The provided benchmark suite enables the automated evaluation and comparison of any existing and novel indirect method for reference interval ('RI') estimation in a systematic way. Indirect methods take routine measurements of diagnostic tests, containing pathological and non-pathological samples as input and use sophisticated statistical methods to derive a model describing the distribution of the non-pathological samples, which can then be used to derive reference intervals. The benchmark suite contains 5,760 simulated test sets with varying difficulty. To include any indirect method, a custom wrapper function needs to be provided. The package offers functions for generating the test sets, executing the indirect method and evaluating the results. See ?RIbench or vignette("RIbench_package") for a more comprehensive description of the features. A detailed description and application is described in Ammer T., Schuetzenmeister A., Prokosch H.-U., Zierk J., Rank C.M., Rauh M. "RIbench: A Proposed Benchmark for the Standardized Evaluation of Indirect Methods for Reference Interval Estimation". Clinical Chemistry (2022) <doi:10.1093/clinchem/hvac142>.

This package provides a single key function, Require that makes rerun-tolerant versions of install.packages and require for CRAN packages, packages no longer on CRAN (i.e., archived), specific versions of packages, and GitHub packages. This approach is developed to create reproducible workflows that are flexible and fast enough to use while in development stages, while able to build snapshots once a stable package collection is found. As with other functions in a reproducible workflow, this package emphasizes functions that return the same result whether it is the first or subsequent times running the function, with subsequent times being sufficiently fast that they can be run every time without undue waiting burden on the user or developer.

Floating Percentile Model with additional functions for optimizing inputs and evaluating outputs and assumptions.

Standardized methods for calculating common important derived physical features of lakes including water density based based on temperature, thermal layers, thermocline depth, lake number, Wedderburn number, Schmidt stability and others.

Convert README.md to vignettes when installing packages without vignettes.

This package provides a client for the API of OpenDota. OpenDota is a web service which is provide DOTA2 real time data. Data is collected through the Steam WebAPI. With ROpenDota you can easily grab the latest DOTA2 statistics in R programming such as latest match on official international competition, analyzing your or enemy performance to learn their strategies,etc. Please see <https://github.com/rosdyana/ROpenDota> for more information.

Robust estimators for generalized ratio model (Wada, Sakashita and Tsubaki, 2021)<doi:10.17713/ajs.v50i1.994> and linear regression model by the IRLS(iterative reweighted least squares) algorithm are contained.

Multivariate regression methodologies including classical reduced-rank regression (RRR) studied by Anderson (1951) <doi:10.1214/aoms/1177729580> and Reinsel and Velu (1998) <doi:10.1007/978-1-4757-2853-8>, reduced-rank regression via adaptive nuclear norm penalization proposed by Chen et al. (2013) <doi:10.1093/biomet/ast036> and Mukherjee et al. (2015) <doi:10.1093/biomet/asx080>, robust reduced-rank regression (R4) proposed by She and Chen (2017) <doi:10.1093/biomet/asx032>, generalized/mixed-response reduced-rank regression (mRRR) proposed by Luo et al. (2018) <doi:10.1016/j.jmva.2018.04.011>, row-sparse reduced-rank regression (SRRR) proposed by Chen and Huang (2012) <doi:10.1080/01621459.2012.734178>, reduced-rank regression with a sparse singular value decomposition (RSSVD) proposed by Chen et al. (2012) <doi:10.1111/j.1467-9868.2011.01002.x> and sparse and orthogonal factor regression (SOFAR) proposed by Uematsu et al. (2019) <doi:10.1109/TIT.2019.2909889>.

Implementation of the shuffle estimator, a non-parametric estimator for signal and noise variance under mild noise correlations.

Sensitivity analysis in unmatched observational studies, with or without strata. The main functions are sen2sample() and senstrat(). See Rosenbaum, P. R. and Krieger, A. M. (1990), JASA, 85, 493-498, <doi:10.1080/01621459.1990.10476226> and Gastwirth, Krieger and Rosenbaum (2000), JRSS-B, 62, 545â 555 <doi:10.1111/1467-9868.00249> .

Load and export SomaScan data via the SomaLogic Operating Co., Inc. structured text file called an ADAT ('*.adat'). For file format see <https://github.com/SomaLogic/SomaLogic-Data/blob/main/README.md>. The package also exports auxiliary functions for manipulating, wrangling, and extracting relevant information from an ADAT object once in memory.

The Patient Rule Induction Method (PRIM) is typically used for "bump hunting" data mining to identify regions with abnormally high concentrations of data with large or small values. This package extends this methodology so that it can be applied to binary classification problems and used for prediction.

Enables deploying configuration file-based shiny apps with minimal programming for interactive exploration and analysis showcase of molecular expression data. For exploration, supports visualization of correlations between rows of an expression matrix and a table of observations, such as clinical measures, and comparison of changes in expression over time. For showcase, enables visualizing the results of differential expression from package such as limma', co-expression modules from WGCNA and lower dimensional projections.

Computes the entire solution paths for Support Vector Regression(SVR) with respect to the regularization parameter, lambda and epsilon in epsilon-intensive loss function, efficiently. We call each path algorithm svrpath and epspath. See Wang, G. et al (2008) <doi:10.1109/TNN.2008.2002077> for details regarding the method.

Models high-dimensional data, such as RNA-seq or proteomic data using an item-by-item strategy. The package contains functions to wrap high-dimensional data and iterate over them using established R packages for regression modelling (e.g., glmmTMB or mgcv').

This package performs cluster analysis of mixed-type data using Spectral Clustering, see F. Mbuga and, C. Tortora (2022) <doi:10.3390/stats5010001>.

Implement the algorithm provided in scan for estimating the transmission route on railway network using passenger volume. It is a generalization of the scan statistic approach for railway network to identify the hot railway route for transmitting infectious diseases.

This package provides a framework for simulating spatially explicit genomic data which leverages real cartographic information for programmatic and visual encoding of spatiotemporal population dynamics on real geographic landscapes. Population genetic models are then automatically executed by the SLiM software by Haller et al. (2019) <doi:10.1093/molbev/msy228> behind the scenes, using a custom built-in simulation SLiM script. Additionally, fully abstract spatial models not tied to a specific geographic location are supported, and users can also simulate data from standard, non-spatial, random-mating models. These can be simulated either with the SLiM built-in back-end script, or using an efficient coalescent population genetics simulator msprime by Baumdicker et al. (2022) <doi:10.1093/genetics/iyab229> with a custom-built Python script bundled with the R package. Simulated genomic data is saved in a tree-sequence format and can be loaded, manipulated, and summarised using tree-sequence functionality via an R interface to the Python module tskit by Kelleher et al. (2019) <doi:10.1038/s41588-019-0483-y>. Complete model configuration, simulation and analysis pipelines can be therefore constructed without a need to leave the R environment, eliminating friction between disparate tools for population genetic simulations and data analysis.

Structural handling of identity numbers used in the Swedish administration such as personal identity numbers ('personnummer') and organizational identity numbers ('organisationsnummer').

This package provides spatial datasets ready to use for ecological modelling and raster companion data for prediction: Neanderthal presence during the Last Interglacial (Benito et al. 2017 <doi:10.1111/jbi.12845>); Plant diversity metrics for the World's Ecoregions (Maestre et al. 2021 <doi:10.1111/nph.17398>); tree richness across the Americas (Benito et al. 2013 <doi:10.1111/2041-210X.12022>); plant communities from the Sierra Nevada (Spain) with future climate scenarios (Benito et al. 2013 <doi:10.1111/2041-210X.12022>); butterfly-plant interaction data from Sierra Nevada (Spain) (Benito et al. 2011 <doi:10.1007/s10584-010-0015-3>); plant species occurrences in Andalusia (Spain) (Benito et al. 2014 <doi:10.1111/ddi.12148>); presence of the plant Linaria nigricans and greenhouses (Benito et al. 2009 <doi:10.1007/s10531-009-9604-8>); global NDVI and environmental predictors, and European oak species occurrences. All datasets include pre-processed environmental predictors ready for statistical modelling.

Statnet is a collection of packages for statistical network analysis that are designed to work together because they share common data representations and API design. They provide an integrated set of tools for the representation, visualization, analysis, and simulation of many different forms of network data. This package is designed to make it easy to install and load the key statnet packages in a single step. Learn more about statnet at <http://www.statnet.org>. Tutorials for many packages can be found at <https://github.com/statnet/Workshops/wiki>. For an introduction to functions in this package, type help(package='statnet').

This package provides fundamental function support for SigBridgeR and its single-cell phenotypic screening algorithm, including optional functions.

Sparse redundancy analysis for high dimensional (biomedical) data. Directional multivariate analysis to express the maximum variance in the predicted data set by a linear combination of variables of the predictive data set. Implemented in a partial least squares framework, for more details see Csala et al. (2017) <doi:10.1093/bioinformatics/btx374>.

Given raster files directly downloaded from various websites, it generates a raster structure where it merges them if they are tiles of the same scene and classifies them according to their spectral and spatial resolution for easy access by name.