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Selection of informative features like genes, transcripts, RNA seq, etc. using Bootstrap Maximum Relevance and Minimum Redundancy technique from a given high dimensional genomic dataset. Informative gene selection involves identification of relevant genes and removal of redundant genes as much as possible from a large gene space. Main applications in high-dimensional expression data analysis (e.g. microarray data, NGS expression data and other genomics and proteomics applications).
In p >> n settings, full posterior sampling using existing Markov chain Monte Carlo (MCMC) algorithms is highly inefficient and often not feasible from a practical perspective. To overcome this problem, we propose a scalable stochastic search algorithm that is called the Simplified Shotgun Stochastic Search (S5) and aimed at rapidly explore interesting regions of model space and finding the maximum a posteriori(MAP) model. Also, the S5 provides an approximation of posterior probability of each model (including the marginal inclusion probabilities). This algorithm is a part of an article titled "Scalable Bayesian Variable Selection Using Nonlocal Prior Densities in Ultrahigh-dimensional Settings" (2018) by Minsuk Shin, Anirban Bhattacharya, and Valen E. Johnson and "Nonlocal Functional Priors for Nonparametric Hypothesis Testing and High-dimensional Model Selection" (2020+) by Minsuk Shin and Anirban Bhattacharya.
This package provides functions for training an optimal decision tree classifier, making predictions and generating latex code for plotting. Works for two-class and multi-class classification problems. The algorithm seeks the optimal Boolean rule consisting of multiple variables to split a node, resulting in shorter trees. Use bsnsing() to build a tree, predict() to make predictions and plot() to plot the tree into latex and PDF. See Yanchao Liu (2022) <arXiv:2205.15263> for technical details. Source code and more data sets are at <https://github.com/profyliu/bsnsing/>.
Easily create tables from data frames/matrices. Create/manipulate tables row-by-row, column-by-column or cell-by-cell. Use common formatting/styling to output rich tables as HTML', HTML widgets or to Excel'.
Making probabilistic projections of total fertility rate for all countries of the world, using a Bayesian hierarchical model <doi:10.1007/s13524-011-0040-5> <doi:10.18637/jss.v106.i08>. Subnational probabilistic projections are also supported <doi:10.4054/DemRes.2018.38.60>.
Estimates survival and mortality with covariates from census or capture-recapture/recovery data in a Bayesian framework when many individuals are of unknown age. It includes tools for data checking, model diagnostics and outputs such as life-tables and plots, as described in Colchero, Jones, and Rebke (2012) <doi:10.1111/j.2041-210X.2012.00186.x> and Colchero et al. (2021) <doi:10.1038/s41467-021-23894-3>.
Makes it easy to download financial data from Yahoo Finance <https://finance.yahoo.com/>.
Statistical methods for analyzing binary replicates, which are noisy binary measurements of latent binary states. Provides scoring functions (average, median, likelihood-based, and Bayesian) to estimate the probability that an individual is in the positive state. Includes maximum a posteriori estimation via the EM algorithm and full Bayesian inference via Stan. Supports classification with inconclusive decisions and prevalence estimation.
Package binr (pronounced as "binner") provides algorithms for cutting numerical values exhibiting a potentially highly skewed distribution into evenly distributed groups (bins). This functionality can be applied for binning discrete values, such as counts, as well as for discretization of continuous values, for example, during generation of features used in machine learning algorithms.
This package implements the Beta Kernel Process (BKP) for nonparametric modeling of spatially varying binomial probabilities, together with its extension, the Dirichlet Kernel Process (DKP), for categorical or multinomial data. The package provides functions for model fitting, predictive inference with uncertainty quantification, posterior simulation, and visualization in one-and two-dimensional input spaces. Multiple kernel functions (Gaussian, Matern 5/2, and Matern 3/2) are supported, with hyperparameters optimized through multi-start gradient-based search. For more details, see Zhao, Qing, and Xu (2025) <doi:10.48550/arXiv.2508.10447>.
Build and use B-splines for interpolation and regression. In case of regression, equality constraints as well as monotonicity and/or positivity of B-spline weights can be imposed. Moreover, knot positions can be on regular grid or be part of optimized parameters too (in addition to the spline weights). For this end, bspline is able to calculate Jacobian of basis vectors as function of knot positions. User is provided with functions calculating spline values at arbitrary points. These functions can be differentiated and integrated to obtain B-splines calculating derivatives/integrals at any point. B-splines of this package can simultaneously operate on a series of curves sharing the same set of knots. bspline is written with concern about computing performance that's why the basis and Jacobian calculation is implemented in C++. The rest is implemented in R but without notable impact on computing speed.
The purpose of this package is to fit the three Spatial Econometric Models proposed in Anselin (1988, ISBN:9024737354) in the homoscedastic and the heteroscedatic case. The fit is made through MCMC algorithms and observational working variables approach.
This package provides methods to estimate optimal dynamic treatment regimes using Bayesian likelihood-based regression approach as described in Yu, W., & Bondell, H. D. (2023) <doi:10.1093/jrsssb/qkad016> Uses backward induction and dynamic programming theory for computing expected values. Offers options for future parallel computing.
Implementations of Bayesian parametric, nonparametric and semiparametric procedures for univariate and multivariate time series. The package is based on the methods presented in C. Kirch et al (2018) <doi:10.1214/18-BA1126>, A. Meier (2018) <https://opendata.uni-halle.de//handle/1981185920/13470> and Y. Tang et al (2023) <doi:10.48550/arXiv.2303.11561>. It was supported by DFG grants KI 1443/3-1 and KI 1443/3-2.
Exposes the binary search functions of the C++ standard library (std::lower_bound, std::upper_bound) plus other convenience functions, allowing faster lookups on sorted vectors.
Bandwidth selectors for local linear quantile regression, including cross-validation and plug-in methods. The local linear quantile regression estimate is also implemented.
Bayesian hierarchical methods for the detection of differences in rates of related outcomes for multiple treatments for clustered observations (Carragher et al. (2020) <doi:10.1002/sim.8563>). This software was developed for the Precision Drug Theraputics: Risk Prediction in Pharmacoepidemiology project as part of a Rutherford Fund Fellowship at Health Data Research (UK), Medical Research Council (UK) award reference MR/S003967/1 (<https://gtr.ukri.org/>). Principal Investigator: Raymond Carragher.
Using a Bayesian estimation procedure, this package fits linear quantile regression models such as linear quantile models, linear quantile mixed models, quantile regression joint models for time-to-event and longitudinal data. The estimation procedure is based on the asymmetric Laplace distribution and the JAGS software is used to get posterior samples (Yang, Luo, DeSantis (2019) <doi:10.1177/0962280218784757>).
Building on the docking layout manager provided by blockr.dock', this provides an extension that allows for visualizing and manipulating a blockr board using a DAG-based user interface powered by the g6R graph visualisation HTML widget.
Determines effective sample size of a parametric prior distribution in Bayesian models. For a web-based Shiny application related to this package, see <https://implement.shinyapps.io/bayesess/>.
Developed for the following tasks. Simulating, computing maximum likelihood estimator, computing the Fisher information matrix, computing goodness-of-fit measures, and correcting bias of the ML estimator for a wide range of distributions fitted to units placed on progressive type-I interval censoring and progressive type-II censoring plans. The methods of Cox and Snell (1968) <doi:10.1111/j.2517-6161.1968.tb00724.x> and bootstrap method for computing the bias-corrected maximum likelihood estimator.
This package implements a wide variety of one- and two-parameter Bayesian CRM designs. The program can run interactively, allowing the user to enter outcomes after each cohort has been recruited, or via simulation to assess operating characteristics. See Sweeting et al. (2013): <doi:10.18637/jss.v054.i13>.
This package implements bidirectional two-stage least squares (Bi-TSLS) estimation for identifying bidirectional causal effects between two variables in the presence of unmeasured confounding. The method uses proxy variables (negative control exposure and outcome) along with at least one covariate to handle confounding.
This package provides arithmetic functions for R matrix and big.matrix objects as well as functions for QR factorization, Cholesky factorization, General eigenvalue, and Singular value decomposition (SVD). A method matrix multiplication and an arithmetic method -for matrix addition, matrix difference- allows for mixed type operation -a matrix class object and a big.matrix class object- and pure type operation for two big.matrix class objects.