Lightweight maps of mammals of the world. These maps are a comprehensive collection of maps aligned with the Mammal Diversity Database taxonomy of the American Society of Mammalogists. They are generated at low resolution for easy access, consultation and manipulation in shapefile format. The package connects to a binary backup hosted in the Digital Ocean cloud service and allows individual or batch download of any mammal species in the mdd taxonomy by providing the scientific species name.

Quantifies ecological memory in long time-series using Random Forest models ('Benito', Gil-Romera', and Birks 2019 <doi:10.1111/ecog.04772>) fitted with ranger (Wright and Ziegler 2017 <doi:10.18637/jss.v077.i01>). Ecological memory is assessed by modeling a response variable as a function of lagged predictors, distinguishing endogenous memory (lagged response) from exogenous memory (lagged environmental drivers). Designed for palaeoecological datasets and simulated pollen curves from virtualPollen', but applicable to any long time-series with environmental drivers and a biotic response.

Fit Gaussian Multinomial mixed-effects models for small area estimation: Model 1, with one random effect in each category of the response variable (Lopez-Vizcaino,E. et al., 2013) <doi:10.1177/1471082X13478873>; Model 2, introducing independent time effect; Model 3, introducing correlated time effect. mme calculates direct and parametric bootstrap MSE estimators (Lopez-Vizcaino,E et al., 2014) <doi:10.1111/rssa.12085>.

The routine gof_test() in this package runs the goodness-of-fit test using various test statistic for multivariate data. Models under the null hypothesis can either be simple or allow for parameter estimation. p values are found via the parametric bootstrap (simulation). The routine gof_test_adjusted_pvalues() runs several tests and then finds a p value adjusted for simultaneous inference. The routine gof_power() allows the estimation of the power of the tests. hybrid_test() and hybrid_power() do the same by first generating a Monte Carlo data set under the null hypothesis and then running a number of two-sample methods. The routine run.studies() allows a user to quickly study the power of a new method and how it compares to those included in the package via a large number of case studies. For details of the methods and references see the included vignettes.

This package provides a utility library to facilitate the generalization of statistical methods built on a regression framework. Package developers can use modelObj methods to initiate a regression analysis without concern for the details of the regression model and the method to be used to obtain parameter estimates. The specifics of the regression step are left to the user to define when calling the function. The user of a function developed within the modelObj framework creates as input a modelObj that contains the model and the R methods to be used to obtain parameter estimates and to obtain predictions. In this way, a user can easily go from linear to non-linear models within the same package.

Uses recursive partitioning to create homogeneous subgroups based on structural equation models fit in Mplus', a stand-alone program developed by Muthen and Muthen.

Imputation of incomplete continuous or categorical datasets; Missing values are imputed with a principal component analysis (PCA), a multiple correspondence analysis (MCA) model or a multiple factor analysis (MFA) model; Perform multiple imputation with and in PCA or MCA.

This package provides new data-structure support for multi-precision computing for R users. The package supports 16-bit, 32-bit, and 64-bit operations. To the best of our knowledge, MPCR differs from the currently available packages in the following: MPCR introduces a new data structure that supports three different precisions (16-bit, 32-bit, and 64-bit), allowing for optimized memory allocation based on the desired precision. This feature offers significant advantages in memory optimization. MPCR extends support to all basic linear algebra methods across different precisions. Optional GPU acceleration via CUDA is available for 32-bit and 64-bit operations when CUDA Toolkit is detected during installation, while 16-bit operations are GPU-only and limited to matrix-matrix multiplication. MPCR maintains a consistent interface with normal R functions, allowing for seamless code integration and a user-friendly experience.

This package implements a methodology for the design and analysis of dose-response studies that combines aspects of multiple comparison procedures and modeling approaches (Bretz, Pinheiro and Branson, 2005, Biometrics 61, 738-748, <doi: 10.1111/j.1541-0420.2005.00344.x>). The package provides tools for the analysis of dose finding trials as well as a variety of tools necessary to plan a trial to be conducted with the MCP-Mod methodology. Please note: The MCPMod package will not be further developed, all future development of the MCP-Mod methodology will be done in the DoseFinding R-package.

Implementation of Matched Wake Analysis (mwa) for studying causal relationships in spatiotemporal event data, introduced by Schutte and Donnay (2014) <doi:10.1016/j.polgeo.2014.03.001>.

This package provides a number of testthat tests that can be used to verify that tidy(), glance() and augment() methods meet consistent specifications. This allows methods for the same generic to be spread across multiple packages, since all of those packages can make the same guarantees to users about returned objects.

Density, distribution function, quantile function, and random generation function based on Salem, H. M. (2019)<doi:10.5539/mas.v13n2p54>. In addition, a numerical method for maximum likelihood estimation is provided.

This package implements Gibbs sampling and Bayes factors for multinomial models with linear inequality constraints on the vector of probability parameters. As special cases, the model class includes models that predict a linear order of binomial probabilities (e.g., p[1] < p[2] < p[3] < .50) and mixture models assuming that the parameter vector p must be inside the convex hull of a finite number of predicted patterns (i.e., vertices). A formal definition of inequality-constrained multinomial models and the implemented computational methods is provided in: Heck, D.W., & Davis-Stober, C.P. (2019). Multinomial models with linear inequality constraints: Overview and improvements of computational methods for Bayesian inference. Journal of Mathematical Psychology, 91, 70-87. <doi:10.1016/j.jmp.2019.03.004>. Inequality-constrained multinomial models have applications in the area of judgment and decision making to fit and test random utility models (Regenwetter, M., Dana, J., & Davis-Stober, C.P. (2011). Transitivity of preferences. Psychological Review, 118, 42â 56, <doi:10.1037/a0021150>) or to perform outcome-based strategy classification to select the decision strategy that provides the best account for a vector of observed choice frequencies (Heck, D.W., Hilbig, B.E., & Moshagen, M. (2017). From information processing to decisions: Formalizing and comparing probabilistic choice models. Cognitive Psychology, 96, 26â 40. <doi:10.1016/j.cogpsych.2017.05.003>).

This package provides a Comprehensive tool for almost all existing multiple testing methods for multiple families. The package summarizes the existing methods for multiple families multiple testing procedures (MTPs) such as double FDR, group Benjamini-Hochberg (GBH) procedure and average FDR controlling procedure. The package also provides some novel multiple testing procedures using selective inference idea.

This package performs meta-analysis and meta-regression using standard and robust methods with confidence intervals based on the profile likelihood. Robust methods are based on alternative distributions for the random effect, either the t-distribution (Lee and Thompson, 2008 <doi:10.1002/sim.2897> or Baker and Jackson, 2008 <doi:10.1007/s10729-007-9041-8>) or mixtures of normals (Beath, 2014 <doi:10.1002/jrsm.1114>).

Makes it possible to create an internally consistent repository consisting of selected packages from CRAN-like repositories. The user specifies a set of desired packages, and miniCRAN recursively reads the dependency tree for these packages, then downloads only this subset. The user can then install packages from this repository directly, rather than from CRAN. This is useful in production settings, e.g. server behind a firewall, or remote locations with slow (or zero) Internet access.

This package provides a mechanism to plot an interactive map using Mapbox GL (<https://docs.mapbox.com/mapbox-gl-js/api/>), a javascript library for interactive maps, and Deck.gl (<https://deck.gl/>), a javascript library which uses WebGL for visualising large data sets.

The rapid screening of effective and optimal therapies from large numbers of candidate combinations, as well as exploring subgroup efficacy, remains challenging, which necessitates innovative, integrated, and efficient trial designs(Yuan, Y., et al. (2016) <doi:10.1002/sim.6971>). MIDAS-2 package enables quick and continuous screening of promising combination strategies and exploration of their subgroup effects within a unified platform design framework. We used a regression model to characterize the efficacy pattern in subgroups. Information borrowing was applied through Bayesian hierarchical model to improve trial efficiency considering the limited sample size in subgroups(Cunanan, K. M., et al. (2019) <doi:10.1177/1740774518812779>). MIDAS-2 provides an adaptive drug screening and subgroup exploring framework to accelerate immunotherapy development in an efficient, accurate, and integrated fashion(Wathen, J. K., & Thall, P. F. (2017) <doi: 10.1177/1740774517692302>).

Procedures to simulate, estimate and diagnose MGARCH processes of BEKK and multivariate GJR (bivariate asymmetric GARCH model) specification.

This package provides global hypothesis tests, multiple testing procedures and simultaneous confidence intervals for multiple linear contrasts of regression coefficients in a single generalized estimating equation (GEE) model or across multiple GEE models. GEE models are fit by a modified version of the geeM package.

This package provides methods and models for analysing multigraphs as introduced by Shafie (2015) <doi:10.21307/joss-2019-011>, including methods to study local and global properties <doi:10.1080/0022250X.2016.1219732> and goodness of fit tests.

Check concordance of a vector of mutation impacts with standard dictionaries such as Sequence Ontology (SO) <http://www.sequenceontology.org/>, Mutation Annotation Format (MAF) <https://docs.gdc.cancer.gov/Encyclopedia/pages/Mutation_Annotation_Format_TCGAv2/> or Prediction and Annotation of Variant Effects (PAVE) <https://github.com/hartwigmedical/hmftools/tree/master/pave>. It enables conversion between SO/PAVE and MAF terms and selection of the most severe consequence where multiple ampersand (&) delimited impacts are given.

Nonparametric estimation and inference for natural direct and indirect effects by Chan, Imai, Yam and Zhang (2016) <arXiv:1601.03501>.

An R interface to version 0.3 of the ROPTLIB optimization library (see <https://www.math.fsu.edu/~whuang2/> for more information). Optimize real- valued functions over manifolds such as Stiefel, Grassmann, and Symmetric Positive Definite matrices. For details see Martin et. al. (2020) <doi:10.18637/jss.v093.i01>. Note that the optional ldr package used in some of this package's examples can be obtained from either JSS <https://www.jstatsoft.org/index.php/jss/article/view/v061i03/2886> or from the CRAN archives <https://cran.r-project.org/src/contrib/Archive/ldr/ldr_1.3.3.tar.gz>.