Calculates the sample size needed for evaluating a diagnostic test based on sensitivity, specificity, prevalence, and desired precision. Based on Buderer (1996) <doi:10.1111/j.1553-2712.1996.tb03538.x>.

This package provides several datasets useful for processing and analysis of text in Turkish from an online shopping platform.

R interface to Apache Spark, a fast and general engine for big data processing, see <https://spark.apache.org/>. This package supports connecting to local and remote Apache Spark clusters, provides a dplyr compatible back-end, and provides an interface to Spark's built-in machine learning algorithms.

Testing the mediation effect of multiple SNPs on an outcome through a mediator.

Import data from the STATcube REST API or from the open data portal of Statistics Austria. This package includes a client for API requests as well as parsing utilities for data which originates from STATcube'. Documentation about STATcubeR is provided by several vignettes included in the package as well as on the public pkgdown page at <https://statistikat.github.io/STATcubeR/>.

This package implements the Simple Non-Iterative Clustering algorithm for superpixel segmentation of multi-band images, as introduced by Achanta and Susstrunk (2017) <doi:10.1109/CVPR.2017.520>. Supports both standard image arrays and geospatial raster objects, with a design that can be extended to other spatial data frameworks. The algorithm groups adjacent pixels into compact, coherent regions based on spectral similarity and spatial proximity. A high-performance implementation supports images with arbitrary spectral bands.

This package provides SAS'-style IF/ELSE chains, independent IF rules, and DELETE logic for data.table', enabling clinical programmers to express Study Data Tabulation Model (SDTM) and Analysis Data Model (ADaM)-style derivations in familiar SAS-like syntax. Methods are informed by clinical data standards described in CDISC SDTM and ADaM implementation guides. See <https://www.cdisc.org/standards/foundational/sdtm> and <https://www.cdisc.org/standards/foundational/adam>.

This package provides a simple progress bar to use for basic and advanced users that suits all those who prefer procedural programming. It is especially useful for integration into markdown files thanks to the progress bar's customisable appearance.

Programmatic interface to the SNOTEL snow data (<https://www.nrcs.usda.gov/programs-initiatives/sswsf-snow-survey-and-water-supply-forecasting-program>). Provides easy downloads of snow data into your R work space or a local directory. Additional post-processing routines to extract snow season indexes are provided.

Sample size estimation for bio-equivalence trials is supported through a simulation-based approach that extends the Two One-Sided Tests (TOST) procedure. The methodology provides flexibility in hypothesis testing, accommodates multiple treatment comparisons, and accounts for correlated endpoints. Users can model complex trial scenarios, including parallel and crossover designs, intra-subject variability, and different equivalence margins. Monte Carlo simulations enable accurate estimation of power and type I error rates, ensuring well-calibrated study designs. The statistical framework builds on established methods for equivalence testing and multiple hypothesis testing in bio-equivalence studies, as described in Schuirmann (1987) <doi:10.1007/BF01068419>, Mielke et al. (2018) <doi:10.1080/19466315.2017.1371071>, Shieh (2022) <doi:10.1371/journal.pone.0269128>, and Sozu et al. (2015) <doi:10.1007/978-3-319-22005-5>. Comprehensive documentation and vignettes guide users through implementation and interpretation of results.

This package provides a comprehensive Shiny application for analyzing Whole Genome Duplication ('WGD') events. This package provides a user-friendly Shiny web application for non-experienced researchers to prepare input data and execute command lines for several well-known WGD analysis tools, including wgd', ksrates', i-ADHoRe', OrthoFinder', and Whale'. This package also provides the source code for experienced researchers to adjust and install the package to their own server. Key Features 1) Input Data Preparation This package allows users to conveniently upload and format their data, making it compatible with various WGD analysis tools. 2) Command Line Generation This package automatically generates the necessary command lines for selected WGD analysis tools, reducing manual errors and saving time. 3) Visualization This package offers interactive visualizations to explore and interpret WGD results, facilitating in-depth WGD analysis. 4) Comparative Genomics Users can study and compare WGD events across different species, aiding in evolutionary and comparative genomics studies. 5) User-Friendly Interface This Shiny web application provides an intuitive and accessible interface, making WGD analysis accessible to researchers and bioinformaticians of all levels.

Offers markdown output formats designed with various styles, allowing users to generate HTML reports tailored for scientific or machine learning showcase. The output has a contemporary appearance with vibrant visuals, providing numerous styles for effective highlighting. Created using the tufte <https://rstudio.github.io/tufte/> package code as a starting point.

This package provides methods for spatial risk calculations, focusing on efficient determination of the sum of observations within a circle of a given radius. These methods are particularly relevant for applications such as insurance, where recent European Commission regulations require the calculation of the maximum insured value of fire risk policies for all buildings that are partly or fully located within a 200 m radius. The underlying problem is described by Church (1974) <doi:10.1007/BF01942293>.

Quality control charts for survival outcomes. Allows users to construct the Continuous Time Generalized Rapid Response CUSUM (CGR-CUSUM) <doi:10.1093/biostatistics/kxac041>, the Biswas & Kalbfleisch (2008) <doi:10.1002/sim.3216> CUSUM, the Bernoulli CUSUM and the risk-adjusted funnel plot for survival data <doi:10.1002/sim.1970>. These procedures can be used to monitor survival processes for a change in the failure rate.

Parse Standard Schedules Information file (types 2 and 3) into a Data Frame. Can also expand schedules into flights.

Inference techniques for Fay Herriot Model.

Analysis of spatial relationships between cell types in spatial transcriptomics data. Spatial proximity is a critical factor in cell-cell communication. The package calculates nearest neighbor distances between specified cell types and provides visualization tools to explore spatial patterns. Applications include studying cell-cell interactions, immune microenvironment characterization, and spatial organization of tissues.

Algorithms to compute spherical k-means partitions. Features several methods, including a genetic and a fixed-point algorithm and an interface to the CLUTO vcluster program.

This package provides a Package for selecting variables for the joint modeling of mean and dispersion (including models for mixture experiments) based on hypothesis testing and the quality of model's fit. In each iteration of the selection process, a criterion for checking the goodness of fit is used as a filter for choosing the terms that will be evaluated by a hypothesis test. Pinto & Pereira (2021) <arXiv:2109.07978>.

Unequal granularity of cell type annotation makes it difficult to compare scRNA-seq datasets at scale. Leveraging the ontology system for defining cell type hierarchy, scOntoMatch aims to align cell type annotations to make them comparable across studies. The alignment involves two core steps: first is to trim the cell type tree within each dataset so each cell type does not have descendants, and then map cell type labels cross-studies by direct matching and mapping descendants to ancestors. Various functions for plotting cell type trees and manipulating ontology terms are also provided. In the Single Cell Expression Atlas hosted at EBI, a compendium of datasets with curated ontology labels are great inputs to this package.

This package provides a set of plotting methods for simmer trajectories and simulations.

Easy to use interfaces to a number of imputation methods that fit in the not-a-pipe operator of the magrittr package.

Contains, as a main contribution, a function to fit a regression model with possibly right, left or interval censored observations and with the error distribution expressed as a mixture of G-splines. Core part of the computation is done in compiled C++ written using the Scythe Statistical Library Version 0.3.

In Switzerland, the landscape of municipalities is changing rapidly mainly due to mergers. The Swiss Municipal Data Merger Tool automatically detects these mutations and maps municipalities over time, i.e. municipalities of an old state to municipalities of a new state. This functionality is helpful when working with datasets that are based on different spatial references. The package's idea and use case is discussed in the following article: <doi:10.1111/spsr.12487>.