Constructs cell-typeâ specific gene regulatory networks from single-cell RNA-sequencing data. The method implements the SCORPION algorithm, which first aggregates individual cells into supercells and then applies PANDA (Passing Attributes between Networks for Data Assimilation) to infer transcription factorâ target regulatory relationships. It also provides statistical methods for differential edge analysis.

This package implements the Symphony single-cell reference building and query mapping algorithms and additional functions described in Kang et al <https://www.nature.com/articles/s41467-021-25957-x>.

This package implements an ensemble machine learning approach to predict the sporulation potential of metagenome-assembled genomes (MAGs) from uncultivated Firmicutes based on the presence/absence of sporulation-associated genes.

This package performs exact or approximate adaptive or nonadaptive Cochran-Mantel-Haenszel-Birch tests and sensitivity analyses for one or two 2x2xk tables in observational studies.

R bindings to SVD and eigensolvers (PROPACK, nuTRLan).

Utility functions that help with common base-R problems relating to lists. Lists in base-R are very flexible. This package provides functions to quickly and easily characterize types of lists. That is, to identify if all elements in a list are null, data.frames, lists, or fully named lists. Other functionality is provided for the handling of lists, such as the easy splitting of lists into equally sized groups, and the unnesting of data.frames within fully named lists.

The SAWNUTI algorithm performs sequence comparison for finite sequences of discrete events with non-uniform time intervals. Further description of the algorithm can be found in the paper: A. Murph, A. Flynt, B. R. King (2021). Comparing finite sequences of discrete events with non-uniform time intervals, Sequential Analysis, 40(3), 291-313. <doi:10.1080/07474946.2021.1940491>.

Support for reading/writing simple feature ('sf') spatial objects from/to Parquet files. Parquet files are an open-source, column-oriented data storage format from Apache (<https://parquet.apache.org/>), now popular across programming languages. This implementation converts simple feature list geometries into well-known binary format for use by arrow', and coordinate reference system information is maintained in a standard metadata format.

Basic statistical methods with some modifications for the course Statistical Methods at Federal University of Bahia (Brazil). All methods in this packages are explained in the text book of Montgomery and Runger (2010) <ISBN: 978-1-119-74635-5>.

This package provides a general purpose simulation-based power analysis API for routine and customized simulation experimental designs. The package focuses exclusively on Monte Carlo simulation experiment variants of (expected) prospective power analyses, criterion analyses, compromise analyses, sensitivity analyses, and a priori/post-hoc analyses. The default simulation experiment functions defined within the package provide stochastic variants of the power analysis subroutines in G*Power 3.1 (Faul, Erdfelder, Buchner, and Lang, 2009) <doi:10.3758/brm.41.4.1149>, along with various other parametric and non-parametric power analysis applications (e.g., mediation analyses) and support for Bayesian power analysis by way of Bayes factors or posterior probability evaluations. Additional functions for building empirical power curves, reanalyzing simulation information, and for increasing the precision of the resulting power estimates are also included, each of which utilize similar API structures. For further details see the associated publication in Chalmers (2025) <doi:10.3758/s13428-025-02787-z>.

This package implements the methodological developments found in Hermes, van Heerwaarden, and Behrouzi (2023) <doi:10.48550/arXiv.2308.04325>, and allows for the statistical modeling of asymmetric between-location effects, as well as within-location effects using spatial autoregressive graphical models. The package allows for the generation of spatial weight matrices to capture asymmetric effects for strip-type intercropping designs, although it can handle any type of spatial data commonly found in other sciences.

Easily analyze and visualize differences between samples (e.g., benchmark comparisons, nonresponse comparisons in surveys) on three levels. The comparisons can be univariate, bivariate or multivariate. On univariate level the variables of interest of a survey and a comparison survey (i.e. benchmark) are compared, by calculating one of several difference measures (e.g., relative difference in mean), and an average difference between the surveys. On bivariate level a function can calculate significant differences in correlations for the surveys. And on multivariate levels a function can calculate significant differences in model coefficients between the surveys of comparison. All of those differences can be easily plotted and outputted as a table. For more detailed information on the methods and example use see Rohr, B., Silber, H., & Felderer, B. (2024). Comparing the Accuracy of Univariate, Bivariate, and Multivariate Estimates across Probability and Nonprobability Surveys with Population Benchmarks. Sociological Methodology <doi:10.1177/00811750241280963>.

Estimation of various biodiversity indices and related (dis)similarity measures based on individual-based (abundance) data or sampling-unit-based (incidence) data taken from one or multiple communities/assemblages.

An introduction to several novel predictive variable selection methods for random forest. They are based on various variable importance methods (i.e., averaged variable importance (AVI), and knowledge informed AVI (i.e., KIAVI, and KIAVI2)) and predictive accuracy in stepwise algorithms. For details of the variable selection methods, please see: Li, J., Siwabessy, J., Huang, Z. and Nichol, S. (2019) <doi:10.3390/geosciences9040180>. Li, J., Alvarez, B., Siwabessy, J., Tran, M., Huang, Z., Przeslawski, R., Radke, L., Howard, F., Nichol, S. (2017). <DOI: 10.13140/RG.2.2.27686.22085>.

This package provides functions that wrap HTML Bootstrap components code to enable the design and layout of informative landing home pages for Shiny applications. This can lead to a better user experience for the users and writing less HTML for the developer.

Make graphical representations of single case data and transform graphical displays back to raw data, as discussed in Bulte and Onghena (2013) <doi:10.22237/jmasm/1383280020>. The package also includes tools for visually analyzing single-case data, by displaying central location, variability and trend.

Calculates sample size for various scenarios, such as sample size to estimate population proportion with stated absolute or relative precision, testing a single proportion with a reference value, to estimate the population mean with stated absolute or relative precision, testing single mean with a reference value and sample size for comparing two unpaired or independent means, comparing two paired means, the sample size For case control studies, estimating the odds ratio with stated precision, testing the odds ratio with a reference value, estimating relative risk with stated precision, testing relative risk with a reference value, testing a correlation coefficient with a specified value, etc. <https://www.academia.edu/39511442/Adequacy_of_Sample_Size_in_Health_Studies#:~:text=Determining%20the%20sample%20size%20for,may%20yield%20statistically%20inconclusive%20results.>.

This package implements an approach aimed at assessing the accuracy and effectiveness of raw scores obtained in scales that contain locally dependent items. The program uses as input the calibration (structural) item estimates obtained from fitting extended unidimensional factor-analytic solutions in which the existing local dependencies are included. Measures of reliability (Omega) and information are proposed at three levels: (a) total score, (b) bivariate-doublet, and (c) item-by-item deletion, and are compared to those that would be obtained if all the items had been locally independent. All the implemented procedures can be obtained from: (a) linear factor-analytic solutions in which the item scores are treated as approximately continuous, and (b) non-linear solutions in which the item scores are treated as ordered-categorical. A detailed guide can be obtained at the following url.

This package provides functions to retrieve, process, analyze, and quality-control marine physical, chemical, and biological data. The main focus is on Swedish monitoring data available through the SHARK database <https://shark.smhi.se/en/>, with additional API support for Nordic Microalgae <https://nordicmicroalgae.org/>, Dyntaxa <https://artfakta.se/>, World Register of Marine Species ('WoRMS') <https://www.marinespecies.org>, AlgaeBase <https://www.algaebase.org>, OBIS xylookup web service <https://iobis.github.io/xylookup/> and Intergovernmental Oceanographic Commission (IOC) - UNESCO databases on harmful algae <https://www.marinespecies.org/hab/> and toxins <https://toxins.hais.ioc-unesco.org/>.

This package provides option settings management that goes beyond R's default options function. With this package, users can define their own option settings manager holding option names, default values and (if so desired) ranges or sets of allowed option values that will be automatically checked. Settings can then be retrieved, altered and reset to defaults with ease. For R programmers and package developers it offers cloning and merging functionality which allows for conveniently defining global and local options, possibly in a multilevel options hierarchy. See the package vignette for some examples concerning functions, S4 classes, and reference classes. There are convenience functions to reset par() and options() to their factory defaults'.

Feature screening is a powerful tool in processing ultrahigh dimensional data. It attempts to screen out most irrelevant features in preparation for a more elaborate analysis. Xu and Chen (2014)<doi:10.1080/01621459.2013.879531> proposed an effective screening method SMLE, which naturally incorporates the joint effects among features in the screening process. This package provides an efficient implementation of SMLE-screening for high-dimensional linear, logistic, and Poisson models. The package also provides a function for conducting accurate post-screening feature selection based on an iterative hard-thresholding procedure and a user-specified selection criterion. Zang, Xu, and Burkett (2025)<doi:10.18637/jss.v115.i08>.

Calculates a modified Simplified Surface Energy Balance Index (SSEBI) and the Evaporative Fraction (EF) using geospatial raster data such as albedo and surface-air temperature difference (TSâ TA). The SSEBI is computed from albedo and TSâ TA to estimate surface moisture and evaporative dynamics, providing a robust assessment of surface dryness while accounting for atmospheric variations. Based on Roerink, Su, and Menenti (2000) <doi:10.1016/S1464-1909(99)00128-8>.

Enforcement of field types in lists. A drop-in tool to allow for dynamic input data that might be questionably parsed or cast to be coerced into the specific desired format in a reasonably performant manner.

Computationally efficient tools for high dimensional predictive modeling (regression and classification). SAM is short for sparse additive modeling, and adopts the computationally efficient basis spline technique. We solve the optimization problems by various computational algorithms including the block coordinate descent algorithm, fast iterative soft-thresholding algorithm, and newton method. The computation is further accelerated by warm-start and active-set tricks.