The number of studies involving correlated traits and the availability of tools to handle this type of data has increased considerably in the last decade. With such a demand, we need tools for testing hypotheses related to single and multi-trait (correlated) phenotypes based on many genetic settings. Thus, we implemented various options for simulation of pleiotropy and Linkage Disequilibrium under additive, dominance and epistatic models. The simulation currently takes a marker data set as an input and then uses it for simulating multiple traits as described in Fernandes and Lipka (2020) <doi:10.1186/s12859-020-03804-y>.

The developed function is designed for the generation of spatial grids based on user-specified longitude and latitude coordinates. The function first validates the input longitude and latitude values, ensuring they fall within the appropriate geographic ranges. It then creates a polygon from the coordinates and determines the appropriate Universal Transverse Mercator zone based on the provided hemisphere and longitude values. Subsequently, transforming the input Shapefile to the Universal Transverse Mercator projection when necessary. Finally, a spatial grid is generated with the specified interval and saved as a Shapefile. For method details see, Brus,D.J.(2022).<DOI:10.1201/9781003258940>. The function takes into account crucial parameters such as the hemisphere (north or south), desired grid interval, and the output Shapefile path. The developed function is an efficient tool, simplifying the process of empty spatial grid generation for applications such as, geo-statistical analysis, digital soil mapping product generation, etc. Whether for environmental studies, urban planning, or any other geo-spatial analysis, this package caters to the diverse needs of users working with spatial data, enhancing the accessibility and ease of spatial data processing and visualization.

Artificial selection through selective breeding is an efficient way to induce changes in traits of interest in experimental populations. This package (sra) provides a set of tools to analyse artificial-selection response datasets. The data typically feature for several generations the average value of a trait in a population, the variance of the trait, the population size and the average value of the parents that were chosen to breed. Sra implements two families of models aiming at describing the dynamics of the genetic architecture of the trait during the selection response. The first family relies on purely descriptive (phenomenological) models, based on an autoregressive framework. The second family provides different mechanistic models, accounting e.g. for inbreeding, mutations, genetic and environmental canalization, or epistasis. The parameters underlying the dynamics of the time series are estimated by maximum likelihood. The sra package thus provides (i) a wrapper for the R functions mle() and optim() aiming at fitting in a convenient way a predetermined set of models, and (ii) some functions to plot and analyze the output of the models.

Time series area-level models for small area estimation. The package supplements the functionality of the sae package. Specifically, it includes EBLUP fitting of the Rao-Yu model in the original form without a spatial component. The package also offers a modified ("dynamic") version of the Rao-Yu model, replacing the assumption of stationarity. Both univariate and multivariate applications are supported. Of particular note is the allowance for covariance of the area-level sample estimates over time, as encountered in rotating panel designs such as the U.S. National Crime Victimization Survey or present in a time-series of 5-year estimates from the American Community Survey. Key references to the methods include J.N.K. Rao and I. Molina (2015, ISBN:9781118735787), J.N.K. Rao and M. Yu (1994) <doi:10.2307/3315407>, and R.E. Fay and R.A. Herriot (1979) <doi:10.1080/01621459.1979.10482505>.

This package provides a framework to generating random variates from arbitrary multivariate copulae, while concentrating on (bivariate) extreme value copulae. Particularly useful if the multivariate copulae are not available in closed form. Detailed discussion of the methodologies used can be found in Tajvidi and Turlach (2018) <doi:10.1111/anzs.12209>.

Support for reading and writing files in StatDataML---an XML-based data exchange format.

This package provides a consistent, semi-supervised, non-parametric survival curve estimator optimized for efficient use of Electronic Health Record (EHR) data with a limited number of current status labels. See van der Laan and Robins (1997) <doi:10.2307/2670119>.

This package provides the core framework for a discrete event system to implement a complete data-to-decisions, reproducible workflow. The core components facilitate the development of modular pieces, and enable the user to include additional functionality by running user-built modules. Includes conditional scheduling, restart after interruption, packaging of reusable modules, tools for developing arbitrary automated workflows, automated interweaving of modules of different temporal resolution, and tools for visualizing and understanding the within-project dependencies. The suggested package NLMR can be installed from the repository (<https://PredictiveEcology.r-universe.dev>).

This package provides a collection of highly configurable, touch-enabled knob input controls for shiny'. These components can be styled to fit in perfectly in any app, and allow users to set precise values through many input modalities. Users can touch-and-drag, click-and-drag, scroll their mouse wheel, double click, or use keyboard input.

Offers a comprehensive solution for managing empty states in Shiny applications. It provides tools to create both default and customizable components for scenarios where data is absent or doesn't match user-defined filters. The package prioritizes user experience, ensuring clarity and consistency even when data is not available to display.

Landsat satellites collect important data about global forest conditions. Documentation about Landsat's role in forest disturbance estimation is available at the site <https://landsat.gsfc.nasa.gov/>. By constrained quadratic B-splines, this package delivers an optimal shape-restricted trajectory to a time series of Landsat imagery for the purpose of modeling annual forest disturbance dynamics to behave in an ecologically sensible manner assuming one of seven possible "shapes", namely, flat, decreasing, one-jump (decreasing, jump up, decreasing), inverted vee (increasing then decreasing), vee (decreasing then increasing), linear increasing, and double-jump (decreasing, jump up, decreasing, jump up, decreasing). The main routine selects the best shape according to the minimum Bayes information criterion (BIC) or the cone information criterion (CIC), which is defined as the log of the estimated predictive squared error. The package also provides parameters summarizing the temporal pattern including year(s) of inflection, magnitude of change, pre- and post-inflection rates of growth or recovery. In addition, it contains routines for converting a flat map of disturbance agents to time-series disturbance maps and a graphical routine displaying the fitted trajectory of Landsat imagery.

This package provides data about the Star Wars movie franchise in a set of relational tables or as a complete DuckDB database. All data was collected from the open source Star Wars API.

Aggregates large single-cell data into metacell dataset by merging together gene expression of very similar cells. SuperCell uses velocyto.R <doi:10.1038/s41586-018-0414-6> <https://github.com/velocyto-team/velocyto.R> for RNA velocity and WeightedCluster <doi:10.12682/lives.2296-1658.2013.24> <https://mephisto.unige.ch/weightedcluster/> for weighted clustering on metacells. We also recommend installing scater Bioconductor package <doi:10.18129/B9.bioc.scater> <https://bioconductor.org/packages/release/bioc/html/scater.html>.

This package provides methods to fit robust alternatives to commonly used models used in Small Area Estimation. The methods here used are based on best linear unbiased predictions and linear mixed models. At this time available models include area level models incorporating spatial and temporal correlation in the random effects.

This package contains space filling based tools for machine learning and data mining. Some functions offer several computational techniques and deal with the out of memory for large big data by using the ff package.

Provision of the S4 SpatialGraph class built on top of objects provided by igraph and sp packages, and associated utilities. See the documentation of the SpatialGraph-class within this package for further description. An example of how from a few points one can arrive to a SpatialGraph is provided in the function sl2sg().

This package performs predictions of totals and weighted sums, or finite population block kriging, on spatial data using the methods in Ver Hoef (2008) <doi:10.1007/s10651-007-0035-y>. The primary outputs are an estimate of the total, mean, or weighted sum in the region, an estimated prediction variance, and a plot of the predicted and observed values. This is useful primarily to users with ecological data that are counts or densities measured on some sites in a finite area of interest. Spatial prediction for the total count or average density in the entire region can then be done using the functions in this package.

This package provides a set of function that implements for seasonal multivariate time series analysis based on Seasonal Generalized Space Time Autoregressive with Seemingly Unrelated Regression (S-GSTAR-SUR) Model by Setiawan(2016)<https://www.researchgate.net/publication/316517889_S-GSTAR-SUR_model_for_seasonal_spatio_temporal_data_forecasting>.

Simulation tools to evaluate the long-term effects of salmon management strategies, including a combination of habitat, harvest, and habitat actions. The stochastic age-structured operating model accommodates complex life histories, including freshwater survival across early life stages, juvenile survival and fishery exploitation in the marine life stage, partial maturity by age class, and fitness impacts of hatchery programs on natural spawning populations. salmonMSE also provides an age-structured conditioning model to develop operating models fitted to data.

Facilitate phonetic transliteration between different languages. With support for both Hindi and English, this package provides a way to convert text between Hindi and English dataset. Whether you're working with multilingual data or need to convert dataset for analysis or presentation purposes, it offers a simple and efficient solution and harness the power of phonetic transliteration in your projects with this versatile package.

To automated functional annotation of genetic variants and linked proxies. Linked SNPs in moderate to high linkage disequilibrium (e.g. r2>0.50) with the corresponding index SNPs will be selected for further analysis.

Computing the one-sided/two-sided integrated/maximally selected EL statistics for simultaneous testing, the one-sided/two-sided EL tests for pointwise testing, and an initial test that precedes one-sided testing to exclude the possibility of crossings or alternative orderings among the survival functions.

Routines for creating, manipulating, and performing Bayesian inference about Gaussian processes in one and two dimensions using the Fourier basis approximation: simulation and plotting of processes, calculation of coefficient variances, calculation of process density, coefficient proposals (for use in MCMC). It uses R environments to store GP objects as references/pointers.

Local Correlation Integral (LOCI) method for outlier identification is implemented here. The LOCI method developed here is invented in Breunig, et al. (2000), see <doi:10.1145/342009.335388>.