Wraps the Ollama <https://ollama.com> API, which can be used to communicate with generative large language models locally.

Loads Axon Binary Files (both ABF and ABF2') created by Axon Instruments/Molecular Devices software such as pClamp'.

This package provides a friendly, object oriented API for creating PowerPoint slide decks in R.

An HTTP API client for Lemmy (<https://github.com/LemmyNet/lemmy>) in R. Code and documentation are generated from the official JavaScript client source (<https://github.com/LemmyNet/lemmy-js-client>).

This package performs goodness of fits tests for both high and low-dimensional linear models. It can test for a variety of model misspecifications including nonlinearity and heteroscedasticity. In addition one can test the significance of potentially large groups of variables, and also produce p-values for the significance of individual variables in high-dimensional linear regression.

Implementation of the methods described in the paper with the above title: Langsrud, Ã . (2019) <doi:10.1007/s11222-018-9848-9>. The package can be used to generate synthetic or hybrid continuous microdata, and the relationship to the original data can be controlled in several ways. A function for replacing suppressed tabular cell frequencies with decimal numbers is included.

Fits measurement error models using Monte Carlo Expectation Maximization (MCEM). For specific details on the methodology, see: Greg C. G. Wei & Martin A. Tanner (1990) A Monte Carlo Implementation of the EM Algorithm and the Poor Man's Data Augmentation Algorithms, Journal of the American Statistical Association, 85:411, 699-704 <doi:10.1080/01621459.1990.10474930> For more examples on measurement error modelling using MCEM, see the RMarkdown vignette: "'refitME R-package tutorial".

Processes and visualizes the output of complex phylogenetic analyses from the RevBayes phylogenetic graphical modeling software.

Interface to access data via the United States Department of Agriculture's National Agricultural Statistical Service (NASS) Quick Stats web API <https://quickstats.nass.usda.gov/api/>. Convenience functions facilitate building queries based on available parameters and valid parameter values. This product uses the NASS API but is not endorsed or certified by NASS.

This package provides an interface with the Wildbook mark-recapture ecological database framework. It helps users to pull data from the Wildbook framework and format data for further analysis with mark-recapture applications like Program MARK (which can be accessed via the RMark package in R'). Further information on the Wildbook framework is available at: <http://www.wildbook.org/doku.php>.

Fits standard and random effects latent class models. The single level random effects model is described in Qu et al <doi:10.2307/2533043> and the two level random effects model in Beath and Heller <doi:10.1177/1471082X0800900302>. Examples are given for their use in diagnostic testing.

Estimating repeatability (intra-class correlation) from Gaussian, binary, proportion and Poisson data.

Calculate common survey data quality indicators for multi-item scales and matrix questions. Currently supports the calculation of response style indicators and response distribution indicators. For an overview on response quality indicators see Bhaktha N, Henning S, Clemens L (2024). Characterizing response quality in surveys with multi-item scales: A unified framework <https://osf.io/9gs67/>.

Mediation analysis for multiple mediators by penalized structural equation models with different types of penalties depending on whether there are multiple mediators and only one exposure and one outcome variable (using sparse group lasso) or multiple exposures, multiple mediators, and multiple outcome variables (using lasso, L1, penalties).

R Markdown output formats based on JavaScript libraries such as Scrollama (<https://github.com/russellsamora/scrollama>) for storytelling.

Robust multivariate methods for high dimensional data including outlier detection (Filzmoser and Todorov (2013) <doi:10.1016/j.ins.2012.10.017>), robust sparse PCA (Croux et al. (2013) <doi:10.1080/00401706.2012.727746>, Todorov and Filzmoser (2013) <doi:10.1007/978-3-642-33042-1_31>), robust PLS (Todorov and Filzmoser (2014) <doi:10.17713/ajs.v43i4.44>), and robust sparse classification (Ortner et al. (2020) <doi:10.1007/s10618-019-00666-8>).

High resolution vector country boundaries derived from Natural Earth data, can be plotted in rworldmap.

Packed bar charts are a variation of treemaps for visualizing skewed data. The concept was introduced by Xan Gregg at JMP'.

An extension for roxygen2 to embed Shinylive applications in the package documentation.

This package provides methods to compute chemical similarity between two or more reactions and molecules. Allows masking of chemical substructures for weighted similarity computations. Uses packages rCDK and fingerprint for cheminformatics functionality. Methods for reaction similarity and sub-structure masking are as described in: Giri et al. (2015) <doi:10.1093/bioinformatics/btv416>.

Placental epigenetic clock to estimate aging based on gestational age using DNA methylation levels, so called placental epigenetic clock (PlEC). We developed a PlEC for the 2024 Placental Clock DREAM Challenge (<https://www.synapse.org/Synapse:syn59520082/wiki/628063>). Our PlEC achieved the top performance based on an independent test set. PlEC can be used to identify accelerated/decelerated aging of placenta for understanding placental dysfunction-related conditions, e.g., great obstetrical syndromes including preeclampsia, fetal growth restriction, preterm labor, preterm premature rupture of the membranes, late spontaneous abortion, and placental abruption. Detailed methodologies and examples are documented in our vignette, available at <https://herdiantrisufriyana.github.io/rplec/doc/placental_aging_analysis.html>.

Value-calibrated color ramps can be useful to emphasize patterns in data from complex distributions. Colors can be tied to specific values, and the association can be expanded into full color ramps that also include the relationship between colors and values. Such ramps can be used in a variety of cases when heatmap-type plots are necessary, including the visualization of vector and raster spatial data, such as topographies.

This package provides functions for simulating Markov chains using the Barker proposal to compute Markov chain Monte Carlo (MCMC) estimates of expectations with respect to a target distribution on a real-valued vector space. The Barker proposal, described in Livingstone and Zanella (2022) <doi:10.1111/rssb.12482>, is a gradient-based MCMC algorithm inspired by the Barker accept-reject rule. It combines the robustness of simpler MCMC schemes, such as random-walk Metropolis, with the efficiency of gradient-based methods, such as the Metropolis adjusted Langevin algorithm. The key function provided by the package is sample_chain(), which allows sampling a Markov chain with a specified target distribution as its stationary distribution. The chain is sampled by generating proposals and accepting or rejecting them using a Metropolis-Hasting acceptance rule. During an initial warm-up stage, the parameters of the proposal distribution can be adapted, with adapters available to both: tune the scale of the proposals by coercing the average acceptance rate to a target value; tune the shape of the proposals to match covariance estimates under the target distribution. As well as the default Barker proposal, the package also provides implementations of alternative proposal distributions, such as (Gaussian) random walk and Langevin proposals. Optionally, if BridgeStan's R interface <https://roualdes.us/bridgestan/latest/languages/r.html>, available on GitHub <https://github.com/roualdes/bridgestan>, is installed, then BridgeStan can be used to specify the target distribution to sample from.

The TRUST4 or MiXCR is used to identify the clonotypes. The goal of rTCRBCRr is to process the results from these clonotyping tools, and analyze the clonotype repertoire metrics based on chain names and IGH isotypes. The manuscript is still under preparation for publication for now. The references describing the methods in this package will be added later.