This package provides functions in this package fit a stratified Cox proportional hazards and a proportional subdistribution hazards model by extending Zhang et al., (2007) <doi: 10.1016/j.cmpb.2007.07.010> and Zhang et al., (2011) <doi: 10.1016/j.cmpb.2010.07.005> respectively to clustered right-censored data. The functions also provide the estimates of the cumulative baseline hazard along with their standard errors. Furthermore, the adjusted survival and cumulative incidence probabilities are also provided along with their standard errors. Finally, the estimate of cumulative incidence and survival probabilities given a vector of covariates along with their standard errors are also provided.

This package provides a collection of functions to construct A-optimal block designs for comparing test treatments with one or more control(s). Mainly A-optimal balanced treatment incomplete block designs, weighted A-optimal balanced treatment incomplete block designs, A-optimal group divisible treatment designs and A-optimal balanced bipartite block designs can be constructed using the package. The designs are constructed using algorithms based on linear integer programming. To the best of our knowledge, these facilities to construct A-optimal block designs for comparing test treatments with one or more controls are not available in the existing R packages. For more details on designs for tests versus control(s) comparisons, please see Hedayat, A. S. and Majumdar, D. (1984) <doi:10.1080/00401706.1984.10487989> A-Optimal Incomplete Block Designs for Control-Test Treatment Comparisons, Technometrics, 26, 363-370 and Mandal, B. N. , Gupta, V. K., Parsad, Rajender. (2017) <doi:10.1080/03610926.2015.1071394> Balanced treatment incomplete block designs through integer programming. Communications in Statistics - Theory and Methods 46(8), 3728-3737.

Facilitates plotting audiometric data (mostly) by preparing the coordinate system according to standards, given e. g. in American Speech-Language-Hearing Association (2005), <doi:10.1044/policy.GL2005-00014>.

This package provides a few functions aim to provide a statistic tool for three purposes. First, simulate kin pairs data based on the assumption that every trait is affected by genetic effects (A), common environmental effects (C) and unique environmental effects (E).Second, use kin pairs data to fit an ACE model and get model fit output.Third, calculate power of A estimate given a specific condition. For the mechanisms of power calculation, we suggest to check Visscher(2004)<doi:10.1375/twin.7.5.505>.

This package implements a simple version of multivariate matching using a propensity score, near-exact matching, near-fine balance, and robust Mahalanobis distance matching (Rosenbaum 2020 <doi:10.1146/annurev-statistics-031219-041058>). You specify the variables, and the program does everything else.

Adaptive smoothing functions for estimating the blood oxygenation level dependent (BOLD) effect by using functional Magnetic Resonance Imaging (fMRI) data, based on adaptive Gauss Markov random fields, for real as well as simulated data. The implemented models make use of efficient Markov Chain Monte Carlo methods. Implemented methods are based on the research developed by A. Brezger, L. Fahrmeir, A. Hennerfeind (2007) <https://www.jstor.org/stable/4626770>.

Estimating and analyzing auto regressive integrated moving average (ARIMA) models. The primary function in this package is arima(), which fits an ARIMA model to univariate time series data using a random restart algorithm. This approach frequently leads to models that have model likelihood greater than or equal to that of the likelihood obtained by fitting the same model using the arima() function from the stats package. This package enables proper optimization of model likelihoods, which is a necessary condition for performing likelihood ratio tests. This package relies heavily on the source code of the arima() function of the stats package. For more information, please see Jesse Wheeler and Edward L. Ionides (2025) <doi:10.1371/journal.pone.0333993>.

An iterative implementation of a recursive binary partitioning algorithm to measure pairwise dependence with a modular design that allows user specification of the splitting logic and stop criteria. Helper functions provide suggested versions of both and support visualization and the computation of summary statistics on final binnings. For a thorough discussion and demonstration of the algorithm, see Salahub and Oldford (2025) <doi:10.1002/sam.70042>.

Utilities to parse authors fields from DESCRIPTION files and general purpose functions to deduplicate names in database, beyond the specific case of R package authors.

Weather indices are formed from weather variables in this package. The users can input any number of weather variables recorded over any number of weeks. This package has no restriction on the number of weeks and weather variables to be taken as input.The details of the method can be seen (i)'Joint effects of weather variables on rice yields by R. Agrawal, R. C. Jain and M. P. Jha in Mausam, vol. 34, pp. 189-194, 1983,<doi:10.54302/mausam.v34i2.2392>,(ii)'Improved weather indices based Bayesian regression model for forecasting crop yield by M. Yeasin, K. N. Singh, A. Lama and B. Gurung in Mausam, vol. 72, pp.879-886, 2021,<doi:10.54302/mausam.v72i4.670>.

Calculate AZTIâ s Marine Biotic Index - AMBI. The included list of benthic fauna species according to their sensitivity to pollution. Matching species in sample data to the list allows the calculation of fractions of individuals in the different sensitivity categories and thereafter the AMBI index. The Shannon Diversity Index H and the Danish benthic fauna quality index DKI (Dansk Kvalitetsindeks) can also be calculated, as well as the multivariate M-AMBI index. Borja, A., Franco, J. ,Pérez, V. (2000) "A marine biotic index to establish the ecological quality of soft bottom benthos within European estuarine and coastal environments" <doi:10.1016/S0025-326X(00)00061-8>.

The tools in this package are intended to help researchers assess multiple treatment-covariate interactions with data from a parallel-group randomized controlled clinical trial. The methods implemented in the package were proposed in Kovalchik, Varadhan and Weiss (2013) <doi: 10.1002/sim.5881>.

Stanford ATLAS (Advanced Temporal Search Engine) is a powerful tool that allows constructing cohorts of patients extremely quickly and efficiently. This package is designed to interface directly with an instance of ATLAS search engine and facilitates API queries and data dumps. Prerequisite is a good knowledge of the temporal language to be able to efficiently construct a query. More information available at <https://shahlab.stanford.edu/start>.

An interactive document on the topic of one-way and two-way analysis of variance using rmarkdown and shiny packages. Runtime examples are provided in the package function as well as at <https://tinyurl.com/ANOVAStatsTool>.

This package provides a toolbox for programming Clinical Data Standards Interchange Consortium (CDISC) compliant Analysis Data Model (ADaM) datasets in R. ADaM datasets are a mandatory part of any New Drug or Biologics License Application submitted to the United States Food and Drug Administration (FDA). Analysis derivations are implemented in accordance with the "Analysis Data Model Implementation Guide" (CDISC Analysis Data Model Team, 2021, <https://www.cdisc.org/standards/foundational/adam>). The package is an extension package of the admiral package for pediatric clinical trials.

High performance variant of apply() for a fixed set of functions. Considerable speedup of this implementation is a trade-off for universality: user defined functions cannot be used with this package. However, about 20 most currently employed functions are available for usage. They can be divided in three types: reducing functions (like mean(), sum() etc., giving a scalar when applied to a vector), mapping function (like normalise(), cumsum() etc., giving a vector of the same length as the input vector) and finally, vector reducing function (like diff() which produces result vector of a length different from the length of input vector). Optional or mandatory additional arguments required by some functions (e.g. norm type for norm()) can be passed as named arguments in ...'.

This package provides a set of tests for compositional pathologies. Tests for coherence of correlations with aIc.coherent() as suggested by (Erb et al. (2020) <doi:10.1016/j.acags.2020.100026>), compositional dominance of distance with aIc.dominant(), compositional perturbation invariance with aIc.perturb() as suggested by (Aitchison (1992) <doi:10.1007/BF00891269>) and singularity of the covariation matrix with aIc.singular(). Currently tests five data transformations: prop, clr, TMM, TMMwsp, and RLE from the R packages ALDEx2', edgeR and DESeq2 (Fernandes et al (2014) <doi:10.1186/2049-2618-2-15>, Anders et al. (2013)<doi:10.1038/nprot.2013.099>).

The AHP method (Analytic Hierarchy Process) is a multi-criteria decision-making method addressing choice and outranking problems. The method enables to perform the analysis of alternatives in each type of criterion and then provides a global performance of each alternative in the decision context. The main difference of this package is the possibility of evaluating the alternatives using quantitative data, by numerical representation, and qualitative data, using the Saaty scale, providing preference relation between variables by a pairwise evaluation.

Facilitate the analysis of data related to aquatic ecology, specifically the establishment of carbon budget. Currently, the package allows the below analysis. (i) the calculation of greenhouse gas flux based on data obtained from trace gas analyzer using the method described in Lin et al. (2024). (ii) the calculation of Dissolved Oxygen (DO) metabolism based on data obtained from dissolved oxygen data logger using the method described in Staehr et al. (2010). Yong et al. (2024) <doi:10.5194/bg-21-5247-2024>. Staehr et al. (2010) <doi:10.4319/lom.2010.8.0628>.

Causal discovery in linear structural equation models (Schultheiss, and Bühlmann (2023) <doi:10.1093/biomet/asad008>) and vector autoregressive models (Schultheiss, Ulmer, and Bühlmann (2025) <doi:10.1515/jci-2024-0011>) with explicit error control for false discovery, at least asymptotically.

The Algorithms for Quantitative Pedology (AQP) project was started in 2009 to organize a loosely-related set of concepts and source code on the topic of soil profile visualization, aggregation, and classification into this package (aqp). Over the past 8 years, the project has grown into a suite of related R packages that enhance and simplify the quantitative analysis of soil profile data. Central to the AQP project is a new vocabulary of specialized functions and data structures that can accommodate the inherent complexity of soil profile information; freeing the scientist to focus on ideas rather than boilerplate data processing tasks <doi:10.1016/j.cageo.2012.10.020>. These functions and data structures have been extensively tested and documented, applied to projects involving hundreds of thousands of soil profiles, and deeply integrated into widely used tools such as SoilWeb <https://casoilresource.lawr.ucdavis.edu/soilweb-apps>. Components of the AQP project (aqp, soilDB, sharpshootR, soilReports packages) serve an important role in routine data analysis within the USDA-NRCS Soil Science Division. The AQP suite of R packages offer a convenient platform for bridging the gap between pedometric theory and practice.

This package provides a varied array of mathematical derivations from various titrimetric and colorimetric methods for analyzing water quality parameters were condensed and integrated for the better physicochemical analysis. It is indispensable for managing any aquatic ecosystem, including aquaculture facilities. By substituting titrant and spectrophotometric absorbance readings, accurate determination of the concentrations of critical parameters such as Dissolved Oxygen, Free Carbon Dioxide, Total Alkalinity, Water Hardness, Hydrogen Sulfide, Total Ammonia Nitrogen, Nitrite, Nitrate, Chlorinity, Salinity, Inorganic Phosphate, and Transparency can be facilitated APHA(2017,ISBN:9780875532875).

This package provides functions to produce accessible HTML slides, HTML', Word and PDF documents from input R markdown files. Accessible PDF files are produced only on a Windows Operating System. One aspect of accessibility is providing a headings structure that is recognised by a screen reader, providing a navigational tool for a blind or partially-sighted person. A key aim is to produce documents of different formats easily from each of a collection of R markdown source files. Input R markdown files are rendered using the render() function from the rmarkdown package <https://cran.r-project.org/package=rmarkdown>. A zip file containing multiple output files can be produced from one function call. A user-supplied template Word document can be used to determine the formatting of an output Word document. Accessible PDF files are produced from Word documents using OfficeToPDF <https://github.com/cognidox/OfficeToPDF>. A convenience function, install_otp() is provided to install this software. The option to print HTML output to (non-accessible) PDF files is also available.

Toolbox for the experimental aquatic chemist, focused on acidification and CO2 air-water exchange. It contains all elements to model the pH, the related CO2 air-water exchange, and aquatic acid-base chemistry for an arbitrary marine, estuarine or freshwater system. It contains a suite of tools for sensitivity analysis, visualisation, modelling of chemical batches, and can be used to build dynamic models of aquatic systems. As from version 1.0-4, it also contains functions to calculate the buffer factors.