Bootstrap based goodness-of-fit tests. It allows to perform rigorous statistical tests to check if a chosen model family is correct based on the marked empirical process. The implemented algorithms are described in (Dikta and Scheer (2021) <doi:10.1007/978-3-030-73480-0>) and can be applied to generalized linear models without any further implementation effort. As far as certain linearity conditions are fulfilled the resampling scheme are also applicable beyond generalized linear models. This is reflected in the software architecture which allows to reuse the resampling scheme by implementing only certain interfaces for models that are not supported natively by the package.

An advanced implementation of Bayesian Additive Regression Trees with expanded features for data analysis and visualization.

This package implements likelihood inference for early epidemic analysis. BETS is short for the four key epidemiological events being modeled: Begin of exposure, End of exposure, time of Transmission, and time of Symptom onset. The package contains a dataset of the trajectory of confirmed cases during the coronavirus disease (COVID-19) early outbreak. More detail of the statistical methods can be found in Zhao et al. (2020) <arXiv:2004.07743>.

Bayesian models are used to estimate effect sizes (e.g., gene expression changes, protein abundance differences, drug response effects) while accounting for uncertainty, small sample sizes, and complex experimental designs. However, Bayesian posteriors of models with many parameters are often difficult to interpret at a glance. One way to quickly identify important biological changes based on frequentist analysis are volcano plots (using fold-changes and p-values). Bayesian volcano plots bring together the explicit treatment of uncertainty in Bayesian models and the familiar visualization of volcano plots.

Reproducible and automated analysis of multiplex bead assays such as CBA (Morgan et al. 2004; <doi: 10.1016/j.clim.2003.11.017>), LEGENDplex (Yu et al. 2015; <doi: 10.1084/jem.20142318>), and MACSPlex (Miltenyi Biotec 2014; Application note: Data acquisition and analysis without the MACSQuant analyzer; <https://www.miltenyibiotec.com/upload/assets/IM0021608.PDF>). The package provides functions for streamlined reading of fcs files, and identification of bead clusters and analyte expression. The package eases the calculation of standard curves and the subsequent calculation of the analyte concentration.

Download typicality rating datasets, generate new stereotype-based typicality ratings using large language models via the Inference Providers API (<https://huggingface.co/docs/inference-providers>), and evaluate them against human-annotated validation data. Also includes functions to extract stereotype strength and base-rate items from typicality matrices. For more details see Beucler et al. (2025) <doi:10.31234/osf.io/eqrfu_v1>.

Implementation of the bootkmeans algorithm, a bootstrap augmented k-means algorithm that returns probabilistic cluster assignments. From paper by Ghashti, J.S., Andrews, J.L. Thompson, J.R.J., Epp, J. and H.S. Kochar (2025), "A bootstrap augmented k-means algorithm for fuzzy partitions" (Submitted).

Easily create tables from data frames/matrices. Create/manipulate tables row-by-row, column-by-column or cell-by-cell. Use common formatting/styling to output rich tables as HTML', HTML widgets or to Excel'.

Simulation and parameter estimation of multitype Bienayme - Galton - Watson processes.

Exposes the binary search functions of the C++ standard library (std::lower_bound, std::upper_bound) plus other convenience functions, allowing faster lookups on sorted vectors.

Bayesian dynamic borrowing with covariate adjustment via inverse probability weighting for simulations and data analyses in clinical trials. This makes it easy to use propensity score methods to balance covariate distributions between external and internal data. This methodology based on Psioda et al (2025) <doi:10.1080/10543406.2025.2489285>.

Noise filter based on determining the proportion of neighboring points. A false point will be rejected if it has only few neighbors, but accepted if the proportion of neighbors in a rectangular frame is high. The size of the rectangular frame as well as the cut-off value, i.e. of a minimum proportion of neighbor-points, may be supplied or can be calculated automatically. Originally designed for the cleaning of heart rates, but suitable for filtering any slowly-changing physiological variable.For more information see Signer (2010)<doi:10.1111/j.2041-210X.2009.00010.x>.

The Bloom Detecting Algorithm enables the detection of blooms within a time series of species abundance and extracts 22 phenological variables. For details, see Karasiewicz et al. (2022) <doi:10.3390/jmse10020174>.

This package provides a unified syntax for the simulation-based comparison of different single-stage basket trial designs with a binary endpoint and equal sample sizes in all baskets. Methods include the designs by Baumann et al. (2025) <doi:10.1080/19466315.2024.2402275>, Schmitt and Baumann (2025) <doi:10.1080/19466315.2025.2486231>, Fujikawa et al. (2020) <doi:10.1002/bimj.201800404>, Berry et al. (2020) <doi:10.1177/1740774513497539>, and Neuenschwander et al. (2016) <doi:10.1002/pst.1730>. For the latter two designs, the functions are mostly wrappers for functions provided by the package bhmbasket'.

This package provides functions to compute the asymptotic covariance matrices of mixing and unmixing matrix estimates of the following blind source separation (BSS) methods: symmetric and squared symmetric FastICA, regular and adaptive deflation-based FastICA, FOBI, JADE, AMUSE and deflation-based and symmetric SOBI. Also functions to estimate these covariances based on data are available.

This package provides a Bayesian, global planktic foraminifera core top calibration to modern sea-surface temperatures. Includes four calibration models, considering species-specific calibration parameters and seasonality.

This package provides functions to utilize a command line utility that does bulk inserts and exports from SQL Server databases.

The bias-corrected estimation methods for the receiver operating characteristics ROC surface and the volume under ROC surfaces (VUS) under missing at random (MAR) assumption.

Regression for data too large to fit in memory. This package functions exactly like the biglm package, but works with later versions of R.

Facilitates some of the analyses performed in studies of behavioral economic discounting. The package supports scoring of the 27-Item Monetary Choice Questionnaire (see Kaplan et al., 2016; <doi:10.1007/s40614-016-0070-9>), calculating k values (Mazur's simple hyperbolic and exponential) using nonlinear regression, calculating various Area Under the Curve (AUC) measures, plotting regression curves for both fit-to-group and two-stage approaches, checking for unsystematic discounting (Johnson & Bickel, 2008; <doi:10.1037/1064-1297.16.3.264>) and scoring of the minute discounting task (see Koffarnus & Bickel, 2014; <doi:10.1037/a0035973>) using the Qualtrics 5-trial discounting template (see the Qualtrics Minute Discounting User Guide; <doi:10.13140/RG.2.2.26495.79527>), which is also available as a .qsf file in this package.

This package provides methods for probabilistic reconciliation of hierarchical forecasts of time series. The available methods include analytical Gaussian reconciliation (Corani et al., 2021) <doi:10.1007/978-3-030-67664-3_13>, MCMC reconciliation of count time series (Corani et al., 2024) <doi:10.1016/j.ijforecast.2023.04.003>, Bottom-Up Importance Sampling (Zambon et al., 2024) <doi:10.1007/s11222-023-10343-y>, methods for the reconciliation of mixed hierarchies (Mix-Cond and TD-cond) (Zambon et al., 2024) <https://proceedings.mlr.press/v244/zambon24a.html>, analytical reconciliation with Bayesian treatment of the covariance matrix (Carrara et al., 2025) <doi: 10.48550/arXiv.2506.19554>.

The main function generateDataset() processes a user-supplied .R file that contains metadata parameters in order to generate actual data. The metadata parameters have to be structured in the form of metadata objects, the format of which is outlined in the package vignette. This approach allows to generate artificial data in a transparent and reproducible manner.

Under- and over-dispersed binary data are modeled using an extended Poisson process model (EPPM) appropriate for binary data. A feature of the model is that the under-dispersion relative to the binomial distribution only needs to be greater than zero, but the over-dispersion is restricted compared to other distributional models such as the beta and correlated binomials. Because of this, the examples focus on under-dispersed data and how, in combination with the beta or correlated distributions, flexible models can be fitted to data displaying both under- and over-dispersion. Using Generalized Linear Model (GLM) terminology, the functions utilize linear predictors for the probability of success and scale-factor with various link functions for p, and log link for scale-factor, to fit a variety of models relevant to areas such as bioassay. Details of the EPPM are in Faddy and Smith (2012) <doi:10.1002/bimj.201100214> and Smith and Faddy (2019) <doi:10.18637/jss.v090.i08>.

This package provides a new class of Bayesian meta-analysis models that incorporates a model for internal and external validity bias. In this way, it is possible to combine studies of diverse quality and different types. For example, we can combine the results of randomized control trials (RCTs) with the results of observational studies (OS).