This package implements the efficient algorithm by Ortmann and Brandes (2017) <doi:10.1007/s41109-017-0027-2> to compute the orbit-aware frequency distribution of induced and non-induced quads, i.e. subgraphs of size four. Given an edge matrix, data frame, or a graph object (e.g., igraph'), the orbit-aware counts are computed respective each of the edges and nodes.

Analyze repertory grids, a qualitative-quantitative data collection technique devised by George A. Kelly in the 1950s. Today, grids are used across various domains ranging from clinical psychology to marketing. The package contains functions to quantitatively analyze and visualize repertory grid data (e.g. Fransella', Bell', & Bannister', 2004, ISBN: 978-0-470-09080-0). The package is part of the The package is part of the <https://openrepgrid.org/> project.

Evaluates the Owen Q-function for an integer value of the degrees of freedom, by applying Owen's algorithm (1965) <doi:10.1093/biomet/52.3-4.437>. It is useful for the calculation of the power of equivalence tests.

Transactions occurring for a UK-based and registered, non-store online retail between 01/12/2010 and 09/12/2011 (Chen et. al., 2012, <doi:10.1145/1835804.1835882>). This dataset is included in this package with the donor's permission, Dr. Daqing Chen.

This package provides routines for finding an Optimal System of Distinct Representatives (OSDR), as defined by D.Gale (1968) <doi:10.1016/S0021-9800(68)80039-0>.

Generalise the starting point of the array index.

Facilitates the creation of intuitive figures to describe metabolomics data by utilizing Kyoto Encyclopedia of Genes and Genomes (KEGG) hierarchy data, and gathers functional orthology and gene data from the KEGG-REST API.

Interface to make HTTP requests to OpenBlender API services. Go to <https://openblender.io> for more information.

The client streamlines access to the services provided by <https://api.openrouteservice.org>. It allows you to painlessly query for directions, isochrones, time-distance matrices, geocoding, elevation, points of interest, and more.

Growing collection of helper functions for point pattern analysis. Most functions are designed to work with the spatstat (<http://spatstat.org>) package. The focus of most functions are either null models or summary functions for spatial point patterns. For a detailed description of all null models and summary functions, see Wiegand and Moloney (2014, ISBN:9781420082548).

Identifies the optimal transformation of a surrogate marker and estimates the proportion of treatment explained (PTE) by the optimally-transformed surrogate at an earlier time point when the primary outcome of interest is a censored time-to-event outcome; details are described in Wang et al (2021) <doi:10.1002/sim.9185>.

Estimates ordered probit switching regression models - a Heckman type selection model with an ordinal selection and continuous outcomes. Different model specifications are allowed for each treatment/regime. For more details on the method, see Wang & Mokhtarian (2024) <doi:10.1016/j.tra.2024.104072> or Chiburis & Lokshin (2007) <doi:10.1177/1536867X0700700202>.

This package provides a tool for interactive exploration of the results from omics experiments to facilitate novel discoveries from high-throughput biology. The software includes R functions for the bioinformatician to deposit study metadata and the outputs from statistical analyses (e.g. differential expression, enrichment). These results are then exported to an interactive JavaScript dashboard that can be interrogated on the user's local machine or deployed online to be explored by collaborators. The dashboard includes sortable tables, interactive plots including network visualization, and fine-grained filtering based on statistical significance.

Apply unsupervised segmentation algorithms included in Orfeo ToolBox software (<https://www.orfeo-toolbox.org/>), such as mean shift or watershed segmentation.

This package provides a method that analyzes quality control metrics from multi-sample genomic sequencing studies and nominates poor quality samples for exclusion. Per sample quality control data are transformed into z-scores and aggregated. The distribution of aggregated z-scores are modelled using parametric distributions. The parameters of the optimal model, selected either by goodness-of-fit statistics or user-designation, are used for outlier nomination. Two implementations of the Cosine Similarity Outlier Detection algorithm are provided with flexible parameters for dataset customization.

This package provides unified workflows for quality control, normalization, and visualization of proteomic and metabolomic data. The package simplifies preprocessing through automated imputation, scaling, and principal component analysis (PCA)-based exploratory analysis, enabling researchers to prepare omics datasets efficiently for downstream statistical and machine learning analyses.

Perform a Bayesian estimation of the ordinal exploratory Higher-order General Diagnostic Model (OHOEGDM) for Polytomous Data described by Culpepper, S. A. and Balamuta, J. J. (2021) <doi:10.1080/00273171.2021.1985949>.

This package provides functions for transforming and viewing 2-D and 3-D (oceanographic) data and model output.

We proposes a framework that provides real time support for early detection of anomalous series within a large collection of streaming time series data. By definition, anomalies are rare in comparison to a system's typical behaviour. We define an anomaly as an observation that is very unlikely given the forecast distribution. The algorithm first forecasts a boundary for the system's typical behaviour using a representative sample of the typical behaviour of the system. An approach based on extreme value theory is used for this boundary prediction process. Then a sliding window is used to test for anomalous series within the newly arrived collection of series. Feature based representation of time series is used as the input to the model. To cope with concept drift, the forecast boundary for the system's typical behaviour is updated periodically. More details regarding the algorithm can be found in Talagala, P. D., Hyndman, R. J., Smith-Miles, K., et al. (2019) <doi:10.1080/10618600.2019.1617160>.

We consider the problem of estimating two isotonic regression curves g1* and g2* under the constraint that they are ordered, i.e. g1* <= g2*. Given two sets of n data points y_1, ..., y_n and z_1, ..., z_n that are observed at (the same) deterministic design points x_1, ..., x_n, the estimates are obtained by minimizing the Least Squares criterion L(a, b) = sum_i=1^n (y_i - a_i)^2 w1(x_i) + sum_i=1^n (z_i - b_i)^2 w2(x_i) over the class of pairs of vectors (a, b) such that a and b are isotonic and a_i <= b_i for all i = 1, ..., n. We offer two different approaches to compute the estimates: a projected subgradient algorithm where the projection is calculated using a PAVA as well as Dykstra's cyclical projection algorithm.

Enables the usage of the OpenDota API from <https://www.opendota.com/>, get game lists, and download JSON's of parsed replays from the OpenDota API. Also has functionality to execute own code to extract the specific parts of the JSON file.

This package provides a set of commands to manage an abstract optimization method. The goal is to provide a building block for a large class of specialized optimization methods. This package manages: the number of variables, the minimum and maximum bounds, the number of non linear inequality constraints, the cost function, the logging system, various termination criteria, etc...

Import data from Our World in Data', an organisation which publishes research and data on global economic and social issues.

This package provides tools for annotating characters (character matrices) with anatomical and phenotype ontologies. Includes functions for visualising character annotations and creating simple queries using ontological relationships.