Analysis of multivariate data with two-way completely randomized factorial design. The analysis is based on fully nonparametric, rank-based methods and uses test statistics based on the Dempster's ANOVA, Wilk's Lambda, Lawley-Hotelling and Bartlett-Nanda-Pillai criteria. The multivariate response is allowed to be ordinal, quantitative, binary or a mixture of the different variable types. The package offers two functions performing the analysis, one for small and the other for large sample sizes. The underlying methodology is largely described in Bathke and Harrar (2016) <doi:10.1007/978-3-319-39065-9_7> and in Munzel and Brunner (2000) <doi:10.1016/S0378-3758(99)00212-8> and in Kiefel and Bathke (2022) <doi:10.1515/stat-2022-0112>.

Nonparametric Tests for Main Effects, Simple Effects and Interaction Effect with Censored Data and Two Factorial Influencing Variables.

This package provides a nested menu widget for usage in Shiny applications. This is useful for hierarchical choices (e.g. continent, country, city).

This data package contains the Item Response Theory (IRT) parameters for the National Center for Education Statistics (NCES) items used on the National Assessment of Education Progress (NAEP) from 1990 to 2015. The values in these tables are used along with NAEP data to turn student item responses into scores and include information about item difficulty, discrimination, and guessing parameter for 3 parameter logit (3PL) items. Parameters for Generalized Partial Credit Model (GPCM) items are also included. The adjustments table contains the information regarding the treatment of items (e.g., deletion of an item or a collapsing of response categories), when these items did not appear to fit the item response models used to describe the NAEP data. Transformation constants change the score estimates that are obtained from the IRT scaling program to the NAEP reporting metric. Values from the years 2000 - 2013 were taken from the NCES website <https://nces.ed.gov/nationsreportcard/> and values from 1990 - 1998 and 2015 were extracted from their NAEP data files. All subtest names were reduced and homogenized to one word (e.g. "Reading to gain information" became "information"). The various subtest names for univariate transformation constants were all homogenized to "univariate".

This package provides functions for revealing what happens when effect size estimates from previous studies are taken into account when evaluating each new dataset in a study sequence. The analyses can be conducted for cumulative meta-analyses and for Bayesian data analyses. The package contains sample data for a wide selection of research topics. Jointly considering previous findings along with new data is more likely to result in correct conclusions than does the traditional practice of not incorporating previous findings, which often results in a back and forth ping-pong of conclusions when evaluating a sequence of studies. O'Connor & Ermacora (2021, <doi:10.1037/cbs0000259>).

Th-U-Pb electron microprobe age dating of monazite, as originally described in <doi:10.1016/0009-2541(96)00024-1>.

Clustering unilayer and multilayer network data by means of finite mixtures is the main utility of netClust.

Spatial (cross-)covariance and related geostatistical tools: the nonparametric (cross-)covariance function , the spline correlogram, the nonparametric phase coherence function, local indicators of spatial association (LISA), (Mantel) correlogram, (Partial) Mantel test.

This package provides a toolkit for medical records data analysis. The naryn package implements an efficient data structure for storing medical records, and provides a set of functions for data extraction, manipulation and analysis.

This comprehensive toolkit provide a consistent and extensible framework for working with missing values in vectors. The companion package tidyimpute provides similar functionality for list-like and table-like structures). Functions exist for detection, removal, replacement, imputation, recollection, etc. of NAs'.

Dealing with neutrosophic data of the form N=D+I(where N is a Neutrosophic number ,D is the determinant part of the number and I is the indeterminacy part) using the neutrosophic two way anova test keeps the type I error low. This algorithm calculates the fisher statistics when we have a neutrosophic data, also tests two hypothesizes, first is to test differences between treatments, and second is to test differences between sectors. For more information see Miari, Mahmoud; Anan, Mohamad Taher; Zeina, Mohamed Bisher(2022) <https://www.americaspg.com/articleinfo/21/show/1058>.

This package provides a finite-population significance test of the sharp causal null hypothesis that treatment exposure X has no effect on final outcome Y, within the principal stratum of Compliers. A generalized likelihood ratio test statistic is used, and the resulting p-value is exact. Currently, it is assumed that there are only Compliers and Never Takers in the population.

This package performs network-based source estimation. Different approaches are available: effective distance median, recursive backtracking, and centrality-based source estimation. Additionally, we provide public transportation network data as well as methods for data preparation, source estimation performance analysis and visualization.

Estimators and variance estimators tailored to the NILS hierarchical design (Adler et al. 2020, <https://res.slu.se/id/publ/105630>; Grafström et al. 2023, <https://res.slu.se/id/publ/128235>). The National Inventories of Landscapes in Sweden (NILS) is a long-term national monitoring program that collects, analyses and presents data on Swedish nature, covering both common and rare habitats <https://www.slu.se/om-slu/organisation/institutioner/skoglig-resurshushallning/miljoanalys/nils/>.

Imputation for both missing covariates and censored observations (optional) for survival data with missing covariates by the nearest neighbor based multiple imputation algorithm as described in Hsu et al. (2006) <doi:10.1002/sim.2452>, and Hsu and Yu (2018) <doi: 10.1177/0962280218772592>. Note that the current version can only impute for a situation with one missing covariate.

This package provides a Bayesian approach to estimate the number of occurred-but-not-yet-reported cases from incomplete, time-stamped reporting data for disease outbreaks. NobBS learns the reporting delay distribution and the time evolution of the epidemic curve to produce smoothed nowcasts in both stable and time-varying case reporting settings, as described in McGough et al. (2020) <doi:10.1371/journal.pcbi.1007735>.

This package provides tools for non-parametric Fourier deconvolution using the N-Power Fourier Deconvolution (NPFD) method. This package includes methods for density estimation (densprf()) and sample generation (createSample()), enabling users to perform statistical analyses on mixed or replicated data sets.

Statistical entropy analysis of network data as introduced by Frank and Shafie (2016) <doi:10.1177/0759106315615511>, and a in textbook which is in progress.

Design and analysis of flexible platform trials with non-concurrent controls. Functions for data generation, analysis, visualization and running simulation studies are provided. The implemented analysis methods are described in: Bofill Roig et al. (2022) <doi:10.1186/s12874-022-01683-w>, Saville et al. (2022) <doi:10.1177/17407745221112013> and Schmidli et al. (2014) <doi:10.1111/biom.12242>.

We developed an inference tool based on approximate Bayesian computation to decipher network data and assess the strength of the inferred links between network's actors. It is a new multi-level approximate Bayesian computation (ABC) approach. At the first level, the method captures the global properties of the network, such as a scale-free structure and clustering coefficients, whereas the second level is targeted to capture local properties, including the probability of each couple of genes being linked. Up to now, Approximate Bayesian Computation (ABC) algorithms have been scarcely used in that setting and, due to the computational overhead, their application was limited to a small number of genes. On the contrary, our algorithm was made to cope with that issue and has low computational cost. It can be used, for instance, for elucidating gene regulatory network, which is an important step towards understanding the normal cell physiology and complex pathological phenotype. Reverse-engineering consists in using gene expressions over time or over different experimental conditions to discover the structure of the gene network in a targeted cellular process. The fact that gene expression data are usually noisy, highly correlated, and have high dimensionality explains the need for specific statistical methods to reverse engineer the underlying network.

Infer system functioning with empirical NETwork COMparisons. These methods are part of a growing paradigm in network science that uses relative comparisons of networks to infer mechanistic classifications and predict systemic interventions. They have been developed and applied in Langendorf and Burgess (2021) <doi:10.1038/s41598-021-99251-7>, Langendorf (2020) <doi:10.1201/9781351190831-6>, and Langendorf and Goldberg (2019) <doi:10.48550/arXiv.1912.12551>.

Natural strata can be used in observational studies to balance the distributions of many covariates across any number of treatment groups and any number of comparisons. These strata have proportional amounts of units within each stratum across the treatments, allowing for simple interpretation and aggregation across strata. Within each stratum, the units are chosen using randomized rounding of a linear program that balances many covariates. For more details, see Brumberg et al. (2022) <doi:10.1111/rssa.12848> and Brumberg et al.(2023) <doi:10.1093/jrsssc/qlad010>. To solve the linear program, the Gurobi commercial optimization software is recommended, but not required. The gurobi R package can be installed by following the instructions at <https://docs.gurobi.com/projects/optimizer/en/current/reference/r/setup.html> after claiming your free academic license at <https://www.gurobi.com/academia/academic-program-and-licenses/>.

In shotgun proteomics, shared peptides (i.e., peptides that might originate from different proteins sharing homology, from different proteoforms due to alternative mRNA splicing, post-translational modifications, proteolytic cleavages, and/or allelic variants) represent a major source of ambiguity in protein identifications. The net4pg package allows to assess and handle ambiguity of protein identifications. It implements methods for two main applications. First, it allows to represent and quantify ambiguity of protein identifications by means of graph connected components (CCs). In graph theory, CCs are defined as the largest subgraphs in which any two vertices are connected to each other by a path and not connected to any other of the vertices in the supergraph. Here, proteins sharing one or more peptides are thus gathered in the same CC (multi-protein CC), while unambiguous protein identifications constitute CCs with a single protein vertex (single-protein CCs). Therefore, the proportion of single-protein CCs and the size of multi-protein CCs can be used to measure the level of ambiguity of protein identifications. The package implements a strategy to efficiently calculate graph connected components on large datasets and allows to visually inspect them. Secondly, the net4pg package allows to exploit the increasing availability of matched transcriptomic and proteomic datasets to reduce ambiguity of protein identifications. More precisely, it implement a transcriptome-based filtering strategy fundamentally consisting in the removal of those proteins whose corresponding transcript is not expressed in the sample-matched transcriptome. The underlying assumption is that, according to the central dogma of biology, there can be no proteins without the corresponding transcript. Most importantly, the package allows to visually inspect the effect of the filtering on protein identifications and quantify ambiguity before and after filtering by means of graph connected components. As such, it constitutes a reproducible and transparent method to exploit transcriptome information to enhance protein identifications. All methods implemented in the net4pg package are fully described in Fancello and Burger (2022) <doi:10.1186/s13059-022-02701-2>.

Geospatial data for creating maps of New South Wales (NSW), Australia, and some helpers to work with common problems like normalising postcodes. Registers its data with cartographer'.