This package contains all of the functions necessary for the complete analysis of a continuous glucose monitoring study and can be applied to data measured by various existing CGM devices such as FreeStyle Libre', Glutalor', Dexcom and Medtronic CGM'. It reads a series of data files, is able to convert various formats of time stamps, can deal with missing values, calculates both regular statistics and nonlinear statistics, and conducts group comparison. It also displays results in a concise format. Also contains two unique features new to CGM analysis: one is the implementation of strictly standard mean difference and the class of effect size; the other is the development of a new type of plot called antenna plot. It corresponds to Zhang XD'(2018)<doi:10.1093/bioinformatics/btx826>'s article CGManalyzer: an R package for analyzing continuous glucose monitoring studies'.

This package provides equations commonly used in clinical pharmacokinetics and clinical pharmacology, such as equations for dose individualization, compartmental pharmacokinetics, drug exposure, anthropomorphic calculations, clinical chemistry, and conversion of common clinical parameters. Where possible and relevant, it provides multiple published and peer-reviewed equations within the respective R function.

Encrypts and decrypts using basic ciphers. None of these should be used in place of real encryption using state of the art tools. The ciphers included use methods described in the ciphers's Wikipedia and cryptography hobby websites.

This package provides a chess program which allows the user to create a game, add moves, check for legal moves and game result, plot the board, take back, read and write FEN (Forsythâ Edwards Notation). A basic chess engine based on minimax is implemented.

Takes the outputs of a caret confusion matrix and allows for the quick conversion of these list items to lists. The intended usage is to allow the tool to work with the outputs of machine learning classification models. This tool works with classification problems for binary and multi-classification problems and allows for the record level conversion of the confusion matrix outputs. This is useful, as it allows quick conversion of these objects for storage in database systems and to track ML model performance over time. Traditionally, this approach has been used for highlighting model representation and feature slippage.

This package provides tools to simulate categorical raster data, including objects from the terra package. Functions focus on generating edge pixel values from reclassified raster data derived from the United States Department of Agriculture (USDA) Cropland Data Layer products.

Calculation of various common and less common comfort indices such as predicted mean vote or the two node model. Converts physical variables such as relative to absolute humidity and evaluates the performance of comfort indices.

Stacking rings are tools used to stack pottery in a Kiln. A relatively large group of stacking rings was found in the area of the sanctuary of Dionysos in Miletus in the 1970s. Measurements and additional info is gathered in this package and made available for use by other researchers. The data along with its archaeological context and analysis has been published in "Archäologischer Anzeiger" (2020/1, <doi:10.34780/aa.v0i1.1014>).

The Concordance Test is a non-parametric method for testing whether two o more samples originate from the same distribution. It extends the Kendall Tau correlation coefficient when there are only two groups. For details, see Alcaraz J., Anton-Sanchez L., Monge J.F. (2022) The Concordance Test, an Alternative to Kruskal-Wallis Based on the Kendall-tau Distance: An R Package. The R Journal 14, 26â 53 <doi:10.32614/RJ-2022-039>.

Simulating bivariate survival data from various copula models. Estimating bivariate copula models with semiparametric or Weibull margins under various copulas. Two different ways to estimate the association parameter in copula models are implemented. A goodness-of-fit test for the Gumbel and Clayton copulas is also implemented for semiparametric models. See Emura, Lin and Wang (2010) <doi:10.1016/j.csda.2010.03.013> for details.

Simulate plasma caffeine concentrations using population pharmacokinetic model described in Lee, Kim, Perera, McLachlan and Bae (2015) <doi:10.1007/s00431-015-2581-x>.

Cure dependent censoring regression models for long-term survival multivariate data. These models are based on extensions of the frailty models, capable to accommodating the cure fraction and the dependence between failure and censoring times, with Weibull and piecewise exponential marginal distributions. Theoretical details regarding the models implemented in the package can be found in Schneider et al. (2022) <doi:10.1007/s10651-022-00549-0>.

To optimize clinical trial designs and data analysis methods consistently through trial simulation, we need to simulate multivariate mixed-type virtual patient data independent of designs and analysis methods under evaluation. To make the outcome of optimization more realistic, relevant empirical patient level data should be utilized when itâ s available. However, a few problems arise in simulating trials based on small empirical data, where the underlying marginal distributions and their dependence structure cannot be understood or verified thoroughly due to the limited sample size. To resolve this issue, we use the copula invariance property, which can generate the joint distribution without making a strong parametric assumption. The function copula.sim can generate virtual patient data with optional data validation methods that are based on energy distance and ball divergence measurement. The function compare.copula.sim can conduct comparison of marginal mean and covariance of simulated data. To simulate patient-level data from a hypothetical treatment arm that would perform differently from the observed data, the function new.arm.copula.sim can be used to generate new multivariate data with the same dependence structure of the original data but with a shifted mean vector.

This package provides some simple functions for printing text in color in markdown or Quarto documents, to be rendered as HTML or LaTeX. This is useful when writing about the use of colors in graphs or tables, where you want to print their names in their actual color to give a direct impression of the color, like â redâ shown in red, or â blueâ shown in blue.

Puzzle game that can be played in the R console. Help the alien to find the ship.

Utilizes spatial association marginal contributions derived from spatial stratified heterogeneity to capture the degree of correlation between spatial patterns.

Function using lemmatization to classify educational programs according to the CINE(Classification International Normalized of Education) for Peru.

This package implements the board game CamelUp for use in introductory statistics classes using a Shiny app.

This package provides the ability to create interaction maps, discover CNV map domains (edges), gene annotate interactions, and create interactive visualizations of these CNV interaction maps.

Estimation of crop water demand can be processed via this package. As example, the data from TerraClimate dataset (<https://www.climatologylab.org/terraclimate.html>) calibrated with automatic weather stations of National Meteorological Institute of Brazil is available in a coarse spatial resolution to do the crop water demand. However, the user have also the option to download the variables directly from TerraClimate repository with the download.terraclimate function and access the original TerraClimate products. If the user believes that is necessary calibrate the variables, there is another function to do it. Lastly, the estimation of the crop water demand present in this package can be run for all the Brazilian territory with TerraClimate dataset.

Fit multiclass Classification version of Bayesian Adaptive Smoothing Splines (CBASS) to data using reversible jump MCMC. The multiclass classification problem consists of a response variable that takes on unordered categorical values with at least three levels, and a set of inputs for each response variable. The CBASS model consists of a latent multivariate probit formulation, and the means of the latent Gaussian random variables are specified using adaptive regression splines. The MCMC alternates updates of the latent Gaussian variables and the spline parameters. All the spline parameters (variables, signs, knots, number of interactions), including the number of basis functions used to model each latent mean, are inferred. Functions are provided to process inputs, initialize the chain, run the chain, and make predictions. Predictions are made on a probabilistic basis, where, for a given input, the probabilities of each categorical value are produced. See Marrs and Francom (2023) "Multiclass classification using Bayesian multivariate adaptive regression splines" Under review.

Extension of cmprsk to Stratified and Clustered data. A goodness of fit test for Fine-Gray model is also provided. Methods are detailed in the following articles: Zhou et al. (2011) <doi:10.1111/j.1541-0420.2010.01493.x>, Zhou et al. (2012) <doi:10.1093/biostatistics/kxr032>, Zhou et al. (2013) <doi: 10.1002/sim.5815>.

This package provides functions for loading large (10M+ lines) CSV and other delimited files, similar to read.csv, but typically faster and using less memory than the standard R loader. While not entirely general, it covers many common use cases when the types of columns in the CSV file are known in advance. In addition, the package provides a class int64', which represents 64-bit integers exactly when reading from a file. The latter is useful when working with 64-bit integer identifiers exported from databases. The CSV file loader supports common column types including integer', double', string', and int64', leaving further type transformations to the user.

Evaluates the stability and significance of clusters on igraph graphs. Supports weighted and unweighted graphs. Implements the cluster evaluation methods defined by Arratia A, Renedo M (2021) <doi:10.7717/peerj-cs.600>. Also includes an implementation of the Reduced Mutual Information introduced by Newman et al. (2020) <doi:10.1103/PhysRevE.101.042304>.