Several functions for maximum likelihood estimation of various univariate and multivariate distributions. The list includes more than 100 functions for univariate continuous and discrete distributions, distributions that lie on the real line, the positive line, interval restricted, circular distributions. Further, multivariate continuous and discrete distributions, distributions for compositional and directional data, etc. Some references include Johnson N. L., Kotz S. and Balakrishnan N. (1994). "Continuous Univariate Distributions, Volume 1" <ISBN:978-0-471-58495-7>, Johnson, Norman L. Kemp, Adrianne W. Kotz, Samuel (2005). "Univariate Discrete Distributions". <ISBN:978-0-471-71580-1> and Mardia, K. V. and Jupp, P. E. (2000). "Directional Statistics". <ISBN:978-0-471-95333-3>.

Flexible, mechanistic, and spatially explicit simulator of metacommunities. It extends our previous package - rangr (see <https://github.com/ropensci/rangr>), which implemented a mechanistic virtual species simulator integrating population dynamics and dispersal. The mrangr package adds the ability to simulate multiple species interacting through an asymmetric matrix of pairwise relationships, allowing users to model all types of biotic interactions â competitive, facilitative, or neutral â within spatially explicit virtual environments. This work was supported by the National Science Centre, Poland, grant no. 2018/29/B/NZ8/00066 and the PoznaÅ Supercomputing and Networking Centre (grant no. pl0090-01).

Subset a control group to match an intervention group on a set of features using multivariate matching and propensity score calipers. Based on methods in Rosenbaum and Rubin (1985).

Data sets related to the Islas Malvinas /// Sets de datos relacionados a las Islas Malvinas - La Nación Argentina ratifica su legà tima e imprescriptible soberanà a sobre las islas Malvinas, Georgias del Sur y Sándwich del Sur y los espacios marà timos e insulares correspondientes, por ser parte integrante del territorio nacional. La recuperación de dichos territorios y el ejercicio pleno de la soberanà a, respetando el modo de vida de sus habitantes y conforme a los principios del Derecho Internacional, constituyen un objetivo permanente e irrenunciable del pueblo argentino.

This package provides a set of tools for fitting Markov-modulated linear regression, where responses Y(t) are time-additive, and model operates in the external environment, which is described as a continuous time Markov chain with finite state space. Model is proposed by Alexander Andronov (2012) <arXiv:1901.09600v1> and algorithm of parameters estimation is based on eigenvalues and eigenvectors decomposition. Markov-switching regression models have the same idea of varying the regression parameters randomly in accordance with external environment. The difference is that for Markov-modulated linear regression model the external environment is described as a continuous-time homogeneous irreducible Markov chain with known parameters while switching models consider Markov chain as unobserved and estimation procedure involves estimation of transition matrix. These models have significant differences in terms of the analytical approach. Also, package provides a set of data simulation tools for Markov-modulated linear regression (for academical/research purposes). Research project No. 1.1.1.2/VIAA/1/16/075.

Computing metabolite set enrichment analysis (MSEA) (Yamamoto, H. et al. (2014) <doi:10.1186/1471-2105-15-51>), single sample enrichment analysis (SSEA) (Yamamoto, H. (2023) <doi:10.51094/jxiv.262>) and over-representation analysis (ORA) that accounts for undetected metabolites (Yamamoto, H. (2024) <doi:10.51094/jxiv.954>).

Model selection and averaging for regression and mixtures, inclusing Bayesian model selection and information criteria (BIC, EBIC, AIC, GIC).

Fits generalized linear models, Cox proportional-hazards models, log-rank tests, generalized estimating equations, mixed models with repeated measures, Kaplan-Meier curves, quantile differences, and hierarchical net-benefit (win-difference) and log win-ratio statistics jointly across multiple endpoints, and returns the full asymptotic covariance matrix linking them. Implements PATED (Prognostic Assisted Treatment Effect Detection), a randomized-trial method that exploits balanced prognostic covariates to tighten standard errors and increase statistical power without introducing bias.

Geospatial shapefile data of China administrative divisions to the county/district-level.

Perform multi-trait rare-variant association tests using the summary statistics and adjust for possible sample overlap. Package is based on "Multi-Trait Analysis of Rare-Variant Association Summary Statistics using MTAR" by Luo, L., Shen, J., Zhang, H., Chhibber, A. Mehrotra, D.V., Tang, Z., 2019 (submitted).

This package provides tools that extend the functionality of the RODBC package to work with Microsoft SQL Server databases. Makes it easier to browse the database and examine individual tables and views.

This package provides a multi action button for usage in shiny applications.

Estimates multivariate subgaussian stable densities and probabilities as well as generates random variates using product distribution theory. A function for estimating the parameters from data to fit a distribution to data is also provided, using the method from Nolan (2013) <doi:10.1007/s00180-013-0396-7>.

Simulate forest hydrology, forest function and dynamics over landscapes [De Caceres et al. (2015) <doi:10.1016/j.agrformet.2015.06.012>]. Parallelization is allowed in several simulation functions and simulations may be conducted including spatial processes such as lateral water transfer and seed dispersal.

Wrapper around the Unix join facility which is more efficient than the built-in R routine merge(). The package enables the joining of multiple files on disk at once. The files can be compressed and various filters can be deployed before joining. Compiles only under Unix.

Process OpenPose human body keypoints for computer vision, including data structuring and user-defined linear transformations for standardization. It optionally, includes metadata extraction from filenames in the UCLA NewsScape archive.

This package implements differential methylation region (DMR) detection using a multistage Markov chain Monte Carlo (MCMC) algorithm based on the alpha-skew generalized normal (ASGN) distribution. Version 0.2.0 removes the Anderson-Darling test stage, improves computational efficiency of the core ASGN and multistage MCMC routines, and adds convenience functions for summarizing and visualizing detected DMRs. The methodology is based on Yang (2025) <https://www.proquest.com/docview/3218878972>.

Query, extract, and plot genealogical data from The Mathematics Genealogy Project <https://mathgenealogy.org/>. Data is gathered from the WebSocket server run by the geneagrapher-core project <https://github.com/davidalber/geneagrapher-core>.

It can be used to create/encode molecular "license-plates" from sequences and to also decode the "license-plates" back to sequences. While initially created for transfer RNA-derived small fragments (tRFs), this tool can be used for any genomic sequences including but not limited to: tRFs, microRNAs, etc. The detailed information can reference to Pliatsika V, Loher P, Telonis AG, Rigoutsos I (2016) <doi:10.1093/bioinformatics/btw194>. It can also be used to annotate tRFs. The detailed information can reference to Loher P, Telonis AG, Rigoutsos I (2017) <doi:10.1038/srep41184>.

Used for general multiple mediation analysis. The analysis method is described in Yu and Li (2022) (ISBN: 9780367365479) "Statistical Methods for Mediation, Confounding and Moderation Analysis Using R and SAS", published by Chapman and Hall/CRC; and Yu et al.(2017) <DOI:10.1016/j.sste.2017.02.001> "Exploring racial disparity in obesity: a mediation analysis considering geo-coded environmental factors", published on Spatial and Spatio-temporal Epidemiology, 21, 13-23.

This package provides functions to run fixed effects or random effects multivariate meta-analysis.

This package provides methods to estimate serial intervals and time-varying case reproduction numbers from infectious disease outbreak data. Serial intervals measure the time between symptom onset in linked transmission pairs, while case reproduction numbers quantify how many secondary cases each infected individual generates over time. These parameters are essential for understanding transmission dynamics, evaluating control measures, and informing public health responses. The package implements the maximum likelihood framework from Vink et al. (2014) <doi:10.1093/aje/kwu209> for serial interval estimation and the retrospective method from Wallinga & Lipsitch (2007) <doi:10.1098/rspb.2006.3754> for reproduction number estimation. Originally developed for scabies transmission analysis but applicable to other infectious diseases including influenza, COVID-19, and emerging pathogens. Designed for epidemiologists, public health researchers, and infectious disease modelers working with outbreak surveillance data.

This package provides a set of functions to calculate solar irradiance and insolation on Mars horizontal and inclined surfaces. Based on NASA Technical Memoranda 102299, 103623, 105216, 106321, and 106700, i.e. the canonical Mars solar radiation papers.

Analyzing longitudinal clinical data from Electronic Health Records (EHRs) using linear mixed models (LMM) and visualizing the results as networks. It includes functions for fitting LMM, normalizing adjacency matrices, and comparing networks. The package is designed for researchers in clinical and biomedical fields who need to model longitudinal data and explore relationships between variables For more details see Bates et al. (2015) <doi:10.18637/jss.v067.i01>.