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This package implements methods for variable selection in linear regression based on the "Sum of Single Effects" (SuSiE) model, as described in Wang et al (2020) <DOI:10.1101/501114> and Zou et al (2021) <DOI:10.1101/2021.11.03.467167>. These methods provide simple summaries, called "Credible Sets", for accurately quantifying uncertainty in which variables should be selected. The methods are motivated by genetic fine-mapping applications, and are particularly well-suited to settings where variables are highly correlated and detectable effects are sparse. The fitting algorithm, a Bayesian analogue of stepwise selection methods called "Iterative Bayesian Stepwise Selection" (IBSS), is simple and fast, allowing the SuSiE model be fit to large data sets (thousands of samples and hundreds of thousands of variables).
Finds causal connections in precision data, finds lags and embeddings in time series, guides training of neural networks and other smooth models, evaluates their performance, gives a mathematically grounded answer to the over-training problem. Smooth regression is based on the Gamma test, which measures smoothness in a multivariate relationship. Causal relations are smooth, noise is not. sr includes the Gamma test and search techniques that use it. References: Evans & Jones (2002) <doi:10.1098/rspa.2002.1010>, AJ Jones (2004) <doi:10.1007/s10287-003-0006-1>.
The computation of a seasonal index is a fundamental step in time-series forecasting when the data exhibits seasonality. Specifically, a seasonal index quantifies â for each season (e.g. month, quarter, week) â the relative magnitude of the seasonal effect compared to the overall average level of the series. This package has been developed to compute seasonal index for time series data and it also seasonalise and desesaonalise the time series data.
This is an implementation of the algorithm described in Section 3 of Hosszejni and Frühwirth-Schnatter (2026) <doi:10.1016/j.jmva.2025.105536>. The algorithm is used to verify that the counting rule CR(r,1) holds for the sparsity pattern of the transpose of a factor loading matrix. As detailed in Section 2 of the same paper, if CR(r,1) holds, then the idiosyncratic variances are generically identified. If CR(r,1) does not hold, then we do not know whether the idiosyncratic variances are identified or not.
This package provides an R interface to SymEngine <https://github.com/symengine/>, a standalone C++ library for fast symbolic manipulation. The package has functionalities for symbolic computation like calculating exact mathematical expressions, solving systems of linear equations and code generation.
Pathway Analysis is statistically linking observations on the molecular level to biological processes or pathways on the systems(i.e., organism, organ, tissue, cell) level. Traditionally, pathway analysis methods regard pathways as collections of single genes and treat all genes in a pathway as equally informative. However, this can lead to identifying spurious pathways as statistically significant since components are often shared amongst pathways. SIGORA seeks to avoid this pitfall by focusing on genes or gene pairs that are (as a combination) specific to a single pathway. In relying on such pathway gene-pair signatures (Pathway-GPS), SIGORA inherently uses the status of other genes in the experimental context to identify the most relevant pathways. The current version allows for pathway analysis of human and mouse datasets. In addition, it contains pre-computed Pathway-GPS data for pathways in the KEGG and Reactome pathway repositories and mechanisms for extracting GPS for user-supplied repositories.
This package provides tools to simulate and analyse datasets of social interactions between individuals using hierarchical Bayesian models implemented in Stan. Model fitting is performed via the rstan package. Users can generate realistic interaction data where individual phenotypes influence and respond to those of their partners, with control over sampling design parameters such as the number of individuals, partners, and repeated dyads. The simulation framework allows flexible control over variation and correlation in mean trait values, social responsiveness, and social impact, making it suitable for research on interacting phenotypes and on direct and indirect genetic effects ('DGEs and IGEs'). The package also includes functions to fit and compare alternative models of social effects, including impactâ responsiveness, varianceâ partitioning, and trait-based models, and to summarise model performance in terms of bias and dispersion. For a more detailed description of the available models and impactâ responsiveness, see the accompanying article Wijnhorst et al. (2026) <doi:10.1093/jeb/voag013>.
Fetch data on targeted public investments from Plataforma +Brasil (SICONV) <http://plataformamaisbrasil.gov.br/>, the responsible system for requests, execution, and monitoring of federal discretionary transfers in Brazil.
This package provides a Bayesian framework for inferring influenza infection status from serial antibody measurements. Jointly estimates season-specific infection probabilities, antibody boosting and waning after infection, and baseline hemagglutination inhibition (HAI) titer distributions via Markov chain Monte Carlo (MCMC). Supports multi-season analysis and subgroup comparisons via a group_by interface. See Tsang et al. (2022) <doi:10.1038/s41467-022-29310-8> for methodological details.
We visualize the standard deviation of a data set as the size of a prism whose volume equals the total volume of several prisms made from the Empirical Cumulative Distribution Function.
Stochastic frontier analysis with advanced methods. In particular, it applies the approach proposed by Latruffe et al. (2017) <DOI:10.1093/ajae/aaw077> to estimate a stochastic frontier with technical inefficiency effects when one input is endogenous.
Generates cell-level cytokine activity estimates using relevant information from gene sets constructed with the CytoSig and the Reactome databases and scored using the modified Variance-adjusted Mahalanobis (VAM) framework for single-cell RNA-sequencing (scRNA-seq) data. CytoSig database is described in: Jiang at al., (2021) <doi:10.1038/s41592-021-01274-5>. Reactome database is described in: Gillespie et al., (2021) <doi:10.1093/nar/gkab1028>. The VAM method is outlined in: Frost (2020) <doi:10.1093/nar/gkaa582>.
This package provides functions to nonparametrically assess assumptions sufficient to prevent the surrogate paradox through hypothesis tests of stochastic dominance, monotonicity of conditional mean functions, and non-negative residual treatment effect. Details are described in: Hsiao E, Tian L, and Parast L (2026). "Avoiding the surrogate paradox: an empirical framework for assessing assumptions." Journal of Nonparametric Statistics <doi:10.1080/10485252.2025.2498609>. There are also functions to assess resilience to the surrogate paradox via calculation of the resilience probability, the resilience bound, and the resilience set. Details will be available in Hsiao E, Tian L, and Parast L, "Resilience Measures for the Surrogate Paradox" (Under Review). Lastly, there is a function to assess resilience to the surrogate paradox in the met-analytic setting, described in Hsiao E and Parast L, "A Functional-Class Meta-Analytic Framework for Quantifying Surrogate Resilience" (Under Review). A tutorial for this package can be found at <https://www.laylaparast.com/surrogateparadoxtest>.
Calculates a degree of spatial association between regionalizations or categorical maps using the information-theoretical V-measure (Nowosad and Stepinski (2018) <doi:10.1080/13658816.2018.1511794>). It also offers an R implementation of the MapCurve method (Hargrove et al. (2006) <doi:10.1007/s10109-006-0025-x>).
Static analysis for R scientific data analysis code. Flags patterns that often correspond to hidden scientific commitments -- silent error swallowing, smuggled defaults, label leakage in selection-stage code, magic-eps floors in BIC formulas, and shadow-overwrite of sourced helpers. Designed for agentic coding workflows; high recall over precision; structured ANALYSIS_OK waivers as the audit trail.
This package provides tools to calculate the alpha parameter of the Weibull distribution, given beta and the age-specific fertility of a species, so that the population remains stable and stationary. Methods are inspired by "Survival profiles from linear models versus Weibull models: Estimating stable and stationary population structures for Pleistocene large mammals" (Martà n-González et al. 2019) <doi:10.1016/j.jasrep.2019.03.031>.
Full text, in data frames containing one row per verse, of the Standard Works of The Church of Jesus Christ of Latter-day Saints (LDS). These are the Old Testament, (KJV), the New Testament (KJV), the Book of Mormon, the Doctrine and Covenants, and the Pearl of Great Price.
This package provides a set of function that implements for seasonal multivariate time series analysis based on Seasonal Generalized Space Time Autoregressive with Seemingly Unrelated Regression (S-GSTAR-SUR) Model by Setiawan(2016)<https://www.researchgate.net/publication/316517889_S-GSTAR-SUR_model_for_seasonal_spatio_temporal_data_forecasting>.
This package performs multiple testing corrections that take specific structure of hypotheses into account, as described in Sankaran & Holmes (2014) <doi:10.18637/jss.v059.i13>.
Starting from a given object representing a fitted model (within a certain set of model classes) whose (non-)linear predictor includes some ordered factor(s) among the explanatory variables, a new model is constructed and fitted where each named factor is replaced by a single numeric score, suitably chosen so that the new variable produces a fit comparable with the standard methodology based on a set of polynomial contrasts. Two variants of the present approach have been developed, one in each of the next references: Azzalini (2023) <doi:10.1002/sta4.624>, (2024) <doi:10.48550/arXiv.2406.15933>.
Estimation of robust estimators for multi-group and spatial data including the casewise robust Spatially Smoothed Minimum Regularized Determinant (ssMRCD) estimator and its usage for local outlier detection as described in Puchhammer and Filzmoser (2023) <doi:10.1080/10618600.2023.2277875> as well as for sparse robust PCA for multi-source data described in Puchhammer, Wilms and Filzmoser (2024) <doi:10.48550/arXiv.2407.16299>. Moreover, a cellwise robust multi-group Gaussian mixture model (MG-GMM) is implemented as described in Puchhammer, Wilms and Filzmoser (2024) <doi:10.48550/arXiv.2504.02547>. Included are also complementary visualization and parameter tuning tools.
Sequences sampled at different time points can be used to infer molecular phylogenies on natural time scales, but if the sequences records inaccurate sampling times, that are not the actual sampling times, then it will affect the molecular phylogenetic analysis. This shiny application helps exploring temporal characteristics of the evolutionary trees through linear regression analysis and with the ability to identify and remove incorrect labels. The method was extended to support exploring other phylogenetic signals under strict and relaxed models.
Calculates vote-specific and traditional Shapley-Owen power indices (vs-SOVs and SOVs) for spatial voting games in one to four dimensions. Evaluates voter influence through an a posteriori analysis of relative preferences. Supports weighted voting and various voting thresholds. Compatible with ideal point estimates from NOMINATE, Optimal Classification, and MCMCpack'. The method builds on Bibina and Dougherty (2025) <doi:10.2139/ssrn.6324519>.
Builds regression trees and random forests for longitudinal or functional data using a spline projection method. Implements and extends the work of Yu and Lambert (1999) <doi:10.1080/10618600.1999.10474847>. This method allows trees and forests to be built while considering either level and shape or only shape of response trajectories.