Identifying cell types based on expression profiles is a pillar of single cell analysis. scROSHI identifies cell types based on expression profiles of single cell analysis by utilizing previously obtained cell type specific gene sets. It takes into account the hierarchical nature of cell type relationship and does not require training or annotated data. A detailed description of the method can be found at: Prummer, Bertolini, Bosshard, Barkmann, Yates, Boeva, The Tumor Profiler Consortium, Stekhoven, and Singer (2022) <doi:10.1101/2022.04.05.487176>.

Supporting materials for a course and book on data visualization. It contains utility functions for graphs and several sample data sets. See Healy (2019) <ISBN 978-0691181622>.

Offers a systematic way for conditional reporting of figures and tables for many (and bivariate combinations of) variables, typically from survey data. Contains interactive ggiraph'-based (<https://CRAN.R-project.org/package=ggiraph>) plotting functions and data frame-based summary tables (bivariate significance tests, frequencies/proportions, unique open ended responses, etc) with many arguments for customization, and extensions possible. Uses a global options() system for neatly reducing redundant code. Also contains tools for immediate saving of objects and returning a hashed link to the object, useful for creating download links to high resolution images upon rendering in Quarto'. Suitable for highly customized reports, primarily intended for survey research.

R-side code to implement an R editor and IDE in Komodo IDE with the SciViews-K extension.

Privacy protected raster maps can be created from spatial point data. Protection methods include smoothing of dichotomous variables by de Jonge and de Wolf (2016) <doi:10.1007/978-3-319-45381-1_9>, continuous variables by de Wolf and de Jonge (2018) <doi:10.1007/978-3-319-99771-1_23>, suppressing revealing values and a generalization of the quad tree method by Suñé, Rovira, Ibáñez and Farré (2017) <doi:10.2901/EUROSTAT.C2017.001>.

This package provides tools for researchers to explicitly show that their results comply to rules for statistical disclosure control imposed by research data centers. These tools help in checking descriptive statistics and models and in calculating extreme values that are not individual data. Also included is a simple function to create log files. The methods used here are described in the "Guidelines for the checking of output based on microdata research" by Bond, Brandt, and de Wolf (2015) <https://cros.ec.europa.eu/system/files/2024-02/Output-checking-guidelines.pdf>.

Extract the signed backbones of intrinsically dense weighted networks based on the significance filter and vigor filter as described in the following paper. Please cite it if you find this software useful in your work. Furkan Gursoy and Bertan Badur. "Extracting the signed backbone of intrinsically dense weighted networks." Journal of Complex Networks. <arXiv:2012.05216>.

This package provides a toolkit for stratified medicine, subgroup identification, and precision medicine. Current tools include (1) filtering models (reduce covariate space), (2) patient-level estimate models (counterfactual patient-level quantities, such as the conditional average treatment effect), (3) subgroup identification models (find subsets of patients with similar treatment effects), and (4) treatment effect estimation and inference (for the overall population and discovered subgroups). These tools can be customized and are directly used in PRISM (patient response identifiers for stratified medicine; Jemielita and Mehrotra 2019 <doi:10.48550/arXiv.1912.03337>).

This package provides a fast implementation with additional experimental features for testing, monitoring and dating structural changes in (linear) regression models. strucchangeRcpp features tests/methods from the generalized fluctuation test framework as well as from the F test (Chow test) framework. This includes methods to fit, plot and test fluctuation processes (e.g. cumulative/moving sum, recursive/moving estimates) and F statistics, respectively. These methods are described in Zeileis et al. (2002) <doi:10.18637/jss.v007.i02>. Finally, the breakpoints in regression models with structural changes can be estimated together with confidence intervals, and their magnitude as well as the model fit can be evaluated using a variety of statistical measures.

Simple SendGrid Email API client for creating and sending emails. For more information, visit the official SendGrid Email API documentation: <https://sendgrid.com/en-us/solutions/email-api>.

An htmlwidget of the human body that allows you to hide/show and assign colors to 79 different body parts. The human widget is an htmlwidget', so it works in Quarto documents, R Markdown documents, or any other HTML medium. It also functions as an input/output widget in a shiny app.

This package implements several functions for the analysis of semantic networks including different network estimation algorithms, partial node bootstrapping (Kenett, Anaki, & Faust, 2014 <doi:10.3389/fnhum.2014.00407>), random walk simulation (Kenett & Austerweil, 2016 <http://alab.psych.wisc.edu/papers/files/Kenett16CreativityRW.pdf>), and a function to compute global network measures. Significance tests and plotting features are also implemented.

Incorporate various statistics and layout customization options to enhance the efficiency and adaptability of the Kaplan-Meier plots.

This package provides functions for sample size estimation and simulation in clinical trials. Includes methods for selecting the best group using the Indifference-zone approach, as well as designs for non-inferiority, equivalence, and negative binomial models. For the sample size calculation for non-inferiority of vaccines, the approach is based on Fleming, Powers, and Huang (2021) <doi:10.1177/1740774520988244>. The Indifference-zone approach is based on Sobel and Huyett (1957) <doi:10.1002/j.1538-7305.1957.tb02411.x> and Bechhofer, Santner, and Goldsman (1995, ISBN:978-0-471-57427-9).

This package provides a general framework to perform statistical inference of each gene pair and global inference of whole-scale gene pairs in gene networks using the well known Gaussian graphical model (GGM) in a time-efficient manner. We focus on the high-dimensional settings where p (the number of genes) is allowed to be far larger than n (the number of subjects). Four main approaches are supported in this package: (1) the bivariate nodewise scaled Lasso (Ren et al (2015) <doi:10.1214/14-AOS1286>) (2) the de-sparsified nodewise scaled Lasso (Jankova and van de Geer (2017) <doi:10.1007/s11749-016-0503-5>) (3) the de-sparsified graphical Lasso (Jankova and van de Geer (2015) <doi:10.1214/15-EJS1031>) (4) the GGM estimation with false discovery rate control (FDR) using scaled Lasso or Lasso (Liu (2013) <doi:10.1214/13-AOS1169>). Windows users should install Rtools before the installation of this package.

SigClust is a statistical method for testing the significance of clustering results. SigClust can be applied to assess the statistical significance of splitting a data set into two clusters. For more than two clusters, SigClust can be used iteratively.

This package provides a series of checks to identify common issues in Study Data Tabulation Model (SDTM) datasets. These checks are intended to be generalizable, actionable, and meaningful for analysis.

Spectra viewer, organizer, data preparation and property blocks from within R or stand-alone. Binary (application) part is installed separately using spnInstallApp() from spectrino package.

Pull data from the STAT Search Analytics API <https://help.getstat.com/knowledgebase/api-services/>. It was developed by the Search Discovery team to help analyze keyword ranking data.

Making specification curve analysis easy, fast, and pretty. It improves upon existing offerings with additional features and tidyverse integration. Users can easily visualize and evaluate how their models behave under different specifications with a high degree of customization. For a description and applications of specification curve analysis see Simonsohn, Simmons, and Nelson (2020) <doi:10.1038/s41562-020-0912-z>.

This package provides tools for designing spatially explicit capture-recapture studies of animal populations. This is primarily a simulation manager for package secr'. Extensions in version 2.5.0 include costing and evaluation of detector spacing.

Performing cell type annotation based on cell markers from a unified database. The approach utilizes correlation-based approach combined with association analysis using Fisher-exact and phyper statistical tests (Upton, Graham JG. (1992) <DOI:10.2307/2982890>).

This package contains various functions to be used for simulation education, including simple Monte Carlo simulation functions, queueing simulation functions, variate generation functions capable of producing independent streams and antithetic variates, functions for illustrating random variate generation for various discrete and continuous distributions, and functions to compute time-persistent statistics. Also contains functions for visualizing: event-driven details of a single-server queue model; a Lehmer random number generator; variate generation via acceptance-rejection; and of generating a non-homogeneous Poisson process via thinning. Also contains two queueing data sets (one fabricated, one real-world) to facilitate input modeling. More details on the use of these functions can be found in Lawson and Leemis (2015) <doi:10.1109/WSC.2017.8248124>, in Kudlay, Lawson, and Leemis (2020) <doi:10.1109/WSC48552.2020.9384010>, and in Lawson and Leemis (2021) <doi:10.1109/WSC52266.2021.9715299>.

This package provides functions that compute the spatial covariance matrix for the matern and power classes of spatial models, for data that arise on rectangular units. This code can also be used for the change of support problem and for spatial data that arise on irregularly shaped regions like counties or zipcodes by laying a fine grid of rectangles and aggregating the integrals in a form of Riemann integration.