two approaches are implemented: direct estimation using censored maximum likelihood, and a two-step approach that first imputes BLOQ values using various methods and then computes the AUC using the imputed data. Technical details are described in Barnett et al. (2020), "Methods for Non-Compartmental Pharmacokinetic Analysis With Observations Below the Limit of Quantification," Statistics in Biopharmaceutical Research. <doi:10.1080/19466315.2019.1701546>.

MDS is a statistic tool for reduction of dimensionality, using as input a distance matrix of dimensions n à n. When n is large, classical algorithms suffer from computational problems and MDS configuration can not be obtained. With this package, we address these problems by means of six algorithms, being two of them original proposals: - Landmark MDS proposed by De Silva V. and JB. Tenenbaum (2004). - Interpolation MDS proposed by Delicado P. and C. Pachón-Garcà a (2021) <arXiv:2007.11919> (original proposal). - Reduced MDS proposed by Paradis E (2018). - Pivot MDS proposed by Brandes U. and C. Pich (2007) - Divide-and-conquer MDS proposed by Delicado P. and C. Pachón-Garcà a (2021) <arXiv:2007.11919> (original proposal). - Fast MDS, proposed by Yang, T., J. Liu, L. McMillan and W. Wang (2006).

Fetches zonal statistics from weather indicators that were calculated for each municipality in Brazil using data from the BR-DWGD and TerraClimate projects. Zonal statistics such as mean, maximum, minimum, standard deviation, and sum were computed by taking into account the data cells that intersect the boundaries of each municipality and stored in Parquet files. This procedure was carried out for all Brazilian municipalities, and for all available dates, for every indicator available in the weather products (BR-DWGD and TerraClimate projects). This package queries on-line the already calculated statistics on the Parquet files and returns easy-to-use data.frames.

This package implements the EM algorithm with one-step Gradient Descent method to estimate the parameters of the Block-Basu bivariate Pareto distribution with location and scale. We also found parametric bootstrap and asymptotic confidence intervals based on the observed Fisher information of scale and shape parameters, and exact confidence intervals for location parameters. Details are in Biplab Paul and Arabin Kumar Dey (2023) <doi:10.48550/arXiv.1608.02199> "An EM algorithm for absolutely continuous Marshall-Olkin bivariate Pareto distribution with location and scale"; E L Lehmann and George Casella (1998) <doi:10.1007/b98854> "Theory of Point Estimation"; Bradley Efron and R J Tibshirani (1994) <doi:10.1201/9780429246593> "An Introduction to the Bootstrap"; A P Dempster, N M Laird and D B Rubin (1977) <www.jstor.org/stable/2984875> "Maximum Likelihood from Incomplete Data via the EM Algorithm".

Get z-scores, percentiles, absolute values, and percent of predicted of a reference cohort. Functionality requires installing the data packages adiposerefdata and musclerefdata'. For more information on the underlying research, please visit our website which also includes a graphical interface. The models and underlying data are described in Marquardt JP et al.(planned publication 2025; reserved doi 10.1097/RLI.0000000000001104), "Subcutaneous and Visceral adipose tissue Reference Values from Framingham Heart Study Thoracic and Abdominal CT", *Investigative Radiology* and Tonnesen PE et al. (2023), "Muscle Reference Values from Thoracic and Abdominal CT for Sarcopenia Assessment [column] The Framingham Heart Study", *Investigative Radiology*, <doi:10.1097/RLI.0000000000001012>.

Shows statistics about bytes contained in a file as a circle graph of deviations from mean in sigma increments. The function can be useful for statistically analyze the content of files in a glimpse: text files are shown as a green centered crown, compressed and encrypted files should be shown as equally distributed variations with a very low CV (sigma/mean), and other types of files can be classified between these two categories depending on their text vs binary content, which can be useful to quickly determine how information is stored inside them (databases, multimedia files, etc).

Algorithms developed for binned data analysis, gene expression data analysis and measurement error models for ordinal data analysis.

The BioTIME database was first published in 2018 and inspired ideas, questions, project and research article. To make it even more accessible, an R package was created. The BioTIMEr package provides tools designed to interact with the BioTIME database. The functions provided include the BioTIME recommended methods for preparing (gridding and rarefaction) time series data, a selection of standard biodiversity metrics (including species richness, numerical abundance and exponential Shannon) alongside examples on how to display change over time. It also includes a sample subset of both the query and meta data, the full versions of which are freely available on the BioTIME website <https://biotime.st-andrews.ac.uk/home.php>.

This package provides tools to fit Bayesian state-space models to animal tracking data. Models are provided for location filtering, location filtering and behavioural state estimation, and their hierarchical versions. The models are primarily intended for fitting to ARGOS satellite tracking data but options exist to fit to other tracking data types. For Global Positioning System data, consider the moveHMM package. Simplified Markov Chain Monte Carlo convergence diagnostic plotting is provided but users are encouraged to explore tools available in packages such as coda and boa'.

Prognostic Enrichment is a strategy of enriching a clinical trial for testing an intervention intended to prevent or delay an unwanted clinical event. A prognostically enriched trial enrolls only patients who are more likely to experience the unwanted clinical event than the broader patient population (R. Temple (2010) <doi:10.1038/clpt.2010.233>). By testing the intervention in an enriched study population, the trial may be adequately powered with a smaller sample size, which can have both practical and ethical advantages. This package provides tools to evaluate biomarkers for prognostic enrichment of clinical trials with survival/time-to-event outcomes.

This package provides functions to implement a Hwang(2021) <doi:10.2139/ssrn.3866876> estimator, which bounds an omitted variable bias using auxiliary data.

Calculate the operating characteristics of the Bayesian Optimal Interval with Back Filling Design for dose escalation in early-phase oncology trials.

Survey systems and other third-party data sources commonly use non-standard representations of logical values when it comes to qualitative data - "Yes", "No" and "N/A", say. batman is a package designed to seamlessly convert these into logicals. It is highly localised, and contains equivalents to boolean values in languages including German, French, Spanish, Italian, Turkish, Chinese and Polish.

Model-based clustering using Bayesian parsimonious Gaussian mixture models. MCMC (Markov chain Monte Carlo) are used for parameter estimation. The RJMCMC (Reversible-jump Markov chain Monte Carlo) is used for model selection. GREEN et al. (1995) <doi:10.1093/biomet/82.4.711>.

All the seeds do not germinate at a single point in time due to physiological mechanisms determined by temperature which vary among individual seeds in the population. Seeds germinate by following accumulation of thermal time in degree days/hours, quantified by multiplying the time of germination with excess of base temperature required by each seed for its germination, which follows log-normal distribution. The theoretical germination course can be obtained by regressing the rate of germination at various fractions against temperature (Garcia et al., 1982), where the fraction-wise regression lines intersect the temperature axis at base temperature and the methodology of determining optimum base temperature has been described by Ellis et al. (1987). This package helps to find the base temperature of seed germination using algorithms of Garcia et al. (1982) and Ellis et al. (1982) <doi:10.1093/JXB/38.6.1033> <doi:10.1093/jxb/33.2.288>.

This package implements a bootstrap-based heterogeneity test for standardized mean differences (d), Fisher-transformed Pearson's correlations (r), and natural-logarithm-transformed odds ratio (or) in meta-analysis studies. Depending on the presence of moderators, this Monte Carlo based test can be implemented in the random- or mixed-effects model. This package uses rma() function from the R package metafor to obtain parameter estimates and likelihoods, so installation of R package metafor is required. This approach refers to the studies of Anscombe (1956) <doi:10.2307/2332926>, Haldane (1940) <doi:10.2307/2332614>, Hedges (1981) <doi:10.3102/10769986006002107>, Hedges & Olkin (1985, ISBN:978-0123363800), Silagy, Lancaster, Stead, Mant, & Fowler (2004) <doi:10.1002/14651858.CD000146.pub2>, Viechtbauer (2010) <doi:10.18637/jss.v036.i03>, and Zuckerman (1994, ISBN:978-0521432009).

Simulate, estimate and forecast a wide range of regression based dynamic models for bounded time series, covering the most commonly applied models in the literature. The main calculations are done in FORTRAN, which translates into very fast algorithms.

Bayesian Latent Class Analysis using several different methods.

Finite Population bootstrap algorithms to estimate the variance of the Horvitz-Thompson estimator for single-stage sampling. For a survey of bootstrap methods for finite populations, see Mashreghi et Al. (2016) <doi:10.1214/16-SS113>.

The backfill Bayesian optimal interval design using efficacy and toxicity outcomes for dose optimization (BF-BOIN-ET) design is a novel clinical trial design to allow patients to be backfilled at lower doses during a dose-finding trial while prioritizing the dose-escalation cohort to explore a higher dose. The advantages compared to the other designs in terms of the percentage of correct optimal dose (OD) selection, reducing the sample size, and shortening the duration of the trial, in various realistic setting.