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This package contains logic for cell-specific gene set scoring of single cell RNA sequencing data.
The biomarker data set by Vermeulen et al. (2009) <doi:10.1016/S1470-2045(09)70154-8> is provided. The data source, however, is by Ruijter et al. (2013) <doi:10.1016/j.ymeth.2012.08.011>. The original data set may be downloaded from <https://medischebiologie.nl/wp-content/uploads/2019/02/qpcrdatamethods.zip>. This data set is for a real-time quantitative polymerase chain reaction (PCR) experiment that comprises the raw fluorescence data of 24,576 amplification curves. This data set comprises 59 genes of interest and 5 reference genes. Each gene was assessed on 366 neuroblastoma complementary DNA (cDNA) samples and on 18 standard dilution series samples (10-fold 5-point dilution series x 3 replicates + no template controls (NTC) x 3 replicates).
This package provides a tool for calculating and drawing "variable trees". Variable trees display information about nested subsets of a data frame. <doi:10.18637/jss.v114.i04>.
Generate Venn plots, summary tables, and ellipse paths for polygon clipping. Provides direct access to subsets of interest and offers flexible customization of Venn diagrams. Summary tables are also available when Venn diagram visualization is not suitable.
The spectral characteristics of a bivariate series (Marginal Spectra, Coherency- and Phase-Spectrum) determine whether there is a strong presence of short-, medium-, or long-term fluctuations (components of certain frequencies in the spectral representation of the series) in each one of them. These are induced by strong peaks of the marginal spectra of each series at the corresponding frequencies. The spectral characteristics also determine how strongly these short-, medium-, or long-term fluctuations of the two series are correlated between the two series. Information on this is provided by the Coherency spectrum at the corresponding frequencies. Finally, certain fluctuations of the two series may be lagged to each other. Information on this is provided by the Phase spectrum at the corresponding frequencies. The idea in this package is to define a VAR (Vector autoregression) model with desired spectral characteristics by specifying a number of polynomials, required to define the VAR. See Ioannidis(2007) <doi:10.1016/j.jspi.2005.12.013>. These are specified via their roots, instead of via their coefficients. This is an idea borrowed from the Time Series Library of R. Dahlhaus, where it is used for defining ARMA models for univariate time series. This way, one may e.g. specify a VAR inducing a strong presence of long-term fluctuations in series 1 and in series 2, which are weakly correlated, but lagged by a number of time units to each other, while short-term fluctuations in series 1 and in series 2, are strongly present only in one of the two series, while they are strongly correlated to each other between the two series. Simulation from such models allows studying the behavior of data-analysis tools, such as estimation of the spectra, under different circumstances, as e.g. peaks in the spectra, generating bias, induced by leakage.
Procedures for the manipulation, normalization, and plotting of phonetic and sociophonetic vowel formant data. vowels is the backend for the NORM website.
Extending the functionalities of the VGAM package with additional functions and datasets. At present, VGAMextra comprises new family functions (ffs) to estimate several time series models by maximum likelihood using Fisher scoring, unlike popular packages in CRAN relying on optim(), including ARMA-GARCH-like models, the Order-(p, d, q) ARIMAX model (non- seasonal), the Order-(p) VAR model, error correction models for cointegrated time series, and ARMA-structures with Student-t errors. For independent data, new ffs to estimate the inverse- Weibull, the inverse-gamma, the generalized beta of the second kind and the general multivariate normal distributions are available. In addition, VGAMextra incorporates new VGLM-links for the mean-function, and the quantile-function (as an alternative to ordinary quantile modelling) of several 1-parameter distributions, that are compatible with the class of VGLM/VGAM family functions. Currently, only fixed-effects models are implemented. All functions are subject to change; see the NEWS for further details on the latest changes.
Full model selection (detection of the relevant features and estimation of the number of clusters) for model-based clustering (see reference here <doi:10.1007/s11222-016-9670-1>). Data to analyze can be continuous, categorical, integer or mixed. Moreover, missing values can occur and do not necessitate any pre-processing. Shiny application permits an easy interpretation of the results.
Data version management on the file system for smaller projects. Manage data pipeline outputs with symbolic folder links, structured logging and reports, using R6 classes for encapsulation and data.table for speed. Directory-specific logs used as source of truth to allow portability of versioned data folders.
This package provides tools to estimate the impact of vaccination campaigns at population level (number of events averted, number of avertable events, number needed to vaccinate). Inspired by the methodology proposed by Foppa et al. (2015) <doi:10.1016/j.vaccine.2015.02.042> and Machado et al. (2019) <doi:10.2807/1560-7917.ES.2019.24.45.1900268> for influenza vaccination impact.
This package provides a robust and reproducible pipeline for extracting, cleaning, and analyzing athlete performance data generated by VALD ForceDecks systems. The package supports batch-oriented data processing for large datasets, standardized data transformation workflows, and visualization utilities for sports science research and performance monitoring. It is designed to facilitate reproducible analysis across multiple sports with comprehensive documentation and error handling.
Facilitates use and analysis of data about the armed conflict in Colombia resulting from the joint project between La Jurisdicción Especial para la Paz (JEP), La Comisión para el Esclarecimiento de la Verdad, la Convivencia y la No repetición (CEV), and the Human Rights Data Analysis Group (HRDAG). The data are 100 replicates from a multiple imputation through chained equations as described in Van Buuren and Groothuis-Oudshoorn (2011) <doi:10.18637/jss.v045.i03>. With the replicates the user can examine four human rights violations that occurred in the Colombian conflict accounting for the impact of missing fields and fully missing observations.
This package provides a user-friendly R shiny app for performing various statistical tests on datasets. It allows users to upload data in numerous formats and perform statistical analyses. The app dynamically adapts its options based on the selected columns and supports both single and multiple column comparisons. The app's user interface is designed to streamline the process of selecting datasets, columns, and test options, making it easy for users to explore and interpret their data. The underlying functions for statistical tests are well-organized and can be used independently within other R scripts.
Craft polished tables and plots in Markdown reports. Simply choose whether to treat your data as counts or metrics, and the package will automatically generate well-designed default tables and plots for you. Boiled down to the basics, with labeling features and simple interactive reports. All functions are tidyverse compatible.
Generation of domain variables, linearization of several non-linear population statistics (the ratio of two totals, weighted income percentile, relative median income ratio, at-risk-of-poverty rate, at-risk-of-poverty threshold, Gini coefficient, gender pay gap, the aggregate replacement ratio, the relative median income ratio, median income below at-risk-of-poverty gap, income quintile share ratio, relative median at-risk-of-poverty gap), computation of regression residuals in case of weight calibration, variance estimation of sample surveys by the ultimate cluster method (Hansen, Hurwitz and Madow, Sample Survey Methods And Theory, vol. I: Methods and Applications; vol. II: Theory. 1953, New York: John Wiley and Sons), variance estimation for longitudinal, cross-sectional measures and measures of change for single and multistage stage cluster sampling designs (Berger, Y. G., 2015, <doi:10.1111/rssa.12116>). Several other precision measures are derived - standard error, the coefficient of variation, the margin of error, confidence interval, design effect.
An implementation of Vasicek and Song goodness-of-fit tests. Several functions are provided to estimate differential Shannon entropy, i.e., estimate Shannon entropy of real random variables with density, and test the goodness-of-fit of some family of distributions, including uniform, Gaussian, log-normal, exponential, gamma, Weibull, Pareto, Fisher, Laplace and beta distributions; see Lequesne and Regnault (2020) <doi:10.18637/jss.v096.c01>.
This package implements D-vine quantile regression models with parametric or nonparametric pair-copulas. See Kraus and Czado (2017) <doi:10.1016/j.csda.2016.12.009> and Schallhorn et al. (2017) <doi:10.48550/arXiv.1705.08310>.
This package provides an interface to the VK API <https://vk.com/dev/methods>. VK <https://vk.com/> is the largest European online social networking service, based in Russia.
Create adjacency matrices of vocalisation graphs from dataframes containing sequences of speech and silence intervals, transforming these matrices into Markov diagrams, and generating datasets for classification of these diagrams by flattening them and adding global properties (functionals) etc. Vocalisation diagrams date back to early work in psychiatry (Jaffe and Feldstein, 1970) and social psychology (Dabbs and Ruback, 1987) but have only recently been employed as a data representation method for machine learning tasks including meeting segmentation (Luz, 2012) <doi:10.1145/2328967.2328970> and classification (Luz, 2013) <doi:10.1145/2522848.2533788>.
This package provides a tool for fast, efficient bitwise operations along the elements within a vector. Provides such functionality for AND, OR and XOR, as well as infix operators for all of the binary bitwise operations.
Fit and simulate latent position and cluster models for network data, using a fast Variational Bayes approximation developed in Salter-Townshend and Murphy (2013) <doi:10.1016/j.csda.2012.08.004>.
Turn R analysis outputs into full sentences, by writing vectors into in-sentence lists, pluralising words conditionally, spelling out numbers if they are at the start of sentences, writing out dates in full following US or UK style, and managing capitalisations in tidy data.
Facilitate the analysis of inter-limb and intra-limb coordination in human movement. It provides functions for calculating the phase angle between two segments, enabling researchers and practitioners to quantify the coordination patterns within and between limbs during various motor tasks. Needham, R., Naemi, R., & Chockalingam, N. (2014) <doi:10.1016/j.jbiomech.2013.12.032>. Needham, R., Naemi, R., & Chockalingam, N. (2015) <doi:10.1016/j.jbiomech.2015.07.023>. Tepavac, D., & Field-Fote, E. C. (2001) <doi:10.1123/jab.17.3.259>. Park, J.H., Lee, H., Cho, Js. et al. (2021) <doi:10.1038/s41598-020-80237-w>.
Estimating the disparity between two groups based on the extended model of the Peters-Belson (PB) method. Our model is the first work on the longitudinal data, and also can set a varying variable to find the complicated association between other variables and the varying variable. Our work is an extension of the Peters-Belson method which was originally published in Peters (1941)<doi:10.1080/00220671.1941.10881036> and Belson (1956)<doi:10.2307/2985420>.