An implementation of popular evaluation metrics that are commonly used in survival prediction including Concordance Index, Brier Score, Integrated Brier Score, Integrated Square Error, Integrated Absolute Error and Mean Absolute Error. For a detailed information, see (Ishwaran H, Kogalur UB, Blackstone EH and Lauer MS (2008) <doi:10.1214/08-AOAS169>) , (Moradian H, Larocque D and Bellavance F (2017) <doi:10.1007/s10985-016-9372-1>), (Hanpu Zhou, Hong Wang, Sizheng Wang and Yi Zou (2023) <doi:10.32614/rj-2023-009>) for different evaluation metrics.

Perform biomarker evaluation and comparison in terms of specificity at a controlled sensitivity level, or sensitivity at a controlled specificity level. Point estimation and exact bootstrap of Huang, Parakati, Patil, and Sanda (2023) <doi:10.5705/ss.202021.0020> for the one- and two-biomarker problems are implemented.

This package implements the Smoothness-Penalized Deconvolution method for estimating a probability density under measurement error of Kent and Ruppert (2023) <doi:10.1080/01621459.2023.2259028>. The estimator is formed by computing a histogram of the error-contaminated data, and then finding an estimate that minimizes a reconstruction error plus a smoothness-inducing penalty term. The primary function, sped(), takes the data and error distribution, and returns the estimator as a function.

Handle POST requests on a custom path (e.g., /ingress) inside the same shiny HTTP server using user interface functions and HTTP responses. Expose latest payload as a reactive and provide helpers for query parameters.

This package provides a tool for producing synthetic versions of microdata containing confidential information so that they are safe to be released to users for exploratory analysis. The key objective of generating synthetic data is to replace sensitive original values with synthetic ones causing minimal distortion of the statistical information contained in the data set. Variables, which can be categorical or continuous, are synthesised one-by-one using sequential modelling. Replacements are generated by drawing from conditional distributions fitted to the original data using parametric or classification and regression trees models. Data are synthesised via the function syn() which can be largely automated, if default settings are used, or with methods defined by the user. Optional parameters can be used to influence the disclosure risk and the analytical quality of the synthesised data. For a description of the implemented method see Nowok, Raab and Dibben (2016) <doi:10.18637/jss.v074.i11>. Functions to assess identity and attribute disclosure for the original and for the synthetic data are included in the package, and their use is illustrated in a vignette on disclosure (Practical Privacy Metrics for Synthetic Data).

To meet the needs of statistical power calculation for stepped wedge cluster randomized trials, we developed this software. Different parameters can be specified by users for different scenarios, including: cross-sectional and cohort designs, binary and continuous outcomes, marginal (GEE) and conditional models (mixed effects model), three link functions (identity, log, logit links), with and without time effects (the default specification assumes no-time-effect) under exchangeable, nested exchangeable and block exchangeable correlation structures. Unequal numbers of clusters per sequence are also allowed. The methods included in this package: Zhou et al. (2020) <doi:10.1093/biostatistics/kxy031>, Li et al. (2018) <doi:10.1111/biom.12918>. Supplementary documents can be found at: <https://ysph.yale.edu/cmips/research/software/study-design-power-calculation/swdpwr/>. The Shiny app for swdpwr can be accessed at: <https://jiachenchen322.shinyapps.io/swdpwr_shinyapp/>. The package also includes functions that perform calculations for the intra-cluster correlation coefficients based on the random effects variances as input variables for continuous and binary outcomes, respectively.

This package provides methods for the analysis of signed networks. This includes several measures for structural balance as introduced by Cartwright and Harary (1956) <doi:10.1037/h0046049>, blockmodeling algorithms from Doreian (2008) <doi:10.1016/j.socnet.2008.03.005>, various centrality indices, and projections of signed two-mode networks introduced by Schoch (2020) <doi:10.1080/0022250X.2019.1711376>.

This package implements the methodological developments found in Hermes (2025) <doi:10.48550/arXiv.2503.02786>, and allows for the statistical modeling of data consisting of multiple users that provide an ordinal rating for one or multiple items.

This package contains functions that help to determine event boundaries in event segmentation experiments by bootstrapping a critical segmentation magnitude under the null hypothesis that all key presses were randomly distributed across the experiment. Segmentation magnitude is defined as the sum of Gaussians centered at the times of the segmentation key presses performed by the participants. Within a participant, the maximum of the overlaid Gaussians is used to prevent an excessive influence of a single participant on the overall outcome (e.g. if a participant is pressing the key multiple times in succession). Further functions are included, such as plotting the results.

This package provides a pipeline that can process single or multiple Single Cell RNAseq samples primarily specializes in Clustering and Dimensionality Reduction. Meanwhile we use common cell type marker genes for T cells, B cells, Myeloid cells, Epithelial cells, and stromal cells (Fiboblast, Endothelial cells, Pericyte, Smooth muscle cells) to visualize the Seurat clusters, to facilitate labeling them by biological names. Once users named each cluster, they can evaluate the quality of them again and find the de novo marker genes also.

This package provides tools to calculate the alpha parameter of the Weibull distribution, given beta and the age-specific fertility of a species, so that the population remains stable and stationary. Methods are inspired by "Survival profiles from linear models versus Weibull models: Estimating stable and stationary population structures for Pleistocene large mammals" (Martà n-González et al. 2019) <doi:10.1016/j.jasrep.2019.03.031>.

This package provides a collection of procedures for analysing, visualising, and managing single-case data. These include regression models (multilevel, multivariate, bayesian), between case standardised mean difference, overlap indices ('PND', PEM', PAND', PET', tau-u', IRD', baseline corrected tau', CDC'), and randomization tests. Data preparation functions support outlier detection, handling missing values, scaling, and custom transformations. An export function helps to generate html, word, and latex tables in a publication friendly style. A shiny app allows to use scan in a graphical user interface. More details can be found in the online book Analyzing single-case data with R and scan', Juergen Wilbert (2025) <https://jazznbass.github.io/scan-Book/>.

This package provides drop-in replacements for functions from the stringr package, with the same user interface. These functions have no external dependencies and can be copied directly into your package code using the staticimports package.

Data on standard load profiles from the German Association of Energy and Water Industries (BDEW Bundesverband der Energie- und Wasserwirtschaft e.V.) in a tidy format. The data and methodology are described in VDEW (1999), "Repräsentative VDEW-Lastprofile", <https://www.bdew.de/media/documents/1999_Repraesentative-VDEW-Lastprofile.pdf>. The package also offers an interface for generating a standard load profile over a user-defined period. For the algorithm, see VDEW (2000), "Anwendung der Repräsentativen VDEW-Lastprofile step-by-step", <https://www.bdew.de/media/documents/2000131_Anwendung-repraesentativen_Lastprofile-Step-by-step.pdf>.

Compute centrographic statistics (central points, standard distance, standard deviation ellipse, standard deviation box) for observations taken at point locations in 2D or 3D. The sfcentral library was inspired in aspace package but conceived to be used in a spatial tidyverse context.

Generalized additive models under shape constraints on the component functions of the linear predictor. Models can include multiple shape-constrained (univariate and bivariate) and unconstrained terms. Routines of the package mgcv are used to set up the model matrix, print, and plot the results. Multiple smoothing parameter estimation by the Generalized Cross Validation or similar. See Pya and Wood (2015) <doi:10.1007/s11222-013-9448-7> for an overview. A broad selection of shape-constrained smoothers, linear functionals of smooths with shape constraints, and Gaussian models with AR1 residuals.

Many complex diseases are known to be affected by the interactions between genetic variants and environmental exposures beyond the main genetic and environmental effects. Existing Bayesian methods for gene-environment (GÃ E) interaction studies are challenged by the high-dimensional nature of the study and the complexity of environmental influences. We have developed a novel and powerful semi-parametric Bayesian variable selection method that can accommodate linear and nonlinear GÃ E interactions simultaneously (Ren et al. (2020) <doi:10.1002/sim.8434>). Furthermore, the proposed method can conduct structural identification by distinguishing nonlinear interactions from main effects only case within Bayesian framework. Spike-and-slab priors are incorporated on both individual and group level to shrink coefficients corresponding to irrelevant main and interaction effects to zero exactly. The Markov chain Monte Carlo algorithms of the proposed and alternative methods are efficiently implemented in C++.

Develops a framework for fisheries stock assessment simulation testing with Stock Synthesis (SS) as described in Anderson et al. (2014) <doi:10.1371/journal.pone.0092725>.

This package provides an interface to search, read, query, and retrieve metadata for datasets hosted on Socrata open data portals. Supports all Socrata data types, including spatial data returned as sf objects.

An Object-oriented Framework for Geostatistical Modeling in S+ containing functions for variogram estimation, variogram fitting and kriging as well as some plot functions. Written entirely in S, therefore works only for small data sets in acceptable computing time.

This package provides functions and datasets from Jones, O.D., R. Maillardet, and A.P. Robinson. 2014. An Introduction to Scientific Programming and Simulation, Using R. 2nd Ed. Chapman And Hall/CRC.

Identify and understand clusters of points (typically representing the locations of places or events) stored in simple-features (SF) objects. This is useful for analysing, for example, hot-spots of crime events. The package emphasises producing results from point SF data in a single step using reasonable default values for all other arguments, to aid rapid data analysis by users who are starting out. Functions available include kernel density estimation (for details, see Yip (2020) <doi:10.22224/gistbok/2020.1.12>), analysis of spatial association (Getis and Ord (1992) <doi:10.1111/j.1538-4632.1992.tb00261.x>) and hot-spot classification (Chainey (2020) ISBN:158948584X).

This package provides a collection of functions to deal with spatial and spatiotemporal autoregressive conditional heteroscedasticity (spatial ARCH and GARCH models) by Otto, Schmid, Garthoff (2018, Spatial Statistics) <doi:10.1016/j.spasta.2018.07.005>: simulation of spatial ARCH-type processes (spARCH, log/exponential-spARCH, complex-spARCH); quasi-maximum-likelihood estimation of the parameters of spARCH models and spatial autoregressive models with spARCH disturbances, diagnostic checks, visualizations.

This software is useful for loading .fasta or .gbk files, and for retrieving sequences from GenBank dataset <https://www.ncbi.nlm.nih.gov/genbank/>. This package allows to detect differences or asymmetries based on nucleotide composition by using local linear kernel smoothers. Also, it is possible to draw inference about critical points (i. e. maximum or minimum points) related with the derivative curves. Additionally, bootstrap methods have been used for estimating confidence intervals and speed computational techniques (binning techniques) have been implemented in seq2R'.