It provides miscellaneous sequence analysis functions for describing episodes in individual sequences, measuring association between domains in multidimensional sequence analysis (see Piccarreta (2017) <doi:10.1177/0049124115591013>), heat maps of sequence data, Globally Interdependent Multidimensional Sequence Analysis (see Robette et al (2015) <doi:10.1177/0081175015570976>), smoothing sequences for index plots (see Piccarreta (2012) <doi:10.1177/0049124112452394>), coding sequences for Qualitative Harmonic Analysis (see Deville (1982)), measuring stress from multidimensional scaling factors (see Piccarreta and Lior (2010) <doi:10.1111/j.1467-985X.2009.00606.x>), symmetrical (or canonical) Partial Least Squares (see Bry (1996)).

This package provides a statistical learning method to simultaneously predict a range of target phenotypes using codified and natural language processing (NLP)-derived Electronic Health Record (EHR) data. See Ahuja et al (2020) JAMIA <doi:10.1093/jamia/ocaa079> for details.

Herein, we provide a broad variety of functions which are useful for handling, manipulating, and visualizing satellite-based remote sensing data. These operations range from mere data import and layer handling (eg subsetting), over Raster* typical data wrangling (eg crop, extend), to more sophisticated (pre-)processing tasks typically applied to satellite imagery (eg atmospheric and topographic correction). This functionality is complemented by a full access to the satellite layers metadata at any stage and the documentation of performed actions in a separate log file. Currently available sensors include Landsat 4-5 (TM), 7 (ETM+), and 8 (OLI/TIRS Combined), and additional compatibility is ensured for the Landsat Global Land Survey data set.

By adding dependencies to the "Suggests" field of a package's DESCRIPTION file, and then declaring that they are needed within any dependent functionality, it is often possible to significantly reduce the number of "hard" dependencies required by a package. This package provides a minimal way to declare when a suggested package is needed.

Soft-margin support vector machines (SVMs) are a common class of classification models. The training of SVMs usually requires that the data be available all at once in a single batch, however the Stochastic majorization-minimization (SMM) algorithm framework allows for the training of SVMs on streamed data instead Nguyen, Jones & McLachlan(2018)<doi:10.1007/s42081-018-0001-y>. This package utilizes the SMM framework to provide functions for training SVMs with hinge loss, squared-hinge loss, and logistic loss.

Powerful graphical displays and statistical tools for structured problem solving and diagnosis. The functions of the sherlock package are especially useful for applying the process of elimination as a problem diagnosis technique. The sherlock package was designed to seamlessly work with the tidyverse set of packages and provides a collection of graphical displays built on top of the ggplot and plotly packages, such as different kinds of small multiple plots as well as helper functions such as adding reference lines, normalizing observations, reading in data or saving analysis results in an Excel file. References: David Hartshorne (2019, ISBN: 978-1-5272-5139-7). Stefan H. Steiner, R. Jock MacKay (2005, ISBN: 0873896467).

The Simulation-based Sampling Protocol (SSP) is an R package designed to estimate sampling effort in studies of ecological communities. It is based on the concept of pseudo-multivariate standard error (MultSE) (Anderson & Santana-Garcon, 2015, <doi:10.1111/ele.12385>) and the simulation of ecological data. The theoretical background is described in Guerra-Castro et al. (2020, <doi:10.1111/ecog.05284>).

This package performs structured OLS (sOLS) and structured SIR (sSIR).

Offers Bayesian semiparametric density estimation and tail-index estimation for heavy tailed data, by using a parametric, tail-respecting transformation of the data to the unit interval and then modeling the transformed data with a purely nonparametric logistic Gaussian process density prior. Based on Tokdar et al. (2022) <doi:10.1080/01621459.2022.2104727>.

Combining Predictive Analytics and Experimental Design to Optimize Results. To be utilized to select a test data calibrated training population in high dimensional prediction problems and assumes that the explanatory variables are observed for all of the individuals. Once a "good" training set is identified, the response variable can be obtained only for this set to build a model for predicting the response in the test set. The algorithms in the package can be tweaked to solve some other subset selection problems.

Computes scores of outlyingness for data sets consisting of nominal variables and includes various evaluation metrics for assessing performance of outlier identification algorithms producing scores of outlyingness. The scores of nominal outlyingness are computed based on the framework of Costa and Papatsouma (2025) <doi:10.48550/arXiv.2408.07463>.

Sparse principal component analysis (SPCA) attempts to find sparse weight vectors (loadings), i.e., a weight vector with only a few active (nonzero) values. This approach provides better interpretability for the principal components in high-dimensional data settings. This is, because the principal components are formed as a linear combination of only a few of the original variables. This package provides efficient routines to compute SPCA. Specifically, a variable projection solver is used to compute the sparse solution. In addition, a fast randomized accelerated SPCA routine and a robust SPCA routine is provided. Robust SPCA allows to capture grossly corrupted entries in the data. The methods are discussed in detail by N. Benjamin Erichson et al. (2018) <arXiv:1804.00341>.

Stochastic Newton Sampler (SNS) is a Metropolis-Hastings-based, Markov Chain Monte Carlo sampler for twice differentiable, log-concave probability density functions (PDFs) where the proposal density function is a multivariate Gaussian resulting from a second-order Taylor-series expansion of log-density around the current point. The mean of the Gaussian proposal is the full Newton-Raphson step from the current point. A Boolean flag allows for switching from SNS to Newton-Raphson optimization (by choosing the mean of proposal function as next point). This can be used during burn-in to get close to the mode of the PDF (which is unique due to concavity). For high-dimensional densities, mixing can be improved via state space partitioning strategy, in which SNS is applied to disjoint subsets of state space, wrapped in a Gibbs cycle. Numerical differentiation is available when analytical expressions for gradient and Hessian are not available. Facilities for validation and numerical differentiation of log-density are provided. Note: Formerly available versions of the MfUSampler can be obtained from the archive <https://cran.r-project.org/src/contrib/Archive/MfUSampler/>.

This package provides functions for modeling Soil Organic Matter decomposition in terrestrial ecosystems with linear and nonlinear systems of differential equations. The package implements models according to the compartmental system representation described in Sierra and others (2012) <doi:10.5194/gmd-5-1045-2012> and Sierra and others (2014) <doi:10.5194/gmd-7-1919-2014>.

Predicts the presence of signal peptides in eukaryotic protein using hidden semi-Markov models. The implemented algorithm can be accessed from both the command line and GUI.

This package implements a regularization method for cumulative link models using the Smooth-Effect-on-Response Penalty (SERP). This method allows flexible modeling of ordinal data by enabling a smooth transition from a general cumulative link model to a simplified version of the same model. As the tuning parameter increases from zero to infinity, the subject-specific effects for each variable converge to a single global effect. The approach addresses common issues in cumulative link models, such as parameter unidentifiability and numerical instability, by maximizing a penalized log-likelihood instead of the standard non-penalized version. Fitting is performed using a modified Newton's method. Additionally, the package includes various model performance metrics and descriptive tools. For details on the implemented penalty method, see Ugba (2021) <doi:10.21105/joss.03705> and Ugba et al. (2021) <doi:10.3390/stats4030037>.

Used for creating swimmers plots with functions to customize the bars, add points, add lines, add text, and add arrows.

An implementation of a single-index regression for optimizing individualized dose rules from an observational study. To model interaction effects between baseline covariates and a treatment variable defined on a continuum, we employ two-dimensional penalized spline regression on an index-treatment domain, where the index is defined as a linear combination of the covariates (a single-index). An unspecified main effect for the covariates is allowed, which can also be modeled through a parametric model. A unique contribution of this work is in the parsimonious single-index parametrization specifically defined for the interaction effect term. We refer to Park, Petkova, Tarpey, and Ogden (2020) <doi:10.1111/biom.13320> (for the case of a discrete treatment) and Park, Petkova, Tarpey, and Ogden (2021) "A single-index model with a surface-link for optimizing individualized dose rules" <arXiv:2006.00267v2> for detail of the method. The model can take a member of the exponential family as a response variable and can also take an ordinal categorical response. The main function of this package is simsl().

Unsupervised text tokenizer allowing to perform byte pair encoding and unigram modelling. Wraps the sentencepiece library <https://github.com/google/sentencepiece> which provides a language independent tokenizer to split text in words and smaller subword units. The techniques are explained in the paper "SentencePiece: A simple and language independent subword tokenizer and detokenizer for Neural Text Processing" by Taku Kudo and John Richardson (2018) <doi:10.18653/v1/D18-2012>. Provides as well straightforward access to pretrained byte pair encoding models and subword embeddings trained on Wikipedia using word2vec', as described in "BPEmb: Tokenization-free Pre-trained Subword Embeddings in 275 Languages" by Benjamin Heinzerling and Michael Strube (2018) <http://www.lrec-conf.org/proceedings/lrec2018/pdf/1049.pdf>.

This package provides functions connecting to the Salesforce Platform APIs (REST, SOAP, Bulk 1.0, Bulk 2.0, Metadata, Reports and Dashboards) <https://trailhead.salesforce.com/content/learn/modules/api_basics/api_basics_overview>. "API" is an acronym for "application programming interface". Most all calls from these APIs are supported as they use CSV, XML or JSON data that can be parsed into R data structures. For more details please see the Salesforce API documentation and this package's website <https://stevenmmortimer.github.io/salesforcer/> for more information, documentation, and examples.

High dimensional survival data analysis with Markov Chain Monte Carlo(MCMC). Currently supports frailty data analysis. Allows for Weibull and Exponential distribution. Includes function for interval censored data.

Efficient variational inference methods for fully Bayesian Gaussian Process Regression (GPR) models with hierarchical shrinkage priors, including the triple gamma prior for effective variable selection and covariance shrinkage in high-dimensional settings. The package leverages normalizing flows to approximate complex posterior distributions. For details on implementation, see Knaus (2025) <doi:10.48550/arXiv.2501.13173>.

Perform biomarker evaluation and comparison in terms of specificity at a controlled sensitivity level, or sensitivity at a controlled specificity level. Point estimation and exact bootstrap of Huang, Parakati, Patil, and Sanda (2023) <doi:10.5705/ss.202021.0020> for the one- and two-biomarker problems are implemented.

An implementation of the surrogate approach to residuals and diagnostics for ordinal and general regression models; for details, see Liu and Zhang (2017) <doi:10.1080/01621459.2017.1292915>. These residuals can be used to construct standard residual plots for model diagnostics (e.g., residual-vs-fitted value plots, residual-vs-covariate plots, Q-Q plots, etc.). The package also provides an autoplot function for producing standard diagnostic plots using ggplot2 graphics. The package currently supports cumulative link models from packages MASS', ordinal', rms', and VGAM'. Support for binary regression models using the standard glm function is also available.