Dynamic Mode Decomposition (DMD) with Koopman operator theory extensions, powered by a Rust backend via extendr'. Provides standard DMD as described in Schmid (2010) <doi:10.1017/S0022112010001217>, DMD with control for forced linear systems following Proctor, Brunton, and Kutz (2016) <doi:10.1137/15M1013857>, Extended DMD with lifting functions, Hankel-DMD via time-delay embedding, Generalized Laplace Analysis for direct eigenfunction computation, and harmonic time averages and mesochronic harmonic plots for phase space analysis as developed in Mezic (2020) <doi:10.48550/arXiv.2009.05883>. Includes built-in area-preserving and chaotic maps for experimentation.

This package provides functions for cost-optimal control charts with a focus on health care applications. Compared to assumptions in traditional control chart theory, here, we allow random shift sizes, random repair and random sampling times. The package focuses on X-bar charts with a sample size of 1 (representing the monitoring of a single patient at a time). The methods are described in Zempleni et al. (2004) <doi:10.1002/asmb.521>, Dobi and Zempleni (2019) <doi:10.1002/qre.2518> and Dobi and Zempleni (2019) <http://ac.inf.elte.hu/Vol_049_2019/129_49.pdf>.

Computational infrastructure for biogeography, community ecology, and biodiversity conservation (Daru et al. 2020) <doi:10.1111/2041-210X.13478>. It is based on the methods described in Daru et al. (2020) <doi:10.1038/s41467-020-15921-6>. The original conceptual work is described in Daru et al. (2017) <doi:10.1016/j.tree.2017.08.013> on patterns and processes of biogeographical regionalization. Additionally, the package contains fast and efficient functions to compute more standard conservation measures such as phylogenetic diversity, phylogenetic endemism, evolutionary distinctiveness and global endangerment, as well as compositional turnover (e.g., beta diversity).

This package provides a suite of helper functions to support Bayesian Kernel Machine Regression (BKMR) analyses in environmental health research. It enables the simulation of realistic multivariate exposure data using Multivariate Skewed Gamma distributions, estimation of distributional parameters by subgroup, and application of adaptive, data-driven thresholds for feature selection via Posterior Inclusion Probabilities (PIPs). It is especially suited for handling skewed exposure data and enhancing the interpretability of BKMR results through principled variable selection. The methodology is described in Hasan et al. (2025) <doi:10.1080/00949655.2025.2608780> and <doi:10.1101/2025.04.14.25325822>.

This package provides basic functions that support an implementation of object case (Case 1) best-worst scaling: a function for converting a two-level orthogonal main-effect design/balanced incomplete block design into questions; two functions for creating a data set suitable for analysis; a function for calculating count-based scores; a function for calculating shares of preference; and a function for generating artificial responses to questions. See Louviere et al. (2015) <doi:10.1017/CBO9781107337855> for details on best-worst scaling, and Aizaki and Fogarty (2023) <doi:10.1016/j.jocm.2022.100394> for the package.

Assay for Transpose-Accessible Chromatin using sequencing (ATAC-seq) is a technique to assess genome-wide chromatin accessibility by probing open chromatin with hyperactive mutant Tn5 Transposase that inserts sequencing adapters into open regions of the genome. ATACseqTFEA is an improvement of the current computational method that detects differential activity of transcription factors (TFs). ATACseqTFEA not only uses the difference of open region information, but also (or emphasizes) the difference of TFs footprints (cutting sites or insertion sites). ATACseqTFEA provides an easy, rigorous way to broadly assess TF activity changes between two conditions.

Generalized computational algorithms for competing risks analysis, stress-strength reliability modeling, optimal designs, and reliability acceptance sampling plans under various hybrid censoring schemes. Includes data generation routines, Maximum Likelihood Estimation (MLE) with seven optimization algorithms ('Newton-Raphson', BFGS', BFGSR', BHHH', SANN', CG', and Nelder-Mead'), Bayesian inference via Gibbs sampling and Metropolis-Hastings MCMC, Importance Sampling, and Lindley asymptotic approximation. Visualization functions generate histograms, dot plots, and autocorrelation plots for model validation. Methodology and design principles are based on Balakrishnan', Cramer', and Kundu (2023, "Hybrid Censoring Know-How: Designs and Implementations", Academic Press, ISBN:978-0-12-398387-9).

This package provides a function that facilitates fitting three types of models for contrast-based Bayesian Network Meta Analysis. The first model is that which is described in Lu and Ades (2006) <doi:10.1198/016214505000001302>. The other two models are based on a Bayesian nonparametric methods that permit ties when comparing treatment or for a treatment effect to be exactly equal to zero. In addition to the model fits, the package provides a summary of the interplay between treatment effects based on the procedure described in Barrientos, Page, and Lin (2023) <doi:10.48550/arXiv.2207.06561>.

Three semi-parametric methods for detection of outliers in environmental data based on kernel regression and subsequent analysis of smoothing residuals. The first method (Campulova, Michalek, Mikuska and Bokal (2018) <DOI: 10.1002/cem.2997>) analyzes the residuals using changepoint analysis, the second method is based on control charts (Campulova, Veselik and Michalek (2017) <DOI: 10.1016/j.apr.2017.01.004>) and the third method (Holesovsky, Campulova and Michalek (2018) <DOI: 10.1016/j.apr.2017.06.005>) analyzes the residuals using extreme value theory (Holesovsky, Campulova and Michalek (2018) <DOI: 10.1016/j.apr.2017.06.005>).

Supports the assessment of the degree of conservation of taxa in conservation systems, both in ex situ (in genebanks, botanical gardens, and other repositories), and in situ (in protected natural areas). Methods are described in Carver et al. (2021) <doi:10.1111/ecog.05430>, building on Khoury et al. (2020) <doi:10.1073/pnas.2007029117>, Khoury et al. (2019) <doi:10.1016/j.ecolind.2018.11.016>, Khoury et al. (2019) <doi:10.1111/DDI.13008>, Castaneda-Alvarez et al. (2016) <doi:10.1038/nplants.2016.22>, and Ramirez-Villegas et al. (2010) <doi:10.1371/journal.pone.0013497>.

Enables the user to find the country, region, district, city, coordinates, zip code, time zone, ISP, domain name, connection type, area code, weather, Mobile Country Codes (MCC), Mobile Network Code (MNC), mobile brand name, elevation, usage type, address type, IAB category and Autonomous system number (ASN) that any IP address or hostname originates from. Supported IPv4 and IPv6. Please visit <https://www.ip2location.com> to learn more. You may also want to visit <https://lite.ip2location.com> for free database download. This package requires IP2Location Python module. At the terminal, please run pip install IP2Location to install the module.

This package provides a curated reference list of countries and territories with classifications for Small Island Developing States (SIDS), sub-national island jurisdictions (SNIJ), World Bank region and income group, and political association. Sub-sovereign cases such as Aruba, Curacao, Bonaire, Sint Maarten, the French overseas territories, and Aaland Islands are represented with disambiguating codes that standard country-code packages often collapse or omit. Provides predicate helpers and a tidy joiner intended to extend rather than replace countrycode'. Source data is maintained at <https://github.com/University-of-Aruba/island-research-reference-data> and licensed CC BY 4.0.

This package provides model-aware behavioral validation and audit certificates for statistical analyses. Controlled transformations and model-specific diagnostic checks are organized across five domains: computational integrity, numerical stability, design adequacy, assumption screening, and influence stability. Supported workflows include linear models, generalized linear models, classical and repeated-measures analyses of variance, mixed-effects models fitted using lme4 or glmmTMB', and survival models fitted using survival'. Checks are selected according to registered applicability conditions for each model class. The resulting certificates describe computational behavior and selected diagnostic findings; they do not establish causal validity, model correctness, or scientific appropriateness.

Computes how the correlation between 2 time-series changes over time. To do so, the package follows the method from Choi & Shin (2021) <doi:10.1007/s42952-020-00073-6>. It performs a non-parametric kernel smoothing (using a common bandwidth) of all underlying components required for the computation of a correlation coefficient (i.e., x, y, x^2, y^2, xy). An automatic selection procedure for the bandwidth parameter is implemented. Alternative kernels can be used (Epanechnikov, box and normal). Both Pearson and Spearman correlation coefficients can be estimated and change in correlation over time can be tested.

G-quadruplexes (G4s) are unique nucleic acid secondary structures predominantly found in guanine-rich regions and have been shown to be involved in various biological regulatory processes. G4SNVHunter is an R package designed to rapidly identify genomic sequences with G4-forming propensity and to accurately screen user-provided single nucleotide variants—as well as other small-scale variants such as indels and MNVs—for their potential to destabilize these structures. This allows researchers to then screen these critical variants for deeper study, digging into how they might influence biological functions—think gene regulation, for instance—by impairing G4 formation propensity.

This package provides a package for detecting differential methylation. It exploits a Bayesian hidden Markov model that incorporates location dependence among genomic loci, unlike most existing methods that assume independence among observations. Bayesian priors are applied to permit information sharing across an entire chromosome for improved power of detection. The direct output of our software package is the best sequence of methylation states, eliminating the use of a subjective, and most of the time an arbitrary, threshold of p-value for determining significance. At last, our methodology does not require replication in either or both of the two comparison groups.

This package provides a set of utilities for matching products in different classification codes used in international trade research. It supports concordance between the Harmonized System (HS0, HS1, HS2, HS3, HS4, HS5, HS combined), the Standard International Trade Classification (SITC1, SITC2, SITC3, SITC4), the North American Industry Classification System (NAICS combined), as well as the Broad Economic Categories (BEC), the International Standard of Industrial Classification (ISIC), and the Standard Industrial Classification (SIC). It also provides code nomenclature/descriptions look-up, Rauch classification look-up (via concordance to SITC2), and trade elasticity look-up (via concordance to HS0 or SITC3 codes).

In meta regression sometimes the studies have multiple effects that are correlated. For this reason cluster robust standard errors must be computed. However, since the clusters are unbalanced the wild bootstrap is suggested. See Oczkowski E. and Doucouliagos H. (2015). "Wine prices and quality ratings: a meta-regression analysis". American Journal of Agricultural Economics, 97(1): 103--121. <doi:10.1093/ajae/aau057> and Cameron A. C., Gelbach J. B. and Miller D. L. (2008). "Bootstrap-based improvements for inference with clustered errors". The Review of Economics and Statistics, 90(3): 414--427. <doi:10.1162/rest.90.3.414>.

Testing of soil for the contents of organic carbon, and available macro- and micro-nutrients is a crucial part of soil fertility assessment. This package computes some routinely tested soil properties viz. organic carbon (C), total nitrogen (N), available N, mineral N, available phosphorus (P), available potassium (K), available iron (Fe), available zinc (Zn), available manganese (Mn), available copper (Cu), and available nickel (Ni) in soil based on laboratory analysis data obtained by most commonly followed protocols. Besides, it can also draw standard curves based on absorption/emission vs. concentration data, and give out unknown concentrations from absorption/emission readings.

Forecasting competitions are of increasing importance as a mean to learn best practices and gain knowledge. Data leakage is one of the most common issues that can often be found in competitions. Data leaks can happen when the training data contains information about the test data. For example: randomly chosen blocks of time series are concatenated to form a new time series, scale-shifts, repeating patterns in time series, white noise is added in the original time series to form a new time series, etc. tsdataleaks package can be used to detect data leakages in a collection of time series.

This package provides R users with direct access to genomic and clinical data from the cBioPortal web resource via user-friendly functions that wrap cBioPortal's existing API endpoints <https://www.cbioportal.org/api/swagger-ui/index.html>. Users can browse and query genomic data on mutations, copy number alterations and fusions, as well as data on tumor mutational burden ('TMB'), microsatellite instability status ('MSI'), FACETS and select clinical data points (depending on the study). See <https://www.cbioportal.org/> and Gao et al., (2013) <doi:10.1126/scisignal.2004088> for more information on the cBioPortal web resource.

Reads variant call format (VCF) files in a caller-agnostic way, annotates variants with flanking sequence context and transcriptional strand, and builds mutational-spectrum catalogs of single base substitutions (SBS), doublet base substitutions (DBS), and small insertions and deletions (indels, ID) at several resolutions (SBS96, SBS192, SBS1536, DBS78, DBS136, DBS144, ID83, ID89, ID166, ID476) and in both counts and density representations. Successor to the numerical core of the ICAMS package with plotting, shiny', and portable document format (PDF) reporting removed; plotting is provided separately by mSigPlot'. Used in the preparation of Rozen et al. (2026) <doi:10.5281/zenodo.18451842>.

Two method new of multigroup and simulation of data. The first technique called multigroup PCA (mgPCA) this multivariate exploration approach that has the idea of considering the structure of groups and / or different types of variables. On the other hand, the second multivariate technique called Multigroup Dimensionality Reduction (MDR) it is another multivariate exploration method that is based on projections. In addition, a method called Single Dimension Exploration (SDE) was incorporated for to analyze the exploration of the data. It could help us in a better way to observe the behavior of the multigroup data with certain variables of interest.

This package provides functions and graphics for projecting daily incidence based on past incidence, and estimates of the serial interval and reproduction number. Projections are based on a branching process using a Poisson-distributed number of new cases per day, similar to the model used for estimating R in EpiEstim or in earlyR', and described by Nouvellet et al. (2017) <doi:10.1016/j.epidem.2017.02.012>. The package provides the S3 class projections which extends matrix', with accessors and additional helpers for handling, subsetting, merging, or adding these objects, as well as dedicated printing and plotting methods.