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An optimized method for identifying mutually exclusive genomic events. Its main contribution is a statistical analysis based on the Poisson-Binomial distribution that takes into account that some samples are more mutated than others. See [Canisius, Sander, John WM Martens, and Lodewyk FA Wessels. (2016) "A novel independence test for somatic alterations in cancer shows that biology drives mutual exclusivity but chance explains most co-occurrence." Genome biology 17.1 : 1-17. <doi:10.1186/s13059-016-1114-x>]. The mutations matrices are sparse matrices. The method developed takes advantage of the advantages of this type of matrix to save time and computing resources.
This package provides a statistical tool for multivariate modeling and clustering using stepwise cluster analysis. The modeling output of rSCA is constructed as a cluster tree to represent the complicated relationships between multiple dependent and independent variables. A free tool (named rSCA Tree Generator) for visualizing the cluster tree from rSCA is also released and it can be downloaded at <https://rscatree.weebly.com/>.
Reporting tables often have structure that goes beyond simple rectangular data. The rtables package provides a framework for declaring complex multi-level tabulations and then applying them to data. This framework models both tabulation and the resulting tables as hierarchical, tree-like objects which support sibling sub-tables, arbitrary splitting or grouping of data in row and column dimensions, cells containing multiple values, and the concept of contextual summary computations. A convenient pipe-able interface is provided for declaring table layouts and the corresponding computations, and then applying them to data.
This package performs Principal Components Analysis (also known as PCA) dimensionality reduction in the context of a linear regression. In most cases, PCA dimensionality reduction is performed independent of the response variable for a regression. This captures the majority of the variance of the model's predictors, but may not actually be the optimal dimensionality reduction solution for a regression against the response variable. An alternative method, optimized for a regression against the response variable, is to use both PCA and a relative importance measure. This package applies PCA to a given data frame of predictors, and then calculates the relative importance of each PCA factor against the response variable. It outputs ordered factors that are optimized for model fit. By performing dimensionality reduction with this method, an individual can achieve a the same r-squared value as performing just PCA, but with fewer PCA factors. References: Yuri Balasanov (2017) <https://ilykei.com>.
Provide reproducible R chunks in R Markdown document that automatically check computational results for reproducibility. This is achieved by creating json files storing metadata about computational results. A comprehensive tutorial to the package is available as preprint by Brandmaier & Peikert (2024, <doi:10.31234/osf.io/3zjvf>).
Calculate RNNI distance between and manipulate with ranked trees. RNNI stands for Ranked Nearest Neighbour Interchange and is an extension of the classical NNI space (space of trees created by the NNI moves) to ranked trees, where internal nodes are ordered according to their heights (usually assumed to be times). The RNNI distance takes the tree topology into account, as standard NNI does, but also penalizes changes in the order of internal nodes, i.e. changes in the order of times of evolutionary events. For more information about the RNNI space see: Gavryushkin et al. (2018) <doi:10.1007/s00285-017-1167-9>, Collienne & Gavryushkin (2021) <doi:10.1007/s00285-021-01567-5>, Collienne et al. (2021) <doi:10.1007/s00285-021-01685-0>, and Collienne (2021) <http://hdl.handle.net/10523/12606>.
Packed bar charts are a variation of treemaps for visualizing skewed data. The concept was introduced by Xan Gregg at JMP'.
Estimates flexible epidemiological effect measures including both differences and ratios using the parametric G-formula developed as an alternative to inverse probability weighting. It is useful for estimating the impact of interventions in the presence of treatment-confounder-feedback. G-computation was originally described by Robbins (1986) <doi:10.1016/0270-0255(86)90088-6> and has been described in detail by Ahern, Hubbard, and Galea (2009) <doi:10.1093/aje/kwp015>; Snowden, Rose, and Mortimer (2011) <doi:10.1093/aje/kwq472>; and Westreich et al. (2012) <doi:10.1002/sim.5316>.
An extremely simple stack data type, implemented with R6 classes. The size of the stack increases as needed, and the amortized time complexity is O(1). The stack may contain arbitrary objects.
Randomization lists are an integral component of randomized clinical trials. randotools provides tools to easily create such lists.
This package provides a port of the C++ routine for applying the marching cubes algorithm written by Thomas Lewiner et al. (2012) <doi:10.1080/10867651.2003.10487582> into an R package. The package supplies the contour3d() function, which takes a 3-dimensional array of voxel data and calculates the vertices, vertex normals, and faces for a 3d mesh representing the contour(s) at a given level.
Interface for multiple data sources, such as the `EDDS` API <https://evds2.tcmb.gov.tr/index.php?/evds/userDocs> of the Central Bank of the Republic of Türkiye and the `FRED` API <https://fred.stlouisfed.org/docs/api/fred/> of the Federal Reserve Bank. Both data providers require API keys for access, which users can easily obtain by creating accounts on their respective websites. The package provides caching ability with the selection of periods to increase the speed and efficiency of requests. It combines datasets requested from different sources, helping users when the data has common frequencies. While combining data frames whenever possible, it also keeps all requested data available as separate data frames to increase efficiency.
This package provides R bindings for Tabulator JS <https://tabulator.info/>. Makes it a breeze to create highly customizable interactive tables in rmarkdown documents and shiny applications. It includes filtering, grouping, editing, input validation, history recording, column formatters, packaged themes and more.
It streamlines the evaluation of regression model assumptions, enhancing result reliability. With integrated tools for assessing key aspects like linearity, homoscedasticity, and more. It's a valuable asset for researchers and analysts working with regression models.
TROLL is coded in C++ and it typically simulates hundreds of thousands of individuals over hundreds of years. The rcontroll R package is a wrapper of TROLL'. rcontroll includes functions that generate inputs for simulations and run simulations. Finally, it is possible to analyse the TROLL outputs through tables, figures, and maps taking advantage of other R visualisation packages. rcontroll also offers the possibility to generate a virtual LiDAR point cloud that corresponds to a snapshot of the simulated forest.
Systematically transform immunoassay data, evaluate if the data is normally distributed, and pick the right method for cut point determination based on that evaluation. This package can also produce plots that are needed for reports, so data analysis and visualization can be done easily.
Rcpp11 includes a header only C++11 library that facilitates integration between R and modern C++.
This package implements the Zig-Zag algorithm (Bierkens, Fearnhead, Roberts, 2016) <arXiv:1607.03188> applied and Bouncy Particle Sampler <arXiv:1510.02451> for a Gaussian target and Student distribution.
Convert README.md to vignettes when installing packages without vignettes.
Implementation of an alternating direction method of multipliers algorithm for fitting a linear model with tree-based lasso regularization, which is proposed in Algorithm 1 of Yan and Bien (2020) <doi:10.1080/01621459.2020.1796677>. The package allows efficient model fitting on the entire 2-dimensional regularization path for large datasets. The complete set of functions also makes the entire process of tuning regularization parameters and visualizing results hassle-free.
Data sets, and functions for simulating and fitting nonlinear time series with minification and nonparametric models.
This package provides a flexible framework for implementing hierarchical access control in shiny applications. Features include user permission management through a two-tier system of access panels and units, pluggable shiny module for administrative interfaces, and support for multiple storage backends (local, AWS S3', Posit Connect'). The system enables fine-grained control over application features, with built-in audit trails and user management capabilities. Integrates seamlessly with Posit Connect's authentication system.
Database data model management utilities for R packages in the Observational Health Data Sciences and Informatics programme. ResultModelManager provides utility functions to allow package maintainers to migrate existing SQL database models, export and import results in consistent patterns.
This package provides random number generating functions that are much more context aware than the built-in functions. The functions are also much safer, as they check for incompatible values, and more reproducible.