Arrays of structured data types can require large volumes of disk space to store. Blosc is a library that provides a fast and efficient way to compress such data. It is often applied in storage of n-dimensional arrays, such as in the case of the geo-spatial zarr file format. This package can be used to compress and decompress data using Blosc'.

Parse a BibTeX file to a data.frame to make it accessible for further analysis and visualization.

This package implements functions for multi-class discriminant analysis using binary predictors, for corresponding variable selection, and for dichotomizing continuous data.

Collection of tools to make R more convenient. Includes tools to summarize data using statistics not available with base R and manipulate objects for analyses.

Inflammation can affect many micronutrient biomarkers and can thus lead to incorrect diagnosis of individuals and to over- or under-estimate the prevalence of deficiency in a population. Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) is a multi-agency and multi-country partnership designed to improve the interpretation of nutrient biomarkers in settings of inflammation and to generate context-specific estimates of risk factors for anemia (Suchdev (2016) <doi:10.3945/an.115.010215>). In the past few years, BRINDA published a series of papers to provide guidance on how to adjust micronutrient biomarkers, retinol binding protein, serum retinol, serum ferritin by Namaste (2020), soluble transferrin receptor (sTfR), serum zinc, serum and Red Blood Cell (RBC) folate, and serum B-12, using inflammation markers, alpha-1-acid glycoprotein (AGP) and/or C-Reactive Protein (CRP) by Namaste (2020) <doi:10.1093/ajcn/nqaa141>, Rohner (2017) <doi:10.3945/ajcn.116.142232>, McDonald (2020) <doi:10.1093/ajcn/nqz304>, and Young (2020) <doi:10.1093/ajcn/nqz303>. The BRINDA inflammation adjustment method mainly focuses on Women of Reproductive Age (WRA) and Preschool-age Children (PSC); however, the general principle of the BRINDA method might apply to other population groups. The BRINDA R package is a user-friendly all-in-one R package that uses a series of functions to implement BRINDA adjustment method, as described above. The BRINDA R package will first carry out rigorous checks and provides users guidance to correct data or input errors (if they occur) prior to inflammation adjustments. After no errors are detected, the package implements the BRINDA inflammation adjustment for up to five micronutrient biomarkers, namely retinol-binding-protein, serum retinol, serum ferritin, sTfR, and serum zinc (when appropriate), using inflammation indicators of AGP and/or CRP for various population groups. Of note, adjustment for serum and RBC folate and serum B-12 is not included in the R package, since evidence shows that no adjustment is needed for these micronutrient biomarkers in either WRA or PSC groups (Young (2020) <doi:10.1093/ajcn/nqz303>).

Efficient methods for Bayesian inference of state space models via Markov chain Monte Carlo (MCMC) based on parallel importance sampling type weighted estimators (Vihola, Helske, and Franks, 2020, <doi:10.1111/sjos.12492>), particle MCMC, and its delayed acceptance version. Gaussian, Poisson, binomial, negative binomial, and Gamma observation densities and basic stochastic volatility models with linear-Gaussian state dynamics, as well as general non-linear Gaussian models and discretised diffusion models are supported. See Helske and Vihola (2021, <doi:10.32614/RJ-2021-103>) for details.

Convert fitted objects from various R mixed-model packages into tidy data frames along the lines of the broom package. The package provides three S3 generics for each model: tidy(), which summarizes a model's statistical findings such as coefficients of a regression; augment(), which adds columns to the original data such as predictions, residuals and cluster assignments; and glance(), which provides a one-row summary of model-level statistics.

This package provides tools for Dating Business Cycles using Harding-Pagan (Quarterly Bry-Boschan) method and various plotting features.

This package implements Bayesian marginal structural models for causal effect estimation with time-varying treatment and confounding. It includes an extension to handle informative right censoring. The Bayesian importance sampling weights are estimated using JAGS. See Saarela (2015) <doi:10.1111/biom.12269> for methodological details.

This package implements a wide variety of one- and two-parameter Bayesian CRM designs. The program can run interactively, allowing the user to enter outcomes after each cohort has been recruited, or via simulation to assess operating characteristics. See Sweeting et al. (2013): <doi:10.18637/jss.v054.i13>.

Under- and over-dispersed binary data are modeled using an extended Poisson process model (EPPM) appropriate for binary data. A feature of the model is that the under-dispersion relative to the binomial distribution only needs to be greater than zero, but the over-dispersion is restricted compared to other distributional models such as the beta and correlated binomials. Because of this, the examples focus on under-dispersed data and how, in combination with the beta or correlated distributions, flexible models can be fitted to data displaying both under- and over-dispersion. Using Generalized Linear Model (GLM) terminology, the functions utilize linear predictors for the probability of success and scale-factor with various link functions for p, and log link for scale-factor, to fit a variety of models relevant to areas such as bioassay. Details of the EPPM are in Faddy and Smith (2012) <doi:10.1002/bimj.201100214> and Smith and Faddy (2019) <doi:10.18637/jss.v090.i08>.

This package provides a box compatible custom language parser for the languageserver package to provide completion and signature hints in code editors.

BAYesian inference for MEDical designs in R. Functions for the computation of Bayes factors for common biomedical research designs. Implemented are functions to test the equivalence (equiv_bf), non-inferiority (infer_bf), and superiority (super_bf) of an experimental group compared to a control group on a continuous outcome measure. Bayes factors for these three tests can be computed based on raw data (x, y) or summary statistics (n_x, n_y, mean_x, mean_y, sd_x, sd_y [or ci_margin and ci_level]).

Implementation of the record linkage methodology proposed by Sadinle (2017) <doi:10.1080/01621459.2016.1148612>. It handles the bipartite record linkage problem, where two duplicate-free datafiles are to be merged.

Estimating the average causal effect based on the Bayesian Adjustment for Confounding (BAC) algorithm.

Bayesian Generalized Linear Regression.

Efficient sampling for Gaussian linear regression with arbitrary priors, Hahn, He and Lopes (2018) <arXiv:1806.05738>.

Primarily created as an easy and understanding way to do basic sequences surrounding the central dogma of molecular biology.

Tool to perform Bayesian inference of carcass processing/transport strategy and bone attrition from archaeofaunal skeletal profiles characterized by percentages of MAU (Minimum Anatomical Units). The approach is based on a generative model for skeletal profiles that replicates the two phases of formation of any faunal assemblage: initial accumulation as a function of human transport strategies and subsequent attrition.Two parameters define this model: 1) the transport preference (alpha), which can take any value between - 1 (mostly axial contribution) and 1 (mostly appendicular contribution) following strategies constructed as a function of butchering efficiency of different anatomical elements and the results of ethnographic studies, and 2) degree of attrition (beta), which can vary between 0 (no attrition) and 10 (maximum attrition) and relates the survivorship of bone elements to their maximum bone density. Starting from uniform prior probability distribution functions of alpha and beta, a Monte Carlo Markov Chain sampling based on a random walk Metropolis-Hasting algorithm is adopted to derive the posterior probability distribution functions, which are then available for interpretation. During this process, the likelihood of obtaining the observed percentages of MAU given a pair of parameter values is estimated by the inverse of the Chi2 statistic, multiplied by the proportion of elements within a 1 percent of the observed value. See Ana B. Marin-Arroyo, David Ocio (2018).<doi:10.1080/08912963.2017.1336620>.

This package implements the Bayesian Synthetic Control method for causal inference in comparative case studies. This package provides tools for estimating treatment effects in settings with a single treated unit and multiple control units, allowing for uncertainty quantification and flexible modeling of time-varying effects. The methodology is based on the paper by Vives and Martinez (2022) <doi:10.48550/arXiv.2206.01779>.

Implementation of algorithms for cutting numerical values exhibiting a potentially highly skewed distribution into evenly distributed groups (bins). This functionality can be applied for binning discrete values, such as counts, as well as for discretization of continuous values, for example, during generation of features used in machine learning algorithms.

This package provides functions to reconstruct, generate, and simulate synchronous, asynchronous, probabilistic, and temporal Boolean networks. Provides also functions to analyze and visualize attractors in Boolean networks <doi:10.1093/bioinformatics/btq124>.

Best Orthogonalized Subset Selection (BOSS) is a least-squares (LS) based subset selection method, that performs best subset selection upon an orthogonalized basis of ordered predictors, with the computational effort of a single ordinary LS fit. This package provides a highly optimized implementation of BOSS and estimates a heuristic degrees of freedom for BOSS, which can be plugged into an information criterion (IC) such as AICc in order to select the subset from candidates. It provides various choices of IC, including AIC, BIC, AICc, Cp and GCV. It also implements the forward stepwise selection (FS) with no additional computational cost, where the subset of FS is selected via cross-validation (CV). CV is also an option for BOSS. For details see: Tian, Hurvich and Simonoff (2021), "On the Use of Information Criteria for Subset Selection in Least Squares Regression", <arXiv:1911.10191>.

Several implementations of non-parametric stable bootstrap-based techniques to determine the numbers of components for Partial Least Squares linear or generalized linear regression models as well as and sparse Partial Least Squares linear or generalized linear regression models. The package collects techniques that were published in a book chapter (Magnanensi et al. 2016, The Multiple Facets of Partial Least Squares and Related Methods', <doi:10.1007/978-3-319-40643-5_18>) and two articles (Magnanensi et al. 2017, Statistics and Computing', <doi:10.1007/s11222-016-9651-4>) and (Magnanensi et al. 2021, Frontiers in Applied Mathematics and Statistics', <doi:10.3389/fams.2021.693126>).