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Useful functions and workflows for proteomics quality control and data analysis of both limited proteolysis-coupled mass spectrometry (LiP-MS) (Feng et. al. (2014) <doi:10.1038/nbt.2999>) and regular bottom-up proteomics experiments. Data generated with search tools such as Spectronaut', MaxQuant and Proteome Discover can be easily used due to flexibility of functions.
Finds equivalence classes corresponding to a symmetric relation or undirected graph. Finds total order consistent with partial order or directed graph (so-called topological sort).
Proteins reside in either the cell plasma or in the cell membrane. A membrane protein goes through the membrane at least once. Given the amino acid sequence of a membrane protein, the tool PureseqTM (<https://github.com/PureseqTM/pureseqTM_package>, as described in "Efficient And Accurate Prediction Of Transmembrane Topology From Amino acid sequence only.", Wang, Qing, et al (2019), <doi:10.1101/627307>), can predict the topology of a membrane protein. This package allows one to use PureseqTM from R.
Plot both fixed and random effects of linear mixed models, multilevel models in a single spaghetti plot. The package allows to visualize the effect of a predictor on a criterion between different levels of a grouping variable. Additionally, confidence intervals can be displayed for fixed effects. Calculation of predicted values of random effects allows only models with one random intercept and/or one random slope to be plotted. Confidence intervals and predicted values of fixed effects are computed using the ggpredict function from the ggeffects package. Lüdecke, D. (2018) <doi:10.21105/joss.00638>.
This package provides an object type and associated tools for storing and wrangling panel data. Implements several methods for creating regression models that take advantage of the unique aspects of panel data. Among other capabilities, automates the "within-between" (also known as "between-within" and "hybrid") panel regression specification that combines the desirable aspects of both fixed effects and random effects econometric models and fits them as multilevel models (Allison, 2009 <doi:10.4135/9781412993869.d33>; Bell & Jones, 2015 <doi:10.1017/psrm.2014.7>). These models can also be estimated via generalized estimating equations (GEE; McNeish, 2019 <doi:10.1080/00273171.2019.1602504>) and Bayesian estimation is (optionally) supported via Stan'. Supports estimation of asymmetric effects models via first differences (Allison, 2019 <doi:10.1177/2378023119826441>) as well as a generalized linear model extension thereof using GEE.
Statistical power simulation for testing the Rasch Model based on a three-way analysis of variance design with mixed classification.
Permutation based Kolmogorov-Smirnov test for paired samples. The test was proposed by Wang W.S., Amsler C. and Schmidt, P. (2025) <doi:10.1007/s00181-025-02779-0>.
This package provides data set and function for exploration of Multiple Indicator Cluster Survey (MICS) 2017-18 Household questionnaire data for Punjab, Pakistan. The results of the present survey are critically important for the purposes of Sustainable Development Goals (SDGs) monitoring, as the survey produces information on 32 global Sustainable Development Goals (SDGs) indicators. The data was collected from 53,840 households selected at the second stage with systematic random sampling out of a sample of 2,692 clusters selected using probability proportional to size sampling. Six questionnaires were used in the survey: (1) a household questionnaire to collect basic demographic information on all de jure household members (usual residents), the household, and the dwelling; (2) a water quality testing questionnaire administered in three households in each cluster of the sample; (3) a questionnaire for individual women administered in each household to all women age 15-49 years; (4) a questionnaire for individual men administered in every second household to all men age 15-49 years; (5) an under-5 questionnaire, administered to mothers (or caretakers) of all children under 5 living in the household; and (6) a questionnaire for children age 5-17 years, administered to the mother (or caretaker) of one randomly selected child age 5-17 years living in the household (<http://www.mics.unicef.org/surveys>).
Useful set of tools for plotting network diagrams in any kind of project.
Identifies the entries with patterned responses for psychometric scales. The patterns included in the package are identical (a, a, a), ascending (a, b, c), descending (c, b, a), alternative (a, b, a, b / a, b, c, a, b, c).
An open-source toolbox for storing, validating, managing, and exploring transportation infrastructure data. Provides a relational data model for binders, aggregates, mixtures, and test results, with a human-readable file format (.pavdata) aligned with FAIR principles.
Deploy, maintain, and invoke predictive models using the Alteryx Promote REST API. Alteryx Promote is available at the URL: <https://www.alteryx.com/products/alteryx-promote>.
Permutation (randomisation) test for single-case phase design data with two phases (e.g., pre- and post-treatment). Correction for dependency of observations is done through stepwise resampling the time series while varying the distance between observations. The required distance 0,1,2,3.. is determined based on repeated dependency testing while stepwise increasing the distance. In preparation: Vroegindeweij et al. "A Permutation distancing test for single-case observational AB phase design data: A Monte Carlo simulation study".
Recursive construction of balanced incomplete block designs (BIBDs), their successive generations, resolvable BIBDs (RBIBDs) and associated uniform designs (UDs), derived from finite projective geometries PG(m, p) over a Galois field GF(p) of any prime order p. Implements and generalises the method of Boudraa, Gheribi-Aoulmi and Laib (2013, International Journal of Research and Reviews in Applied Sciences, 17(2), 167-176), which was previously available only for p = 2, and the uniform design constructions of Fang et al. (2004) <doi:10.1016/S0012-365X(03)00100-6>. Designs of every recursion stage can be extracted, and all constructions are validated against the parameters published in the original paper.
Simulate and run the Gaussian puff forward atmospheric model in sensor (specific sensor coordinates) or grid (across the grid of a full oil and gas operations site) modes, following Jia, M., Fish, R., Daniels, W., Sprinkle, B. and Hammerling, D. (2024) <doi:10.26434/chemrxiv-2023-hc95q-v3>. Numerous visualization options, including static and animated, 2D and 3D, and a site map generator based on sensor and source coordinates.
This package provides a set of Analysis Data Model (ADaM) datasets constructed by modifying the ADaM datasets in the pharmaverseadam package to meet J&J Innovative Medicine's standard data structure for Clinical and Statistical Programming.
Bayesian estimation and analysis methods for Probit Unfolding Models (PUMs), a novel class of scaling models designed for binary preference data. These models allow for both monotonic and non-monotonic response functions. The package supports Bayesian inference for both static and dynamic PUMs using Markov chain Monte Carlo (MCMC) algorithms with minimal or no tuning. Key functionalities include posterior sampling, hyperparameter selection, data preprocessing, model fit evaluation, and visualization. The methods are particularly suited to analyzing voting data, such as from the U.S. Congress or Supreme Court, but can also be applied in other contexts where non-monotonic responses are expected. For methodological details, see Shi et al. (2025) <doi:10.48550/arXiv.2504.00423>.
This package provides a tool, grammar, and standard to represent and exchange R package source code as text files. Converts one or more source packages to a text file and restores the package structures from the file.
This package implements Progressive Regularized Vine Copula (Prog-Vine) frameworks for high-dimensional dependent competing risks with masked failure causes under Progressive Type-II Censoring. Fits Weibull marginals, estimates pair-copula trees using Expectation-Maximization (EM) algorithms, computes Louis observed information confidence intervals, and implements Data Augmentation Gibbs Samplers for Bayesian credible intervals.
Send requests to the PurpleAir Application Programming Interface (API; <https://community.purpleair.com/c/data/api/18>). Check a PurpleAir API key and get information about the related organization. Download real-time data from a single PurpleAir sensor or many sensors by sensor identifier, geographical bounding box, or time since modified. Download historical data from a single sensor. Stream real time data from monitors on a local area network.
Routines for flexible functional form estimation via basis regression, with model selection via the adaptive LASSO or SCAD to prevent overfitting.
Allows the comparison of data cohorts (DC) against a Counter Factual Model (CFM) and measures the difference in terms of an efficacy parameter. Allows the application of Personalised Synthetic Controls.
Validation of risk predictions obtained from survival models and competing risk models based on censored data using inverse weighting and cross-validation. Most of the pec functionality has been moved to riskRegression'.
This package provides a set of palettes imported from Gimp distributed under GPL3 (<https://www.gimp.org/about/COPYING>), and Inkscape distributed under GPL2 (<https://inkscape.org/about/license/>).