This package implements the following approaches for multidimensional scaling (MDS) based on stress minimization using majorization (smacof): ratio/interval/ordinal/spline MDS on symmetric dissimilarity matrices, MDS with external constraints on the configuration, individual differences scaling (idioscal, indscal), MDS with spherical restrictions, and ratio/interval/ordinal/spline unfolding (circular restrictions, row-conditional). Various tools and extensions like jackknife MDS, bootstrap MDS, permutation tests, MDS biplots, gravity models, unidimensional scaling, drift vectors (asymmetric MDS), classical scaling, and Procrustes are implemented as well.

This package implements exact, normally approximated, and sampling-based sensitivity analysis for observational studies with contingency tables. Includes exact (kernel-based), normal approximation, and sequential importance sampling (SIS) methods using Rcpp for computational efficiency. The methods build upon the framework introduced in Rosenbaum (2002) <doi:10.1007/978-1-4757-3692-2> and the generalized design sensitivity framework developed by Chiu (2025) <doi:10.48550/arXiv.2507.17207>.

Constructs cell-typeâ specific gene regulatory networks from single-cell RNA-sequencing data. The method implements the SCORPION algorithm, which first aggregates individual cells into super-cells and then applies PANDA (Passing Attributes between Networks for Data Assimilation) to infer transcription factorâ target regulatory relationships. It also provides statistical methods for differential edge analysis.

This package contains functions to perform various models and methods for test equating (Kolen and Brennan, 2014 <doi:10.1007/978-1-4939-0317-7> ; Gonzalez and Wiberg, 2017 <doi:10.1007/978-3-319-51824-4> ; von Davier et. al, 2004 <doi:10.1007/b97446>). It currently implements the traditional mean, linear and equipercentile equating methods. Both IRT observed-score and true-score equating are also supported, as well as the mean-mean, mean-sigma, Haebara and Stocking-Lord IRT linking methods. It also supports newest methods such that local equating, kernel equating (using Gaussian, logistic, Epanechnikov, uniform and adaptive kernels) with presmoothing, and IRT parameter linking methods based on asymmetric item characteristic functions. Functions to obtain both standard error of equating (SEE) and standard error of equating differences between two equating functions (SEED) are also implemented for the kernel method of equating.

The <http://standartox.uni-landau.de> database offers cleaned, harmonized and aggregated ecotoxicological test data, which can be used for assessing effects and risks of chemical concentrations found in the environment.

This package provides a comprehensive statistical toolbox for National Statistics Institutes (INS) in Africa. Provides functions for survey data import ('KoboToolbox', ODK', CSPro', Excel', Stata', SPSS'), data processing and validation, weighted statistical analysis (descriptive statistics, cross-tabulations, regression, Human Development Index (HDI), Multidimensional Poverty Index (MPI) following Alkire and Foster (2011) <doi:10.1093/oep/gpr051>, inequalities), visualization (age pyramids, thematic maps, official charts) and dissemination ('SDMX export, DDI metadata, anonymization, Word/PDF reports). Designed to work in resource-constrained environments, offline and in French.

The code computes the structural intervention distance (SID) between a true directed acyclic graph (DAG) and an estimated DAG. Definition and details about the implementation can be found in J. Peters and P. Bühlmann: "Structural intervention distance (SID) for evaluating causal graphs", Neural Computation 27, pages 771-799, 2015 <doi:10.1162/NECO_a_00708>.

This package provides routines to check identifiability of linear structural equation models and factor analysis models. The routines are based on the graphical representation of structural equation models.

Develop outstanding shiny apps for iOS and Android as well as beautiful shiny gadgets. shinyMobile is built on top of the latest Framework7 template <https://framework7.io>. Discover 14 new input widgets (sliders, vertical sliders, stepper, grouped action buttons, toggles, picker, smart select, ...), 2 themes (light and dark), 12 new widgets (expandable cards, badges, chips, timelines, gauges, progress bars, ...) combined with the power of server-side notifications such as alerts, modals, toasts, action sheets, sheets (and more) as well as 3 layouts (single, tabs and split).

Simulation methods to study the effect of management policies on efforts to restore populations back to their original genetic composition. Allows for single-scenario simulation and for optimization of specific chosen scenarios. Further information can be found in Hernandez, Janzen and Lavretsky (2023) <doi:10.1111/1755-0998.13892>.

This is a collection of various kinds of data with broad uses for teaching. My students, and academics like me who teach the same topics I teach, should find this useful if their teaching workflow is also built around the R programming language. The applications are multiple but mostly cluster on topics of statistical methodology, international relations, and political economy.

We propose a novel two-step procedure to combine epidemiological data obtained from diverse sources with the aim to quantify risk factors affecting the probability that an individual develops certain disease such as cancer. See Hui Huang, Xiaomei Ma, Rasmus Waagepetersen, Theodore R. Holford, Rong Wang, Harvey Risch, Lloyd Mueller & Yongtao Guan (2014) A New Estimation Approach for Combining Epidemiological Data From Multiple Sources, Journal of the American Statistical Association, 109:505, 11-23, <doi:10.1080/01621459.2013.870904>.

This package implements an ensemble machine learning approach to predict the sporulation potential of metagenome-assembled genomes (MAGs) from uncultivated Firmicutes based on the presence/absence of sporulation-associated genes.

This package provides a computing tool is developed to automated identify somatic mutation-driven immune cells. The operation modes including: i) inferring the relative abundance matrix of tumor-infiltrating immune cells and integrating it with a particular gene mutation status, ii) detecting differential immune cells with respect to the gene mutation status and converting the abundance matrix of significant differential immune cell into two binary matrices (one for up-regulated and one for down-regulated), iii) identifying somatic mutation-driven immune cells by comparing the gene mutation status with each immune cell in the binary matrices across all samples, and iv) visualization of immune cell abundance of samples in different mutation status..

This package provides tools for simulating, analysing, and fitting mobility-based SEAIR (Susceptible-Exposed-Asymptomatic-Infectious-Recovered) compartmental epidemic models with heterogeneous individual mobility. Each individual carries a fixed mobility trait that scales susceptibility and infectiousness through a rank-one kernel, extending the mobility-based compartmental framework of Jiang et al. (2025) <doi:10.1137/24M1691557> by adding a latent stage and a behavioural split between asymptomatic and symptomatic infectiousness. Provides a numerical solver for the underlying partial differential equation system, closed-form computation of the basic reproduction number R0 and the final epidemic size, and a parametric least-squares routine for recovering the mobility distribution from an observed aggregate symptomatic time series.

Create Interactive Graph (Network) Visualizations. shinyCyJS can be used in Shiny apps or viewed from Rstudio Viewer. shinyCyJS includes API to build Graph model like node or edge with customized attributes for R. shinyCyJS is built with cytoscape.js and htmlwidgets R package.

This package provides a compact schema domain-specific language for inferring, editing, and validating R data structures with checkmate checks. Schemas can be serialized to and restored from JSON for storage and review. A generated standalone bundle supports vendoring the schema tools into other R packages.

An implementation of sensitivity analysis for phylogenetic comparative methods. The package is an umbrella of statistical and graphical methods that estimate and report different types of uncertainty in PCM: (i) Species Sampling uncertainty (sample size; influential species and clades). (ii) Phylogenetic uncertainty (different topologies and/or branch lengths). (iii) Data uncertainty (intraspecific variation and measurement error).

By binding R functions and the Highcharts <http://www.highcharts.com/> charting library, sankeywheel package provides a simple way to draw dependency wheels and sankey diagrams.

Processing and analysis of field collected or simulated sprinkler system catch data (depths) to characterize irrigation uniformity and efficiency using standard and other measures. Standard measures include the Christiansen coefficient of uniformity (CU) as found in Christiansen, J.E.(1942, ISBN:0138779295, "Irrigation by Sprinkling"); and distribution uniformity (DU), potential efficiency of the low quarter (PELQ), and application efficiency of the low quarter (AELQ) that are implementations of measures of the same notation in Keller, J. and Merriam, J.L. (1978) "Farm Irrigation System Evaluation: A Guide for Management" <https://pdf.usaid.gov/pdf_docs/PNAAG745.pdf>. spreval::DU.lh is similar to spreval::DU but is the distribution uniformity of the low half instead of low quarter as in DU. spreval::PELQT is a version of spreval::PELQ adapted for traveling systems instead of lateral move or solid-set sprinkler systems. The function spreval::eff is analogous to the method used to compute application efficiency for furrow irrigation presented in Walker, W. and Skogerboe, G.V. (1987,ISBN:0138779295, "Surface Irrigation: Theory and Practice"),that uses piecewise integration of infiltrated depth compared against soil-moisture deficit (SMD), when the argument "target" is set equal to SMD. The other functions contained in the package provide graphical representation of sprinkler system uniformity, and other standard univariate parametric and non-parametric statistical measures as applied to sprinkler system catch depths. A sample data set of field test data spreval::catchcan (catch depths) is provided and is used in examples and vignettes. Agricultural systems emphasized, but this package can be used for landscape irrigation evaluation, and a landscape (turf) vignette is included as an example application.

Fit additive mixed meta-analysis (AMMA) models, extending the mixmeta package <https://cran.r-project.org/package=mixmeta> to allow for spline-based meta-regression. Functions combine features of mgcv <https://cran.r-project.org/package=mgcv> for building spline components and mixmeta for estimating general mixed-effects meta-analysis models.

This package performs parametric and non-parametric estimation and simulation for multi-state discrete-time semi-Markov processes. For the parametric estimation, several discrete distributions are considered for the sojourn times: Uniform, Geometric, Poisson, Discrete Weibull and Negative Binomial. The non-parametric estimation concerns the sojourn time distributions, where no assumptions are done on the shape of distributions. Moreover, the estimation can be done on the basis of one or several sample paths, with or without censoring at the beginning or/and at the end of the sample paths. The implemented methods are described in Barbu, V.S., Limnios, N. (2008) <doi:10.1007/978-0-387-73173-5>, Barbu, V.S., Limnios, N. (2008) <doi:10.1080/10485250701261913> and Trevezas, S., Limnios, N. (2011) <doi:10.1080/10485252.2011.555543>. Estimation and simulation of discrete-time k-th order Markov chains are also considered.

Fits the regularization path of regression models (linear and logistic) with additively combined penalty terms. All possible combinations with Least Absolute Shrinkage and Selection Operator (LASSO), Smoothly Clipped Absolute Deviation (SCAD), Minimax Concave Penalty (MCP) and Exponential Penalty (EP) are supported. This includes Sparse Group LASSO (SGL), Sparse Group SCAD (SGS), Sparse Group MCP (SGM) and Sparse Group EP (SGE). For more information, see Buch, G., Schulz, A., Schmidtmann, I., Strauch, K., & Wild, P. S. (2024) <doi:10.1002/bimj.202200334>.

Sample size requirements calculation using three different Bayesian criteria in the context of designing an experiment to estimate the difference between two binomial proportions. Functions for calculation of required sample sizes for the Average Length Criterion, the Average Coverage Criterion and the Worst Outcome Criterion in the context of binomial observations are provided. In all cases, estimation of the difference between two binomial proportions is considered. Functions for both the fully Bayesian and the mixed Bayesian/likelihood approaches are provided. For reference see Joseph L., du Berger R. and Bélisle P. (1997) <doi:10.1002/(sici)1097-0258(19970415)16:7%3C769::aid-sim495%3E3.0.co;2-v>.