Statistical inference for quadratic functional of the moderate-dimensional linear model in Guo and Cheng (2021) <DOI:10.1080/01621459.2021.1893177>.

This is an EM algorithm based method for imputation of missing values in multivariate normal time series. The imputation algorithm accounts for both spatial and temporal correlation structures. Temporal patterns can be modeled using an ARIMA(p,d,q), optionally with seasonal components, a non-parametric cubic spline or generalized additive models with exogenous covariates. This algorithm is specially tailored for climate data with missing measurements from several monitors along a given region.

Computing transitive (and non-transitive) index numbers (Coelli et al., 2005 <doi:10.1007/b136381>) for cross-sections and panel data. For the calculation of transitive indexes, the EKS (Coelli et al., 2005 <doi:10.1007/b136381>; Rao et al., 2002 <doi:10.1007/978-1-4615-0851-9_4>) and Minimum spanning tree (Hill, 2004 <doi:10.1257/0002828043052178>) methods are implemented. Traditional fixed-base and chained indexes, and their growth rates, can also be derived using the Paasche, Laspeyres, Fisher and Tornqvist formulas.

This package provides functions that (1) fit multivariate discrete distributions, (2) generate random numbers from multivariate discrete distributions, and (3) run regression and penalized regression on the multivariate categorical response data. Implemented models include: multinomial logit model, Dirichlet multinomial model, generalized Dirichlet multinomial model, and negative multinomial model. Making the best of the minorization-maximization (MM) algorithm and Newton-Raphson method, we derive and implement stable and efficient algorithms to find the maximum likelihood estimates. On a multi-core machine, multi-threading is supported.

Wrapper for minepy implementation of Maximal Information-based Nonparametric Exploration statistics (MIC and MINE family). Detailed information of the ANSI C implementation of minepy can be found at <http://minepy.readthedocs.io/en/latest>.

Programmatic interface to several NASA Earth Observation OPeNDAP servers (Open-source Project for a Network Data Access Protocol) (<https://www.opendap.org/>). Allows for easy downloads of MODIS subsets, as well as other Earth Observation datacubes, in a time-saving and efficient way : by sampling it at the very downloading phase (spatially, temporally and dimensionally).

Package with multivariate analysis methodologies for experiment evaluation. The package estimates dissimilarity measures, builds dendrograms, obtains MANOVA, principal components, canonical variables, etc. (Pacote com metodologias de analise multivariada para avaliação de experimentos. O pacote estima medidas de dissimilaridade, construi de dendogramas, obtem a MANOVA, componentes principais, variaveis canonicas, etc.).

Automated cell type annotation for single-cell RNA sequencing data using consensus predictions from multiple large language models. Integrates with Seurat objects and provides uncertainty quantification for annotations. Supports various LLM providers including OpenAI, Anthropic, and Google. For details see Yang et al. (2025) <doi:10.1101/2025.04.10.647852>.

Test the marginal correlation between a scalar response variable with a vector of explanatory variables using the max-type test with bootstrap. The test is based on the max-type statistic and its asymptotic distribution under the null hypothesis of no marginal correlation. The bootstrap procedure is used to approximate the null distribution of the test statistic. The package provides a function for performing the test. For more technical details, refer to Zhang and Laber (2014) <doi:10.1080/01621459.2015.1106403>.

Conduct random forests-based meta-analysis, obtain partial dependence plots for metaforest and classic meta-analyses, and cross-validate and tune metaforest- and classic meta-analyses in conjunction with the caret package. A requirement of classic meta-analysis is that the studies being aggregated are conceptually similar, and ideally, close replications. However, in many fields, there is substantial heterogeneity between studies on the same topic. Classic meta-analysis lacks the power to assess more than a handful of univariate moderators. MetaForest, by contrast, has substantial power to explore heterogeneity in meta-analysis. It can identify important moderators from a larger set of potential candidates (Van Lissa, 2020). This is an appealing quality, because many meta-analyses have small sample sizes. Moreover, MetaForest yields a measure of variable importance which can be used to identify important moderators, and offers partial prediction plots to explore the shape of the marginal relationship between moderators and effect size.

Fits mixed Poisson regression models (Poisson-Inverse Gaussian or Negative-Binomial) on data sets with response variables being count data. The models can have varying precision parameter, where a linear regression structure (through a link function) is assumed to hold on the precision parameter. The Expectation-Maximization algorithm for both these models (Poisson Inverse Gaussian and Negative Binomial) is an important contribution of this package. Another important feature of this package is the set of functions to perform global and local influence analysis. See Barreto-Souza and Simas (2016) <doi:10.1007/s11222-015-9601-6> for further details.

Offering enhanced statistical power compared to traditional hypothesis testing methods, informative hypothesis testing allows researchers to explicitly model their expectations regarding the relationships among parameters. An important software tool for this framework is restriktor'. The mmirestriktor package provides shiny web applications to implement some of the basic functionality of restriktor'. The mmirestriktor() function launches a shiny application for fitting and analyzing models with constraints. The FbarCards() function launches a card game application which can help build intuition about informative hypothesis testing. The iht_interpreter() helps interpret informative hypothesis testing results based on guidelines in Vanbrabant and Rosseel (2020) <doi:10.4324/9780429273872-14>.

This package provides a suite of tools for transforming an existing workflow into a self-documenting pipeline with very minimal upfront costs. Segments of the pipeline are specified in much the same way a Make rule is, by declaring an executable recipe (which might be an R script), along with the corresponding targets and dependencies. When the entire pipeline is run through, only those recipes that need to be executed will be. Meanwhile, execution metadata is captured behind the scenes for later inspection.

It implements a new procedure of variable selection in the context of redundancy between explanatory variables, which holds true with high dimensional data (Grimonprez et al. (2023) <doi:10.18637/jss.v106.i03>).

The Markov Decision Processes (MDP) toolbox proposes functions related to the resolution of discrete-time Markov Decision Processes: finite horizon, value iteration, policy iteration, linear programming algorithms with some variants and also proposes some functions related to Reinforcement Learning.

Extends the base classes and methods of caret package for integration of base learners. The user can input the number of different base learners, and specify the final learner, along with the train-validation-test data partition split ratio. The predictions on the unseen new data is the resultant of the ensemble meta-learning <https://machinelearningmastery.com/stacking-ensemble-machine-learning-with-python/> of the heterogeneous learners aimed to reduce the generalization error in the predictive models. It significantly lowers the barrier for the practitioners to apply heterogeneous ensemble learning techniques in an amateur fashion to their everyday predictive problems.

This package provides a minimal, light-weight set of tools for producing nice looking maps in R, with support for map projections. See Brown (2016) <doi:10.32614/RJ-2016-005>.

Model based clustering using the multivariate multiple Scaled t (MST) and multivariate multiple scaled contaminated normal (MSCN) distributions. The MST is an extension of the multivariate Student-t distribution to include flexible tail behaviors, Forbes, F. & Wraith, D. (2014) <doi:10.1007/s11222-013-9414-4>. The MSCN represents a heavy-tailed generalization of the multivariate normal (MN) distribution to model elliptical contoured scatters in the presence of mild outliers (also referred to as "bad" points) and automatically detect bad points, Punzo, A. & Tortora, C. (2021) <doi:10.1177/1471082X19890935>.

Comprehensive toolkit for Environmental Phillips Curve analysis featuring multidimensional instrumental variable creation, transfer entropy causal discovery, network analysis, and state-of-the-art econometric methods. Implements geographic, technological, migration, geopolitical, financial, and natural risk instruments with robust diagnostics and visualization. Provides 24 different instrumental variable approaches with empirical validation. Methods based on Phillips (1958) <doi:10.1111/j.1468-0335.1958.tb00003.x>, transfer entropy by Schreiber (2000) <doi:10.1103/PhysRevLett.85.461>, and weak instrument tests by Stock and Yogo (2005) <doi:10.1017/CBO9780511614491.006>.

Estimates random effect latent measurement models, wherein the loadings, residual variances, intercepts, latent means, and latent variances all vary across groups. The random effect variances of the measurement parameters are then modeled using a hierarchical inclusion model, wherein the inclusion of the variances (i.e., whether it is effectively zero or non-zero) is informed by similar parameters (of the same type, or of the same item). This additional hierarchical structure allows the evidence in favor of partial invariance to accumulate more quickly, and yields more certain decisions about measurement invariance. Martin, Williams, and Rast (2020) <doi:10.31234/osf.io/qbdjt>.

Large-scale matrix-variate data have been widely observed nowadays in various research areas such as finance, signal processing and medical imaging. Modelling matrix-valued data by matrix-elliptical family not only provides a flexible way to handle heavy-tail property and tail dependencies, but also maintains the intrinsic row and column structure of random matrices. We proposed a new tool named matrix Kendall's tau which is efficient for analyzing random elliptical matrices. By applying this new type of Kendellâ s tau to the matrix elliptical factor model, we propose a Matrix-type Robust Two-Step (MRTS) method to estimate the loading and factor spaces. See the details in He at al. (2022) <arXiv:2207.09633>. In this package, we provide the algorithms for calculating sample matrix Kendall's tau, the MRTS method and the Matrix Kendall's tau Eigenvalue-Ratio (MKER) method which is used for determining the number of factors.

Package for estimating, analyzing, and forecasting multi-country macro-finance affine term structure models (ATSMs). All setups build on the single-country unspanned macroeconomic risk framework from Joslin, Priebsch, and Singleton (2014, JF) <doi:10.1111/jofi.12131>. Multicountry extensions by Jotikasthira, Le, and Lundblad (2015, JFE) <doi:10.1016/j.jfineco.2014.09.004>, Candelon and Moura (2023, EM) <doi:10.1016/j.econmod.2023.106453>, and Candelon and Moura (2024, JFEC) <doi:10.1093/jjfinec/nbae008> are also available. The package also provides tools for bias correction as in Bauer Rudebusch and Wu (2012, JBES) <doi:10.1080/07350015.2012.693855>, bootstrap analysis, and several graphical/numerical outputs.

Implementation of the sampling and aggregation method for the covariate shift maximin effect, which was proposed in <doi:10.48550/arXiv.2011.07568>. It constructs the confidence interval for any linear combination of the high-dimensional maximin effect.

This package provides a series of data analysis approaches for microbiome omics data based on the R6 class. The classes are designed for data preprocessing, taxa abundance plotting, alpha diversity analysis, beta diversity analysis, differential abundance test, null model analysis, network analysis, machine learning, environmental data analysis and functional analysis.