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Simultaneously clusters the Periodontal diseases (PD) patients and their tooth sites after taking the patient- and site-level covariates into consideration. BAREB uses the determinantal point process (DPP) prior to induce diversity among different biclusters to facilitate parsimony and interpretability. Essentially, BAREB is a cluster-wise linear model based on Yuliang (2020) <doi:10.1002/sim.8536>.
Biologically Explainable Machine Learning Framework for Phenotype Prediction using omics data described in Chen and Schwarz (2017) <doi:10.48550/arXiv.1712.00336>.Identifying reproducible and interpretable biological patterns from high-dimensional omics data is a critical factor in understanding the risk mechanism of complex disease. As such, explainable machine learning can offer biological insight in addition to personalized risk scoring.In this process, a feature space of biological pathways will be generated, and the feature space can also be subsequently analyzed using WGCNA (Described in Horvath and Zhang (2005) <doi:10.2202/1544-6115.1128> and Langfelder and Horvath (2008) <doi:10.1186/1471-2105-9-559> ) methods.
The goal of BayesPower is to provide tools for Bayesian sample size determination and power analysis across a range of common hypothesis testing scenarios using Bayes factors. The main function, BayesPower_BayesFactor(), launches an interactive shiny application for performing these analyses. The application also provides command-line code for reproducibility. Details of the methods are described in the tutorial by Wong, Pawel, and Tendeiro (2025) <doi:10.31234/osf.io/pgdac_v1>.
This package implements z-test, t-test, and normal moment prior Bayes factors based on summary statistics, along with functionality to perform corresponding power and sample size calculations as described in Pawel and Held (2025) <doi:10.1080/00031305.2025.2467919>.
R bindings for the various functions and statistical distributions provided by the Boost Math library <https://www.boost.org/doc/libs/latest/libs/math/doc/html/index.html>.
BEAST2 (<https://www.beast2.org>) is a widely used Bayesian phylogenetic tool, that uses DNA/RNA/protein data and many model priors to create a posterior of jointly estimated phylogenies and parameters. BEAUti 2 (which is part of BEAST2') is a GUI tool that allows users to specify the many possible setups and generates the XML file BEAST2 needs to run. This package provides a way to create BEAST2 input files without active user input, but using R function calls instead.
This package implements bidirectional two-stage least squares (Bi-TSLS) estimation for identifying bidirectional causal effects between two variables in the presence of unmeasured confounding. The method uses proxy variables (negative control exposure and outcome) along with at least one covariate to handle confounding.
This package provides functions for summarizing and plotting the output of the command-line tool BeXY (<https://bitbucket.org/wegmannlab/bexy>), a tool that performs Bayesian inference of sex chromosome karyotypes and sex-linked scaffolds from low-depth sequencing data.
Analyze and plot the abundance of different RNA biotypes present in a count matrix, this evaluation can be useful if you want to test different strategies of normalization or analyze a particular biotype in a differential gene expression analysis.
Data sets and functions for chi-squared Hardy-Weinberg and case-control association tests of highly polymorphic genetic data [e.g., human leukocyte antigen (HLA) data]. Performs association tests at multiple levels of polymorphism (haplotype, locus and HLA amino-acids) as described in Pappas DJ, Marin W, Hollenbach JA, Mack SJ (2016) <doi:10.1016/j.humimm.2015.12.006>. Combines rare variants to a common class to account for sparse cells in tables as described by Hollenbach JA, Mack SJ, Thomson G, Gourraud PA (2012) <doi:10.1007/978-1-61779-842-9_14>.
Bayesian dynamic borrowing with covariate adjustment via inverse probability weighting for simulations and data analyses in clinical trials. This makes it easy to use propensity score methods to balance covariate distributions between external and internal data. This methodology based on Psioda et al (2025) <doi:10.1080/10543406.2025.2489285>.
This package provides functions to compute the asymptotic covariance matrices of mixing and unmixing matrix estimates of the following blind source separation (BSS) methods: symmetric and squared symmetric FastICA, regular and adaptive deflation-based FastICA, FOBI, JADE, AMUSE and deflation-based and symmetric SOBI. Also functions to estimate these covariances based on data are available.
This package provides significance tests for second-order stationarity for time series using bootstrap wavelet packet tests. Provides functionality to visualize the time series with the results of the hypothesis tests superimposed. The methodology is described in Cardinali, A and Nason, G P (2016) "Practical powerful wavelet packet tests for second-order stationarity." Applied and Computational Harmonic Analysis, 44, 558-585 <doi:10.1016/j.acha.2016.06.006>.
Assume that a temporal process is composed of contiguous segments with differing slopes and replicated noise-corrupted time series measurements are observed. The unknown mean of the data generating process is modelled as a piecewise linear function of time with an unknown number of change-points. The package infers the joint posterior distribution of the number and position of change-points as well as the unknown mean parameters per time-series by MCMC sampling. A-priori, the proposed model uses an overfitting number of mean parameters but, conditionally on a set of change-points, only a subset of them influences the likelihood. An exponentially decreasing prior distribution on the number of change-points gives rise to a posterior distribution concentrating on sparse representations of the underlying sequence, but also available is the Poisson distribution. See Papastamoulis et al (2019) <doi:10.1515/ijb-2018-0052> for a detailed presentation of the method.
This package provides tools to read, write, parse, and analyze forest fire history data (e.g. FHX). Described in Malevich et al. (2018) <doi:10.1016/j.dendro.2018.02.005>.
Fits a piecewise exponential hazard to survival data using a Hierarchical Bayesian model with an Intrinsic Conditional Autoregressive formulation for the spatial dependency in the hazard rates for each piece. This function uses Metropolis- Hastings-Green MCMC to allow the number of split points to vary and also uses Stochastic Search Variable Selection to determine what covariates drive the risk of the event. This function outputs trace plots depicting the number of split points in the hazard and the number of variables included in the hazard. The function saves all posterior quantities to the desired path.
This package provides a Bayesian framework to estimate the Student's t-distribution's degrees of freedom is developed. Markov Chain Monte Carlo sampling routines are developed as in <doi:10.3390/axioms11090462> to sample from the posterior distribution of the degrees of freedom. A random walk Metropolis algorithm is used for sampling when Jeffrey's and Gamma priors are endowed upon the degrees of freedom. In addition, the Metropolis-adjusted Langevin algorithm for sampling is used under the Jeffrey's prior specification. The Log-normal prior over the degrees of freedom is posed as a viable choice with comparable performance in simulations and real-data application, against other prior choices, where an Elliptical Slice Sampler is used to sample from the concerned posterior.
Battery reduction is a method used in data reduction. It uses Gram-Schmidt orthogonal rotations to find out a subset of variables best representing the original set of variables.
This package provides tools to facilitate the access and processing of data from the Central Bank of Brazil API. The package allows users to retrieve economic and financial data, transforming them into usable tabular formats for further analysis. The data is obtained from the Central Bank of Brazil API: <https://api.bcb.gov.br/dados/serie/bcdata.sgs.series_code/dados?formato=json&dataInicial=start_date&dataFinal=end_date>.
Bayesian inference on the (discrete) power spectrum of time series.
This package provides tools designed to make it easier for beginner and intermediate users to build and validate binary logistic regression models. Includes bivariate analysis, comprehensive regression output, model fit statistics, variable selection procedures, model validation techniques and a shiny app for interactive model building.
Build decision trees and random forests for classification and regression. The implementation strikes a balance between minimizing computing efforts and maximizing the expected predictive accuracy, thus scales well to large data sets. Multi-threading is available through OpenMP <https://gcc.gnu.org/wiki/openmp>.
This package implements Bayesian spatio-temporal factor analysis models for multivariate data observed across space and time. The package provides tools for model fitting via Markov chain Monte Carlo (MCMC), spatial and temporal interpolation, and visualization of latent factors and loadings to support inference and exploration of underlying spatio-temporal patterns. Designed for use in environmental, ecological, or public health applications, with support for posterior prediction and uncertainty quantification. Includes functions such as BSTFA() for model fitting and plot_factor() to visualize the latent processes. Functions are based on and extended from methods described in Berrett, et al. (2020) <doi:10.1002/env.2609>.
This package implements the Bayesian paradigm for fractional polynomial models under the assumption of normally distributed error terms, see Sabanes Bove, D. and Held, L. (2011) <doi:10.1007/s11222-010-9170-7>.