Personal wiki engine with a large language model (LLM) as research assistant. Supports guided sessions through a Claude Code <https://github.com/anthropics/claude-code> skill bundle and autonomous research runs from R via autoresearch(). Results land in a structured vault of markdown pages with YAML frontmatter and wikilinks, ready for hand-editing in your favourite editor alongside the LLM. Vaults are seeded with CLAUDE.md and AGENTS.md so Claude Code', Codex <https://github.com/openai/codex>, and other agents share the same operating instructions. Can adopt an existing Obsidian <https://obsidian.md/> vault in place via init_vault(adopt = TRUE).

This package provides a unified, computation-friendly framework for penalized principal machines (P2M), a class of sparse sufficient dimension reduction (SDR) estimators for regression and binary classification. Principal machines (PM) estimate the central subspace by solving a family of convex-loss problems over several cutoffs; their penalized counterparts (P2M) add a row-group sparsity penalty so that dimension reduction and variable selection are performed simultaneously. All estimators are fitted by a single group coordinate descent (GCD) algorithm that accommodates least squares, logistic, asymmetric least squares, L2-hinge, hinge (support vector machine, SVM) and quantile losses, together with the least absolute shrinkage and selection operator (LASSO), the smoothly clipped absolute deviation (SCAD) penalty and the minimax concave penalty (MCP). Methods are described in Li, Artemiou and Li (2011) <doi:10.1214/11-AOS932>, Shin and Artemiou (2017) <doi:10.1016/j.csda.2016.12.003>, Artemiou, Dong and Shin (2021) <doi:10.1016/j.patcog.2020.107768> and Breheny and Huang (2015) <doi:10.1007/s11222-013-9424-2>.

When using pooled p-values to adjust for multiple testing, there is an inherent balance that must be struck between rejection based on weak evidence spread among many tests and strong evidence in a few, explored in Salahub and Olford (2023) <arXiv:2310.16600>. This package provides functionality to compute marginal and central rejection levels and the centrality quotient for p-value pooling functions and provides implementations of the chi-squared quantile pooled p-value (described in Salahub and Oldford (2023)) and a proposal from Heard and Rubin-Delanchy (2018) <doi:10.1093/biomet/asx076> to control the quotient's value.

Perform tests for pleiotropy of multiple traits of various variable types on genotypes for a genetic marker.

The Prognostic Regression Offsets with Propagation of ERrors (for Treatment Effect Estimation) package facilitates direct adjustment for experiments and observational studies that is compatible with a range of study designs and covariance adjustment strategies. It uses explicit specification of clusters, blocks and treatment allocations to furnish probability of assignment-based weights targeting any of several average treatment effect parameters, and for standard error calculations reflecting these design parameters. For covariance adjustment of its Hajek and (one-way) fixed effects estimates, it enables offsetting the outcome against predictions from a dedicated covariance model, with standard error calculations propagating error as appropriate from the covariance model.

Quantitative trait loci (QTL) analysis and exploration of meiotic patterns in autopolyploid bi-parental F1 populations. For all ploidy levels, identity-by-descent (IBD) probabilities can be estimated. Significance thresholds, exploring QTL allele effects and visualising results are provided. For more background and to reference the package see <doi:10.1093/bioinformatics/btab574>.

Plot marginal effects for interactions estimated from linear models.

We provide comprehensive draft data for major professional sports leagues, including the National Football League (NFL), National Basketball Association (NBA), and National Hockey League (NHL). It offers access to both historical and current draft data, allowing for detailed analysis and research on player biases and player performance. The package is useful for sports fans and researchers interested in identifying biases and trends within scouting reports. Created by web scraping data from leading websites that cover professional sports player scouting reports, the package allows users to filter and summarize data for analytical purposes. For further details on the methods used, please refer to Wickham (2022) "rvest: Easily Harvest (Scrape) Web Pages" <https://CRAN.R-project.org/package=rvest> and Harrison (2023) "RSelenium: R Bindings for Selenium WebDriver" <https://CRAN.R-project.org/package=RSelenium>.

This package provides a tidyverse'-style interface to the Brazilian Central Bank (<https://www.bcb.gov.br>) PIX Open Data API <https://olinda.bcb.gov.br/olinda/servico/Pix_DadosAbertos/versao/v1/aplicacao#!/recursos>. Retrieve statistics on PIX keys, transactions by municipality, and monthly transaction summaries. All functions return tibbles and support OData query parameters for filtering, selecting, and ordering data.

The purpose of PH1XBAR is to build a Phase I Shewhart control chart for the basic Shewhart, the variance components and the ARMA models in R for subgrouped and individual data. More details can be found: Yao and Chakraborti (2020) <doi: 10.1002/qre.2793>, Yao and Chakraborti (2021) <doi: 10.1080/08982112.2021.1878220>, and Yao et al. (2023) <doi: 10.1080/00224065.2022.2139783>.

Create the density contour plot for bivariate inverse Gaussian distribution for given non negative random variables.

This package provides a robust approach for omics data integration and disease subtyping. PINSPlus is fast and supports the analysis of large datasets with hundreds of thousands of samples and features. The software automatically determines the optimal number of clusters and then partitions the samples in a way such that the results are robust against noise and data perturbation (Nguyen et al. (2019) <DOI: 10.1093/bioinformatics/bty1049>, Nguyen et al. (2017)<DOI: 10.1101/gr.215129.116>, Nguyen et al. (2021)<DOI: 10.3389/fonc.2021.725133>).

Supplementary utils for CRAN maintainers and R packages developers. Validating the library, packages and lock files. Exploring a complexity of a specific package like evaluating its size in bytes with all dependencies. The shiny app complexity could be explored too. Assessing the life duration of a specific package version. Checking a CRAN package check page status for any errors and warnings. Retrieving a DESCRIPTION or NAMESPACE file for any package version. Comparing DESCRIPTION or NAMESPACE files between different package versions. Getting a list of all releases for a specific package. The Bioconductor is partly supported.

This package provides functions to calculate and plot event and pointer years as well as resilience indices. Designed for dendroecological applications, but also suitable to analyze patterns in other ecological time series.

We implement two least-squares estimators under k-monotony constraint using a method based on the Support Reduction Algorithm from Groeneboom et al (2008) <DOI:10.1111/j.1467-9469.2007.00588.x>. The first one is a projection estimator on the set of k-monotone discrete functions. The second one is a projection on the set of k-monotone discrete probabilities. This package provides functions to generate samples from the spline basis from Lefevre and Loisel (2013) <DOI:10.1239/jap/1378401239>, and from mixtures of splines.

This package provides a collection of R Markdown templates for creating simple and easy to personalize single page websites.

Generation of multiple count, binary and ordinal variables simultaneously given the marginal characteristics and association structure. Throughout the package, the word Poisson is used to imply count data under the assumption of Poisson distribution. The details of the method are explained in Amatya, A. and Demirtas, H. (2015) <DOI:10.1080/00949655.2014.953534>.

Read depth data from genotyping-by-sequencing (GBS) or restriction site-associated DNA sequencing (RAD-seq) are imported and used to make Bayesian probability estimates of genotypes in polyploids or diploids. The genotype probabilities, posterior mean genotypes, or most probable genotypes can then be exported for downstream analysis. polyRAD is described by Clark et al. (2019) <doi:10.1534/g3.118.200913>, and the Hind/He statistic for marker filtering is described by Clark et al. (2022) <doi:10.1186/s12859-022-04635-9>. A variant calling pipeline for highly duplicated genomes is also included and is described by Clark et al. (2020, Version 1) <doi:10.1101/2020.01.11.902890>.

Facilitates the retrieval, spatial validation, and integration of flora and fauna occurrence records across administrative units (districts and provinces) in Peru. Retrieves official boundary geometries via geoperu', queries and consolidates observations from the Global Biodiversity Information Facility (GBIF, <https://www.gbif.org/>) and iNaturalist (<https://www.inaturalist.org/>), and standardizes attributes into a unified Darwin Core aligned structure. Designed for biodiversity assessments and spatial workflows within user-defined areas of interest.

An R6 class to set up, run, monitor, collate, and debug large simulation studies comprising many small independent replications and treatment configurations. Parallel processing, reproducibility, fault- and error-tolerance, and ability to resume an interrupted or timed-out simulation study are built in.

This package provides a native R client library for querying the Prometheus time-series database, using the PromQL query language.

Given a project schedule and associated costs, this package calculates the earned value to date. It is an implementation of Project Management Body of Knowledge (PMBOK) methodologies (reference Project Management Institute. (2021). A guide to the Project Management Body of Knowledge (PMBOK guide) (7th ed.). Project Management Institute, Newtown Square, PA, ISBN 9781628256673 (pdf)).

This package provides a function for estimating the transition probabilities in an illness-death model. The transition probabilities can be estimated from the unsmoothed landmark estimators developed by de Una-Alvarez and Meira-Machado (2015) <doi:10.1111/biom.12288>. Presmoothed estimates can also be obtained through the use of a parametric family of binary regression curves, such as logit, probit or cauchit. The additive logistic regression model and nonparametric regression are also alternatives which have been implemented. The idea behind the presmoothed landmark estimators is to use the presmoothing techniques developed by Cao et al. (2005) <doi:10.1007/s00180-007-0076-6> in the landmark estimation of the transition probabilities.

This package provides functions to compute p-values based on permutation tests. Regression, ANOVA and ANCOVA, omnibus F-tests, marginal unilateral and bilateral t-tests are available. Several methods to handle nuisance variables are implemented (Kherad-Pajouh, S., & Renaud, O. (2010) <doi:10.1016/j.csda.2010.02.015> ; Kherad-Pajouh, S., & Renaud, O. (2014) <doi:10.1007/s00362-014-0617-3> ; Winkler, A. M., Ridgway, G. R., Webster, M. A., Smith, S. M., & Nichols, T. E. (2014) <doi:10.1016/j.neuroimage.2014.01.060>). An extension for the comparison of signals issued from experimental conditions (e.g. EEG/ERP signals) is provided. Several corrections for multiple testing are possible, including the cluster-mass statistic (Maris, E., & Oostenveld, R. (2007) <doi:10.1016/j.jneumeth.2007.03.024>) and the threshold-free cluster enhancement (Smith, S. M., & Nichols, T. E. (2009) <doi:10.1016/j.neuroimage.2008.03.061>).