Diagnostics and data preparation for random effects within estimator, random effects within-idiosyncratic estimator, between-within-idiosyncratic model, and cross-classified between model. Mundlak, Yair (1978) <doi:10.2307/1913646>. Hausman, Jeffrey (1978) <doi:10.2307/1913827>. Allison, Paul (2009) <doi:10.4135/9781412993869>. Neuhaus, J.M., and J. D. Kalbfleisch (1998) <doi:10.2307/3109770>.

Allows loading and displaying an Observable notebook (online JavaScript notebooks powered by <https://observablehq.com>) as an HTML Widget in an R session, shiny application or rmarkdown document.

Predicts statistics of a reference distribution from a mixture of raw clinical measurements (healthy and pathological). Uses pretrained CNN models to estimate the mean, standard deviation, and reference fraction from 1D or 2D sample data. Methods are described in LeBien, Velev, and Roche-Lima (2026) "RINet: synthetic data training for indirect estimation of clinical reference distributions" <doi:10.1016/j.jbi.2026.104980>.

Interface for the Google Ads API'. Google Ads is an online advertising service that enables advertisers to display advertising to web users (see <https://developers.google.com/google-ads/> for more information).

This reduced piecewise exponential survival software implements the likelihood ratio test and backward elimination procedure in Han, Schell, and Kim (2012 <doi:10.1080/19466315.2012.698945>, 2014 <doi:10.1002/sim.5915>), and Han et al. (2016 <doi:10.1111/biom.12590>). Inputs to the program can be either times when events/censoring occur or the vectors of total time on test and the number of events. Outputs of the programs are times and the corresponding p-values in the backward elimination. Details about the model and implementation are given in Han et al. 2014. This program can run in R version 3.2.2 and above.

Building interactive web applications with R is incredibly easy with shiny'. Behind the scenes, shiny builds a reactive graph that can quickly become intertwined and difficult to debug. reactlog (Schloerke 2019) <doi:10.5281/zenodo.2591517> provides a visual insight into that black box of shiny reactivity by constructing a directed dependency graph of the application's reactive state at any time point in a reactive recording.

This package provides access to global river gauge data from a variety of national-level river agencies. The package interfaces with the national-level agency websites to provide access to river gauge locations, river discharge, and river stage. Currently, the package is available for the following countries: Argentina, Australia, Brazil, Canada, Chile, France, Germany, Japan, South Africa, the United Kingdom, and the United States.

Bindings for additional models for use with the parsnip package. Models include prediction rule ensembles (Friedman and Popescu, 2008) <doi:10.1214/07-AOAS148>, C5.0 rules (Quinlan, 1992 ISBN: 1558602380), and Cubist (Kuhn and Johnson, 2013) <doi:10.1007/978-1-4614-6849-3>.

This package performs robust and sparse correlation matrix estimation. Robustness is achieved based on a simple robust pairwise correlation estimator, while sparsity is obtained based on thresholding. The optimal thresholding is tuned via cross-validation. See Serra, Coretto, Fratello and Tagliaferri (2018) <doi:10.1093/bioinformatics/btx642>.

Slow Feature Analysis (SFA), ported to R based on matlab implementations of SFA: SFA toolkit 1.0 by Pietro Berkes and SFA toolkit 2.8 by Wolfgang Konen.

This package provides functions to handle command-line arguments for R scripting. It enables building stand-alone R programs that accept and parse command-line options in BIOS style. Zhang (2025) <https://github.com/bedapub/ribiosArg>.

Compute the repeated measures correlation, a statistical technique for determining the overall within-individual relationship among paired measures assessed on two or more occasions, first introduced by Bland and Altman (1995). Includes functions for diagnostics, p-value, effect size with confidence interval including optional bootstrapping, as well as graphing. Also includes several example datasets. For more details, see the web documentation <https://lmarusich.github.io/rmcorr/index.html> and the original paper: Bakdash and Marusich (2017) <doi:10.3389/fpsyg.2017.00456>.

Estimates structural equation models by case-based least squares: the latent scores of every observation are treated as free variables of a constrained optimization problem, so that arbitrary nonlinear model equations, bounds and constraints on latent variables and inequality constraints on parameters become possible. Model equations are specified as plain text (e.g. "y == a*exp(b*eta)"). Gradients are obtained by automatic differentiation via RTMB', and the constrained problem is solved with nloptr (SLSQP or augmented Lagrangian). Missing data are handled case-wise. The methodology is described in Oldenburg (2024) <doi:10.19139/soic-2310-5070-1868> and Oldenburg (2025) <doi:10.19139/soic-2310-5070-2324>.

Reversion mutations are secondary mutations that reverse the deleterious effects of an original pathogenic mutation, partially or fully restoring the gene's function. The revert package detects reversion mutations for a specific pathogenic mutation from DNA-seq bam files.

Enhances the R Optimization Infrastructure ('ROI') package with the quadratic solver OSQP'. More information about OSQP can be found at <https://osqp.org>.

Toolkit to interact with the SOAP web services of the SEI (Sistema Eletronico de Informacoes), the electronic system for document and process management widely used by Brazilian public administration bodies. Provides functions to build the SOAP envelopes, perform the requests, handle SOAP faults, and parse the XML responses into data frames. Covers process and document queries, listing services, write operations (creating processes and documents, sending and signing off processes, blocks, deadlines and markers) and the permission services of the companion SIP system. Note that access to the web services is restricted by the server to previously authorized network addresses. For more information about the SEI system and its web services see <https://www.gov.br/gestao/pt-br/assuntos/processo-eletronico-nacional>.

An R implementation of the Reinert text clustering method. For more details about the algorithm see the included vignettes or Reinert (1990) <doi:10.1177/075910639002600103>.

Gene-environment (GÃ E) interactions have important implications to elucidate the etiology of complex diseases beyond the main genetic and environmental effects. Outliers and data contamination in disease phenotypes of GÃ E studies have been commonly encountered, leading to the development of a broad spectrum of robust penalization methods. Nevertheless, within the Bayesian framework, the issue has not been taken care of in existing studies. We develop a robust Bayesian variable selection method for GÃ E interaction studies. The proposed Bayesian method can effectively accommodate heavy-tailed errors and outliers in the response variable while conducting variable selection by accounting for structural sparsity. In particular, the spike-and-slab priors have been imposed on both individual and group levels to identify important main and interaction effects. An efficient Gibbs sampler has been developed to facilitate fast computation. The Markov chain Monte Carlo algorithms of the proposed and alternative methods are efficiently implemented in C++.

This package provides tools for manipulating, exploring, and visualising multiple-response data, including scored or ranked responses. Conversions to and from factors, lists, strings, matrices; reordering, lumping, flattening; set operations; tables; frequency and co-occurrence plots.

Rasch model and extensions for survey data, using Conditional Maximum likelihood (CML). Carlo Cafiero, Sara Viviani, Mark Nord (2018) <doi:10.1016/j.measurement.2017.10.065>.

Read Statistical Data and Metadata Exchange (SDMX) XML data. This the main transmission format used in official statistics. Data can be imported from local SDMX-ML files or a SDMX web-service and will be read in as is into a dataframe object. The RapidXML C++ library <https://rapidxml.sourceforge.net/> is used to parse the XML data.

This package provides a Pure R implementation of Bayesian Global Optimization with Gaussian Processes.

Execute FOCAL (<https://en.wikipedia.org/wiki/FOCAL_(programming_language)>) source code directly in R'. This is achieved by translating FOCAL code into equivalent R commands and controlling the sequence of execution.

Fits standard and random effects latent class models. The single level random effects model is described in Qu et al <doi:10.2307/2533043> and the two level random effects model in Beath and Heller <doi:10.1177/1471082X0800900302>. Examples are given for their use in diagnostic testing.