This package implements sparse Bayesian learning method for QTL mapping and genome-wide association studies.

This package implements user interfaces for log-linear models, Bayesian model averaging and Bayesian Dirichlet process mixture models. See McIntyre, Fellows, Gutreuter and Hladik (2022) <doi:10.2196/32645>.

Automatically sets the value of options("width") when the terminal emulator is resized. The functions of this package only work if R is compiled for Unix systems and it is running interactively in a terminal emulator.

This package provides functions for automated noncompartmental pharmacokinetic (NCA) analysis using concentration-time data. The package estimates pharmacokinetic parameters including area under the concentration-time curve (AUC), area under the first moment curve (AUMC), maximum concentration (Cmax), time to maximum concentration (Tmax), terminal elimination rate constant (Kel), elimination half-life, clearance, volume of distribution, and mean residence time (MRT). It supports automatic terminal phase selection, bootstrap confidence intervals, and publication-ready concentration-time profiles. Methods are based on Gibaldi and Perrier (1982, ISBN:9780824710422).

Implementation of SING algorithm to extract joint and individual non-Gaussian components from two datasets. SING uses an objective function that maximizes the skewness and kurtosis of latent components with a penalty to enhance the similarity between subject scores. Unlike other existing methods, SING does not use PCA for dimension reduction, but rather uses non-Gaussianity, which can improve feature extraction. Benjamin B.Risk, Irina Gaynanova (2021) <doi:10.1214/21-AOAS1466>.

Collection of utility functions supporting statistical modeling, regression analysis, and network analysis workflows used in data science research. Includes tools for model selection, matrix operations, graph analysis, and related statistical computations.

This package creates 3D animated, interactive visualizations that can be viewed in a web browser.

Sparse principal component analysis (SPCA) attempts to find sparse weight vectors (loadings), i.e., a weight vector with only a few active (nonzero) values. This approach provides better interpretability for the principal components in high-dimensional data settings. This is, because the principal components are formed as a linear combination of only a few of the original variables. This package provides efficient routines to compute SPCA. Specifically, a variable projection solver is used to compute the sparse solution. In addition, a fast randomized accelerated SPCA routine and a robust SPCA routine is provided. Robust SPCA allows to capture grossly corrupted entries in the data. The methods are discussed in detail by N. Benjamin Erichson et al. (2018) <arXiv:1804.00341>.

This package implements an extension of the Generalized Berk-Jones (GBJ) statistic for survival data, sGBJ. It computes the sGBJ statistic and its p-value for testing the association between a gene set and a time-to-event outcome with possible adjustment on additional covariates. Detailed method is available at Villain L, Ferte T, Thiebaut R and Hejblum BP (2021) <doi:10.1101/2021.09.07.459329>.

Encapsulates a number of spatially balanced sampling algorithms, namely, Balanced Acceptance Sampling (equal, unequal, seed point, panels), Halton frames (for discretizing a continuous resource), Halton Iterative Partitioning (equal probability) and Simple Random Sampling. Robertson, B. L., Brown, J. A., McDonald, T. and Jaksons, P. (2013) <doi:10.1111/biom.12059>. Robertson, B. L., McDonald, T., Price, C. J. and Brown, J. A. (2017) <doi:10.1016/j.spl.2017.05.004>. Robertson, B. L., McDonald, T., Price, C. J. and Brown, J. A. (2018) <doi:10.1007/s10651-018-0406-6>. Robertson, B. L., van Dam-Bates, P. and Gansell, O. (2021a) <doi:10.1007/s10651-020-00481-1>. Robertson, B. L., Davies, P., Gansell, O., van Dam-Bates, P., McDonald, T. (2025) <doi:10.1111/anzs.12435>.

Bindings for the SparseDiffEngine C library, the sparse Jacobian and Hessian differentiation backend used by CVXPY for its Disciplined Nonlinear Programming (DNLP) extension. Provides low-level routines for building nonlinear expression graphs and evaluating sparse derivatives, intended as a backend for higher-level modeling layers such as CVXR'. This is the R analog of the sparsediffpy Python package and wraps the same C library.

Terrestrial and marine predictors for species distribution modelling from multiple sources, including WorldClim <https://www.worldclim.org/>,, ENVIREM <https://envirem.github.io/>, Bio-ORACLE <https://bio-oracle.org/> and MARSPEC <http://www.marspec.org/>.

This package implements the Staggered Synthetic Control (SSC) method for estimating treatment effects in panel data with staggered adoption, as proposed by Cao, Lu, and Wu (2020) <doi:10.48550/arXiv.1912.06320>. Constructs synthetic control weights via constrained quadratic programming, estimates heterogeneous treatment effects and event-time average treatment effects on the treated (ATT), and provides placebo-in-time confidence intervals and p-values.

This package provides tools for sample survey planning, including sample size calculation, estimation of expected precision for the estimates of totals, and calculation of optimal sample size allocation.

This package implements the s-values proposed by Ed. Leamer. It provides a context-minimal approach for sensitivity analysis using extreme bounds to assess the sturdiness of regression coefficients.

Browser notifications in Shiny apps, using toastr': <https://github.com/CodeSeven/toastr#readme>.

This package provides a framework for simulating spatially explicit genomic data which leverages real cartographic information for programmatic and visual encoding of spatiotemporal population dynamics on real geographic landscapes. Population genetic models are then automatically executed by the SLiM software by Haller et al. (2019) <doi:10.1093/molbev/msy228> behind the scenes, using a custom built-in simulation SLiM script. Additionally, fully abstract spatial models not tied to a specific geographic location are supported, and users can also simulate data from standard, non-spatial, random-mating models. These can be simulated either with the SLiM built-in back-end script, or using an efficient coalescent population genetics simulator msprime by Baumdicker et al. (2022) <doi:10.1093/genetics/iyab229> with a custom-built Python script bundled with the R package. Simulated genomic data is saved in a tree-sequence format and can be loaded, manipulated, and summarised using tree-sequence functionality via an R interface to the Python module tskit by Kelleher et al. (2019) <doi:10.1038/s41588-019-0483-y>. Complete model configuration, simulation and analysis pipelines can be therefore constructed without a need to leave the R environment, eliminating friction between disparate tools for population genetic simulations and data analysis.

Computes smooth estimations for the Cumulative/Dynamic and Incident/Dynamic ROC curves, in presence of right censorship, based on the bivariate kernel density estimation of the joint distribution function of the Marker and Time-to-event variables.

Pass named and unnamed character vectors into specified positions in strings. This represents an attempt to replicate some of python's string formatting.

Fits spatial mixture models, including spatial Gaussian mixtures and mixtures of spatial factor analyzers, to complete or incomplete data. Spatial decay can be represented by monotone I-splines or a normalized sigmoid. Missing entries are handled using a built-in partial expectation-maximization procedure for matrix-variate data. The spatial covariance and spatial factor analyzer models are described in Lu and colleagues (2026a) "Spatial Covariance Constraints for Gaussian Mixture Models" <doi:10.48550/arXiv.2601.07979> and Lu and colleagues (2026b) "Mixtures of spatial factor analyzers for tensor-variate data" <doi:10.48550/arXiv.2607.07887>.

Implementation of popular mortality models using the rstan package, which provides the R interface to the Stan C++ library for Bayesian estimation. The package supports well-known models proposed in the actuarial and demographic literature including the Lee-Carter (1992) <doi:10.1080/01621459.1992.10475265> and the Cairns-Blake-Dowd (2006) <doi:10.1111/j.1539-6975.2006.00195.x> models. By a simple call, the user inputs deaths and exposures and the package outputs the MCMC simulations for each parameter, the log likelihoods and predictions. Moreover, the package includes tools for model selection and Bayesian model averaging by leave future-out validation.

This package implements SelectBoost'-style variable selection workflows for functional data analysis. The package provides FDA-native design and preprocessing objects for raw curves, spline-basis expansions, Functional principal component analysis scores, and scalar covariates; grouped stability-selection routines based on repeated subject-level subsampling; multiple selector backends including lasso, group lasso, and sparse-group lasso; FDA-aware grouping functions and calibration helpers for SelectBoost'; method-comparison utilities; a formula interface; simulation, benchmarking, and validation helpers with mapped ground truth; targeted sensitivity-study utilities and shipped benchmark summaries for mean F1 comparisons between FDA-aware and plain SelectBoost workflows; small example datasets; and an optional adapter to the native stability-selection interface from the FDboost package.

The methods discussed in this package are new non-parametric methods based on sequential normal scores SNS (Conover et al (2017) <doi:10.1080/07474946.2017.1360091>), designed for sequences of observations, usually time series data, which may occur singly or in batches, and may be univariate or multivariate. These methods are designed to detect changes in the process, which may occur as changes in location (mean or median), changes in scale (standard deviation, or variance), or other changes of interest in the distribution of the observations, over the time observed. They usually apply to large data sets, so computations need to be simple enough to be done in a reasonable time on a computer, and easily updated as each new observation (or batch of observations) becomes available. Some examples and more detail in SNS is presented in the work by Conover et al (2019) <arXiv:1901.04443>.

This package implements a segmentation algorithm for multiple change-point detection in high-dimensional GARCH processes. It simultaneously segments GARCH processes by identifying common change-points, each of which can be shared by a subset or all of the component time series as a change-point in their within-series and/or cross-sectional correlation structure.