Spatial transcriptomic technologies have helped to resolve the connection between gene expression and the 2D orientation of tissues relative to each other. However, the limited single-cell resolution makes it difficult to highlight the most important molecular interactions in these tissues. SpaceMarkers, R/Bioconductor software, can help to find molecular interactions, by identifying genes associated with latent space interactions in spatial transcriptomics.

Suite of tools that facilitate exposure-response analysis using Bayesian methods. The package provides a streamlined workflow for fitting types of models that are commonly used in exposure-response analysis - linear and Emax for continuous endpoints, logistic linear and logistic Emax for binary endpoints, as well as performing simulation and visualization. Learn more about the workflow at <https://genentech.github.io/BayesERbook/>.

Quickly set and summarize contrasts for factors prior to regression analyses. Intended comparisons, baseline conditions, and intercepts can be explicitly set and documented without the user needing to directly manipulate matrices. Reviews and introductions for contrast coding are available in Brehm and Alday (2022)<doi:10.1016/j.jml.2022.104334> and Schad et al. (2020)<doi:10.1016/j.jml.2019.104038>.

This package provides a tool for easily matching spatial data when you have a list of place/region names. You might have a data frame that came from a spreadsheet tracking some data by suburb or state. This package can convert it into a spatial data frame ready for plotting. The actual map data is provided by other packages (or your own code).

Supports designing efficient discrete choice experiments (DCEs). Experimental designs can be formed on the basis of orthogonal arrays or search methods for optimal designs (Federov or mixed integer programs). Various methods for converting these experimental designs into a discrete choice experiment. Many efficiency measures! Draws from literature of Kuhfeld (2010) and Street et. al (2005) <doi:10.1016/j.ijresmar.2005.09.003>.

This package provides functions for the method of effect stars as proposed by Tutz and Schauberger (2013) <doi:10.1080/10618600.2012.701379>. Effect stars can be used to visualize estimates of parameters corresponding to different groups, for example in multinomial logit models. Beside the main function effectstars there exist methods for special objects, for example for vglm objects from the VGAM package.

It analyzes raster maps and other information as input/output files from the Hydrological Distributed Model GEOtop. It contains functions and methods to import maps and other keywords from geotop.inpts file. Some examples with simulation cases of GEOtop 2.x/3.x are presented in the package. Any information about the GEOtop Distributed Hydrological Model can be found in the provided documentation.

Evaluate and validate the Geboes score for histological assessment of inflammation in ulcerative colitis. The original Geboes score from Geboes, et al. (2000) <doi:10.1136/gut.47.3.404>, binary version from Li, et al. (2019) <doi:10.1093/ecco-jcc/jjz022>, and continuous version from Magro, et al. (2020) <doi:10.1093/ecco-jcc/jjz123> are all described and implemented.

This package provides a statistical method to impute the missing values in accelerometer data. The methodology includes both parametric and semi-parametric multiple imputations under the zero-inflated Poisson lognormal model. It also provides multiple functions to preprocess the accelerometer data previous to the missing data imputation. These include detecting the wearing and the non-wearing time, selecting valid days and subjects, and creating plots.

This package contains diverse functionality to extend the usage of the iSEE package, including additional classes for the panels or modes facilitating the analysis of pathway analysis results. This package does not perform pathway analysis. Instead, it provides methods to embed precomputed pathway analysis results in a SummarizedExperiment object, in a manner that is compatible with interactive visualisation in iSEE applications.

The tuberculosis R/Bioconductor package features tuberculosis gene expression data for machine learning. All human samples from GEO that did not come from cell lines, were not taken postmortem, and did not feature recombination have been included. The package has more than 10,000 samples from both microarray and sequencing studies that have been processed from raw data through a hyper-standardized, reproducible pipeline.

Generates the equiplot, an iconic dot-plot graph for visualizing inequalities, as well as three complex inequality measures: the slope index of inequality, the concentration index and the mean absolute difference to the mean. For more details see World Health Organization (2013) <https://www.who.int/docs/default-source/gho-documents/health-equity/handbook-on-health-inequality-monitoring/handbook-on-health-inequality-monitoring.pdf>.

Aids in learning statistical functions incorporating the result of calculus done with each function and how they are obtained, that is, which equation and variables are used. Also for all these equations and their related variables detailed explanations and interactive exercises are also included. All these characteristics allow to the package user to improve the learning of statistics basics by means of their use.

This package provides functions for fitting and validation of models for subgroup identification and personalized medicine / precision medicine under the general subgroup identification framework of Chen et al. (2017) <doi:10.1111/biom.12676>. This package is intended for use for both randomized controlled trials and observational studies and is described in detail in Huling and Yu (2021) <doi:10.18637/jss.v098.i05>.

This package provides three basic functions that support an implementation of Case 2 (profile case) best-worst scaling. The first is to convert an orthogonal main-effect design into questions, the second is to create a dataset suitable for analysis, and the third is to calculate count-based scores. For details, see Aizaki and Fogarty (2019) <doi:10.1016/j.jocm.2019.100171>.

Stores objects (e.g. neural networks) that are needed for using Sojourn accelerometer methods. For more information, see Lyden K, Keadle S, Staudenmayer J, & Freedson P (2014) <doi:10.1249/MSS.0b013e3182a42a2d>, Ellingson LD, Schwabacher IJ, Kim Y, Welk GJ, & Cook DB (2016) <doi:10.1249/MSS.0000000000000915>, and Hibbing PR, Ellingson LD, Dixon PM, & Welk GJ (2018) <doi:10.1249/MSS.0000000000001486>.

This is an implementation of the Future API on top of the callr package. This allows you to process futures, as defined by the future package, in parallel out of the box, on your local machine. Contrary to backends relying on the parallel package (e.g. future::multisession) and socket connections, the callr backend provided here can run more than 125 parallel R processes.

ChIPanalyser is a package to predict and understand TF binding by utilizing a statistical thermodynamic model. The model incorporates 4 main factors thought to drive TF binding: Chromatin State, Binding energy, Number of bound molecules and a scaling factor modulating TF binding affinity. Taken together, ChIPanalyser produces ChIP-like profiles that closely mimic the patterns seens in real ChIP-seq data.

An interactive web application for quality control, filtering and trimming of FASTQ files. This user-friendly tool combines a pipeline for data processing based on Biostrings and ShortRead infrastructure, with a cutting-edge visual environment. Single-Read and Paired-End files can be locally processed. Diagnostic interactive plots (CG content, per-base sequence quality, etc.) are provided for both the input and output files.

NetPathMiner is a general framework for network path mining using genome-scale networks. It constructs networks from KGML, SBML and BioPAX files, providing three network representations, metabolic, reaction and gene representations. NetPathMiner finds active paths and applies machine learning methods to summarize found paths for easy interpretation. It also provides static and interactive visualizations of networks and paths to aid manual investigation.

This package provides functions for processing and analyzing survey data from the All of Us Social Determinants of Health (AOUSDOH) program, including tools for calculating health and well-being scores, recoding variables, and simplifying survey data analysis. For more details see - Koleck TA, Dreisbach C, Zhang C, Grayson S, Lor M, Deng Z, Conway A, Higgins PDR, Bakken S (2024) <doi:10.1093/jamia/ocae214>.

Efficient Markov Chain Monte Carlo (MCMC) algorithms for the fully Bayesian estimation of vectorautoregressions (VARs) featuring stochastic volatility (SV). Implements state-of-the-art shrinkage priors following Gruber & Kastner (2025) <doi:10.1016/j.ijforecast.2025.02.001>. Efficient equation-per-equation estimation following Kastner & Huber (2020) <doi:10.1002/for.2680> and Carrerio et al. (2021) <doi:10.1016/j.jeconom.2021.11.010>.

This package implements two out-of box classifiers presented in <doi:10.1002/env.2848> for distinguishing forest and non-forest terrain images. Under these algorithms, there are frequentist approaches: one parametric, using stable distributions, and another one- non-parametric, using the squared Mahalanobis distance. The package also contains functions for data handling and building of new classifiers as well as some test data set.

This package provides tools for quantifying Traditional Ecological Knowledge (TEK), modeling TEK in decision frameworks, and designing structured decision-framing exercises in conservation and development contexts. The package implements quantitative ethnobotany indices (Use Value, Relative Frequency of Citation, etc.) but positions them within a larger framework of Bayesian modeling and participatory decision analysis. Includes critical assessment of indices limitations and case studies of participatory workshops.