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This package provides a subgroup identification method for precision medicine based on quantitative objectives. This method can handle continuous, binary and survival endpoint for both prognostic and predictive case. For the predictive case, the method aims at identifying a subgroup for which treatment is better than control by at least a pre-specified or auto-selected constant. For the prognostic case, the method aims at identifying a subgroup that is at least better than a pre-specified/auto-selected constant. The derived signature is a linear combination of predictors, and the selected subgroup are subjects with the signature > 0. The false discover rate when no true subgroup exists is controlled at a user-specified level.
Get started with new projects by dropping a skeleton of a new project into a new or existing directory, initialise git repositories, and create reproducible environments with the renv package. The package allows for dynamically named files, folders, file content, as well as the functionality to drop individual template files into existing projects.
Enables the ability to change or flash the title of the browser window during a shiny session.
Efficient R package for latent class analysis of recurrent events, based on the semiparametric multiplicative intensity model by Zhao et al. (2022) <doi:10.1111/rssb.12499>. SLCARE returns estimates for non-functional model parameters along with the associated variance estimates and p-values. Visualization tools are provided to depict the estimated functional model parameters and related functional quantities of interest. SLCARE also delivers a model checking plot to help assess the adequacy of the fitted model.
This package implements several functions that automates the cleaning and spell-checking of text data. Also converges, finalizes, removes plurals and continuous strings, and puts text data in binary format for semantic network analysis. Uses the SemNetDictionaries package to make the cleaning process more accurate, efficient, and reproducible.
Linkage disequilibrium visualizations of up to several hundreds of single nucleotide polymorphisms (SNPs), annotated with chromosomic positions and gene names. Two types of plots are available for small numbers of SNPs (<40) and for large numbers (tested up to 500). Both can be extended by combining other ggplots, e.g. association studies results, and functions enable to directly visualize the effect of SNP selection methods, as minor allele frequency filtering and TagSNP selection, with a second correlation heatmap. The SNPs correlations are computed on Genotype Data objects from the GWASTools package using the SNPRelate package, and the plots are customizable ggplot2 and gtable objects and are annotated using the biomaRt package. Usage is detailed in the vignette with example data and results from up to 500 SNPs of 1,200 scans are in Charlon T. (2019) <doi:10.13097/archive-ouverte/unige:161795>.
Generate simulated datasets from an initial underlying distribution and apply transformations to obtain realistic data. Implements the NORTA (Normal-to-anything) approach from Cario and Nelson (1997) and other data generating mechanisms. Simple network visualization tools are provided to facilitate communicating the simulation setup.
This package provides a complete analysis pipeline for the WHO STEPwise Approach to NCD Risk Factor Surveillance (STEPS) as described in Riley et al. (2016) <doi:10.2105/AJPH.2015.302962>. Imports raw survey data ('CSV', Excel', Stata', SPSS'), applies WHO-standard cleaning and recoding, sets up complex survey designs, computes all standard NCD indicators (tobacco, alcohol, diet, physical activity, anthropometry, blood pressure, biochemical), and generates publication-ready tables, visualisations, and Word'/'HTML reports (fact sheet, data book, country report).
New tools for post-selection inference, for use with forward stepwise regression, least angle regression, the lasso, and the many means problem. The lasso function implements Gaussian, logistic and Cox survival models.
Sequential Kalman filter for scalable online changepoint detection by temporally correlated data. It enables fast single and multiple change points with missing values. See the reference: Hanmo Li, Yuedong Wang, Mengyang Gu (2023), <arXiv:2310.18611>.
Spatiotemporal individual-level model of seasonal infectious disease transmission within the Susceptible-Exposed-Infectious-Recovered-Susceptible (SEIRS) framework are applied to model seasonal infectious disease transmission. This package employs a likelihood based Monte Carlo Expectation Conditional Maximization (MCECM) algorithm for estimating model parameters. In addition to model fitting and parameter estimation, the package offers functions for calculating AIC using real pandemic data and conducting simulation studies customized to user-specified model configurations.
This package provides two main functionalities. 1 - Given a system of simultaneous equation, it decomposes the matrix of coefficients weighting the endogenous variables into three submatrices: one includes the subset of coefficients that have a causal nature in the model, two include the subset of coefficients that have a interdependent nature in the model, either at systematic level or induced by the correlation between error terms. 2 - Given a decomposed model, it tests for the significance of the interdependent relationships acting in the system, via Maximum likelihood and Wald test, which can be built starting from the function output. For theoretical reference see Faliva (1992) <doi:10.1007/BF02589085> and Faliva and Zoia (1994) <doi:10.1007/BF02589041>.
This package provides functionality for simulating data generation processes across various spatial regression models, conceptually aligned with the dgp module of the Python library spreg <https://pysal.org/spreg/api.html#dgp>.
This package performs simulations of binary spatial raster data using the Ising model (Ising (1925) <doi:10.1007/BF02980577>; Onsager (1944) <doi:10.1103/PhysRev.65.117>). It allows to set a few parameters that represent internal and external pressures, and the number of simulations (Stepinski and Nowosad (2023) <doi:10.1098/rsos.231005>).
Starting from a Regression Model, it provides a stepwise procedure to select the linear predictor.
This package provides interface to the Spectator Earth API <https://api.spectator.earth/>, mainly for obtaining the acquisition plans and satellite overpasses for Sentinel-1, Sentinel-2, Landsat-8 and Landsat-9 satellites. Current position and trajectory can also be obtained for a much larger set of satellites. It is also possible to search the archive for available images over the area of interest for a given (past) period, get the URL links to download the whole image tiles, or alternatively to download the image for just the area of interest based on selected spectral bands.
This package provides a function that behaves nearly as base::source() but implements a caching mechanism on disk, project based. It allows to quasi source() R scripts that gather data but can fail or consume to much time to respond even if nothing new is expected. It comes with tools to check and execute on demand or when cache is invalid the script.
Facilitates probabilistic record linkage between infectious disease surveillance datasets (notifiable disease registers, outbreak line-lists), vaccination registries, and hospitalization records using methods based on Fellegi and Sunter (1969) <doi:10.1080/01621459.1969.10501049> and Sayers et al. (2016) <doi:10.1093/ije/dyv322>. The package provides core functions for data preparation, linkage, and analysis: clean_the_nest() standardizes variable names and formats across heterogeneous datasets; murmuration() performs machine learning-based record linkage using blocking variables and similarity metrics; molting() deidentifies datasets for secure sharing; homing() re-identifies previously deidentified datasets; plumage() identifies and categorizes comorbidities; and preening() creates analysis-ready variables including age categories and temporal groupings. Designed for epidemiological research linking acute and post-acute disease outcomes to vaccination status and healthcare utilization. Supports multiple linkage scenarios including case-to-vaccination, case-to-hospitalization, and event-based vaccination status determination (e.g., outbreak attendees, flight passengers, exposure site visitors).
This package creates an S4 class "SSM" and defines functions for fitting smooth supersaturated models, a polynomial model with spline-like behaviour. Functions are defined for the computation of Sobol indices for sensitivity analysis and plotting the main effects using FANOVA methods. It also implements the estimation of the SSM metamodel error using a GP model with a variety of defined correlation functions.
Facilitate the evaluation of forecasts in a convenient framework based on data.table. It allows user to to check their forecasts and diagnose issues, to visualise forecasts and missing data, to transform data before scoring, to handle missing forecasts, to aggregate scores, and to visualise the results of the evaluation. The package mostly focuses on the evaluation of probabilistic forecasts and allows evaluating several different forecast types and input formats. Find more information about the package in the Vignettes as well as in the accompanying paper, <doi:10.48550/arXiv.2205.07090>.
Set of functions that access information about deputies and votings in Polish diet from webpage <http://www.sejm.gov.pl>. The package was developed as a result of an internship in MI2 Group - <http://mi2.mini.pw.edu.pl>, Faculty of Mathematics and Information Science, Warsaw University of Technology.
Interfaces the stepcount Python module <https://github.com/OxWearables/stepcount> to estimate step counts and other activities from accelerometry data.
Data simulator including genotype, phenotype, pedigree, selection and reproduction in R. It simulates most of reproduction process of animals or plants and provides data for GS (Genomic Selection), GWAS (Genome-Wide Association Study), and Breeding. For ADI model, please see Kao C and Zeng Z (2002) <doi:10.1093/genetics/160.3.1243>. For build.cov, please see B. D. Ripley (1987) <ISBN:9780470009604>.
This package performs variable selection using the structured screen-and-select (S3VS) framework in linear models, generalized linear models with binary data, and survival models such as the Cox model and accelerated failure time (AFT) model.