Evaluate inline or chunks of R code in template files and replace with their output modifying the resulting template.

Topological data analysis is a powerful tool for finding non-linear global structure in whole datasets. The main tool of topological data analysis is persistent homology, which computes a topological shape descriptor of a dataset called a persistence diagram. TDApplied provides useful and efficient methods for analyzing groups of persistence diagrams with machine learning and statistical inference, and these functions can also interface with other data science packages to form flexible and integrated topological data analysis pipelines.

Likelihood-based methods for model fitting and assessment, prediction and intervention analysis of count time series following generalized linear models are provided. Models with the identity and with the logarithmic link function are allowed. The conditional distribution can be Poisson or Negative Binomial.

Converts text into speech using various text-to-speech (TTS) engines and provides an unified interface for accessing their functionality. With this package, users can easily generate audio files of spoken words, phrases, or sentences from plain text data. The package supports multiple TTS engines, including Google's Cloud Text-to-Speech API', Amazon Polly', Microsoft's Cognitive Services Text to Speech REST API', the Speechify Text-to-Speech API', and a free TTS engine called Coqui TTS'.

This package provides Apache Spark style window aggregation for R dataframes and remote dbplyr tables via mutate in dplyr flavour.

This package provides a fast, interactive cross-platform, and easy to share WebGL'-based 3D brain viewer that visualizes FreeSurfer and/or AFNI/SUMA surfaces. The viewer widget can be either standalone or embedded into R-shiny applications. The standalone version only require a web browser with WebGL2 support (for example, Chrome', Firefox', Safari'), and can be inserted into any websites. The R-shiny support allows the 3D viewer to be dynamically generated from reactive user inputs. Please check the publication by Wang, Magnotti, Zhang, and Beauchamp (2023, <doi:10.1523/ENEURO.0328-23.2023>) for electrode localization. This viewer has been fully adopted by RAVE <https://openwetware.org/wiki/RAVE>, an interactive toolbox to analyze iEEG data by Magnotti, Wang, and Beauchamp (2020, <doi:10.1016/j.neuroimage.2020.117341>). Please check citation("threeBrain") for details.

This package provides a step-up test for genetic rare variants in a gene or in a pathway. The method determines an optimal grouping of rare variants analytically. The method has been described in Hoffmann TJ, Marini NJ, and Witte JS (2010) <doi:10.1371/journal.pone.0013584>.

Enables the acquisition of Korean financial market data, designed to integrate seamlessly with the tidyquant package.

This package provides a model for the growth of self-limiting populations using three, four, or five parameter functions, which have wide applications in a variety of fields. The dependent variable in a dynamical modeling could be the population size at time x, where x is the independent variable. In the analysis of quantitative polymerase chain reaction (qPCR), the dependent variable would be the fluorescence intensity and the independent variable the cycle number. This package then would calculate the TWW cycle threshold.

An integrated suite of tools for creating, maintaining, and reusing FAIR (Findable, Accessible, Interoperable, Reusable) theories. Designed to support transparent and collaborative theory development, the package enables users to formalize theories, track changes with version control, assess pre-empirical coherence, and derive testable hypotheses. Aligning with open science principles and workflows, theorytools facilitates the systematic improvement of theoretical frameworks and enhances their discoverability and usability.

The two-parameter Xgamma and Poisson Xgamma distributions are analyzed, covering standard distribution and regression functions, maximum likelihood estimation, quantile functions, probability density and mass functions, cumulative distribution functions, and random number generation. References include: "Sen, S., Chandra, N. and Maiti, S. S. (2018). On properties and applications of a two-parameter XGamma distribution. Journal of Statistical Theory and Applications, 17(4): 674--685. <doi:10.2991/jsta.2018.17.4.9>." "Wani, M. A., Ahmad, P. B., Para, B. A. and Elah, N. (2023). A new regression model for count data with applications to health care data. International Journal of Data Science and Analytics. <doi:10.1007/s41060-023-00453-1>.".

Generalization of the classification and regression tree (CART) model that partitions subjects into terminal nodes and tailors machine learning model to each terminal node.

This package provides a bioinformatics tool for the estimation of the tumor purity from sequencing data. It uses the set of putative clonal somatic single nucleotide variants within copy number neutral segments to call tumor cellularity.

This package implements the Maximum Likelihood estimator for baseline, placebo, and treatment groups (three-group) experiments with non-compliance proposed by Gerber, Green, Kaplan, and Kern (2010).

Data frame class for storing collective movement data (e.g. fish schools, ungulate herds, baboon troops) collected from GPS trackers or computer vision tracking software.

This package implements the sensitivity analysis framework of Palomba (2026) "Sensitivity Analysis in Population Shares" <https://filippopalomba.github.io/#jmp> for randomized experiments with attrition, counterfactuals in structural models, and recentered instrumental variables. Computes and plots sensitivity bounds together with their confidence intervals and robustness summary measures.

This package provides bindings to a C grammar for Tree-sitter, to be used alongside the treesitter package. Tree-sitter builds concrete syntax trees for source files and can efficiently update them or generate code like producing R C API wrappers from C functions, structs and global definitions from header files.

This package provides methods to unify the different ways of creating predictive models and their different predictive formats for classification and regression. It includes methods such as K-Nearest Neighbors Schliep, K. P. (2004) <doi:10.5282/ubm/epub.1769>, Decision Trees Leo Breiman, Jerome H. Friedman, Richard A. Olshen, Charles J. Stone (2017) <doi:10.1201/9781315139470>, ADA Boosting Esteban Alfaro, Matias Gamez, Noelia Garcà a (2013) <doi:10.18637/jss.v054.i02>, Extreme Gradient Boosting Chen & Guestrin (2016) <doi:10.1145/2939672.2939785>, Random Forest Breiman (2001) <doi:10.1023/A:1010933404324>, Neural Networks Venables, W. N., & Ripley, B. D. (2002) <ISBN:0-387-95457-0>, Support Vector Machines Bennett, K. P. & Campbell, C. (2000) <doi:10.1145/380995.380999>, Bayesian Methods Gelman, A., Carlin, J. B., Stern, H. S., & Rubin, D. B. (1995) <doi:10.1201/9780429258411>, Linear Discriminant Analysis Venables, W. N., & Ripley, B. D. (2002) <ISBN:0-387-95457-0>, Quadratic Discriminant Analysis Venables, W. N., & Ripley, B. D. (2002) <ISBN:0-387-95457-0>, Logistic Regression Dobson, A. J., & Barnett, A. G. (2018) <doi:10.1201/9781315182780> and Penalized Logistic Regression Friedman, J. H., Hastie, T., & Tibshirani, R. (2010) <doi:10.18637/jss.v033.i01>.

The ta-test is a modified two-sample or two-group t-test of Gosset (1908). In small samples with less than 15 replicates,the ta-test significantly reduces type I error rate but has almost the same power with the t-test and hence can greatly enhance reliability or reproducibility of discoveries in biology and medicine. The ta-test can test single null hypothesis or multiple null hypotheses without needing to correct p-values.

Density, distribution function, the quantile function, random generation function, and maximum likelihood estimation.

This package creates a table of descriptive statistics for factor and numeric columns in a data frame. Displays these by groups, if any. Highly customizable, with support for html and pdf provided by kableExtra'. Respects original column order, column labels, and factor level order. See ?tablet.data.frame and vignettes.

Several functions to allow comparisons of data across different geographies, in particular for Canadian census data from different censuses.

Render clinical submission tables, listings, and figures to RTF', LaTeX', Typst', HTML', PDF', and DOCX from pre-summarised data frames, with no external Java or SAS dependency. Features include decimal alignment via font metrics, multi-level column headers with passthrough leaves, predicate-targeted cell styling, footnotes, group-aware pagination, and figures that wrap a plot or image in the same page chrome as a table. Built for Clinical Data Interchange Standards Consortium (CDISC) Analysis Data Model (ADaM) workflows and regulatory submissions to agencies such as the Food and Drug Administration (FDA), European Medicines Agency (EMA), and Pharmaceuticals and Medical Devices Agency (PMDA).

Utilities for rapidly loading specified rows and/or columns of data from large tab-separated value (tsv) files (large: e.g. 1 GB file of 10000 x 10000 matrix). tsvio is an R wrapper to C code that creates an index file for the rows of the tsv file, and uses that index file to collect rows and/or columns from the tsv file without reading the whole file into memory.