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This package implements wavelet-based approaches for describing population admixture. Principal Components Analysis (PCA) is used to define the population structure and produce a localized admixture signal for each individual. Wavelet summaries of the PCA output describe variation present in the data and can be related to population-level demographic processes. For more details, see J Sanderson, H Sudoyo, TM Karafet, MF Hammer and MP Cox. 2015. Reconstructing past admixture processes from local genomic ancestry using wavelet transformation. Genetics 200:469-481 <doi:10.1534/genetics.115.176842>.
R codes for the (adaptive) Sum of Powered Score ('SPU and aSPU') tests, inverse variance weighted Sum of Powered score ('SPUw and aSPUw') tests and gene-based and some pathway based association tests (Pathway based Sum of Powered Score tests ('SPUpath'), adaptive SPUpath ('aSPUpath') test, GEEaSPU test for multiple traits - single SNP (single nucleotide polymorphism) association in generalized estimation equations, MTaSPUs test for multiple traits - single SNP association with Genome Wide Association Studies ('GWAS') summary statistics, Gene-based Association Test that uses an extended Simes procedure ('GATES'), Hybrid Set-based Test ('HYST') and extended version of GATES test for pathway-based association testing ('GATES-Simes'). ). The tests can be used with genetic and other data sets with covariates. The response variable is binary or quantitative. Summary; (1) Single trait-'SNP set association with individual-level data ('aSPU', aSPUw', aSPUr'), (2) Single trait-'SNP set association with summary statistics ('aSPUs'), (3) Single trait-pathway association with individual-level data ('aSPUpath'), (4) Single trait-pathway association with summary statistics ('aSPUsPath'), (5) Multiple traits-single SNP association with individual-level data ('GEEaSPU'), (6) Multiple traits- single SNP association with summary statistics ('MTaSPUs'), (7) Multiple traits-'SNP set association with summary statistics('MTaSPUsSet'), (8) Multiple traits-pathway association with summary statistics('MTaSPUsSetPath').
Download Alphavantage financial data <https://www.alphavantage.co/documentation/> to reduced data.table objects. Includes support functions to extract and simplify complex data returned from API calls.
This package provides a summarization method to estimate allele-specific copy number signals for Affymetrix SNP microarrays using non-negative matrix factorization (NMF).
This package provides a pipeable, transparent implementation of areal weighted interpolation with support for interpolating multiple variables in a single function call. These tools provide a full-featured workflow for validation and estimation that fits into both modern data management (e.g. tidyverse) and spatial data (e.g. sf) frameworks.
Point-scale variogram deconvolution from irregular/regular spatial support according to Goovaerts, P., (2008) <doi: 10.1007/s11004-007-9129-1>; ordinary area-to-area (co)Kriging and area-to-point (co)Kriging.
This package provides functions to compute upper Clopper-Pearson confidence limits of early life failure probabilities and required sample sizes of burn-in studies under further available information, e.g. from other products or technologies.
This package implements Bayesian estimation and inference for alpha-mixture survival models, including Weibull and Exponential based components, with tools for simulation and posterior summaries. The methods target applications in reliability and biomedical survival analysis. The package implements Bayesian estimation for the alpha-mixture methodology introduced in Asadi et al. (2019) <doi:10.1017/jpr.2019.72>.
In social and educational settings, the use of Artificial Intelligence (AI) is a challenging task. Relevant data is often only available in handwritten forms, or the use of data is restricted by privacy policies. This often leads to small data sets. Furthermore, in the educational and social sciences, data is often unbalanced in terms of frequencies. To support educators as well as educational and social researchers in using the potentials of AI for their work, this package provides a unified interface for neural nets in PyTorch to deal with natural language problems. In addition, the package ships with a shiny app, providing a graphical user interface. This allows the usage of AI for people without skills in writing python/R scripts. The tools integrate existing mathematical and statistical methods for dealing with small data sets via pseudo-labeling (e.g. Cascante-Bonilla et al. (2020) <doi:10.48550/arXiv.2001.06001>) and imbalanced data via the creation of synthetic cases (e.g. Islam et al. (2012) <doi:10.1016/j.asoc.2021.108288>). Performance evaluation of AI is connected to measures from content analysis which educational and social researchers are generally more familiar with (e.g. Berding & Pargmann (2022) <doi:10.30819/5581>, Gwet (2014) <ISBN:978-0-9708062-8-4>, Krippendorff (2019) <doi:10.4135/9781071878781>). Estimation of energy consumption and CO2 emissions during model training is done with the python library codecarbon'. Finally, all objects created with this package allow to share trained AI models with other people.
This package provides functions to convert origin-destination data, represented as straight desire lines in the sf Simple Features class system, into JSON files that can be directly imported into A/B Street <https://www.abstreet.org>, a free and open source tool for simulating urban transport systems and scenarios of change <doi:10.1007/s10109-020-00342-2>.
This toolkit implements a numerical solution algorithm to invert a quality of life measure from observed data. Unlike the traditional Rosen-Roback measure, this measure accounts for mobility frictionsâ generated by idiosyncratic tastes and local ties â and trade frictions â generated by trade costs and non-tradable services, thereby reducing non-classical measurement error. The QoL measure is based on Ahlfeldt, Bald, Roth, Seidel (2024) <https://econpapers.repec.org/RePEc:boc:bocode:s459382> "Measuring Quality of Life under Spatial Frictions". When using this programme or the toolkit in your work, please cite the paper.
This package provides a simple client package for the Amazon Web Services ('AWS') Lambda API <https://aws.amazon.com/lambda/>.
This package provides a shiny application to assess statistical assumptions and guide users toward appropriate tests. The app is designed for researchers with minimal statistical training and provides diagnostics, plots, and test recommendations for a wide range of analyses. Many statistical assumptions are implemented using the package rstatix (Kassambara, 2019) <doi:10.32614/CRAN.package.rstatix> and performance (Lüdecke et al., 2021) <doi:10.21105/joss.03139>.
Converts legacy microscopy video formats (H.264/H.265, AVI/MJPEG, TIFF stacks) to the modern AV1 codec with minimal quality loss. Typical use cases include compressing large TIFF stacks from confocal microscopy and time-lapse experiments from hundreds of gigabytes to manageable sizes, re-encoding MP4 files exported from CellProfiler', ImageJ'/'Fiji', and microscope software with approximately 2x better compression at the same visual quality, and converting legacy AVI (MJPEG) and H.265 recordings to a single patent-free format suited for long-term archival. Automatically selects the best available backend: GPU hardware acceleration via Vulkan VK_KHR_VIDEO_ENCODE_AV1 (tested on AMD RDNA4; bundled headers, builds with any Vulkan SDK >= 1.3.275), with automatic fallback to CPU encoding through FFmpeg and SVT-AV1'. Audio tracks are preserved automatically. Provides a simple R API for batch conversion of entire experiment folders.
Epidemiological population dynamics models traditionally define a pathogen's virulence as the increase in the per capita rate of mortality of infected hosts due to infection. This package provides functions allowing virulence to be estimated by maximum likelihood techniques. The approach is based on the analysis of relative survival comparing survival in matching cohorts of infected vs. uninfected hosts (Agnew 2019) <doi:10.1101/530709>.
The agghoo procedure is an alternative to usual cross-validation. Instead of choosing the best model trained on V subsamples, it determines a winner model for each subsample, and then aggregates the V outputs. For the details, see "Aggregated hold-out" by Guillaume Maillard, Sylvain Arlot, Matthieu Lerasle (2021) <arXiv:1909.04890> published in Journal of Machine Learning Research 22(20):1--55.
Create Tables for Reporting Clinical Trials. Calculates descriptive statistics and hypothesis tests, arranges the results in a table ready for reporting with LaTeX, HTML or Word.
This package provides a web framework inspired by express.js to build any web service from multi-page websites to RESTful application programming interfaces.
This package provides tools to perform model selection alongside estimation under Linear, Logistic, Negative binomial, Quantile, and Skew-Normal regression. Under the spike-and-slab method, a probability for each possible model is estimated with the posterior mean, credibility interval, and standard deviation of coefficients and parameters under the most probable model.
RStudio allows to show and navigate for the outline of a R Markdown file, but not for R Markdown projects with multiple files. For this reason, I have developed several RStudio addins capable of show project outline. Each addin is specialized in showing projects of different types: R Markdown project, bookdown package project and LaTeX project. There is a configuration file that allows you to customize additional searches.
Allows the user to implement an address search auto completion menu on shiny text inputs. This is done using the Algolia Places JavaScript library. See <https://community.algolia.com/places/>.
The adapted pair correlation function transfers the concept of the pair correlation function from point patterns to patterns of objects of finite size and irregular shape (e.g. lakes within a country). The pair correlation function describes the spatial distribution of objects, e.g. random, aggregated or regularly spaced. This is a reimplementation of the method suggested by Nuske et al. (2009) <doi:10.1016/j.foreco.2009.09.050> using the library GEOS <doi:10.5281/zenodo.11396894>.
Interact with the Attentional Control Data Collection (ACDC) or the Truth Effect Database (TED). Download the databases using download_acdc() or download_ted(), connect to the database via connect_to_db(), set filter arguments via add_argument() and query the database via query_db().
This package provides functions for estimating the attributable burden of disease due to risk factors. The posterior simulation is performed using arm::sim as described in Gelman, Hill (2012) <doi:10.1017/CBO9780511790942> and the attributable burden method is based on Nielsen, Krause, Molbak <doi:10.1111/irv.12564>.