This package contains the data for the paper by L. David et al. in PNAS 2006 (PMID 16569694): 8 CEL files of Affymetrix genechips, an ExpressionSet object with the raw feature data, a probe annotation data structure for the chip and the yeast genome annotation (GFF file) that was used. In addition, some custom-written analysis functions are provided, as well as R scripts in the scripts directory.

Rank results by confident effect sizes, while maintaining False Discovery Rate and False Coverage-statement Rate control. Topconfects is an alternative presentation of TREAT results with improved usability, eliminating p-values and instead providing confidence bounds. The main application is differential gene expression analysis, providing genes ranked in order of confident log2 fold change, but it can be applied to any collection of effect sizes with associated standard errors.

Adaptive and Robust Transfer Learning (ART) is a flexible framework for transfer learning that integrates information from auxiliary data sources to improve model performance on primary tasks. It is designed to be robust against negative transfer by including the non-transfer model in the candidate pool, ensuring stable performance even when auxiliary datasets are less informative. See the paper, Wang, Wu, and Ye (2023) <doi:10.1002/sta4.582>.

Assignment of cell type labels to single-cell RNA sequencing (scRNA-seq) clusters is often a time-consuming process that involves manual inspection of the cluster marker genes complemented with a detailed literature search. This is especially challenging when unexpected or poorly described populations are present. The clustermole R package provides methods to query thousands of human and mouse cell identity markers sourced from a variety of databases.

This package provides a set of tools for evaluating clustering robustness using proportion of ambiguously clustered pairs (Senbabaoglu et al. (2014) <doi:10.1038/srep06207>), as well as similarity across methods and method stability using element-centric clustering comparison (Gates et al. (2019) <doi:10.1038/s41598-019-44892-y>). Additionally, this package enables stability-based parameter assessment for graph-based clustering pipelines typical in single-cell data analysis.

Simplifies the process of creating essential visualizations in R, offering a range of plotting functions for common chart types like violin plots, pie charts, and histograms. With an intuitive interface, users can effortlessly customize colors, labels, and styles, making it an ideal tool for both beginners and experienced data analysts. Whether exploring datasets or producing quick visual summaries, this package provides a streamlined solution for fundamental graphics in R.

It predicts any attribute (categorical) given a set of input numeric predictor values. Note that only numeric input predictors should be given. The k value can be chosen according to accuracies provided. The attribute to be predicted can be selected from the dropdown provided (select categorical attribute). This is because categorical attributes cannot be given as inputs here. A handsontable is also provided to enter the input predictor values.

The provided package implements multiple contrast tests for functional data (Munko et al., 2023, <arXiv:2306.15259>). These procedures enable us to evaluate the overall hypothesis regarding equality, as well as specific hypotheses defined by contrasts. In particular, we can perform post hoc tests to examine particular comparisons of interest. Different experimental designs are supported, e.g., one-way and multi-way analysis of variance for functional data.

This package provides a collection of NASCAR race, driver, owner and manufacturer data across the three major NASCAR divisions: NASCAR Cup Series, NXS, and NASCAR Craftsman Truck Series. The curated data begins with the 1949 season and is updated weekly during the racing season. Explore race, season, or career performance for drivers, teams, and manufacturers throughout NASCAR's history. Data was sourced with permission from DriverAverages.com.

Calculate the optimal vertex partition of a graph using the persistence as objective function. These subroutines have been used in Avellone et al. <doi:10.1007/s10288-023-00559-z> and Avellone et al. <doi:10.1016/j.ins.2025.123032>. This package is deprecated and has been superseded by the scalednap package, which provides the same functionality and additional features; new and existing users should install scalednap instead.

This package performs support vectors analysis for data sets with survival outcome. Three approaches are available in the package: The regression approach takes censoring into account when formulating the inequality constraints of the support vector problem. In the ranking approach, the inequality constraints set the objective to maximize the concordance index for comparable pairs of observations. The hybrid approach combines the regression and ranking constraints in the same model.

Asio is a cross-platform C++ library for network and low-level I/O programming that provides developers with a consistent asynchronous model using a modern C++ approach. It is also included in Boost but requires linking when used with Boost. Standalone it can be used header-only (provided a recent compiler). Asio is written and maintained by Christopher M. Kohlhoff, and released under the Boost Software License', Version 1.0.

An approach to filter out and/or identify phytoplankton cells from all particles measured via flow cytometry pigment and cell complexity information. It does this using a sequence of one-dimensional gates on pre-defined channels measuring certain pigmentation and complexity. The package is especially tuned for cyanobacteria, but will work fine for phytoplankton communities where there is at least one cell characteristic that differentiates every phytoplankton in the community.

This R package helps the user identify k-mers (e.g. di- or tri-nucleotides) present periodically in a set of genomic loci (typically regulatory elements). The functions of this package provide a straightforward approach to find periodic occurrences of k-mers in DNA sequences, such as regulatory elements. It is not aimed at identifying motifs separated by a conserved distance; for this type of analysis, please visit MEME website.

This package contains data from an observational study concerning possible effects of light daily alcohol consumption on survival and on HDL cholesterol. It also replicates various simple analyses in Rosenbaum (2025) <doi:10.1080/09332480.2025.2473291>. Finally, it includes new R code in wgtRankCef() that implements and replicates a new method for constructing evidence factors in observational block designs in Rosenbaum (2026) <doi:10.1080/01621459.2026.2624858>).

Tracking accrual in clinical trials is important for trial success. If accrual is too slow, the trial will take too long and be too expensive. If accrual is much faster than expected, time sensitive tasks such as the writing of statistical analysis plans might need to be rushed. accrualPlot provides functions to aid the tracking of accrual and predict when a trial will reach it's intended sample size.

This package provides lightweight helpers for adding gene and chemical tooltips to R Markdown', Quarto', shiny', pkgdown', and other HTML outputs. The package emits small HTML spans with module-specific data attributes and attaches the browser-side bio-tooltips JavaScript and CSS assets through htmltools'. Entity lookup and rendering are handled in the browser by bio-tooltips'; this package does not query biological databases from R during package checks.

An implementation of several functions for feature extraction in categorical time series datasets. Specifically, some features related to marginal distributions and serial dependence patterns can be computed. These features can be used to feed clustering and classification algorithms for categorical time series, among others. The package also includes some interesting datasets containing biological sequences. Practitioners from a broad variety of fields could benefit from the general framework provided by ctsfeatures'.

The gasanalyzer R package offers methods for importing, preprocessing, and analyzing data related to photosynthetic characteristics (gas exchange, chlorophyll fluorescence and isotope ratios). It translates variable names into a standard format, and can recalculate derived, physiological quantities using imported or predefined equations. The package also allows users to assess the sensitivity of their results to different assumptions used in the calculations. See also Tholen (2024) <doi:10.1093/aobpla/plae035>.

Offers various swiss maps as data frames and ggplot2 objects and gives the possibility to add layers of data on the maps. Data are publicly available from the swiss federal statistical office. In addition to the \codemaps2 object (a list of 8 swiss maps, at various levels), there are the data frames with the boundaries used to produce these maps (\codeshp_df, a list with 8 data frames).

This package provides a tool for optimizing scales of effect when modeling ecological processes in space. Specifically, the scale parameter of a distance-weighted kernel distribution is identified for all environmental layers included in the model. Includes functions to assist in model selection, model evaluation, efficient transformation of raster surfaces using fast Fourier transformation, and projecting models. For more details see Peterman (2026) <doi:10.1007/s10980-025-02267-x>.

Analyze repertory grids, a qualitative-quantitative data collection technique devised by George A. Kelly in the 1950s. Today, grids are used across various domains ranging from clinical psychology to marketing. The package contains functions to quantitatively analyze and visualize repertory grid data (e.g. Fransella', Bell', & Bannister', 2004, ISBN: 978-0-470-09080-0). The package is part of the The package is part of the <https://openrepgrid.org/> project.

This package provides a probability tree allows to compute probabilities of complex events, such as genotype probabilities in intermediate generations of inbreeding through recurrent self-fertilization (selfing). This package implements functionality to compute probability trees for two- and three-marker genotypes in the F2 to F7 selfing generations. The conditional probabilities are derived automatically and in symbolic form. The package also provides functionality to extract and evaluate the relevant probabilities.

An implementation of the selectboost algorithm (Bertrand et al. 2020, Bioinformatics', <doi:10.1093/bioinformatics/btaa855>), which is a general algorithm that improves the precision of any existing variable selection method. This algorithm is based on highly intensive simulations and takes into account the correlation structure of the data. It can either produce a confidence index for variable selection or it can be used in an experimental design planning perspective.