This package provides a suite of utilities for working with the UK Biobank <https://www.ukbiobank.ac.uk/> Nuclear Magnetic Resonance spectroscopy (NMR) metabolomics data <https://biobank.ndph.ox.ac.uk/showcase/label.cgi?id=220>. Includes functions for extracting biomarkers from decoded UK Biobank field data, removing unwanted technical variation from biomarker concentrations, computing an extended set of lipid, fatty acid, and cholesterol fractions, and for re-deriving composite biomarkers and ratios after adjusting data for unwanted biological variation. For further details on methods see Ritchie SC et al. Sci Data (2023) <doi:10.1038/s41597-023-01949-y>.

The udder quarter infection data set contains infection times of individual cow udder quarters with Corynebacterium bovis (Laevens et al. 1997 <DOI:10.3168/jds.S0022-0302(97)76295-7>). Obviously, the four udder quarters are clustered within a cow, and udder quarters are sampled only approximately monthly, generating interval-censored data. The data set contains both covariates that change within a cow (e.g., front and rear udder quarters) and covariates that change between cows (e.g., parity [the number of previous calvings]). The correlation between udder infection times within a cow also is of interest, because this is a measure of the infectivity of the agent causing the disease. Various models have been applied to address the problem of interdependence for right-censored event times. These models, as applied to this data set, can be found back in the publications found in the reference list.

This package implements mixtures of unrestricted skew-t factor analyzer models via the EM algorithm.

This package provides a container for data used by the usmap package. The data used by usmap has been extracted into this package so that the file size of the usmap package can be reduced greatly. The data in this package will be updated roughly once per year as new map data files are provided by the US Census Bureau.

Extracts coordinates of an event location from text based on dictionaries of landmarks, roads, and areas. Only returns the location of an event of interest and ignores other location references; for example, if determining the location of a road traffic crash from the text "crash near [location 1] heading towards [location 2]", only the coordinates of "location 1" would be returned. Moreover, accounts for differences in spelling between how a user references a location and how a location is captured in location dictionaries. For more information on the algorithm, see Milusheva et al. (2021) <doi:10.1371/journal.pone.0244317>.

Complete work flow for the analysis of pharmacokinetic pharmacodynamic (PKPD), physiologically-based pharmacokinetic (PBPK) and systems pharmacology models including: creation of ordinary differential equation-based models, pooled parameter estimation, individual/population based simulations, rule-based simulations for clinical trial design and modeling assays, deployment with a customizable Shiny app, and non-compartmental analysis. System-specific analysis templates can be generated and each element includes integrated reporting with PowerPoint and Word'.

An educational toolkit for learning statistical concepts through interactive exploration. Provides functions for basic statistics (mean, variance, etc.) and probability distributions with step-by-step explanations and interactive learning modes. Each function can be used for simple calculations, detailed learning with explanations, or interactive practice with feedback.

This package provides a tool for checking how much information is disclosed when reporting summary statistics.

Concise TAP <http://testanything.org/> compliant unit testing package. Authored tests can be run using CMD check with minimal implementation overhead.

Detects values imported from spreadsheets that were auto-converted to Excel date serials and reconstructs the originally intended day.month decimals (for example, 30.3 that Excel displayed as 30/03/2025'). The functions work in a vectorized manner, preserve non-serial values, and support both the 1900 and 1904 date systems.

This package provides a comprehensive educational package combining clustering algorithms with detailed step-by-step explanations. Provides implementations of both traditional (hierarchical, k-means) and modern (Density-Based Spatial Clustering of Applications with Noise (DBSCAN), Gaussian Mixture Models (GMM), genetic k-means) clustering methods as described in Ezugwu et. al., (2022) <doi:10.1016/j.engappai.2022.104743>. Includes educational datasets highlighting different clustering challenges, based on scikit-learn examples (Pedregosa et al., 2011) <https://jmlr.csail.mit.edu/papers/v12/pedregosa11a.html>. Features detailed algorithm explanations, visualizations, and weighted distance calculations for enhanced learning.

Testing whether two discrete variables have a functional relationship under null distributions where the two variables are statistically independent with fixed marginal counts. The fast enumeration algorithm was based on (Nguyen et al. 2020) <doi:10.24963/ijcai.2020/372>.

Most universities use specific color combinations to express their unique brand identity. The unicol package provides the colors and color palettes of various universities for easy plotting and printing in R. We collect and provide a diverse range of color palettes for creating scientific visualizations.

Supervised classification methods, which (if asked) can provide step-by-step explanations of the algorithms used, as described in PK Josephine et. al., (2021) <doi:10.59176/kjcs.v1i1.1259>; and datasets to test them on, which highlight the strengths and weaknesses of each technique.

An engine for univariate time series forecasting using different regression models in an autoregressive way. The engine provides an uniform interface for applying the different models. Furthermore, it is extensible so that users can easily apply their own regression models to univariate time series forecasting and benefit from all the features of the engine, such as preprocessings or estimation of forecast accuracy.

Retrieve data from the UNESCO Institute for Statistics (UIS) API <https://api.uis.unesco.org/api/public/documentation/>. UIS provides public access to more than 4,000 indicators focusing on education, science and technology, culture, and communication.

Uniform Error Index is the weighted average of different error measures. Uniform Error Index utilizes output from different error function and gives more robust and stable error values. This package has been developed to compute Uniform Error Index from ten different loss function like Error Square, Square of Square Error, Quasi Likelihood Error, LogR-Square, Absolute Error, Absolute Square Error etc. The weights are determined using Principal Component Analysis (PCA) algorithm of Yeasin and Paul (2024) <doi:10.1007/s11227-023-05542-3>.

Verb-like functions to work with messy data, often derived from spreadsheets or parsed PDF tables. Includes functions for unwrapping values broken up across rows, relocating embedded grouping values, and to annotate meaningful formatting in spreadsheet files.

This package provides functions for converting between UK and US spellings of English words.

Predicts a smooth and continuous (individual) utility function from utility points, and computes measures of intensity for risk and higher-order risk measures (or any other measure computed with user-written function) based on this utility function and its derivatives according to the method introduced in Schneider (2017) <http://hdl.handle.net/21.11130/00-1735-0000-002E-E306-0>.

This package provides decorators, transformators, and utility functions to extend the teal framework for interactive data analysis applications. Implements methods for data visualization enhancement, statistical data transformations, and workflow integration tools. Designed to support clinical and pharmaceutical research workflows within the teal ecosystem through modular and reusable components.

Calculate unified measures that quantify the effect of a covariate on a binary dependent variable (e.g., for meta-analyses). This can be particularly important if the estimation results are obtained with different models/estimators (e.g., linear probability model, logit, probit, ...) and/or with different transformations of the explanatory variable of interest (e.g., linear, quadratic, interval-coded, ...). The calculated unified measures are: (a) semi-elasticities of linear, quadratic, or interval-coded covariates and (b) effects of linear, quadratic, interval-coded, or categorical covariates when a linear or quadratic covariate changes between distinct intervals, the reference category of a categorical variable or the reference interval of an interval-coded variable needs to be changed, or some categories of a categorical covariate or some intervals of an interval-coded covariate need to be grouped together. Approximate standard errors of the unified measures are also calculated. All methods that are implemented in this package are described in the vignette "Extracting and Unifying Semi-Elasticities and Effect Sizes from Studies with Binary Dependent Variables" that is included in this package.

Programmatic interface to access data from the UK Health Security Agency (UKHSA) Data Dashboard API. The package was originally based on the ukcovid19 package by Pouria Hadjibagheri and has been substantially rewritten and extended. For more information on the API, see <https://ukhsa-dashboard.data.gov.uk/access-our-data>.

Efficient Bayesian implementations of probit, logit, multinomial logit and binomial logit models. Functions for plotting and tabulating the estimation output are available as well. Estimation is based on Gibbs sampling where the Markov chain Monte Carlo algorithms are based on the latent variable representations and marginal data augmentation algorithms described in "Gregor Zens, Sylvia Frühwirth-Schnatter & Helga Wagner (2023). Ultimate Pólya Gamma Samplers â Efficient MCMC for possibly imbalanced binary and categorical data, Journal of the American Statistical Association <doi:10.1080/01621459.2023.2259030>".