An efficient tool for fitting nested mixture models based on a shared set of atoms via Markov Chain Monte Carlo and variational inference algorithms. Specifically, the package implements the common atoms model (Denti et al., 2023), its finite version (similar to D'Angelo et al., 2023), and a hybrid finite-infinite model (D'Angelo and Denti, 2026). All models implement univariate nested mixtures with Gaussian kernels equipped with a normal-inverse gamma prior distribution on the parameters. Additional functions are provided to help analyze the results of the fitting procedure. References: Denti, Camerlenghi, Guindani, Mira (2023) <doi:10.1080/01621459.2021.1933499>, Dâ Angelo, Canale, Yu, Guindani (2023) <doi:10.1111/biom.13626>, Dâ Angelo, Denti (2026) <doi:10.1214/24-BA1458>.

R interface to Apache Spark, a fast and general engine for big data processing, see <https://spark.apache.org/>. This package supports connecting to local and remote Apache Spark clusters, provides a dplyr compatible back-end, and provides an interface to Spark's built-in machine learning algorithms.

Given bincount data from single-cell copy number profiling (segmented or unsegmented), estimates ploidy, and uses the ploidy estimate to scale the data to absolute copy numbers. Uses the modular quantogram proposed by Kendall (1986) <doi:10.1002/0471667196.ess2129.pub2>, modified by weighting segments according to confidence, and quantifying confidence in the estimate using a theoretical quantogram. Includes optional fused-lasso segmentation with the algorithm in Johnson (2013) <doi:10.1080/10618600.2012.681238>, using the implementation from glmgen by Arnold, Sadhanala, and Tibshirani.

Genomic alterations including single nucleotide substitution, copy number alteration, etc. are the major force for cancer initialization and development. Due to the specificity of molecular lesions caused by genomic alterations, we can generate characteristic alteration spectra, called signature (Wang, Shixiang, et al. (2021) <DOI:10.1371/journal.pgen.1009557> & Alexandrov, Ludmil B., et al. (2020) <DOI:10.1038/s41586-020-1943-3> & Steele Christopher D., et al. (2022) <DOI:10.1038/s41586-022-04738-6>). This package helps users to extract, analyze and visualize signatures from genomic alteration records, thus providing new insight into cancer study.

Implementation of hybrid STL decomposition based time delay neural network model for univariate time series forecasting. For method details see Jha G K, Sinha, K (2014). <doi:10.1007/s00521-012-1264-z>, Xiong T, Li C, Bao Y (2018). <doi:10.1016/j.neucom.2017.11.053>.

Generates region-specific Suess and Laws corrections for stable carbon isotope data from marine organisms collected between 1850 and 2023. Version 0.1.6 of SuessR contains four built-in regions: the Bering Sea ('Bering Sea'), the Aleutian archipelago ('Aleutian Islands'), the Gulf of Alaska ('Gulf of Alaska'), and the subpolar North Atlantic ('Subpolar North Atlantic'). Users can supply their own environmental data for regions currently not built into the package to generate corrections for those regions.

This package provides a lightweight runtime type system for R that enables developers to declare and enforce variable types during execution. Inspired by TypeScript', the package introduces intuitive syntax for annotating variables and validating data structures, helping catch type-related errors early and making R code more robust and easier to maintain.

This package provides facilities to implement and run population models of stage-structured species...

This package implements the methodological developments found in Hermes, van Heerwaarden, and Behrouzi (2023) <doi:10.48550/arXiv.2308.04325>, and allows for the statistical modeling of asymmetric between-location effects, as well as within-location effects using spatial autoregressive graphical models. The package allows for the generation of spatial weight matrices to capture asymmetric effects for strip-type intercropping designs, although it can handle any type of spatial data commonly found in other sciences.

It is often useful to produce short, quasi-unique identifiers (SQUIDs) without the benefit of a central authority to prevent duplication. Although Universally Unique Identifiers (UUIDs) provide for this, these are also unwieldy; for example, the most used UUID, version 4, is 36 characters long. SQUIDs are short (8 characters) at the expense of having more collisions, which can be mitigated by combining them with human-produced suffixes, yielding relatively brief, half human-readable, almost-unique identifiers (see for example the identifiers used for Decentralized Construct Taxonomies; Peters & Crutzen, 2024 <doi:10.15626/MP.2022.3638>). SQUIDs are the number of centiseconds elapsed since the beginning of 1970 converted to a base 30 system. This package contains functions to produce SQUIDs as well as convert them back into dates and times.

This package provides a dynamic model of the big-picture, whole ecosystem effects of hydrodynamics, temperature, nutrients, and fishing on continental shelf marine food webs. The package is described in: Heath, M.R., Speirs, D.C., Thurlbeck, I. and Wilson, R.J. (2020) <doi:10.1111/2041-210X.13510> StrathE2E2: An R package for modelling the dynamics of marine food webs and fisheries. 8pp.

Smooth a sequence of terra rasters using various algorithms (currently moving average, weighted moving average, and exponential smoothing). Also includes wrappers to smooth a vector time-series using these same algorithms. All smoothers use Rcpp implementations for performance.

Implementation of Small Area Estimation (SAE) using Hierarchical Bayesian (HB) Method when auxiliary variable measured with error under Beta Distribution. The rjags package is employed to obtain parameter estimates. For the references, see J.N.K & Molina (2015) <doi:10.1002/9781118735855>, Ybarra and Sharon (2008) <doi:10.1093/biomet/asn048>, and Ntzoufras (2009, ISBN-10: 1118210352).

Fit additive mixed meta-analysis (AMMA) models, extending the mixmeta package <https://cran.r-project.org/package=mixmeta> to allow for spline-based meta-regression. Functions combine features of mgcv <https://cran.r-project.org/package=mgcv> for building spline components and mixmeta for estimating general mixed-effects meta-analysis models.

An implementation of the full-likelihood Bayes factor (FLB) for evaluating segregation evidence in clinical medical genetics. The method was introduced by Thompson et al. (2003) <doi:10.1086/378100>. This implementation supports custom penetrance values and liability classes, and allows visualisations and robustness analysis as presented in Ratajska et al. (2023) <doi:10.1002/mgg3.2107>. See also the online app shinyseg', <https://chrcarrizosa.shinyapps.io/shinyseg>, which offers interactive segregation analysis with many additional features (Carrizosa et al. (2024) <doi:10.1093/bioinformatics/btae201>).

This package implements estimators for structured covariance matrices in the presence of pairwise and spatial covariates. Metodiev, Perrot-Dockès, Ouadah, Fosdick, Robin, Latouche & Raftery (2025) <doi:10.48550/arXiv.2411.04520>.

Simulate and plot general experimental crosses. The focus is on simulating genotypes with an aim towards flexibility rather than speed. Meiosis is simulated following the Stahl model, in which chiasma locations are the superposition of two processes: a proportion p coming from a process exhibiting no interference, and the remainder coming from a process following the chi-square model.

This package implements a Bayesian hierarchical model designed to identify skips in mobile menstrual cycle self-tracking on mobile apps. Future developments will allow for the inclusion of covariates affecting cycle mean and regularity, as well as extra information regarding tracking non-adherence. Main methods to be outlined in a forthcoming paper, with alternative models from Li et al. (2022) <doi:10.1093/jamia/ocab182>.

Creation of an individual claims simulator which generates various features of non-life insurance claims. An initial set of test parameters, designed to mirror the experience of an Auto Liability portfolio, were set up and applied by default to generate a realistic test data set of individual claims (see vignette). The simulated data set then allows practitioners to back-test the validity of various reserving models and to prove and/or disprove certain actuarial assumptions made in claims modelling. The distributional assumptions used to generate this data set can be easily modified by users to match their experiences. Reference: Avanzi B, Taylor G, Wang M, Wong B (2020) "SynthETIC: an individual insurance claim simulator with feature control" <doi:10.48550/arXiv.2008.05693>.

Computes scores of outlyingness for data sets consisting of nominal variables and includes various evaluation metrics for assessing performance of outlier identification algorithms producing scores of outlyingness. The scores of nominal outlyingness are computed based on the framework of Costa and Papatsouma (2025) <doi:10.48550/arXiv.2408.07463>.

Likelihood evaluations for stationary Gaussian time series are typically obtained via the Durbin-Levinson algorithm, which scales as O(n^2) in the number of time series observations. This package provides a "superfast" O(n log^2 n) algorithm written in C++, crossing over with Durbin-Levinson around n = 300. Efficient implementations of the score and Hessian functions are also provided, leading to superfast versions of inference algorithms such as Newton-Raphson and Hamiltonian Monte Carlo. The C++ code provides a Toeplitz matrix class packaged as a header-only library, to simplify low-level usage in other packages and outside of R.

Compose multiple dynamic failure rate distributions into series system distributions where the system hazard equals the sum of component hazards. Supports hazard, survival, cumulative distribution function, density, sampling, and maximum likelihood estimation fitting via the dfr_dist() class from flexhaz'. Series distributions implement the dist.structure protocol so structural queries (phi, min_paths, min_cuts, system_signature, structural importance, reliability, dual) and the importance measures from dist.structure work directly on serieshaz objects. Methods for series system reliability follow Barlow and Proschan (1975, ISBN:0898713692).

Procedure to optimally split a dataset for training and testing. SPlit is based on the method of support points, which is independent of modeling methods. Please see Joseph and Vakayil (2021) <doi:10.1080/00401706.2021.1921037> for details. This work is supported by U.S. National Science Foundation grant DMREF-1921873.

Discovers synergistic gene pairs in single-cell RNA-seq and spatial transcriptomics data. Unlike conventional pairwise co-expression analyses that rely on a single correlation metric, scPairs integrates 14 complementary metrics across five orthogonal evidence layers to compute a composite synergy score with optional permutation-based significance testing. The five evidence layers span cell-level co-expression (Pearson, Spearman, biweight midcorrelation, mutual information, ratio consistency), neighbourhood-aware smoothing (KNN-smoothed correlation, neighbourhood co-expression, cluster pseudo-bulk, cross-cell-type, neighbourhood synergy), prior biological knowledge (GO/KEGG co-annotation Jaccard, pathway bridge score), trans-cellular interaction, and spatial co-variation (Lee's L, co-location quotient). This multi-scale design enables researchers to move beyond simple co-expression towards a comprehensive characterisation of cooperative gene regulation at transcriptomic and spatial resolution. For more information, see the package documentation at <https://github.com/zhaoqing-wang/scPairs>.