Causal inference for a binary treatment and continuous outcome using Bayesian Causal Forests. See Hahn, Murray and Carvalho (2020) <doi:10.1214/19-BA1195> for additional information. This implementation relies on code originally accompanying Pratola et. al. (2013) <arXiv:1309.1906>.

This package provides methods for choosing the rank of an SVD (singular value decomposition) approximation via cross validation. The package provides both Gabriel-style "block" holdouts and Wold-style "speckled" holdouts. It also includes an implementation of the SVDImpute algorithm. For more information about Bi-cross-validation, see Owen & Perry's 2009 AoAS article (at <arXiv:0908.2062>) and Perry's 2009 PhD thesis (at <arXiv:0909.3052>).

Applies Beta Control Charts to defined values. The Beta Chart presents control limits based on the Beta probability distribution, making it suitable for monitoring fraction data from a Binomial distribution as a replacement for p-Charts. The Beta Chart has been applied in three real studies and compared with control limits from three different schemes. The comparative analysis showed that: (i) the Beta approximation to the Binomial distribution is more appropriate for values confined within the [0, 1] interval; and (ii) the proposed charts are more sensitive to the average run length (ARL) in both in-control and out-of-control process monitoring. Overall, the Beta Charts outperform the Shewhart control charts in monitoring fraction data. For more details, see à ngelo Márcio Oliveira Santâ Anna and Carla Schwengber ten Caten (2012) <doi:10.1016/j.eswa.2012.02.146>.

An implementation of a collection of tools for exact Bayesian inference with discrete times series. This package contains functions that can be used for prediction, model selection, estimation, segmentation/change-point detection and other statistical tasks. Specifically, the functions provided can be used for the exact computation of the prior predictive likelihood of the data, for the identification of the a posteriori most likely (MAP) variable-memory Markov models, for calculating the exact posterior probabilities and the AIC and BIC scores of these models, for prediction with respect to log-loss and 0-1 loss and segmentation/change-point detection. Example data sets from finance, genetics, animal communication and meteorology are also provided. Detailed descriptions of the underlying theory and algorithms can be found in [Kontoyiannis et al. Bayesian Context Trees: Modelling and exact inference for discrete time series. Journal of the Royal Statistical Society: Series B (Statistical Methodology), April 2022. Available at: <arXiv:2007.14900> [stat.ME], July 2020] and [Lungu et al. Change-point Detection and Segmentation of Discrete Data using Bayesian Context Trees <arXiv:2203.04341> [stat.ME], March 2022].

This package provides a Bayesian model averaging approach to causal effect estimation based on the BCEE algorithm. Currently supports binary or continuous exposures and outcomes. For more details, see Talbot et al. (2015) <doi:10.1515/jci-2014-0035> Talbot and Beaudoin (2022) <doi:10.1515/jci-2021-0023>.

This package implements a wide variety of one- and two-parameter Bayesian CRM designs. The program can run interactively, allowing the user to enter outcomes after each cohort has been recruited, or via simulation to assess operating characteristics. See Sweeting et al. (2013): <doi:10.18637/jss.v054.i13>.

This package provides functions provide risk projections of invasive breast cancer based on Gail model according to National Cancer Institute's Breast Cancer Risk Assessment Tool algorithm for specified race/ethnic groups and age intervals. Gail MH, Brinton LA, et al (1989) <doi:10.1093/jnci/81.24.1879>. Marthew PB, Gail MH, et al (2016) <doi:10.1093/jnci/djw215>.

This package produces an economic evaluation of a sample of suitable variables of cost and effectiveness / utility for two or more interventions, e.g. from a Bayesian model in the form of MCMC simulations. This package computes the most cost-effective alternative and produces graphical summaries and probabilistic sensitivity analysis, see Baio et al (2017) <doi:10.1007/978-3-319-55718-2>.

Developed for the following tasks. Simulating, computing maximum likelihood estimator, computing the Fisher information matrix, computing goodness-of-fit measures, and correcting bias of the ML estimator for a wide range of distributions fitted to units placed on progressive type-I interval censoring and progressive type-II censoring plans. The methods of Cox and Snell (1968) <doi:10.1111/j.2517-6161.1968.tb00724.x> and bootstrap method for computing the bias-corrected maximum likelihood estimator.

Users can estimate the treatment effect for multiple subgroups basket trials based on the Bayesian Cluster Hierarchical Model (BCHM). In this model, a Bayesian non-parametric method is applied to dynamically calculate the number of clusters by conducting the multiple cluster classification based on subgroup outcomes. Hierarchical model is used to compute the posterior probability of treatment effect with the borrowing strength determined by the Bayesian non-parametric clustering and the similarities between subgroups. To use this package, JAGS software and rjags package are required, and users need to pre-install them.

The Behavioral Change Point Analysis (BCPA) is a method of identifying hidden shifts in the underlying parameters of a time series, developed specifically to be applied to animal movement data which is irregularly sampled. The method is based on: E. Gurarie, R. Andrews and K. Laidre A novel method for identifying behavioural changes in animal movement data (2009) Ecology Letters 12:5 395-408. A development version is on <https://github.com/EliGurarie/bcpa>. NOTE: the BCPA method may be useful for any univariate, irregularly sampled Gaussian time-series, but animal movement analysts are encouraged to apply correlated velocity change point analysis as implemented in the smoove package, as of this writing on GitHub at <https://github.com/EliGurarie/smoove>. An example of a univariate analysis is provided in the UnivariateBCPA vignette.

This package provides bias-corrected estimates for the regression coefficients of a marginal model estimated with generalized estimating equations. Details about the bias formula used are in Lunardon, N., Scharfstein, D. (2017) <doi:10.1002/sim.7366>.

This package provides a collection of functions for structure learning of causal networks and estimation of joint causal effects from observational Gaussian data. Main algorithm consists of a Markov chain Monte Carlo scheme for posterior inference of causal structures, parameters and causal effects between variables. References: F. Castelletti and A. Mascaro (2021) <doi:10.1007/s10260-021-00579-1>, F. Castelletti and A. Mascaro (2022) <doi:10.48550/arXiv.2201.12003>.

This Rcpp-based package implements a highly efficient data structure and algorithm for performing alignment of short reads from CRISPR or shRNA screens to reference barcode library. Sequencing error are considered and matching qualities are evaluated based on Phred scores. A Bayes classifier is employed to predict the originating barcode of a read. The package supports provision of user-defined probability models for evaluating matching qualities. The package also supports multi-threading.

Gene expression profiles are commonly utilized to infer disease subtypes and many clustering methods can be adopted for this task. However, existing clustering methods may not perform well when genes are highly correlated and many uninformative genes are included for clustering. To deal with these challenges, we develop a novel clustering method in the Bayesian setting. This method, called BCSub, adopts an innovative semiparametric Bayesian factor analysis model to reduce the dimension of the data to a few factor scores for clustering. Specifically, the factor scores are assumed to follow the Dirichlet process mixture model in order to induce clustering.

Bindings to the blowfish password hashing algorithm <https://www.openbsd.org/papers/bcrypt-paper.pdf> derived from the OpenBSD implementation.

BCFtools is a set of utilities that manipulate variant calls in the Variant Call Format (VCF) and its binary counterpart BCF. All commands work transparently with both VCFs and BCFs, both uncompressed and BGZF-compressed.

Implementation of the BC3NET algorithm for gene regulatory network inference (de Matos Simoes and Frank Emmert-Streib, Bagging Statistical Network Inference from Large-Scale Gene Expression Data, PLoS ONE 7(3): e33624, <doi:10.1371/journal.pone.0033624>).

Search, query, and download tabular and geospatial data from the British Columbia Data Catalogue (<https://catalogue.data.gov.bc.ca/>). Search catalogue data records based on keywords, data licence, sector, data format, and B.C. government organization. View metadata directly in R, download many data formats, and query geospatial data available via the B.C. government Web Feature Service ('WFS') using dplyr syntax.

Diagnostic tools based on two-way anova and median-polish residual plots for Bicluster output obtained from packages; "biclust" by Kaiser et al.(2008),"isa2" by Csardi et al. (2010) and "fabia" by Hochreiter et al. (2010). Moreover, It provides visualization tools for bicluster output and corresponding non-bicluster rows- or columns outcomes. It has also extended the idea of Kaiser et al.(2008) which is, extracting bicluster output in a text format, by adding two bicluster methods from the fabia and isa2 R packages.

Various layers of B.C., including administrative boundaries, natural resource management boundaries, census boundaries etc. All layers are available in BC Albers (<https://spatialreference.org/ref/epsg/3005/>) equal-area projection, which is the B.C. government standard. The layers are sourced from the British Columbia and Canadian government under open licenses, including B.C. Data Catalogue (<https://data.gov.bc.ca>), the Government of Canada Open Data Portal (<https://open.canada.ca/en/using-open-data>), and Statistics Canada (<https://www.statcan.gc.ca/en/reference/licence>).

Implementing the Block Coordinate Ascent with One-Step Generalized Rosen (BCA1SG) algorithm on the semiparametric models for panel count data, interval-censored survival data, and degradation data. A comprehensive description of the BCA1SG algorithm can be found in Wang et al. (2020) <https://github.com/yudongstat/BCA1SG/blob/master/BCA1SG.pdf>. For details of the semiparametric models for panel count data, interval-censored survival data, and degradation data, please see Wellner and Zhang (2007) <doi:10.1214/009053607000000181>, Huang and Wellner (1997) <ISBN:978-0-387-94992-5>, and Wang and Xu (2010) <doi:10.1198/TECH.2009.08197>, respectively.

Fully Bayesian Classification with a subset of high-dimensional features, such as expression levels of genes. The data are modeled with a hierarchical Bayesian models using heavy-tailed t distributions as priors. When a large number of features are available, one may like to select only a subset of features to use, typically those features strongly correlated with the response in training cases. Such a feature selection procedure is however invalid since the relationship between the response and the features has be exaggerated by feature selection. This package provides a way to avoid this bias and yield better-calibrated predictions for future cases when one uses F-statistic to select features.

bcl2fastq is conversion software, which can be used to both demultiplex data and convert BCL files to FASTQ files.