This package provides confidence intervals in least-squares regressions when the variable of interest has a shift-share structure, and in instrumental variables regressions when the instrument has a shift-share structure. The confidence intervals implement the AKM and AKM0 methods developed in Adão, Kolesár, and Morales (2019) <doi:10.1093/qje/qjz025>.

RCON(V, E) models are a kind of restriction of the Gaussian Graphical Models defined by a set of equality constraints on the entries of the concentration matrix. sglasso package implements the structured graphical lasso (sglasso) estimator proposed in Abbruzzo et al. (2014) for the weighted l1-penalized RCON(V, E) model. Two cyclic coordinate algorithms are implemented to compute the sglasso estimator, i.e. a cyclic coordinate minimization (CCM) and a cyclic coordinate descent (CCD) algorithm.

An implementation of Simultaneous Truth and Performance Level Estimation (STAPLE) <doi:10.1109/TMI.2004.828354>. This method is used when there are multiple raters for an object, typically an image, and this method fuses these ratings into one rating. It uses an expectation-maximization method to estimate this rating and the individual specificity/sensitivity for each rater.

This package performs parametric and non-parametric estimation and simulation for multi-state discrete-time semi-Markov processes. For the parametric estimation, several discrete distributions are considered for the sojourn times: Uniform, Geometric, Poisson, Discrete Weibull and Negative Binomial. The non-parametric estimation concerns the sojourn time distributions, where no assumptions are done on the shape of distributions. Moreover, the estimation can be done on the basis of one or several sample paths, with or without censoring at the beginning or/and at the end of the sample paths. Reliability indicators such as reliability, maintainability, availability, BMP-failure rate, RG-failure rate, mean time to failure and mean time to repair are available as well. The implemented methods are described in Barbu, V.S., Limnios, N. (2008) <doi:10.1007/978-0-387-73173-5>, Barbu, V.S., Limnios, N. (2008) <doi:10.1080/10485250701261913> and Trevezas, S., Limnios, N. (2011) <doi:10.1080/10485252.2011.555543>. Estimation and simulation of discrete-time k-th order Markov chains are also considered.

Various tools for semantic vector spaces, such as correspondence analysis (simple, multiple and discriminant), latent semantic analysis, probabilistic latent semantic analysis, non-negative matrix factorization, latent class analysis, EM clustering, logratio analysis and log-multiplicative (association) analysis. Furthermore, there are specialized distance measures, plotting functions and some helper functions.

Compute ploidy of single cells (or nuclei) based on single-cell (or single-nucleus) ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing) data <https://github.com/fumi-github/scPloidy>.

This package provides functions for creating and annotating a composite plot in ggplot2'. Offers background themes and shortcut plotting functions that produce figures that are appropriate for the format of scientific journals. Some methods are described in Min and Zhou (2021) <doi:10.3389/fgene.2021.802894>.

Implement a GAM-based (Generalized Additive Models) spatial surplus production model (spatial SPM), aimed at modeling northern shrimp population in Atlantic Canada but potentially to any stock in any location. The package is opinionated in its implementation of SPMs as it internally makes the choice to use penalized spatial gams with time lags. However, it also aims to provide options for the user to customize their model. The methods are described in Pedersen et al. (2022, <https://www.dfo-mpo.gc.ca/csas-sccs/Publications/ResDocs-DocRech/2022/2022_062-eng.html>).

Implement a promising, and yet little explored protocol for bioacoustical analysis, the eigensound method by MacLeod, Krieger and Jones (2013) <doi:10.4404/hystrix-24.1-6299>. Eigensound is a multidisciplinary method focused on the direct comparison between stereotyped sounds from different species. SoundShape', in turn, provide the tools required for anyone to go from sound waves to Principal Components Analysis, using tools extracted from traditional bioacoustics (i.e. tuneR and seewave packages), geometric morphometrics (i.e. geomorph package) and multivariate analysis (e.g. stats package). For more information, please see Rocha and Romano (2021) and check SoundShape repository on GitHub for news and updates <https://github.com/p-rocha/SoundShape>.

Quantify stratigraphic disorder using the metrics defined by Burgess (2016) <doi:10.2110/jsr.2016.10>. Contains a range of utility tools to construct and manipulate stratigraphic columns.

Dual interfaces, graphical and programmatic, designed for intuitive applications of Multilevel Regression and Poststratification (MRP). Users can apply the method to a variety of datasets, from electronic health records to sample survey data, through an end-to-end Bayesian data analysis workflow. The package provides robust tools for data cleaning, exploratory analysis, flexible model building, and insightful result visualization. For more details, see Si et al. (2020) <https://www150.statcan.gc.ca/n1/en/pub/12-001-x/2020002/article/00003-eng.pdf?st=iF1_Fbrh> and Si (2025) <doi:10.1214/24-STS932>.

This package provides a simple interface to recursively list files from a directory, filter them using a regular expression, read their contents, and extract lines that match a user-defined pattern. The package returns a dataframe containing the matched lines, their line numbers, file paths, and the corresponding matched substrings. Designed for quick code base exploration, log inspection, or any use case involving pattern-based file and line filtering.

Design a Bayesian seamless multi-arm biomarker-enriched phase II/III design with the survival endpoint with allowing sample size re-estimation. James M S Wason, Jean E Abraham, Richard D Baird, Ioannis Gournaris, Anne-Laure Vallier, James D Brenton, Helena M Earl, Adrian P Mander (2015) <doi:10.1038/bjc.2015.278>. Guosheng Yin, Nan Chen, J. Jack Lee (2018) <doi:10.1007/s12561-017-9199-7>. Ying Yuan, Beibei Guo, Mark Munsell, Karen Lu, Amir Jazaeri (2016) <doi:10.1002/sim.6971>.

This package provides functions to speed up work flow for hydrological analysis. Focused on Australian climate data (SILO climate data), hydrological models (eWater Source) and in particular South Australia (<https://water.data.sa.gov.au> hydrological data).

This package provides statistical tools for testing first-order separability in spatio-temporal point processes, that is, assessing whether the spatio-temporal intensity function can be expressed as the product of spatial and temporal components. The package implements several hypothesis tests, including exact and asymptotic methods for Poisson and non-Poisson processes. Methods include global envelope tests, chi-squared type statistics, and a novel Hilbert-Schmidt independence criterion (HSIC) test, all with both block and pure permutation procedures. Simulation studies and real world examples, including the 2001 UK foot and mouth disease outbreak data, illustrate the utility of the proposed methods. The package contains all simulation studies and applications presented in Ghorbani et al. (2021) <doi:10.1016/j.csda.2021.107245> and Ghorbani et al. (2025) <doi:10.1007/s11749-025-00972-y>.

An outcome-guided algorithm is developed to identify clusters of samples with similar characteristics and survival rate. The algorithm first builds a random forest and then defines distances between samples based on the fitted random forest. Given the distances, we can apply hierarchical clustering algorithms to define clusters. Details about this method is described in <https://github.com/luyouepiusf/SurvivalClusteringTree>.

Create correlation networks using St. Nicolas House Analysis ('SNHA'). The package can be used for visualizing multivariate data similar to Principal Component Analysis or Multidimensional Scaling using a ranking approach. In contrast to MDS and PCA', SNHA uses a network approach to explore interacting variables. For details see Hermanussen et. al. 2021', <doi:10.3390/ijerph18041741>.

This package provides a computational framework for analyzing mutations in immunoglobulin (Ig) sequences. Includes methods for Bayesian estimation of antigen-driven selection pressure, mutational load quantification, building of somatic hypermutation (SHM) models, and model-dependent distance calculations. Also includes empirically derived models of SHM for both mice and humans. Citations: Gupta and Vander Heiden, et al (2015) <doi:10.1093/bioinformatics/btv359>, Yaari, et al (2012) <doi:10.1093/nar/gks457>, Yaari, et al (2013) <doi:10.3389/fimmu.2013.00358>, Cui, et al (2016) <doi:10.4049/jimmunol.1502263>.

Sparse redundancy analysis for high dimensional (biomedical) data. Directional multivariate analysis to express the maximum variance in the predicted data set by a linear combination of variables of the predictive data set. Implemented in a partial least squares framework, for more details see Csala et al. (2017) <doi:10.1093/bioinformatics/btx374>.

Fits time trend models for routine disease surveillance tasks and returns probability distributions for a variety of quantities of interest, including age-standardized rates, period and cumulative percent change, and measures of health inequality. The models are appropriate for count data such as disease incidence and mortality data, employing a Poisson or binomial likelihood and the first-difference (random-walk) prior for unknown risk. Optionally add a covariance matrix for multiple, correlated time series models. Inference is completed using Markov chain Monte Carlo via the Stan modeling language. References: Donegan, Hughes, and Lee (2022) <doi:10.2196/34589>; Stan Development Team (2021) <https://mc-stan.org>; Theil (1972, ISBN:0-444-10378-3).

Model age schedules of mortality, nqx, suitable for a life table. This package implements the SVD-Comp mortality model indexed by either child or child/adult mortality. Given input value(s) of either 5q0 or (5q0, 45q15), the qx() function generates single-year 1qx or 5-year 5qx conditional age-specific probabilities of dying. See Clark (2016) <doi:10.48550/arXiv.1612.01408> and Clark (2019) <doi:10.1007/s13524-019-00785-3>.

Efficient implementations for Sorted L-One Penalized Estimation (SLOPE): generalized linear models regularized with the sorted L1-norm (Bogdan et al. 2015). Supported models include ordinary least-squares regression, binomial regression, multinomial regression, and Poisson regression. Both dense and sparse predictor matrices are supported. In addition, the package features predictor screening rules that enable fast and efficient solutions to high-dimensional problems.

Offers a fast algorithm for fitting solution paths of sparse SVM models with lasso or elastic-net regularization. Reference: Congrui Yi and Jian Huang (2017) <doi:10.1080/10618600.2016.1256816>.

This package provides functions are provided for the density function, distribution function, quantiles and random number generation for the skew hyperbolic t-distribution. There are also functions that fit the distribution to data. There are functions for the mean, variance, skewness, kurtosis and mode of a given distribution and to calculate moments of any order about any centre. To assess goodness of fit, there are functions to generate a Q-Q plot, a P-P plot and a tail plot.