This package provides a unified parallelization framework for multiple backends. This package is designed for internal package and interactive usage. The main operation is parallel mapping over lists. It supports local, multicore, mpi and BatchJobs mode. It allows tagging of the parallel operation with a level name that can be later selected by the user to switch on parallel execution for exactly this operation.

This package provides methods to estimate dynamic treatment regimes using Interactive Q-Learning, Q-Learning, weighted learning, and value-search methods based on Augmented Inverse Probability Weighted Estimators and Inverse Probability Weighted Estimators. Dynamic Treatment Regimes: Statistical Methods for Precision Medicine, Tsiatis, A. A., Davidian, M. D., Holloway, S. T., and Laber, E. B., Chapman & Hall/CRC Press, 2020, ISBN:978-1-4987-6977-8.

Empirical Bayes methods for learning prior distributions from data. An unknown prior distribution (g) has yielded (unobservable) parameters, each of which produces a data point from a parametric exponential family (f). The goal is to estimate the unknown prior ("g-modeling") by deconvolution and Empirical Bayes methods. Details and examples are in the paper by Narasimhan and Efron (2020, <doi:10.18637/jss.v094.i11>).

This package provides a collection of functions for computing fairness metrics for machine learning and statistical models, including confidence intervals for each metric. The package supports the evaluation of group-level fairness criterion commonly used in fairness research, particularly in healthcare. It is based on the overview of fairness in machine learning written by Gao et al (2024) <doi:10.48550/arXiv.2406.09307>.

Software for performing the reduction, exploratory and model selection phases of the procedure proposed by Cox, D.R. and Battey, H.S. (2017) <doi:10.1073/pnas.1703764114> for sparse regression when the number of potential explanatory variables far exceeds the sample size. The software supports linear regression, likelihood-based fitting of generalized linear regression models and the proportional hazards model fitted by partial likelihood.

Classical Ising Model is a land mark system in statistical physics.The model explains the physics of spin glasses and magnetic materials, and cooperative phenomenon in general, for example phase transitions and neural networks.This package provides utilities to simulate one dimensional Ising Model with Metropolis and Glauber Monte Carlo with single flip dynamics in periodic boundary conditions. Utility functions for exact solutions are provided.

R Client for the Microsoft Cognitive Services Web Language Model REST API, including Break Into Words, Calculate Conditional Probability, Calculate Joint Probability, Generate Next Words, and List Available Models. A valid account MUST be registered at the Microsoft Cognitive Services website <https://www.microsoft.com/cognitive-services/> in order to obtain a (free) API key. Without an API key, this package will not work properly.

Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the rxode2 package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>). This package is for ggplot2 plotting methods for nlmixr2 objects.

Set of functions designed to help in the analysis of TDP sensors. Features includes dates and time conversion, weather data interpolation, daily maximum of tension analysis and calculations required to convert sap flow density data to sap flow rates at the tree and plot scale (For more information see : Granier (1985) <DOI:10.1051/forest:19850204> & Granier (1987) <DOI:10.1093/treephys/3.4.309>).

Tests the hypothesis that variances are homogeneous or not using bootstrap. The procedure uses a variance-based statistic, and is derived from a normal-theory test. The test equivalently expressed the hypothesis as a function of the log contrasts of the population variances. A box-type acceptance region is constructed to test the hypothesis. See Cahoy (2010) \doi10.1016/j.csda.2010.04.012.

An integrated suite of tools for creating, maintaining, and reusing FAIR (Findable, Accessible, Interoperable, Reusable) theories. Designed to support transparent and collaborative theory development, the package enables users to formalize theories, track changes with version control, assess pre-empirical coherence, and derive testable hypotheses. Aligning with open science principles and workflows, theorytools facilitates the systematic improvement of theoretical frameworks and enhances their discoverability and usability.

Adding some at-present missing functionality, or functions unlikely to be added to the base xpose package. This includes some diagnostic plots that have been missing in translation from xpose4', but also some useful features that truly extend the capabilities of what can be done with xpose'. These extensions include the concept of a set of xpose objects, and diagnostics for likelihood-based models.

Blacksheep is a tool designed for outlier analysis in the context of pairwise comparisons in an effort to find distinguishing characteristics from two groups. This tool was designed to be applied for biological applications such as phosphoproteomics or transcriptomics, but it can be used for any data that can be represented by a 2D table, and has two sub populations within the table to compare.

The classification protocol starts with a feature selection step and continues with nearest-centroid classification. The accurarcy of the predictor can be evaluated using training and test set validation, leave-one-out cross-validation or in a multiple random validation protocol. Methods for calculation and visualization of continuous prediction scores allow to balance sensitivity and specificity and define a cutoff value according to clinical requirements.

The crisprVerse is a modular ecosystem of R packages developed for the design and manipulation of CRISPR guide RNAs (gRNAs). All packages share a common language and design principles. This package is designed to make it easy to install and load the crisprVerse packages in a single step. To learn more about the crisprVerse, visit <https://www.github.com/crisprVerse>.

This package parses a fitted R model object, and returns a formula in Tidy Eval code that calculates the predictions. It works with several database backends because it leverages dplyr and dbplyr for the final SQL translation of the algorithm. It currently supports lm(), glm(), randomForest(), ranger(), earth(), xgb.Booster.complete(), cubist(), and ctree() models.

MsgPack header files are provided for use by R packages, along with the ability to access, create and alter MsgPack objects directly from R. MsgPack is an efficient binary serialization format. It lets you exchange data among multiple languages like JSON but it is faster and smaller. Small integers are encoded into a single byte, and typical short strings require only one extra byte in addition to the strings themselves. This package provides headers from the msgpack-c implementation for C and C++(11) for use by R, particularly Rcpp'. The included msgpack-c headers are licensed under the Boost Software License (Version 1.0); the code added by this package as well the R integration are licensed under the GPL (>= 2). See the files COPYRIGHTS and AUTHORS for a full list of copyright holders and contributors to msgpack-c'.

Calculates evaluation metrics for implicit-feedback recommender systems that are based on low-rank matrix factorization models, given the fitted model matrices and data, thus allowing to compare models from a variety of libraries. Metrics include P@K (precision-at-k, for top-K recommendations), R@K (recall at k), AP@K (average precision at k), NDCG@K (normalized discounted cumulative gain at k), Hit@K (from which the Hit Rate is calculated), RR@K (reciprocal rank at k, from which the MRR or mean reciprocal rank is calculated), ROC-AUC (area under the receiver-operating characteristic curve), and PR-AUC (area under the precision-recall curve). These are calculated on a per-user basis according to the ranking of items induced by the model, using efficient multi-threaded routines. Also provides functions for creating train-test splits for model fitting and evaluation.

The proposed event-driven approach for Bayesian two-stage single-arm phase II trial design is a novel clinical trial design and can be regarded as an extension of the Simonâ s two-stage design with the time-to-event endpoint. This design is motivated by cancer clinical trials with immunotherapy and molecularly targeted therapy, in which time-to-event endpoint is often a desired endpoint.

These experimental expression data (5 leukemic CLL B-lymphocyte of aggressive form from GSE39411', <doi:10.1073/pnas.1211130110>), after B-cell receptor stimulation, are used as examples by packages such as the Cascade one, a modeling tool allowing gene selection, reverse engineering, and prediction in cascade networks. Jung, N., Bertrand, F., Bahram, S., Vallat, L., and Maumy-Bertrand, M. (2014) <doi:10.1093/bioinformatics/btt705>.

Cure dependent censoring regression models for long-term survival multivariate data. These models are based on extensions of the frailty models, capable to accommodating the cure fraction and the dependence between failure and censoring times, with Weibull and piecewise exponential marginal distributions. Theoretical details regarding the models implemented in the package can be found in Schneider et al. (2022) <doi:10.1007/s10651-022-00549-0>.

Displays a weighted undirected food graph from an adjacency matrix. Can perform confidence-interval bootstrap inference with mutual information or maximal information coefficient. Based on my Master 1 internship at the Bordeaux Population Health center. References : Reshef et al. (2011) <doi:10.1126/science.1205438>, Meyer et al. (2008) <doi:10.1186/1471-2105-9-461>, Liu et al. (2016) <doi:10.1371/journal.pone.0158247>.

Approaches for incorporating time into network analysis. Methods include: construction of time-ordered networks (temporal graphs); shortest-time and shortest-path-length analyses; resource spread calculations; data resampling and rarefaction for null model construction; reduction to time-aggregated networks with variable window sizes; application of common descriptive statistics to these networks; vector clock latencies; and plotting functionalities. The package supports <doi:10.1371/journal.pone.0020298>.

It includes functions like tropical addition, tropical multiplication for vectors and matrices. In tropical algebra, the tropical sum of two numbers is their minimum and the tropical product of two numbers is their ordinary sum. For more information see also I. Simon (1988) Recognizable sets with multiplicities in the tropical semi ring: Volume 324 Lecture Notes I Computer Science, pages 107-120 <doi: 10.1007/BFb0017135>.