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This package provides a toolbox for defining React component wrappers which can be used seamlessly in Shiny apps.
This package implements the SE-test for equivalence according to Hoffelder et al. (2015) <DOI:10.1080/10543406.2014.920344>. The SE-test for equivalence is a multivariate two-sample equivalence test. Distance measure of the test is the sum of standardized differences between the expected values or in other words: the sum of effect sizes (SE) of all components of the two multivariate samples. The test is an asymptotically valid test for normally distributed data (see Hoffelder et al.,2015). The function SE.EQ() implements the SE-test for equivalence according to Hoffelder et al. (2015). The function SE.EQ.dissolution.profiles() implements a variant of the SE-test for equivalence for similarity analyses of dissolution profiles as mentioned in Suarez-Sharp et al.(2020) <DOI:10.1208/s12248-020-00458-9>). The equivalence margin used in SE.EQ.dissolution.profiles() is analogically defined as for the T2EQ approach according to Hoffelder (2019) <DOI:10.1002/bimj.201700257>) by means of a systematic shift in location of 10 [\% of label claim] of both dissolution profile populations. SE.EQ.dissolution.profiles() checks whether the weighted mean of the differences of the expected values of both dissolution profile populations is statistically significantly smaller than 10 [\% of label claim]. The weights are built up by the inverse variances.
Fetch data on targeted public investments from Plataforma +Brasil (SICONV) <http://plataformamaisbrasil.gov.br/>, the responsible system for requests, execution, and monitoring of federal discretionary transfers in Brazil.
Calculates (unconditional) post-selection confidence intervals and p-values for the coefficients of (generalized) linear models.
This package implements the synthetic control group method for comparative case studies as described in Abadie and Gardeazabal (2003) and Abadie, Diamond, and Hainmueller (2010, 2011, 2014). The synthetic control method allows for effect estimation in settings where a single unit (a state, country, firm, etc.) is exposed to an event or intervention. It provides a data-driven procedure to construct synthetic control units based on a weighted combination of comparison units that approximates the characteristics of the unit that is exposed to the intervention. A combination of comparison units often provides a better comparison for the unit exposed to the intervention than any comparison unit alone.
This package provides a network module-based generalized linear model for differential expression analysis with the count-based sequence data from RNA-Seq.
Selective sweep is a biological phenomenon in which genetic variation between neighboring beneficial mutant alleles is swept away due to the effect of genetic hitchhiking. Detection of selective sweep is not well acquainted as well as it is a laborious job. This package is a user friendly approach for detecting selective sweep in genomic regions. It uses a Random Forest based machine learning approach to predict selective sweep from VCF files as an input. Input of this function, train data and new data, can be computed using the project <https://github.com/AbhikSarkar1999/SweepDiscovery> in GitHub'. This package has been developed by using the concept of Pavlidis and Alachiotis (2017) <doi:10.1186/s40709-017-0064-0>.
The StockDistFit package provides functions for fitting probability distributions to stock price data. The package uses maximum likelihood estimation to find the best-fitting distribution for a given stock. It also offers a function to fit several distributions to one or more assets and compare the distribution with the Akaike Information Criterion (AIC) and then pick the best distribution. References are as follows: Siew et al. (2008) <https://www.jstage.jst.go.jp/article/jappstat/37/1/37_1_1/_pdf/-char/ja> and Benth et al. (2008) <https://books.google.co.ke/books?hl=en&lr=&id=MHNpDQAAQBAJ&oi=fnd&pg=PR7&dq=Stochastic+modeling+of+commodity+prices+using+the+Variance+Gamma+(VG)+model.+&ots=YNIL2QmEYg&sig=XZtGU0lp4oqXHVyPZ-O8x5i7N3w&redir_esc=y#v=onepage&q&f=false>.
This package provides a-priori, post-hoc, and compromise power-analyses for structural equation models (SEM).
We propose a procedure for sample size calculation while controlling false discovery rate for RNA-seq experimental design. Our procedure depends on the Voom method proposed for RNA-seq data analysis by Law et al. (2014) <DOI:10.1186/gb-2014-15-2-r29> and the sample size calculation method proposed for microarray experiments by Liu and Hwang (2007) <DOI:10.1093/bioinformatics/btl664>. We develop a set of functions that calculates appropriate sample sizes for two-sample t-test for RNA-seq experiments with fixed or varied set of parameters. The outputs also contain a plot of power versus sample size, a table of power at different sample sizes, and a table of critical test values at different sample sizes. To install this package, please use source("http://bioconductor.org/biocLite.R"); biocLite("ssizeRNA")'. For R version 3.5 or greater, please use if(!requireNamespace("BiocManager", quietly = TRUE))install.packages("BiocManager"); BiocManager::install("ssizeRNA")'.
This package provides a unifying framework for managing and deploying shiny applications that consist of modules, where an "app" is a tab-based workflow that guides a user step-by-step through an analysis. The shinymgr app builder "stitches" shiny modules together so that outputs from one module serve as inputs to the next, creating an analysis pipeline that is easy to implement and maintain. Users of shinymgr apps can save analyses as an RDS file that fully reproduces the analytic steps and can be ingested into an R Markdown report for rapid reporting. In short, developers use the shinymgr framework to write modules and seamlessly combine them into shiny apps, and users of these apps can execute reproducible analyses that can be incorporated into reports for rapid dissemination.
Fit, summarize, and predict for a variety of spatial statistical models applied to point-referenced and areal (lattice) data. Parameters are estimated using various methods. Additional modeling features include anisotropy, non-spatial random effects, partition factors, big data approaches, and more. Model-fit statistics are used to summarize, visualize, and compare models. Predictions at unobserved locations are readily obtainable. For additional details, see Dumelle et al. (2023) <doi:10.1371/journal.pone.0282524>.
This package contains various functions to be used for simulation education, including simple Monte Carlo simulation functions, queueing simulation functions, variate generation functions capable of producing independent streams and antithetic variates, functions for illustrating random variate generation for various discrete and continuous distributions, and functions to compute time-persistent statistics. Also contains functions for visualizing: event-driven details of a single-server queue model; a Lehmer random number generator; variate generation via acceptance-rejection; and of generating a non-homogeneous Poisson process via thinning. Also contains two queueing data sets (one fabricated, one real-world) to facilitate input modeling. More details on the use of these functions can be found in Lawson and Leemis (2015) <doi:10.1109/WSC.2017.8248124>, in Kudlay, Lawson, and Leemis (2020) <doi:10.1109/WSC48552.2020.9384010>, and in Lawson and Leemis (2021) <doi:10.1109/WSC52266.2021.9715299>.
Compute the frequency distribution of a search term in a series of texts. For example, Arthur Conan Doyle wrote a total of 60 Sherlock Holmes stories, comprised of 54 short stories and 4 longer novels. I wanted to test my own subjective impression that, in many of the stories, Sherlock Holmes popularity was used as bait to induce the reader to read a story that is essentially not primarily a Sherlock Holmes story. I used the term "Holmes" as a search pattern, since Watson would frequently address him by name, or use his name to describe something that he was doing. My hypothesis is that the frequency distribution of the search pattern "Holmes" is a good proxy for the degree to which a story is or is not truly a Sherlock Holmes story. The results are presented in a manuscript that is available as a vignette and online at <https://barryzee.github.io/Concordance/index.html>.
Encrypt text using a simple shifting substitution cipher with setcode(), providing two numeric keys used to define the encryption algorithm. The resulting text can be decoded using decode() function and the two numeric keys specified during encryption.
This package provides estimates for the bivariate and trivariate distribution functions and bivariate and trivariate survival functions for censored gap times. Two approaches, using existing methodologies, are considered: (i) the Lin's estimator, which is based on the extension the Kaplan-Meier estimator of the distribution function for the first event time and the Inverse Probability of Censoring Weights for the second time (Lin DY, Sun W, Ying Z (1999) <doi:10.1093/biomet/86.1.59> and (ii) another estimator based on Kaplan-Meier weights (Una-Alvarez J, Meira-Machado L (2008) <https://w3.math.uminho.pt/~lmachado/Biometria_conference.pdf>). The proposed methods are the landmark estimators based on subsampling approach, and the estimator based on weighted cumulative hazard estimator. The package also provides nonparametric estimator conditional to a given continuous covariate. All these methods have been submitted to be published.
Computes the sBIC for various singular model collections including: binomial mixtures, factor analysis models, Gaussian mixtures, latent forests, latent class analyses, and reduced rank regressions.
Datasets detailing the results, castaways, and events of each season of Survivor for the US, Australia, South Africa, New Zealand, and the UK. This includes details on the cast, voting history, immunity and reward challenges, jury votes, boot order, advantage details, and episode ratings. Use this for analysis of trends and statistics of the game.
Identifying cell types based on expression profiles is a pillar of single cell analysis. scROSHI identifies cell types based on expression profiles of single cell analysis by utilizing previously obtained cell type specific gene sets. It takes into account the hierarchical nature of cell type relationship and does not require training or annotated data. A detailed description of the method can be found at: Prummer, Bertolini, Bosshard, Barkmann, Yates, Boeva, The Tumor Profiler Consortium, Stekhoven, and Singer (2022) <doi:10.1101/2022.04.05.487176>.
Get the most appropriate autoregressive integrated moving average, generalized auto-regressive conditional heteroscedasticity and Markov switching GARCH model. For method details see Haas M, Mittnik S, Paolella MS (2004). <doi:10.1093/jjfinec/nbh020>, Bollerslev T (1986). <doi:10.1016/0304-4076(86)90063-1>.
It is a toolbox for Sequential Probability Ratio Tests (SPRT), Wald (1945) <doi:10.2134/agronj1947.00021962003900070011x>. SPRTs are applied to the data during the sampling process, ideally after each observation. At any stage, the test will return a decision to either continue sampling or terminate and accept one of the specified hypotheses. The seq_ttest() function performs one-sample, two-sample, and paired t-tests for testing one- and two-sided hypotheses (Schnuerch & Erdfelder (2019) <doi:10.1037/met0000234>). The seq_anova() function allows to perform a sequential one-way fixed effects ANOVA (Steinhilber et al. (2023) <doi:10.31234/osf.io/m64ne>). Learn more about the package by using vignettes "browseVignettes(package = "sprtt")" or go to the website <https://meikesteinhilber.github.io/sprtt/>.
Spatial downscaling of climate data (Global Circulation Models/Regional Climate Models) using quantile-quantile bias correction technique.
Estimate the receiver operating characteristic (ROC) curve, area under the curve (AUC) and optimal cut-off points for individual classification taking into account complex sampling designs when working with complex survey data. Methods implemented in this package are described in: A. Iparragirre, I. Barrio, I. Arostegui (2024) <doi:10.1002/sta4.635>; A. Iparragirre, I. Barrio, J. Aramendi, I. Arostegui (2022) <doi:10.2436/20.8080.02.121>; A. Iparragirre, I. Barrio (2024) <doi:10.1007/978-3-031-65723-8_7>.
The Robots Exclusion Protocol <https://www.robotstxt.org/orig.html> documents a set of standards for allowing or excluding robot/spider crawling of different areas of site content. Tools are provided which wrap The rep-cpp <https://github.com/seomoz/rep-cpp> C++ library for processing these robots.txt files.