Optimal Subset Cardinality Regression (OSCAR) models offer regularized linear regression using the L0-pseudonorm, conventionally known as the number of non-zero coefficients. The package estimates an optimal subset of features using the L0-penalization via cross-validation, bootstrapping and visual diagnostics. Effective Fortran implementations are offered along the package for finding optima for the DC-decomposition, which is used for transforming the discrete L0-regularized optimization problem into a continuous non-convex optimization task. These optimization modules include DBDC ('Double Bundle method for nonsmooth DC optimization as described in Joki et al. (2018) <doi:10.1137/16M1115733>) and LMBM ('Limited Memory Bundle Method for large-scale nonsmooth optimization as in Haarala et al. (2004) <doi:10.1080/10556780410001689225>). The OSCAR models are comprehensively exemplified in Halkola et al. (2023) <doi:10.1371/journal.pcbi.1010333>). Multiple regression model families are supported: Cox, logistic, and Gaussian.

Represents the basis functions for B-splines in a simple matrix formulation that facilitates, taking integrals, derivatives, and making orthogonal the basis functions.

Outlier detection method that flags suspicious values within observations, constrasting them against the normal values in a user-readable format, potentially describing conditions within the data that make a given outlier more rare. Full procedure is described in Cortes (2020) <doi:10.48550/arXiv.2001.00636>. Loosely based on the GritBot <https://www.rulequest.com/gritbot-info.html> software.

Intended to create standard human-in-the-loop validity tests for typical automated content analysis such as topic modeling and dictionary-based methods. This package offers a standard workflow with functions to prepare, administer and evaluate a human-in-the-loop validity test. This package provides functions for validating topic models using word intrusion, topic intrusion (Chang et al. 2009, <https://papers.nips.cc/paper/3700-reading-tea-leaves-how-humans-interpret-topic-models>) and word set intrusion (Ying et al. 2021) <doi:10.1017/pan.2021.33> tests. This package also provides functions for generating gold-standard data which are useful for validating dictionary-based methods. The default settings of all generated tests match those suggested in Chang et al. (2009) and Song et al. (2020) <doi:10.1080/10584609.2020.1723752>.

This package provides functionalities and data structures to retrieve, analyze and visualize aviation data. It includes a client interface to the OpenSky API <https://opensky-network.org>. It allows retrieval of flight information, as well as aircraft state vectors.

Medication adherence, defined as medication-taking behavior that aligns with the agreed-upon treatment protocol, is critical for realizing the benefits of prescription medications. Medication adherence can be assessed using electronic adherence monitoring devices (EAMDs), pill bottles or boxes that contain a computer chip that records the date and time of each opening (or â actuationâ ). Before researchers can use EAMD data, they must apply a series of decision rules to transform actuation data into adherence data. The purpose of this R package ('oncmap') is to transform EAMD actuations in the form of a raw .csv file, information about the patient, regimen, and non-monitored periods into two daily adherence values -- Dose Taken and Correct Dose Taken.

The Open Bodem Index (OBI) is a method to evaluate the quality of soils of agricultural fields in The Netherlands and the sustainability of the current agricultural practices. The OBI score is based on four main criteria: chemical, physical, biological and management, which consist of more than 21 indicators. By providing results of a soil analysis and management info the OBIC package can be use to calculate he scores, indicators and derivatives that are used by the OBI. More information about the Open Bodem Index can be found at <https://openbodemindex.nl/>.

Solves penalized least squares problems for big tall data using the orthogonalizing EM algorithm of Xiong et al. (2016) <doi:10.1080/00401706.2015.1054436>. The main fitting function is oem() and the functions cv.oem() and xval.oem() are for cross validation, the latter being an accelerated cross validation function for linear models. The big.oem() function allows for out of memory fitting. A description of the underlying methods and code interface is described in Huling and Chien (2022) <doi:10.18637/jss.v104.i06>.

Fits community site occupancy models to environmental DNA metabarcoding data collected using spatially-replicated survey design. Model fitting results can be used to evaluate and compare the effectiveness of species detection to find an efficient survey design. Reference: Fukaya et al. (2022) <doi:10.1111/2041-210X.13732>, Fukaya and Hasebe (2025) <doi:10.1002/1438-390X.12219>.

This package provides functions for quickly creating R and Python scripts, as well as Rmarkdown or Quarto documents with automatically assigned name prefixes. Prefixes are either file counts (e.g. "001") or dates (e.g. "2022-09-26").

This package provides a framework for the optimization of breeding programs via optimum contribution selection and mate allocation. An easy to use set of function for computation of optimum contributions of selection candidates, and of the population genetic parameters to be optimized. These parameters can be estimated using pedigree or genotype information, and include kinships, kinships at native haplotype segments, and breed composition of crossbred individuals. They are suitable for managing genetic diversity, removing introgressed genetic material, and accelerating genetic gain. Additionally, functions are provided for computing genetic contributions from ancestors, inbreeding coefficients, the native effective size, the native genome equivalent, pedigree completeness, and for preparing and plotting pedigrees. The methods are described in:\n Wellmann, R., and Pfeiffer, I. (2009) <doi:10.1017/S0016672309000202>.\n Wellmann, R., and Bennewitz, J. (2011) <doi:10.2527/jas.2010-3709>.\n Wellmann, R., Hartwig, S., Bennewitz, J. (2012) <doi:10.1186/1297-9686-44-34>.\n de Cara, M. A. R., Villanueva, B., Toro, M. A., Fernandez, J. (2013) <doi:10.1111/mec.12560>.\n Wellmann, R., Bennewitz, J., Meuwissen, T.H.E. (2014) <doi:10.1017/S0016672314000196>.\n Wellmann, R. (2019) <doi:10.1186/s12859-018-2450-5>.

Applies an objective Bayesian method to the Mb capture-recapture model to estimate the population size N. The Mb model is a class of capture-recapture methods used to account for variations in capture probability due to animal behavior. Under the Mb formulation, the initial capture of an animal may effect the probability of subsequent captures due to their becoming "trap happy" or "trap shy.".

Streamlines the post-processing, summarization, and visualization of outbreaker2 output via a suite of helper functions. Facilitates tidy manipulation of posterior samples, integration with case metadata, generation of diagnostic plots and summary statistics.

Get operating characteristics of one-arm clinical trial designs for time-to-event endpoint through simulation and perform analysis with time-to-event data.

Helper functions for Org files (<https://orgmode.org/>): a generic function toOrg for transforming R objects into Org markup (most useful for data frames; there are also methods for Dates/POSIXt) and a function to read Org tables into data frames.

Open the current working directory (or a given directory path) in your computer's file manager.

Allows you to easily execute expensive compute operations only once, and save the resulting object to disk.

Quaternions and Octonions are four- and eight- dimensional extensions of the complex numbers. They are normed division algebras over the real numbers and find applications in spatial rotations (quaternions), and string theory and relativity (octonions). The quaternions are noncommutative and the octonions nonassociative. See the package vignette for more details.

Non-spatial and spatial open-population capture-recapture analysis.

Obtain and evaluate various optimal designs for the 3, 4, and 5-parameter logistic models. The optimal designs are obtained based on the numerical algorithm in Hyun, Wong, Yang (2018) <doi:10.18637/jss.v083.i05>.

Ing and Lai (2011) <doi:10.5705/ss.2010.081> proposed a high-dimensional model selection procedure that comprises three steps: orthogonal greedy algorithm (OGA), high-dimensional information criterion (HDIC), and Trim. The first two steps, OGA and HDIC, are used to sequentially select input variables and determine stopping rules, respectively. The third step, Trim, is used to delete irrelevant variables remaining in the second step. This package aims at fitting a high-dimensional linear regression model via OGA+HDIC+Trim.

This package infers Boolean rules among cis-regulatory regions using paired chromatin accessibility and gene expression data at bulk and single-cell levels. Links regulatory regions to target genes, providing insights into gene regulation mechanisms.

This package provides a collection of general-purpose helper functions that I (and maybe others) find useful when developing data science software. Includes tools for simulation, data transformation, input validation, and more.

Seamlessly build and manipulate graph structures, leveraging its high-performance methods for filtering, joining, and mutating data. Ensures that mutations and changes to the graph are performed in place, streamlining your workflow for optimal productivity.