Este paquete tiene la finalidad de ayudar a aprender de una forma interactiva, teniendo ejemplos y la posibilidad de resolver nuevos al mismo tiempo. Apuntes de clase interactivos.

This package provides extensions for package sitree for allometric variables, growth, mortality, recruitment, management, tree removal and external modifiers functions.

This package provides a suite of statistical methods for analysis of single-cell omics data including linear model-based methods for differential abundance analysis for individual level single-cell RNA-seq data. For more details see Zhang, et al. (Submitted to Bioinformatics)<https://github.com/Lujun995/DiSC_Replication_Code>.

Offers Bayesian semiparametric density estimation and tail-index estimation for heavy tailed data, by using a parametric, tail-respecting transformation of the data to the unit interval and then modeling the transformed data with a purely nonparametric logistic Gaussian process density prior. Based on Tokdar et al. (2022) <doi:10.1080/01621459.2022.2104727>.

The goal of stim is to provide a function for estimating the Stability Informed Model. The Stability Informed Model integrates stability information (how much a variable correlates with itself in the future) into cross-sectional estimates. Wysocki and Rhemtulla (2022) <https://psyarxiv.com/vg5as>.

Computes the entire solution paths for Support Vector Regression(SVR) with respect to the regularization parameter, lambda and epsilon in epsilon-intensive loss function, efficiently. We call each path algorithm svrpath and epspath. See Wang, G. et al (2008) <doi:10.1109/TNN.2008.2002077> for details regarding the method.

This package provides a system enables cross study Analysis by extracting and filtering study data for control animals from CDISC SEND Study Repository. These data types are supported: Body Weights, Laboratory test results and Microscopic findings. These database types are supported: SQLite and Oracle'.

This package implements S3 classes for storing dates and date-times based on the Jalali calendar. The main design goal of shide is consistency with base R's Date and POSIXct'. It provide features such as: date-time parsing, formatting and arithmetic.

Simulate a virtual population of subjects that has demographic distributions (height, weight, and BMI) and correlations (height and weight), by sex and age, which mimic those reported in real-world anthropometric growth charts (CDC, WHO, or Fenton).

Generates, plays, and solves Sudoku puzzles. The GUI playSudoku() needs package "tkrplot" if you are not on Windows.

Given bincount data from single-cell copy number profiling (segmented or unsegmented), estimates ploidy, and uses the ploidy estimate to scale the data to absolute copy numbers. Uses the modular quantogram proposed by Kendall (1986) <doi:10.1002/0471667196.ess2129.pub2>, modified by weighting segments according to confidence, and quantifying confidence in the estimate using a theoretical quantogram. Includes optional fused-lasso segmentation with the algorithm in Johnson (2013) <doi:10.1080/10618600.2012.681238>, using the implementation from glmgen by Arnold, Sadhanala, and Tibshirani.

Estimates unit-level and population-level parameters from a hierarchical model in marketing applications. The package includes: Hierarchical Linear Models with a mixture of normals prior and covariates, Hierarchical Multinomial Logits with a mixture of normals prior and covariates, Hierarchical Multinomial Logits with a Dirichlet Process prior and covariates. For more details, see Bumbaca, F. (Rico), Misra, S., & Rossi, P. E. (2020) <doi:10.1177/0022243720952410> "Scalable Target Marketing: Distributed Markov Chain Monte Carlo for Bayesian Hierarchical Models". Journal of Marketing Research, 57(6), 999-1018.

Computes the required sample size for estimation of totals, means and proportions under complex sampling designs.

Based on the illness-death model a large number of clinical trials with oncology endpoints progression-free survival (PFS) and overall survival (OS) can be simulated, see Meller, Beyersmann and Rufibach (2019) <doi:10.1002/sim.8295>. The simulation set-up allows for random and event-driven censoring, an arbitrary number of treatment arms, staggered study entry and drop-out. Exponentially, Weibull and piecewise exponentially distributed survival times can be generated. The correlation between PFS and OS can be calculated.

Create Upset plots using a combination of ggplot2 and patchwork'.

Single cell resolution data has been valuable in learning about tissue microenvironments and interactions between cells or spots. This package allows for the simulation of this level of data, be it single cell or â spotsâ , in both a univariate (single metric or cell type) and bivariate (2 or more metrics or cell types) ways. As more technologies come to marker, more methods will be developed to derive spatial metrics from the data which will require a way to benchmark methods against each other. Additionally, as the field currently stands, there is not a gold standard method to be compared against. We set out to develop an R package that will allow users to simulate point patterns that can be biologically informed from different tissue domains, holes, and varying degrees of clustering/colocalization. The data can be exported as spatial files and a summary file (like HALO'). <https://github.com/FridleyLab/scSpatialSIM/>.

Manage package documentation and namespaces from the command line. Programmatically attach namespaces in R and Rmd script, populates Roxygen2 skeletons with information scraped from within functions and populate the Imports field of the DESCRIPTION file.

Last.fm'<https://www.last.fm> is a music platform focussed on building a detailed profile of a users listening habits. It does this by scrobbling (recording) every track you listen to on other platforms ('spotify', youtube', soundcloud etc) and transferring them to your Last.fm database. This allows Last.fm to act as a complete record of your entire listening history. scrobbler provides helper functions to download and analyse your listening history in R.

Execute the self-controlled case series (SCCS) design using observational data in the OMOP Common Data Model. Extracts all necessary data from the database and transforms it to the format required for SCCS. Age and season can be modeled using splines assuming constant hazard within calendar months. Event-dependent censoring of the observation period can be corrected for. Many exposures can be included at once (MSCCS), with regularization on all coefficients except for the exposure of interest. Includes diagnostics for all major assumptions of the SCCS.

Estimation for longitudinal data following outcome dependent sampling using the sequential offsetted regression technique. Includes support for binary, count, and continuous data. The first regression is a logistic regression, which uses a known ratio (the probability of being sampled given that the subject/observation was referred divided by the probability of being sampled given that the subject/observation was no referred) as an offset to estimate the probability of being referred given outcome and covariates. The second regression uses this estimated probability to calculate the mean population response given covariates.

This package provides functions for calculating species richness for rarefaction and extrapolation, primarily non-parametric species richness such as jackknife, Chao1, and ACE. Also available are functions for plotting species richness and extrapolation curves, and computing standard diversity and entropy indices.

The statistical tools in this package do one of four things: 1) Enhance basic statistical functions with more flexible inputs, smarter defaults, and richer, clearer, and ready-to-use output (e.g., t.test2()) 2) Produce publication-ready commonly needed figures with one line of code (e.g., plot_cdf()) 3) Implement novel analytical tools developed by the authors (e.g., twolines()) 4) Deliver niche functions of high value to the authors that are not easily available elsewhere (e.g., clear(), convert_to_sql(), resize_images()).

The definition of fuzzy random variable and the methods of simulation from fuzzy random variables are two challenging statistical problems in three recent decades. This package is organized based on a special definition of fuzzy random variable and simulate fuzzy random variable by Piecewise Linear Fuzzy Numbers (PLFNs); see Coroianua et al. (2013) <doi:10.1016/j.fss.2013.02.005> for details about PLFNs. Some important statistical functions are considered for obtaining the membership function of main statistics, such as mean, variance, summation, standard deviation and coefficient of variance. Some of applied advantages of Sim.PLFN package are: (1) Easily generating / simulation a random sample of PLFN, (2) drawing the membership functions of the simulated PLFNs or the membership function of the statistical result, and (3) Considering the simulated PLFNs for arithmetic operation or importing into some statistical computation. Finally, it must be mentioned that Sim.PLFN package works on the basis of FuzzyNumbers package.

To calculate the standard error of measurement (SEM) to assess the observer variability (inter- and intra-observer variation). The methods used in this package are referenced from Zoran B. PopoviÄ (2017) <doi:10.21037/cdt.2017.03.12>.