Allows fitting of step-functions to univariate serial data where neither the number of jumps nor their positions is known by implementing the multiscale regression estimators SMUCE, simulataneous multiscale changepoint estimator, (K. Frick, A. Munk and H. Sieling, 2014) <doi:10.1111/rssb.12047> and HSMUCE, heterogeneous SMUCE, (F. Pein, H. Sieling and A. Munk, 2017) <doi:10.1111/rssb.12202>. In addition, confidence intervals for the change-point locations and bands for the unknown signal can be obtained.

On discrete data spectral analysis is performed by Fourier and Hilbert transforms as well as with model based analysis called Lomb-Scargle method. Fragmented and irregularly spaced data can be processed in almost all methods. Both, FFT as well as LOMB methods take multivariate data and return standardized PSD. For didactic reasons an analytical approach for deconvolution of noise spectra and sampling function is provided. A user friendly interface helps to interpret the results.

Simulate event history data from a framework where treatment decisions and disease progression are represented as counting process. The user can specify number of events and parameters of intensities thereby creating a flexible simulation framework.

This package provides a high-level, object-oriented interface for Secure File Transfer Protocol (SFTP) operations built upon the curl package. The package implements an R6 class to manage persistent connections and provides tidyverse'-style functions for common file system tasks. Key features include recursive directory creation with idempotency support, "smart" local path resolution that distinguishes between files and directories, and the ability to download remote resources directly into memory as raw vectors for seamless integration into data processing pipelines. It is designed to handle common SFTP edge cases gracefully, providing informative error messages and robust path sanitization to ensure compatibility across different server configurations.

Generates Skew Factor Models data and applies Sparse Online Principal Component (SOPC), Incremental Principal Component (IPC), Projected Principal Component (PPC), Perturbation Principal Component (PPC), Stochastic Approximation Principal Component (SAPC), Sparse Principal Component (SPC) and other PC methods to estimate model parameters. It includes capabilities for calculating mean squared error, relative error, and sparsity of the loading matrix.The philosophy of the package is described in Guo G. (2023) <doi:10.1007/s00180-022-01270-z>.

Flexible stochastic tree ensemble software. Robust implementations of Bayesian Additive Regression Trees (BART) (Chipman, George, McCulloch (2010) <doi:10.1214/09-AOAS285>) for supervised learning and Bayesian Causal Forests (BCF) (Hahn, Murray, Carvalho (2020) <doi:10.1214/19-BA1195>) for causal inference. Enables model serialization and parallel sampling and provides a low-level interface for custom stochastic forest samplers. Includes the grow-from-root algorithm for accelerated forest sampling (He and Hahn (2021) <doi:10.1080/01621459.2021.1942012>), a log-linear leaf model for forest-based heteroskedasticity (Murray (2020) <doi:10.1080/01621459.2020.1813587>), and the cloglog BART model of Alam and Linero (2025) <doi:10.48550/arXiv.2502.00606> for ordinal outcomes.

Launch a shiny application for tidymodels results. For classification or regression models, the app can be used to determine if there is lack of fit or poorly predicted points.

Algorithms to create prognostic biomarkers using biological genesets or networks.

Maximum likelihood tools to fit and compare models of species abundance distributions and of species rank-abundance distributions.

This package implements the SparseStep model for solving regression problems with a sparsity constraint on the parameters. The SparseStep regression model was proposed in Van den Burg, Groenen, and Alfons (2017) <arXiv:1701.06967>. In the model, a regularization term is added to the regression problem which approximates the counting norm of the parameters. By iteratively improving the approximation a sparse solution to the regression problem can be obtained. In this package both the standard SparseStep algorithm is implemented as well as a path algorithm which uses golden section search to determine solutions with different values for the regularization parameter.

The sinaplot is a data visualization chart suitable for plotting any single variable in a multiclass data set. It is an enhanced jitter strip chart, where the width of the jitter is controlled by the density distribution of the data within each class.

Single-cell Interpretable Tensor Decomposition (scITD) employs the Tucker tensor decomposition to extract multicell-type gene expression patterns that vary across donors/individuals. This tool is geared for use with single-cell RNA-sequencing datasets consisting of many source donors. The method has a wide range of potential applications, including the study of inter-individual variation at the population-level, patient sub-grouping/stratification, and the analysis of sample-level batch effects. Each "multicellular process" that is extracted consists of (A) a multi cell type gene loadings matrix and (B) a corresponding donor scores vector indicating the level at which the corresponding loadings matrix is expressed in each donor. Additional methods are implemented to aid in selecting an appropriate number of factors and to evaluate stability of the decomposition. Additional tools are provided for downstream analysis, including integration of gene set enrichment analysis and ligand-receptor analysis. Tucker, L.R. (1966) <doi:10.1007/BF02289464>. Unkel, S., Hannachi, A., Trendafilov, N. T., & Jolliffe, I. T. (2011) <doi:10.1007/s13253-011-0055-9>. Zhou, G., & Cichocki, A. (2012) <doi:10.2478/v10175-012-0051-4>.

Stores and eases the manipulation of spectra and associated data, with dedicated classes for spatial and soil-related data.

Penalized and non-penalized maximum likelihood estimation of smooth transition vector autoregressive models with various types of transition weight functions, conditional distributions, and identification methods. Constrained estimation with various types of constraints is available. Residual based model diagnostics, forecasting, simulations, counterfactual analysis, and computation of impulse response functions, generalized impulse response functions, generalized forecast error variance decompositions, as well as historical decompositions. See Heather Anderson, Farshid Vahid (1998) <doi:10.1016/S0304-4076(97)00076-6>, Helmut Lütkepohl, Aleksei Netšunajev (2017) <doi:10.1016/j.jedc.2017.09.001>, Markku Lanne, Savi Virolainen (2025) <doi:10.1016/j.jedc.2025.105162>, Savi Virolainen (in press) <doi:10.1080/07474938.2026.2673986>.

Import, create and assemble data needed to fit spatial-statistical stream-network models using the SSN2 package for R'. Streams, observations, and prediction locations are represented as simple features and specific tools provided to define topological relationships between features; calculate the hydrologic distances (with flow-direction preserved) and the spatial additive function used to weight converging stream segments; and export the topological, spatial, and attribute information to an `SSN` (spatial stream network) object, which can be efficiently stored, accessed and analysed in R'. A detailed description of methods used to calculate and format the spatial data can be found in Peterson, E.E. and Ver Hoef, J.M., (2014) <doi:10.18637/jss.v056.i02>.

The Structural Topic and Sentiment-Discourse (STS) model allows researchers to estimate topic models with document-level metadata that determines both topic prevalence and sentiment-discourse. The sentiment-discourse is modeled as a document-level latent variable for each topic that modulates the word frequency within a topic. These latent topic sentiment-discourse variables are controlled by the document-level metadata. The STS model can be useful for regression analysis with text data in addition to topic modelingâ s traditional use of descriptive analysis. The method was developed in Chen and Mankad (2024) <doi:10.1287/mnsc.2022.00261>.

This package provides an R interface to SCIP (Solving Constraint Integer Programs), a framework for mixed-integer programming (MIP), mixed-integer nonlinear programming (MINLP), and constraint integer programming (2025, <doi:10.48550/arXiv.2511.18580>). Supports linear, quadratic, SOS, indicator, and knapsack constraints with continuous, binary, and integer variables. Includes a one-shot solver interface and a model-building API for incremental problem construction.

Algorithms for fitting scaled sparse linear regression and estimating precision matrices.

Screen for and analyze non-linear sparse direct effects in the presence of unobserved confounding using the spectral deconfounding techniques (Ä evid, Bühlmann, and Meinshausen (2020)<jmlr.org/papers/v21/19-545.html>, Guo, Ä evid, and Bühlmann (2022) <doi:10.1214/21-AOS2152>). These methods have been shown to be a good estimate for the true direct effect if we observe many covariates, e.g., high-dimensional settings, and we have fairly dense confounding. Even if the assumptions are violated, it seems like there is not much to lose, and the deconfounded models will, in general, estimate a function closer to the true one than classical least squares optimization. SDModels provides functions SDAM() for Spectrally Deconfounded Additive Models (Scheidegger, Guo, and Bühlmann (2025) <doi:10.1145/3711116>) and SDForest() for Spectrally Deconfounded Random Forests (Ulmer, Scheidegger, and Bühlmann (2025) <doi:10.1080/10618600.2025.2569602>).

This package implements the ST-DBSCAN (spatio-temporal density-based spatial clustering of applications with noise) clustering algorithm for detecting spatially and temporally dense regions in point data, with a fast C++ backend via Rcpp'. Birant and Kut (2007) <doi:10.1016/j.datak.2006.01.013>.

This package implements a physics-informed one-dimensional convolutional neural network (CNN1D-PINN) for estimating the complete soil water retention curve (SWRC) as a continuous function of matric potential, from soil texture, organic carbon, bulk density, and depth. The network architecture ensures strict monotonic decrease of volumetric water content with increasing suction by construction, through cumulative integration of non-negative slope outputs (monotone integral architecture). Four physics-based residual constraints adapted from Norouzi et al. (2025) <doi:10.1029/2024WR038149> are embedded in the loss function: (S1) linearity at the dry end (pF in [5, 7.6]); (S2) non-negativity at pF = 6.2; (S3) non-positivity at pF = 7.6; and (S4) a near-zero derivative in the saturated plateau region (pF in [-2, -0.3]). Includes tools for data preparation, model training, dense prediction, performance metrics, texture classification, and publication-quality visualisation.

Computes the sBIC for various singular model collections including: binomial mixtures, factor analysis models, Gaussian mixtures, latent forests, latent class analyses, and reduced rank regressions.

Identifying spatially variable genes is critical in linking molecular cell functions with tissue phenotypes. This package utilizes a granularity-based dimension-agnostic tool, single-cell big-small patch (scBSP), implementing sparse matrix operation and KD tree methods for distance calculation, for the identification of spatially variable genes on large-scale data. The detailed description of this method is available at Wang, J. and Li, J. et al. 2023 (Wang, J. and Li, J. (2023), <doi:10.1038/s41467-023-43256-5>).

Symbolic data analysis methods: importing/exporting data from ASSO XML Files, distance calculation for symbolic data (Ichino-Yaguchi, de Carvalho measure), zoom star plot, 3d interval plot, multidimensional scaling for symbolic interval data, dynamic clustering based on distance matrix, HINoV method for symbolic data, Ichino's feature selection method, principal component analysis for symbolic interval data, decision trees for symbolic data based on optimal split with bagging, boosting and random forest approach (+visualization), kernel discriminant analysis for symbolic data, Kohonen's self-organizing maps for symbolic data, replication and profiling, artificial symbolic data generation. (Milligan, G.W., Cooper, M.C. (1985) <doi:10.1007/BF02294245>, Breiman, L. (1996), <doi:10.1007/BF00058655>, Hubert, L., Arabie, P. (1985), <doi:10.1007%2FBF01908075>, Ichino, M., & Yaguchi, H. (1994), <doi:10.1109/21.286391>, Rand, W.M. (1971) <doi:10.1080/01621459.1971.10482356>, Breckenridge, J.N. (2000) <doi:10.1207/S15327906MBR3502_5>, Groenen, P.J.F, Winsberg, S., Rodriguez, O., Diday, E. (2006) <doi:10.1016/j.csda.2006.04.003>, Dudek, A. (2007), <doi:10.1007/978-3-540-70981-7_4>).