This package performs the permutation test using difference in the restricted mean survival time (RMST) between groups as a summary measure of the survival time distribution. When the sample size is less than 50 per group, it has been shown that there is non-negligible inflation of the type I error rate in the commonly used asymptotic test for the RMST comparison. Generally, permutation tests can be useful in such a situation. However, when we apply the permutation test for the RMST comparison, particularly in small sample situations, there are some cases where the survival function in either group cannot be defined due to censoring in the permutation process. Horiguchi and Uno (2020) <doi:10.1002/sim.8565> have examined six workable solutions to handle this numerical issue. It performs permutation tests with implementation of the six methods outlined in the paper when the numerical issue arises during the permutation process. The result of the asymptotic test is also provided for a reference.

This package provides a collection of functions to perform Detrended Fluctuation Analysis (DFA exponent), GUEDES et al. (2019) <doi:10.1016/j.physa.2019.04.132> , Detrended cross-correlation coefficient (RHODCCA), GUEDES & ZEBENDE (2019) <doi:10.1016/j.physa.2019.121286>, DMCA cross-correlation coefficient and Detrended multiple cross-correlation coefficient (DMC), GUEDES & SILVA-FILHO & ZEBENDE (2018) <doi:10.1016/j.physa.2021.125990>, both with sliding windows approach.

This package provides some basic routines for simulating a clinical trial. The primary intent is to provide some tools to generate trial simulations for trials with time to event outcomes. Piecewise exponential failure rates and piecewise constant enrollment rates are the underlying mechanism used to simulate a broad range of scenarios such as those presented in Lin et al. (2020) <doi:10.1080/19466315.2019.1697738>. However, the basic generation of data is done using pipes to allow maximum flexibility for users to meet different needs.

It's my experience that working with shiny is intuitive once you're into it, but can be quite daunting at first. Several common mistakes are fairly predictable, and therefore we can control for these. The functions in this package help match up the assets listed in the UI and the SERVER files, and Visualize the ad hoc structure of the shiny App.

This package provides a shiny interface for a simpler use of the sbm R package. It also contains useful functions to easily explore the sbm package results. With this package you should be able to use the stochastic block model without any knowledge in R, get automatic reports and nice visuals, as well as learning the basic functions of sbm'.

I provide functions to calculate Gross Primary Productivity, Net Ecosystem Production, and Ecosystem Respiration from single station diurnal Oxygen curves.

This package provides functionality for simulating data generation processes across various spatial regression models, conceptually aligned with the dgp module of the Python library spreg <https://pysal.org/spreg/api.html#dgp>.

Implementation of single-source capture-recapture methods for population size estimation using zero-truncated, zero-one truncated and zero-truncated one-inflated Poisson, Geometric and Negative Binomial regression as well as Zelterman's and Chao's regression. Package includes point and interval estimators for the population size with variances estimated using analytical or bootstrap method. Details can be found in: van der Heijden et all. (2003) <doi:10.1191/1471082X03st057oa>, Böhning and van der Heijden (2019) <doi:10.1214/18-AOAS1232>, Böhning et al. (2020) Capture-Recapture Methods for the Social and Medical Sciences or Böhning and Friedl (2021) <doi:10.1007/s10260-021-00556-8>.

Calculates parameters of the seawater carbonate system and assists the design of ocean acidification perturbation experiments.

The saemix package implements the Stochastic Approximation EM algorithm for parameter estimation in (non)linear mixed effects models. It (i) computes the maximum likelihood estimator of the population parameters, without any approximation of the model (linearisation, quadrature approximation,...), using the Stochastic Approximation Expectation Maximization (SAEM) algorithm, (ii) provides standard errors for the maximum likelihood estimator (iii) estimates the conditional modes, the conditional means and the conditional standard deviations of the individual parameters, using the Hastings-Metropolis algorithm (see Comets et al. (2017) <doi:10.18637/jss.v080.i03>). Many applications of SAEM in agronomy, animal breeding and PKPD analysis have been published by members of the Monolix group. The full PDF documentation for the package including references about the algorithm and examples can be downloaded on the github of the IAME research institute for saemix': <https://github.com/iame-researchCenter/saemix/blob/7638e1b09ccb01cdff173068e01c266e906f76eb/docsaem.pdf>.

Omics data (e.g. transcriptomics, proteomics, metagenomics...) offer a detailed and multi-dimensional perspective on the molecular components and interactions within complex biological (eco)systems. Analyzing these data requires adapted procedures, which are implemented as steps according to the recipes package.

Calculates the power and sample size based on the difference in Restricted Mean Survival Time.

Statistical pattern recognition and dating using archaeological artefacts assemblages. Package of statistical tools for archaeology. hclustcompro()/perioclust(): Bellanger Lise, Coulon Arthur, Husi Philippe (2021, ISBN:978-3-030-60103-4). mapclust(): Bellanger Lise, Coulon Arthur, Husi Philippe (2021) <doi:10.1016/j.jas.2021.105431>. seriograph(): Desachy Bruno (2004) <doi:10.3406/pica.2004.2396>. cerardat(): Bellanger Lise, Husi Philippe (2012) <doi:10.1016/j.jas.2011.06.031>.

This package provides an S4 class for representing and interacting with sparse plus rank matrices. At the moment the implementation is quite spare, but the plan is eventually subclass Matrix objects.

Functions, classes and methods for time series modelling with ARIMA and related models. The aim of the package is to provide consistent interface for the user. For example, a single function autocorrelations() computes various kinds of theoretical and sample autocorrelations. This is work in progress, see the documentation and vignettes for the current functionality. Function sarima() fits extended multiplicative seasonal ARIMA models with trends, exogenous variables and arbitrary roots on the unit circle, which can be fixed or estimated (for the algebraic basis for this see <doi:10.48550/arXiv.2208.05055>, a paper on the methodology is being prepared).

Sensitivity analysis for trials with irregular and informative assessment times, based on a new influence function-based, augmented inverse intensity-weighted estimator.

Determining potential output and the output gap - two inherently unobservable variables - is a major challenge for macroeconomists. sectorgap features a flexible modeling and estimation framework for a multivariate Bayesian state space model identifying economic output fluctuations consistent with subsectors of the economy. The proposed model is able to capture various correlations between output and a set of aggregate as well as subsector indicators. Estimation of the latent states and parameters is achieved using a simple Gibbs sampling procedure and various plotting options facilitate the assessment of the results. For details on the methodology and an illustrative example, see Streicher (2024) <https://www.research-collection.ethz.ch/handle/20.500.11850/653682>.

The focus is on simulating and modeling families with founders drawn from a structured population (for example, with different ancestries or other potentially non-family relatedness), in contrast to traditional pedigree analysis that treats all founders as equally unrelated. Main function simulates a random pedigree for many generations, avoiding close relatives, pairing closest individuals according to a 1D geography and their randomly-drawn sex, and with variable children sizes to result in a target population size per generation. Auxiliary functions calculate kinship matrices, admixture matrices, and draw random genotypes across arbitrary pedigree structures starting from the corresponding founder values. The code is built around the plink FAM table format for pedigrees. Described in Yao and Ochoa (2022) <doi:10.1101/2022.03.25.485885>.

This package provides extensions for package sitree for allometric variables, growth, mortality, recruitment, management, tree removal and external modifiers functions.

S4 class wrappers for the ODBC and Pool DBI connection, also provides some utilities to paste small datasets to clipboard, rename columns. It is used by the package stacomiR for connections to the database. Development versions of stacomiR are available in R-forge.

Fit design-based linear and logistic elastic nets with complex survey data considering the sampling design when defining training and test sets using replicate weights. Methods implemented in this package are described in: A. Iparragirre, T. Lumley, I. Barrio, I. Arostegui (2024) <doi:10.1002/sta4.578>.

Allows TailwindCSS to be used in Shiny apps with just-in-time compiling, custom css with @apply directive, and custom tailwind configurations.

This package provides a simple, light, and robust interface between R and the Scryfall card data API <https://scryfall.com/docs/api>.

Provide a workflow to jointly embed chromatin accessibility peaks and expressed genes into a shared low-dimensional space using paired single-cell ATAC-seq (scATAC-seq) and single-cell RNA-seq (scRNA-seq) data. It integrates regulatory relationships among peak-peak interactions (via Cicero'), peak-gene interactions (via Lasso, random forest, and XGBoost), and gene-gene interactions (via principal component regression). With the input of paired scATAC-seq and scRNA-seq data matrices, it assigns a low-dimensional feature vector to each gene and peak. Additionally, it supports the reconstruction of gene-gene network with low-dimensional projections (via epsilon-NN) and then the comparison of the networks of two conditions through manifold alignment implemented in scTenifoldNet'. See <doi:10.1093/bioinformatics/btaf483> for more details.