This package provides estimations of the Receiver Operating Characteristic (ROC) curve and the Area Under the Curve (AUC) based on the two-stages mixed-subjects ROC curve estimator (Diaz-Coto et al. (2020) <doi:10.1515/ijb-2019-0097> and Diaz-Coto et al. (2020) <doi:10.1080/00949655.2020.1736071>).

This package implements a three-dimensional stochastic model of cancer growth and mutation similar to the one described in Waclaw et al. (2015) <doi:10.1038/nature14971>. Allows for interactive 3D visualizations of the simulated tumor. Provides a comprehensive summary of the spatial distribution of mutants within the tumor. Contains functions which create synthetic sequencing datasets from the generated tumor.

This package provides a fast and flexible set of tools for large scale estimation. It features many stochastic gradient methods, built-in models, visualization tools, automated hyperparameter tuning, model checking, interval estimation, and convergence diagnostics.

Shapley Value Regression for calculating the relative importance of independent variables in linear regression with avoiding the collinearity.

Toolbox containing a variety of spectral clustering tools functions. Among the tools available are the hierarchical spectral clustering algorithm, the Shi and Malik clustering algorithm, the Perona and Freeman algorithm, the non-normalized clustering, the Von Luxburg algorithm, the Partition Around Medoids clustering algorithm, a multi-level clustering algorithm, recursive clustering and the fast method for all clustering algorithm. As well as other tools needed to run these algorithms or useful for unsupervised spectral clustering. This toolbox aims to gather the main tools for unsupervised spectral classification. See <http://mawenzi.univ-littoral.fr/> for more information and documentation.

Algorithms to compute spherical k-means partitions. Features several methods, including a genetic and a fixed-point algorithm and an interface to the CLUTO vcluster program.

Bayesian clustering of spatial regions with similar functional shapes using spanning trees and latent Gaussian models. The method enforces spatial contiguity within clusters and supports a wide range of latent Gaussian models, including non-Gaussian likelihoods, via the R-INLA framework. The algorithm is based on Zhong, R., Chacón-Montalván, E. A., and Moraga, P. (2024) <doi:10.48550/arXiv.2407.12633>, extending the approach of Zhang, B., Sang, H., Luo, Z. T., and Huang, H. (2023) <doi:10.1214/22-AOAS1643>. The package includes tools for model fitting, convergence diagnostics, visualization, and summarization of clustering results.

Spectra viewer, organizer, data preparation and property blocks from within R or stand-alone. Binary (application) part is installed separately using spnInstallApp() from spectrino package.

The Subsemble algorithm is a general subset ensemble prediction method, which can be used for small, moderate, or large datasets. Subsemble partitions the full dataset into subsets of observations, fits a specified underlying algorithm on each subset, and uses a unique form of k-fold cross-validation to output a prediction function that combines the subset-specific fits. An oracle result provides a theoretical performance guarantee for Subsemble. The paper, "Subsemble: An ensemble method for combining subset-specific algorithm fits" is authored by Stephanie Sapp, Mark J. van der Laan & John Canny (2014) <doi:10.1080/02664763.2013.864263>.

This package provides tools to decompose (transformed) spatial connectivity matrices and perform supervised or unsupervised semiparametric spatial filtering in a regression framework. The package supports unsupervised spatial filtering in standard linear as well as some generalized linear regression models.

This package provides tools and methods to simulate populations for surveys based on auxiliary data. The tools include model-based methods, calibration and combinatorial optimization algorithms, see Templ, Kowarik and Meindl (2017) <doi:10.18637/jss.v079.i10>) and Templ (2017) <doi:10.1007/978-3-319-50272-4>. The package was developed with support of the International Household Survey Network, DFID Trust Fund TF011722 and funds from the World bank.

Based on Shapley values to explain multivariate outlyingness and to detect and impute cellwise outliers. Includes implementations of methods described in Mayrhofer and Filzmoser (2023) <doi:10.1016/j.ecosta.2023.04.003>.

This package provides a workflow based on machine learning methods to construct and compare single-cell gene regulatory networks (scGRN) using single-cell RNA-seq (scRNA-seq) data collected from different conditions. Uses principal component regression, tensor decomposition, and manifold alignment, to accurately identify even subtly shifted gene expression programs. See <doi:10.1016/j.patter.2020.100139> for more details.

Load and export SomaScan data via the SomaLogic Operating Co., Inc. structured text file called an ADAT ('*.adat'). For file format see <https://github.com/SomaLogic/SomaLogic-Data/blob/main/README.md>. The package also exports auxiliary functions for manipulating, wrangling, and extracting relevant information from an ADAT object once in memory.

Small area estimation unit level models (Battese-Harter-Fuller model) with a Bayesian Hierarchical approach. See also Rao & Molina (2015, ISBN:978-1-118-73578-7) and Battese et al. (1988) <doi:10.1080/01621459.1988.10478561>.

Takea Semantic Structure Analysis (TSSA) and Sakai Sequential Relation Analysis (SSRA) for polytomous items. Package includes functions for generating a sequential relation table and a treegram to visualize the sequential relations between pairs of items.

Isolation forest is anomaly detection method introduced by the paper Isolation based Anomaly Detection (Liu, Ting and Zhou <doi:10.1145/2133360.2133363>).

This package provides standard load profiles (SLPs) for electricity and gas published by the German Association of Energy and Water Industries (BDEW Bundesverband der Energie- und Wasserwirtschaft e.V.) in a tidy format. The electricity profiles cover the 1999 profiles â households (H0), commercial (G0â G6), and agriculture (L0â L2) â and the updated 2025 profiles (H25, G25, L25, P25, S25), which additionally represent households with photovoltaic systems and battery storage. An interface generates an electricity load profile over a user-defined date range. A second interface generates daily standard load profiles for gas using the synthetic SigLinDe method. More information on the data and methodology for electricity is described in "Standardlastprofile Strom", <https://www.bdew.de/energie/standardlastprofile-strom/>, and for gas in "Standardlastprofile Gas", <https://www.bdew.de/energie/standardlastprofile-gas/>.

Loads and manages statistical genetics data objects including reference panels, genotypes, LD matrices, annotations, and summary statistics. Follows the statgen specification for use across Python', R', and MATLAB'/'Octave runtimes.

An R shiny user interface for the nlmixr2 (Fidler et al (2019) <doi:10.1002/psp4.12445>) package, designed to simplify the modeling process for users. Additionally, this package includes supplementary functions to further enhances the usage of nlmixr2'.

Simulation extrapolation and inverse probability weighted generalized estimating equations method for longitudinal data with missing observations and measurement error in covariates. References: Yi, G. Y. (2008) <doi:10.1093/biostatistics/kxm054>; Cook, J. R. and Stefanski, L. A. (1994) <doi:10.1080/01621459.1994.10476871>; Little, R. J. A. and Rubin, D. B. (2002, ISBN:978-0-471-18386-0).

Created for population health analytics and monitoring. The functions in this package work best when working with patient level Master Patient Index-like datasets . Built to be used by NHS bodies and other health service providers.

Simple class to hold contents of a SMET file as specified in Bavay (2021) <https://code.wsl.ch/snow-models/meteoio/-/blob/master/doc/SMET_specifications.pdf>. There numerical meteorological measurements are all based on MKS (SI) units and timestamp is standardized to UTC time.

This package provides a tool to plot data with a large sample size using shiny and plotly'. Relatively small samples are obtained from the original data using a specific algorithm. The samples are updated according to a user-defined x range. Jonas Van Der Donckt, Jeroen Van Der Donckt, Emiel Deprost (2022) <https://github.com/predict-idlab/plotly-resampler>.