Data analysis of proteomics experiments by mass spectrometry is supported by this collection of functions mostly dedicated to the analysis of (bottom-up) quantitative (XIC) data. Fasta-formatted proteomes (eg from UniProt Consortium <doi:10.1093/nar/gky1049>) can be read with automatic parsing and multiple annotation types (like species origin, abbreviated gene names, etc) extracted. Initial results from multiple software for protein (and peptide) quantitation can be imported (to a common format): MaxQuant (Tyanova et al 2016 <doi:10.1038/nprot.2016.136>), Dia-NN (Demichev et al 2020 <doi:10.1038/s41592-019-0638-x>), Fragpipe (da Veiga et al 2020 <doi:10.1038/s41592-020-0912-y>), ionbot (Degroeve et al 2021 <doi:10.1101/2021.07.02.450686>), MassChroq (Valot et al 2011 <doi:10.1002/pmic.201100120>), OpenMS (Strauss et al 2021 <doi:10.1038/nmeth.3959>), ProteomeDiscoverer (Orsburn 2021 <doi:10.3390/proteomes9010015>), Proline (Bouyssie et al 2020 <doi:10.1093/bioinformatics/btaa118>), AlphaPept (preprint Strauss et al <doi:10.1101/2021.07.23.453379>) and Wombat-P (Bouyssie et al 2023 <doi:10.1021/acs.jproteome.3c00636>. Meta-data provided by initial analysis software and/or in sdrf format can be integrated to the analysis. Quantitative proteomics measurements frequently contain multiple NA values, due to physical absence of given peptides in some samples, limitations in sensitivity or other reasons. Help is provided to inspect the data graphically to investigate the nature of NA-values via their respective replicate measurements and to help/confirm the choice of NA-replacement algorithms. Meta-data in sdrf-format (Perez-Riverol et al 2020 <doi:10.1021/acs.jproteome.0c00376>) or similar tabular formats can be imported and included. Missing values can be inspected and imputed based on the concept of NA-neighbours or other methods. Dedicated filtering and statistical testing using the framework of package limma <doi:10.18129/B9.bioc.limma> can be run, enhanced by multiple rounds of NA-replacements to provide robustness towards rare stochastic events. Multi-species samples, as frequently used in benchmark-tests (eg Navarro et al 2016 <doi:10.1038/nbt.3685>, Ramus et al 2016 <doi:10.1016/j.jprot.2015.11.011>), can be run with special options considering such sub-groups during normalization and testing. Subsequently, ROC curves (Hand and Till 2001 <doi:10.1023/A:1010920819831>) can be constructed to compare multiple analysis approaches. As detailed example the data-set from Ramus et al 2016 <doi:10.1016/j.jprot.2015.11.011>) quantified by MaxQuant, ProteomeDiscoverer, and Proline is provided with a detailed analysis of heterologous spike-in proteins.

Utilities for using a probability sample to reweight prevalence estimates calculated from the All of Us research program. Weighted estimates will still not be representative of the general U.S. population. However, they will provide an early indication for how unweighted estimates may be biased by the sampling bias in the All of Us sample.

It generates the roster of turn for an outlet which is flowing (water) 24X7 or 168 hours towards the area under command or agricutural area (to be irrigated). The area under command is differentially owned by different individual farmers. The Outlet runs for free of cost to irrigate the area under command 24X7. So, flow time of the outlet has to be divided based on an area owned by an individual farmer and the location of his land or farm. This roster is known as warabandi and its generation in agriculture practices is a very tedious task. Calculations of time in microseconds are more error-prone, especially whenever it is performed by hands. That division of flow time for an individual farmer can be calculated by warabandi'. However, it generates a full publishable report for an outlet and all the farmers who have farms subjected to be irrigated. It reduces error risk and makes a more reproducible roster. For more details about warabandi system you can found elsewhere in Bandaragoda DJ(1995) <https://publications.iwmi.org/pdf/H_17571i.pdf>.

This package implements the diagnostic "theta" developed in Poetscher and Preinerstorfer (2020) "How Reliable are Bootstrap-based Heteroskedasticity Robust Tests?" <arXiv:2005.04089>. This diagnostic can be used to detect and weed out bootstrap-based procedures that provably have size equal to one for a given testing problem. The implementation covers a large variety of bootstrap-based procedures, cf. the above mentioned article for details. A function for computing bootstrap p-values is provided.

This package provides a suite of routines for Weyl algebras. Notation follows Coutinho (1995, ISBN 0-521-55119-6, "A Primer of Algebraic D-Modules"). Uses disordR discipline (Hankin 2022 <doi:10.48550/arXiv.2210.03856>). To cite the package in publications, use Hankin 2022 <doi:10.48550/arXiv.2212.09230>.

This package provides the functions to perform a Welch's one-way Anova with fixed effects based on summary statistics (sample size, means, standard deviation) and the Games-Howell post hoc test for multiple comparisons and provides the effect size estimator adjusted omega squared. In addition sample size estimation can be computed based on Levy's method, and a Monte Carlo simulation is included to bootstrap residual normality and homoscedasticity Welch, B. L. (1951) <doi:10.1093/biomet/38.3-4.330> Kirk, R. E. (1996) <doi:10.1177/0013164496056005002> Carroll, R. M., & Nordholm, L. A. (1975) <doi:10.1177/001316447503500304> Albers, C., & Lakens, D. (2018) <doi:10.1016/j.jesp.2017.09.004> Games, P. A., & Howell, J. F. (1976) <doi:10.2307/1164979> Levy, K. J. (1978a) <doi:10.1080/00949657808810246> Show-Li, J., & Gwowen, S. (2014) <doi:10.1111/bmsp.12006>.

The weighted scores method and composite likelihood information criteria as an intermediate step for variable/correlation selection for longitudinal ordinal and count data in Nikoloulopoulos, Joe and Chaganty (2011) <doi:10.1093/biostatistics/kxr005>, Nikoloulopoulos (2016) <doi:10.1002/sim.6871> and Nikoloulopoulos (2017) <arXiv:1510.07376>.

Inferences about counterfactuals are essential for prediction, answering what if questions, and estimating causal effects. However, when the counterfactuals posed are too far from the data at hand, conclusions drawn from well-specified statistical analyses become based largely on speculation hidden in convenient modeling assumptions that few would be willing to defend. Unfortunately, standard statistical approaches assume the veracity of the model rather than revealing the degree of model-dependence, which makes this problem hard to detect. WhatIf offers easy-to-apply methods to evaluate counterfactuals that do not require sensitivity testing over specified classes of models. If an analysis fails the tests offered here, then we know that substantive inferences will be sensitive to at least some modeling choices that are not based on empirical evidence, no matter what method of inference one chooses to use. WhatIf implements the methods for evaluating counterfactuals discussed in Gary King and Langche Zeng, 2006, "The Dangers of Extreme Counterfactuals," Political Analysis 14 (2) <DOI:10.1093/pan/mpj004>; and Gary King and Langche Zeng, 2007, "When Can History Be Our Guide? The Pitfalls of Counterfactual Inference," International Studies Quarterly 51 (March) <DOI:10.1111/j.1468-2478.2007.00445.x>.

This package implements inferential and graphic procedures for the semiparametric proportional means regression of weighted composite endpoint of recurrent event and death (Mao and Lin, 2016, <doi:10.1093/biostatistics/kxv050>).

Opinionated functions that enable easier and faster analysis of Viva Insights data. There are three main types of functions in wpa': (i) Standard functions create a ggplot visual or a summary table based on a specific Viva Insights metric; (2) Report Generation functions generate HTML reports on a specific analysis area, e.g. Collaboration; (3) Other miscellaneous functions cover more specific applications (e.g. Subject Line text mining) of Viva Insights data. This package adheres to tidyverse principles and works well with the pipe syntax. wpa is built with the beginner-to-intermediate R users in mind, and is optimised for simplicity.

This package provides data from the United Nation's World Population Prospects 2019.

Within-subject mediation analysis using structural equation modeling. Examine how changes in an outcome variable between two conditions are mediated through one or more variables. Supports within-subject mediation analysis using the lavaan package by Rosseel (2012) <doi:10.18637/jss.v048.i02>, and extends Monte Carlo confidence interval estimation to missing data scenarios using the semmcci package by Pesigan and Cheung (2023) <doi:10.3758/s13428-023-02114-4>.

This package provides a set of wrappers intended to check, read and download information from the Wikimedia sources. It is specifically created to work with names of celebrities, in which case their information and statistics can be downloaded. Additionally, it also builds links and snippets to use in combination with the function gallery() in netCoin package.

This package contains functions for computing and plotting discrete wavelet transforms (DWT) and maximal overlap discrete wavelet transforms (MODWT), as well as their inverses. Additionally, it contains functionality for computing and plotting wavelet transform filters that are used in the above decompositions as well as multiresolution analyses.

This package implements the whitening methods (ZCA, PCA, Cholesky, ZCA-cor, and PCA-cor) discussed in Kessy, Lewin, and Strimmer (2018) "Optimal whitening and decorrelation", <doi:10.1080/00031305.2016.1277159>, as well as the whitening approach to canonical correlation analysis allowing negative canonical correlations described in Jendoubi and Strimmer (2019) "A whitening approach to probabilistic canonical correlation analysis for omics data integration", <doi:10.1186/s12859-018-2572-9>. The package also offers functions to simulate random orthogonal matrices, compute (correlation) loadings and explained variation. It also contains four example data sets (extended UCI wine data, TCGA LUSC data, nutrimouse data, extended pitprops data).

This package provides functions for finding and pulling data from the Wisconsin Department of Natural Resources ArcGIS REST APIs <https://dnrmaps.wi.gov/arcgis/rest/services> and <https://dnrmaps.wi.gov/arcgis2/rest/services>.

Create reproducible and transparent research projects in R'. This package is based on the Workflow for Open Reproducible Code in Science (WORCS), a step-by-step procedure based on best practices for Open Science. It includes an RStudio project template, several convenience functions, and all dependencies required to make your project reproducible and transparent. WORCS is explained in the tutorial paper by Van Lissa, Brandmaier, Brinkman, Lamprecht, Struiksma, & Vreede (2021). <doi:10.3233/DS-210031>.

This is a set of minimization tools (maximum likelihood estimation and least square fitting) to solve examples in the Johan Gabrielsson and Dan Weiner's book "Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications" 5th ed. (ISBN:9198299107). Examples include linear and nonlinear compartmental model, turn-over model, single or multiple dosing bolus/infusion/oral models, allometry, toxicokinetics, reversible metabolism, in-vitro/in-vivo extrapolation, enterohepatic circulation, metabolite modeling, Emax model, inhibitory model, tolerance model, oscillating response model, enantiomer interaction model, effect compartment model, drug-drug interaction model, receptor occupancy model, and rebound phenomena model.

Wrap-around Time Series (WATS) plots for interrupted time series designs with seasonal patterns. Longitudinal trajectories are shown in both Cartesian and polar coordinates. In many scenarios, a WATS plot more clearly shows the existence and effect size of of an intervention. This package accompanies "Graphical Data Analysis on the Circle: Wrap-Around Time Series Plots for (Interrupted) Time Series Designs" by Rodgers, Beasley, & Schuelke (2014) <doi:10.1080/00273171.2014.946589>; see citation("Wats") for details.

An R frontend for the WhiteboxTools library, which is an advanced geospatial data analysis platform developed by Prof. John Lindsay at the University of Guelph's Geomorphometry and Hydrogeomatics Research Group. WhiteboxTools can be used to perform common geographical information systems (GIS) analysis operations, such as cost-distance analysis, distance buffering, and raster reclassification. Remote sensing and image processing tasks include image enhancement (e.g. panchromatic sharpening, contrast adjustments), image mosaicing, numerous filtering operations, simple classification (k-means), and common image transformations. WhiteboxTools also contains advanced tooling for spatial hydrological analysis (e.g. flow-accumulation, watershed delineation, stream network analysis, sink removal), terrain analysis (e.g. common terrain indices such as slope, curvatures, wetness index, hillshading; hypsometric analysis; multi-scale topographic position analysis), and LiDAR data processing. Suggested citation: Lindsay (2016) <doi:10.1016/j.cageo.2016.07.003>.

Computes Bayesian wavelet shrinkage credible intervals for nonparametric regression. The method uses cumulants to derive Bayesian credible intervals for wavelet regression estimates. The first four cumulants of the posterior distribution of the estimates are expressed in terms of the observed data and integer powers of the mother wavelet functions. These powers are closely approximated by linear combinations of wavelet scaling functions at an appropriate finer scale. Hence, a suitable modification of the discrete wavelet transform allows the posterior cumulants to be found efficiently for any data set. Johnson transformations then yield the credible intervals themselves. Barber, S., Nason, G.P. and Silverman, B.W. (2002) <doi:10.1111/1467-9868.00332>.

This package provides a set of functions to make tracking the hidden movements of the Jack player easier. By tracking every possible path Jack might have traveled from the point of the initial murder including special movement such as through alleyways and via carriages, the police can more accurately narrow the field of their search. Additionally, by tracking all possible hideouts from round to round, rounds 3 and 4 should have a vastly reduced field of search.

Construct a Canonical Variate Analysis Biplot via the Generalised Singular Value Decomposition, for cases when the number of samples is less than the number of variables. For more information on biplots, see Gower JC, Lubbe SG, Le Roux NJ (2011) <doi:10.1002/9780470973196> and for more information on the generalised singular value decomposition, see Edelman A, Wang Y (2020) <doi:10.1137/18M1234412>.

First, we provide functions to calculate the partial derivative of the first-passage time diffusion probability density function (PDF) and cumulative distribution function (CDF) with respect to the first-passage time t (only for PDF), the upper barrier a, the drift rate v, the relative starting point w, the non-decision time t0, the inter-trial variability of the drift rate sv, the inter-trial variability of the rel. starting point sw, and the inter-trial variability of the non-decision time st0. In addition the PDF and CDF themselves are also provided. Most calculations are done on the logarithmic scale to make it more stable. Since the PDF, CDF, and their derivatives are represented as infinite series, we give the user the option to control the approximation errors with the argument precision'. For the numerical integration we used the C library cubature by Johnson, S. G. (2005-2013) <https://github.com/stevengj/cubature>. Numerical integration is required whenever sv, sw, and/or st0 is not zero. Note that numerical integration reduces speed of the computation and the precision cannot be guaranteed anymore. Therefore, whenever numerical integration is used an estimate of the approximation error is provided in the output list. Note: The large number of contributors (ctb) is due to copying a lot of C/C++ code chunks from the GNU Scientific Library (GSL). Second, we provide methods to sample from the first-passage time distribution with or without user-defined truncation from above. The first method is a new adaptive rejection sampler building on the works of Gilks and Wild (1992; <doi:10.2307/2347565>) and Hartmann and Klauer (in press). The second method is a rejection sampler provided by Drugowitsch (2016; <doi:10.1038/srep20490>). The third method is an inverse transformation sampler. The fourth method is a "pseudo" adaptive rejection sampler that builds on the first method. For more details see the corresponding help files.