Generate a palette of tints, shades or both from a single colour.

Obtaining relevant set of trait specific genes from gene expression data is important for clinical diagnosis of disease and discovery of disease mechanisms in plants and animals. This process involves identification of relevant genes and removal of redundant genes as much as possible from a whole gene set. This package returns the trait specific gene set from the high dimensional RNA-seq count data by applying combination of two conventional machine learning algorithms, support vector machine (SVM) and genetic algorithm (GA). GA is used to control and optimize the subset of genes sent to the SVM for classification and evaluation. Genetic algorithm uses repeated learning steps and cross validation over number of possible solution and selects the best. The algorithm selects the set of genes based on a fitness function that is obtained via support vector machines. Using SVM as the classifier performance and the genetic algorithm for feature selection, a set of trait specific gene set is obtained.

Simulation methods for phylogenetic trees where (i) all tips are sampled at one time point or (ii) tips are sampled sequentially through time. (i) For sampling at one time point, simulations are performed under a constant rate birth-death process, conditioned on having a fixed number of final tips (sim.bd.taxa()), or a fixed age (sim.bd.age()), or a fixed age and number of tips (sim.bd.taxa.age()). When conditioning on the number of final tips, the method allows for shifts in rates and mass extinction events during the birth-death process (sim.rateshift.taxa()). The function sim.bd.age() (and sim.rateshift.taxa() without extinction) allow the speciation rate to change in a density-dependent way. The LTT plots of the simulations can be displayed using LTT.plot(), LTT.plot.gen() and LTT.average.root(). TreeSim further samples trees with n final tips from a set of trees generated by the common sampling algorithm stopping when a fixed number m>>n of tips is first reached (sim.gsa.taxa()). This latter method is appropriate for m-tip trees generated under a big class of models (details in the sim.gsa.taxa() man page). For incomplete phylogeny, the missing speciation events can be added through simulations (corsim()). (ii) sim.rateshifts.taxa() is generalized to sim.bdsky.stt() for serially sampled trees, where the trees are conditioned on either the number of sampled tips or the age. Furthermore, for a multitype-branching process with sequential sampling, trees on a fixed number of tips can be simulated using sim.bdtypes.stt.taxa(). This function further allows to simulate under epidemiological models with an exposed class. The function sim.genespeciestree() simulates coalescent gene trees within birth-death species trees, and sim.genetree() simulates coalescent gene trees.

This package implements sentiment analysis using huggingface <https://huggingface.co> transformer zero-shot classification model pipelines for text and image data. The default text pipeline is Cross-Encoder's DistilRoBERTa <https://huggingface.co/cross-encoder/nli-distilroberta-base> and default image/video pipeline is Open AI's CLIP <https://huggingface.co/openai/clip-vit-base-patch32>. All other zero-shot classification model pipelines can be implemented using their model name from <https://huggingface.co/models?pipeline_tag=zero-shot-classification>.

This package performs maximum likelihood based estimation and inference on time to event data, possibly subject to non-informative right censoring. FitParaSurv() provides maximum likelihood estimates of model parameters and distributional characteristics, including the mean, median, variance, and restricted mean. CompParaSurv() compares the mean, median, and restricted mean survival experiences of two treatment groups. Candidate distributions include the exponential, gamma, generalized gamma, log-normal, and Weibull.

Targeted maximum likelihood estimation of point treatment effects (Targeted Maximum Likelihood Learning, The International Journal of Biostatistics, 2(1), 2006. This version automatically estimates the additive treatment effect among the treated (ATT) and among the controls (ATC). The tmle() function calculates the adjusted marginal difference in mean outcome associated with a binary point treatment, for continuous or binary outcomes. Relative risk and odds ratio estimates are also reported for binary outcomes. Missingness in the outcome is allowed, but not in treatment assignment or baseline covariate values. The population mean is calculated when there is missingness, and no variation in the treatment assignment. The tmleMSM() function estimates the parameters of a marginal structural model for a binary point treatment effect. Effect estimation stratified by a binary mediating variable is also available. An ID argument can be used to identify repeated measures. Default settings call SuperLearner to estimate the Q and g portions of the likelihood, unless values or a user-supplied regression function are passed in as arguments.

Allows users to quickly load multiple patients electrocardiographic (ECG) data at once and conduct relevant time analysis of heart rate variability (HRV) without manual edits from a physician or data cleaning specialist. The package provides the unique ability to iteratively filter, plot, and store time analysis results in a data frame while writing plots to a predefined folder. This streamlines the workflow for HRV analysis across multiple datasets. Methods are based on Rodrà guez-Liñares et al. (2011) <doi:10.1016/j.cmpb.2010.05.012>. Examples of applications using this package include Kwon et al. (2022) <doi:10.1007/s10286-022-00865-2> and Lawrence et al. (2023) <doi:10.1016/j.autneu.2022.103056>.

An aid for text mining in R, with a syntax that should be familiar to experienced R users. Provides a wrapper for several topic models that take similarly-formatted input and give similarly-formatted output. Has additional functionality for analyzing and diagnostics for topic models.

This package provides functions for interacting directly with the Taiwan Economic Journal API to offer data in R. For more information go to <https://api.tej.com.tw>.

Interactive laboratory of Time Series based in Box-Jenkins methodology.

Theme and colour palettes for The Globe and Mail's graphics. Includes colour and fill scale functions, colour palette helpers and a Globe-styled ggplot2 theme object.

This package provides a latent, quasi-independent truncation time is assumed to be linked with the observed dependent truncation time, the event time, and an unknown transformation parameter via a structural transformation model. The transformation parameter is chosen to minimize the conditional Kendall's tau (Martin and Betensky, 2005) <doi:10.1198/016214504000001538> or the regression coefficient estimates (Jones and Crowley, 1992) <doi:10.2307/2336782>. The marginal distribution for the truncation time and the event time are completely left unspecified. The methodology is applied to survival curve estimation and regression analysis.

Swift and seamless Single Sign-On (SSO) integration. Designed for effortless compatibility with popular Single Sign-On providers like Google and Microsoft, it streamlines authentication, enhancing both user experience and application security. Elevate your shiny applications for a simplified, unified, and secure authentication process.

Algorithms for accelerating the convergence of slow, monotone sequences from smooth, contraction mapping such as the EM and MM algorithms. It can be used to accelerate any smooth, linearly convergent acceleration scheme. A tutorial style introduction to this package is available in a vignette on the CRAN download page or, when the package is loaded in an R session, with vignette("turboEM").

Gives a number of functions to aid common data analysis processes and reporting statistical results in an RMarkdown file. Data analysis functions combine multiple base R functions used to describe simple bivariate relationships into a single, easy to use function. Reporting functions will return character strings to report p-values, confidence intervals, and hypothesis test and regression results. Strings will be LaTeX-formatted as necessary and will knit pretty in an RMarkdown document. The package also provides wrappers function in the tableone package to make the results knit-able.

Analyze telemetry datasets generalized to allow any technology. The filtering steps check for false positives caused by reflected transmissions from surfaces and false pings from other noise generating equipment. The filters are based on JSATS filtering algorithms found in package filteRjsats <https://CRAN.R-project.org/package=filteRjsats> but have been generalized to allow the user to define many of the filtering variables. Additionally, this package contains scripts used to help identify an optimal maximum blanking period as defined in Capello et al (2015) <doi:10.1371/journal.pone.0134002>. The functions were written according to their manuscript description, but have not been reviewed by the authors for accuracy. It is included here as is, without warranty.

Several functions to allow comparisons of data across different geographies, in particular for Canadian census data from different censuses.

An R interface to load testing data in the OMOP Common Data Model ('CDM'). An input file, csv or xlsx, can be converted to a CDMConnector object. This object can be used to execute and test studies that use the CDM <https://www.ohdsi.org/data-standardization/>.

The tsgc package provides comprehensive tools for the analysis and forecasting of epidemic trajectories. It is designed to model the progression of an epidemic over time while accounting for the various uncertainties inherent in real-time data. Underpinned by a dynamic Gompertz model, the package adopts a state space approach, using the Kalman filter for flexible and robust estimation of the non-linear growth pattern commonly observed in epidemic data. The reinitialization feature enhances the modelâ s ability to adapt to the emergence of new waves. The forecasts generated by the package are of value to public health officials and researchers who need to understand and predict the course of an epidemic to inform decision-making. Beyond its application in public health, the package is also a useful resource for researchers and practitioners in fields where the trajectories of interest resemble those of epidemics, such as innovation diffusion. The package includes functionalities for data preprocessing, model fitting, and forecast visualization, as well as tools for evaluating forecast accuracy. The core methodologies implemented in tsgc are based on well-established statistical techniques as described in Harvey and Kattuman (2020) <doi:10.1162/99608f92.828f40de>, Harvey and Kattuman (2021) <doi:10.1098/rsif.2021.0179>, and Ashby, Harvey, Kattuman, and Thamotheram (2024) <https://www.jbs.cam.ac.uk/wp-content/uploads/2024/03/cchle-tsgc-paper-2024.pdf>.

This package implements the Maximum Likelihood estimator for baseline, placebo, and treatment groups (three-group) experiments with non-compliance proposed by Gerber, Green, Kaplan, and Kern (2010).

Build customized transfer function and ARIMA models with multiple operators and parameter restrictions. Provides tools for model identification, estimation using exact or conditional maximum likelihood, diagnostic checking, automatic outlier detection, calendar effects, forecasting, and seasonal adjustment. The new version also supports unobserved component ARIMA model specification and estimation for structural time series analysis.

This package creates a local database of many commonly used taxonomic authorities and provides functions that can quickly query this data.

Estimates the time-varying (tv) parameters of the GARCH(1,1) model, enabling the modeling of non-stationary volatilities by allowing the model parameters to change gradually over time. The estimation and prediction processes are facilitated through the application of the Kalman filter and state-space equations. This package supports the estimation of tv parameters for various deterministic functions, which can be identified through exploratory analysis of different time periods or segments of return data. The methodology is grounded in the framework presented by Ferreira et al. (2017) <doi:10.1080/00949655.2017.1334778>.

This package performs Three-Mode Principal Components Analysis, which carries out Tucker Models.