Composite Kernel Association Test (CKAT) is a flexible and robust kernel machine based approach to jointly test the genetic main effect and gene-treatment interaction effect for a set of single-nucleotide polymorphisms (SNPs) in pharmacogenetics (PGx) assessments embedded within randomized clinical trials.

This package implements the Bayesian calibration model described in Pratola and Chkrebtii (2018) <DOI:10.5705/ss.202016.0403> for stochastic and deterministic simulators. Additive and multiplicative discrepancy models are currently supported. See <http://www.matthewpratola.com/software> for more information and examples.

This package provides a time series usually does not have a uniform growth rate. Compound Annual Growth Rate measures the average annual growth over a given period. More details can be found in Bardhan et al. (2022) <DOI:10.18805/ag.D-5418>.

Jointly model the accuracy of cognitive responses and item choices within a Bayesian hierarchical framework as described by Culpepper and Balamuta (2015) <doi:10.1007/s11336-015-9484-7>. In addition, the package contains the datasets used within the analysis of the paper.

Implementation of different algorithms for analyzing randomly truncated data, one-sided and two-sided (i.e. doubly) truncated data. It serves to compute empirical cumulative distributions and also kernel density and hazard functions using different bandwidth selectors. Several real data sets are included.

This package provides functions and an example dataset for the psychometric theory of knowledge spaces. This package implements data analysis methods and procedures for simulating data and quasi orders and transforming different formulations in knowledge space theory. See package?DAKS for an overview.

Extended and enhanced hierarchical logistic regression models (called Huisman-Olff-Fresco in biology, see Huisman et al. 1993 Journal of Vegetation Science <doi:10.1111/jvs.12050>) models. Response curves along one-dimensional gradients including no response, monotone, plateau, unimodal and bimodal models.

This package provides simple, fast, and stable functions to fit the normal means model using empirical Bayes. For available models and details, see function ebnm(). A detailed introduction to the package is provided by Willwerscheid and Stephens (2021) <arXiv:2110.00152>.

This package provides a group-specific recommendation system to use dependency information from users and items which share similar characteristics under the singular value decomposition framework. Refer to paper A Group-Specific Recommender System <doi:10.1080/01621459.2016.1219261> for the details.

Calculate AIC's and AICc's of unimodal model (one normal distribution) and bimodal model(a mixture of two normal distributions) which fit the distribution of indices of asymmetry (IAS), and plot their density, to help determine IAS distribution is unimodal or bimodal.

This package performs likelihood criterion analysis using the Laplace regression model to determine its optimal subset of variables. The methodology is based on Guo et al. (2023), LIC criterion for optimal subset selection in distributed interval estimation <doi:10.1080/02331888.2020.1823979>.

This package provides functions to calculate hazard and survival function of Multi-Stage Clonal Expansion Models used in cancer epidemiology. For the Two-Stage Clonal Expansion Model an exact solution is implemented assuming piecewise constant parameters. Numerical solutions are provided for its extensions.

This package provides tools for non-parametric Fourier deconvolution using the N-Power Fourier Deconvolution (NPFD) method. This package includes methods for density estimation (densprf()) and sample generation (createSample()), enabling users to perform statistical analyses on mixed or replicated data sets.

This package implements projected sparse Gaussian process Kriging ('Ingram et. al.', 2008, <doi:10.1007/s00477-007-0163-9>) as an additional method for the intamap package. More details on implementation ('Barillec et. al.', 2010, <doi:10.1016/j.cageo.2010.05.008>).

The letters qe in the package title stand for "quick and easy," alluding to the convenience goal of the package. We bring together a variety of machine learning (ML) tools from standard R packages, providing wrappers with a simple, convenient, and uniform interface.

Compile Typst files using the typst-cli (<https://typst.app>) command line tool. Automatically falls back to rendering via embedded Typst from Quarto (<https://quarto.org>) if Typst is not installed. Includes utilities to check for typst-cli availability and run Typst commands.

This package provides an extension to the Partial Credit Model and Generalized Partial Credit Models which allows for an additional person parameter that characterizes the uncertainty of the person. The method was originally proposed by Tutz and Schauberger (2020) <doi:10.1177/0146621620920932>.

This package provides a shiny app for accurate estimation of vaccine induced immunogenicity with bivariate linear modeling. Method is detailed in: Lhomme, Hejblum, Lacabaratz, Wiedemann, Lelievre, Levy, Thiebaut & Richert (2020). Journal of Immunological Methods, 477:112711. <doi:10.1016/j.jim.2019.112711>.

This package implements the estimation of local (and global) association measures: Lewontin's D, Ducher's Z, pointwise mutual information, normalized pointwise mutual information and chi-squared residuals. The significance of local (and global) association is accessed using p-values estimated by permutations.

R-wrs2 offers a range of strong stats methods from Wilcox WRS functions. It implements robust t-tests, both independent and dependent, robust ANOVA, including designs with between-within subjects, quantile ANOVA, robust correlation, robust mediation, and nonparametric ANCOVA models using robust location measures.

This package provides four boolean matrix factorization (BMF) methods. BMF has many applications like data mining and categorical data analysis. BMF is also known as boolean matrix decomposition (BMD) and was found to be an NP-hard (non-deterministic polynomial-time) problem. Currently implemented methods are Asso Miettinen, Pauli and others (2008) <doi:10.1109/TKDE.2008.53>, GreConD R. Belohlavek, V. Vychodil (2010) <doi:10.1016/j.jcss.2009.05.002> , GreConDPlus R. Belohlavek, V. Vychodil (2010) <doi:10.1016/j.jcss.2009.05.002> , topFiberM A. Desouki, M. Roeder, A. Ngonga (2019) <arXiv:1903.10326>.

This package provides a robust and powerful approach is developed for replicability analysis of two Genome-wide association studies (GWASs) accounting for the linkage disequilibrium (LD) among genetic variants. The LD structure in two GWASs is captured by a four-state hidden Markov model (HMM). The unknowns involved in the HMM are estimated by an efficient expectation-maximization (EM) algorithm in combination with a non-parametric estimation of functions. By incorporating information from adjacent locations via the HMM, this approach identifies the entire clusters of genotype-phenotype associated signals, improving the power of replicability analysis while effectively controlling the false discovery rate.

This package provides easy access to historical climate data in Canada from R. Search for weather stations and download raw hourly, daily or monthly weather data across Canada from 1840 to present. Implements public API access as detailed at <https://climate.weather.gc.ca>.

Identification of hub genes in a gene co-expression network from gene expression data. The differential network analysis for two contrasting conditions leads to the identification of various types of hubs like Housekeeping, Unique to stress (Disease) and Unique to control (Normal) hub genes.