Draws circular and linear plasmid maps with grid graphics. Features are shown as colored arcs with optional arrowheads, callout labels that are laid out to avoid overlap, an automatic base-pair scale, and the plasmid name and size. A style is built from a handful of shape parameters, with presets as named combinations of them, and the layout follows the molecule's topology. Maps can be built up feature by feature or imported from GenBank', EMBL', FASTA and SnapGene files, whose format is detected from content rather than file extension. Restriction sites can be located in the sequence and labeled. Ships eight visual styles, including one inspired by the AngularPlasmid JavaScript library, and seven categorical palettes checked for colorblind safety. Palettes from other packages can be used directly, as a color vector or as a palette function, and checked against the same criteria.

Send push notifications to mobile devices or the desktop using Pushover <https://pushover.net>. These notifications can display things such as results, job status, plots, or any other text or numeric data.

This package provides tools for calculating statistical power for experiments analyzed using linear mixed models. It supports standard designs, including randomized block, split-plot, and Latin Square designs, while offering flexibility to accommodate a variety of other complex study designs.

Simple method of purging independent variables of mediating effects. First, regress the direct variable on the indirect variable. Then, used the stored residuals as the new purged (direct) variable in the updated specification. This purging process allows for use of a new direct variable uncorrelated with the indirect variable. Please cite the method and/or package using Waggoner, Philip D. (2018) <doi:10.1177/1532673X18759644>.

Generates sequential, diverging and categorical colour palettes from a single seed colour in OKLCH (the cylindrical lightness-chroma-hue representation of the Oklab perceptual colour space), with spacing measured by the CIEDE2000 colour-difference formula of the International Commission on Illumination. Audits every palette under simulated colour-vision deficiency, greyscale conversion, the standard Red Green Blue (sRGB) gamut and Web Content Accessibility Guidelines (WCAG) contrast. Colour-vision deficiency is simulated at severity 1.0 with the model of Machado, Oliveira and Fernandes (2009) <doi:10.1109/TVCG.2009.113>; the design rationale follows Crameri, Shephard and Heron (2020) <doi:10.1038/s41467-020-19160-7>. Mirrors the Python reference implementation maintained in the same repository and is validated against shared parity fixtures. Thresholds are configurable design rules, not established accessibility cut-offs.

Based on different statistical definitions of discrimination, several methods have been proposed to detect and mitigate social inequality in machine learning models. This package aims to provide an alternative to fairness treatment in predictive models. The ROC method implemented in this package is described by Kamiran, Karim and Zhang (2012) <https://ieeexplore.ieee.org/document/6413831/>.

This package provides functions and data sets for the text Probability and Statistics with R.

This package provides tools for exploring projection pursuit classification tree using various projection pursuit indexes.

Particle swarm optimization - a basic variant.

This package provides a PNAS'-alike style for rmarkdown', derived from the Proceedings of the National Academy of Sciences of the United States of America ('PNAS') LaTeX style, and adapted for use with markdown and pandoc'.

This package provides tools to perform Pearson-Quetelet analysis on two-way contingency tables. The package computes absolute and relative frequencies, Quetelet indices, Pearson-Quetelet decomposition, apex tables, and chi-square summaries for interpreting associations between categorical variables.

This package provides tools for converting statistical results into consistent, publication-ready character output. Current functionality includes formatting p-values, confidence intervals, and correlation coefficients using publication-friendly conventions. The package emphasizes consistent reporting while preserving the underlying statistical results and statistical decision-making.

Collection of pivotal algorithms for: relabelling the MCMC chains in order to undo the label switching problem in Bayesian mixture models; fitting sparse finite mixtures; initializing the centers of the classical k-means algorithm in order to obtain a better clustering solution. For further details see Egidi, Pappadà , Pauli and Torelli (2018b)<ISBN:9788891910233>.

Patient Rule Induction Method (PRIM) for bump hunting in high-dimensional data.

An implementation of the parameter cascade method in Ramsay, J. O., Hooker,G., Campbell, D., and Cao, J. (2007) for estimating ordinary differential equation models with missing or complete observations. It combines smoothing method and profile estimation to estimate any non-linear dynamic system. The package also offers variance estimates for parameters of interest based on either bootstrap or Delta method.

Fast exponentiation when the exponent is an integer.

Pharmacokinetics is the study of drug absorption, distribution, metabolism, and excretion. The pharmacokinetics model explains that how the drug concentration change as the drug moves through the different compartments of the body. For pharmacokinetic modeling and analysis, it is essential to understand the basic pharmacokinetic parameters. All parameters are considered, but only some of parameters are used in the model. Therefore, we need to convert the estimated parameters to the other parameters after fitting the specific pharmacokinetic model. This package is developed to help this converting work. For more detailed explanation of pharmacokinetic parameters, see "Gabrielsson and Weiner" (2007), "ISBN-10: 9197651001"; "Benet and Zia-Amirhosseini" (1995) <DOI: 10.1177/019262339502300203>; "Mould and Upton" (2012) <DOI: 10.1038/psp.2012.4>; "Mould and Upton" (2013) <DOI: 10.1038/psp.2013.14>.

Make statistical inference on the probability of being in response, the duration of response, and the cumulative response rate up to a given time point. The method can be applied to analyze phase II randomized clinical trials with the endpoints being time to treatment response and time to progression or death.

This package provides general linear model facilities (single y-variable, multiple x-variables with arbitrary mixture of continuous and categorical and arbitrary interactions) for cross-species data. The method is, however, based on the nowadays rather uncommon situation in which uncertainty about a phylogeny is well represented by adopting a single polytomous tree. The theory is in A. Grafen (1989, Proc. R. Soc. B 326, 119-157) and aims to cope with both recognised phylogeny (closely related species tend to be similar) and unrecognised phylogeny (a polytomy usually indicates ignorance about the true sequence of binary splits).

This package provides a collection of R functions that are widely used by the Petersen Lab. Included are functions for various purposes, including evaluating the accuracy of judgments and predictions, performing scoring of assessments, generating correlation matrices, conversion of data between various types, data management, psychometric evaluation, extensions related to latent variable modeling, various plotting capabilities, and other miscellaneous useful functions. By making the package available, we hope to make our methods reproducible and replicable by others and to help others perform their data processing and analysis methods more easily and efficiently. The codebase is provided in Petersen (2025) <doi:10.5281/zenodo.7602890> and on CRAN': <doi: 10.32614/CRAN.package.petersenlab>. The package is described in "Principles of Psychological Assessment: With Applied Examples in R" (Petersen, 2024, 2025a) <doi:10.1201/9781003357421>, <doi:10.25820/work.007199>, <doi:10.5281/zenodo.6466589> and in "Fantasy Football Analytics: Statistics, Prediction, and Empiricism Using R" (Petersen, 2025b).

Optogenetics is a new tool to study neuronal circuits that have been genetically modified to allow stimulation by flashes of light. This package implements the methodological framework, Point-process Response model for Optogenetics (PRO), for analyzing data from these experiments. This method provides explicit nonlinear transformations to link the flash point-process with the spiking point-process. Such response functions can be used to provide important and interpretable scientific insights into the properties of the biophysical process that governs neural spiking in response to optogenetic stimulation.

This package provides a method for the quantitative prediction with much predictors. This package provides functions to construct the quantitative prediction model with less overfitting and robust to noise.

This package provides functions to measure Alpha, Beta and Gamma Proximity to Irreplaceability. The methods for Alpha and Beta irreplaceability were first described in: Baisero D., Schuster R. & Plumptre A.J. Redefining and Mapping Global Irreplaceability. Conservation Biology 2021;1-11. <doi:10.1111/cobi.13806>.

Calculate and optimize dynamic performance ratings of association football teams competing in matches, in accordance with the method used in the research paper "Determining the level of ability of football teams by dynamic ratings based on the relative discrepancies in scores between adversaries", by Constantinou and Fenton (2013) <doi:10.1515/jqas-2012-0036> This dynamic rating system has proven to provide superior results for predicting association football outcomes.